Homo sapiens

5 known processes

GCSH

glycine cleavage system protein H (aminomethyl carrier)

(Aliases: NKH,GCE)

GCSH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forelimb morphogenesis GO:0035136 4 0.435
embryonic hindlimb morphogenesis GO:0035116 2 0.119
cellular amino acid metabolic process GO:0006520 116 0.094
regulation of apoptotic signaling pathway GO:2001233 175 0.079
regulation of leukocyte activation GO:0002694 115 0.076
asymmetric stem cell division GO:0098722 1 0.075
positive regulation of cell death GO:0010942 263 0.068
hindlimb morphogenesis GO:0035137 2 0.064
positive regulation of apoptotic process GO:0043065 246 0.059
hematopoietic or lymphoid organ development GO:0048534 186 0.056
cellular amine metabolic process GO:0044106 41 0.056
negative regulation of myeloid cell differentiation GO:0045638 42 0.051
post embryonic development GO:0009791 2 0.050
amine metabolic process GO:0009308 44 0.047
positive regulation of programmed cell death GO:0043068 249 0.047
histone modification GO:0016570 251 0.046
negative regulation of immune system process GO:0002683 136 0.046
regulation of cell activation GO:0050865 125 0.044
stem cell division GO:0017145 2 0.044
cellular ketone metabolic process GO:0042180 80 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.041
apoptotic signaling pathway GO:0097190 268 0.040
multicellular organismal aging GO:0010259 3 0.039
regulation of t cell activation GO:0050863 77 0.037
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.037
positive regulation of leukocyte differentiation GO:1902107 37 0.036
chromatin organization GO:0006325 351 0.035
negative regulation of cell cycle GO:0045786 193 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
negative regulation of cell proliferation GO:0008285 228 0.033
determination of adult lifespan GO:0008340 2 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
regulation of cell differentiation GO:0045595 393 0.031
negative regulation of developmental process GO:0051093 247 0.031
positive regulation of apoptotic signaling pathway GO:2001235 70 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
lymphocyte activation GO:0046649 133 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
embryonic morphogenesis GO:0048598 85 0.029
positive regulation of t cell activation GO:0050870 54 0.029
protein acylation GO:0043543 138 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
ossification GO:0001503 121 0.029
oxidation reduction process GO:0055114 396 0.028
cellular response to endogenous stimulus GO:0071495 336 0.028
positive regulation of immune system process GO:0002684 283 0.028
regulation of cell cycle GO:0051726 393 0.027
urogenital system development GO:0001655 65 0.027
positive regulation of leukocyte activation GO:0002696 80 0.027
positive regulation of alpha beta t cell activation GO:0046635 10 0.027
regulation of cellular response to growth factor stimulus GO:0090287 76 0.026
cell cycle arrest GO:0007050 71 0.026
female gamete generation GO:0007292 2 0.026
nervous system development GO:0007399 293 0.025
connective tissue development GO:0061448 39 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
regulation of lymphocyte activation GO:0051249 103 0.025
lipid metabolic process GO:0006629 381 0.025
regulation of chondrocyte differentiation GO:0032330 9 0.025
cell activation GO:0001775 213 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
oogenesis GO:0048477 2 0.024
negative regulation of cell differentiation GO:0045596 171 0.024
dephosphorylation GO:0016311 209 0.023
central nervous system development GO:0007417 123 0.023
t cell activation GO:0042110 99 0.023
positive regulation of lymphocyte activation GO:0051251 73 0.023
positive regulation of cell activation GO:0050867 81 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
negative regulation of growth GO:0045926 97 0.022
positive regulation of chondrocyte differentiation GO:0032332 4 0.022
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.022
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.022
guanosine containing compound metabolic process GO:1901068 244 0.022
immune system development GO:0002520 195 0.022
leukocyte activation GO:0045321 164 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
covalent chromatin modification GO:0016569 254 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of growth GO:0040008 165 0.021
regulation of ossification GO:0030278 58 0.021
organophosphate catabolic process GO:0046434 430 0.020
peptidyl lysine acetylation GO:0018394 101 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
dna replication GO:0006260 116 0.020
regulation of leukocyte differentiation GO:1902105 61 0.020
ribonucleotide catabolic process GO:0009261 405 0.019
cartilage development GO:0051216 31 0.019
dna repair GO:0006281 198 0.019
chromatin modification GO:0016568 298 0.019
cellular lipid metabolic process GO:0044255 303 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
limb morphogenesis GO:0035108 16 0.019
peptidyl lysine modification GO:0018205 144 0.018
protein localization to organelle GO:0033365 280 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
microtubule based process GO:0007017 210 0.018
immune response GO:0006955 307 0.018
cell division GO:0051301 168 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.017
cell growth GO:0016049 160 0.017
purine containing compound catabolic process GO:0072523 411 0.017
hemopoiesis GO:0030097 180 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
nucleoside catabolic process GO:0009164 408 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.016
histone acetylation GO:0016573 93 0.016
mesonephros development GO:0001823 17 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
response to transforming growth factor beta GO:0071559 94 0.016
rho protein signal transduction GO:0007266 26 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
spermatid differentiation GO:0048515 4 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
leukocyte differentiation GO:0002521 98 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
neuromuscular junction development GO:0007528 3 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
innate immune response GO:0045087 178 0.015
kidney development GO:0001822 53 0.015
endosomal transport GO:0016197 129 0.015
protein maturation GO:0051604 233 0.015
myeloid cell differentiation GO:0030099 117 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
spermatid development GO:0007286 4 0.014
transmembrane transport GO:0055085 399 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
regulation of gtpase activity GO:0043087 180 0.014
negative regulation of cell death GO:0060548 345 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
protein processing GO:0016485 226 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
ras protein signal transduction GO:0007265 73 0.013
memory GO:0007613 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
fat cell differentiation GO:0045444 32 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
vesicle mediated transport GO:0016192 371 0.013
locomotory behavior GO:0007626 1 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
mitotic cell cycle process GO:1903047 286 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
fatty acid metabolic process GO:0006631 115 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.012
regulation of protein localization GO:0032880 296 0.012
cellular homeostasis GO:0019725 196 0.012
regulation of cell growth GO:0001558 135 0.012
double strand break repair GO:0006302 101 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of transferase activity GO:0051338 355 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
small molecule catabolic process GO:0044282 92 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
single organism reproductive process GO:0044702 98 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
response to organic cyclic compound GO:0014070 204 0.012
segmentation GO:0035282 4 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
negative regulation of transferase activity GO:0051348 124 0.011
gtp catabolic process GO:0006184 237 0.011
single organism cellular localization GO:1902580 332 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
regulation of cartilage development GO:0061035 12 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of dephosphorylation GO:0035303 96 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
regulation of alpha beta t cell differentiation GO:0046637 5 0.011
regulation of fat cell differentiation GO:0045598 23 0.011
regulation of cellular response to stress GO:0080135 244 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
carboxylic acid catabolic process GO:0046395 71 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of peptidase activity GO:0052547 180 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
protein acetylation GO:0006473 116 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
limb development GO:0060173 23 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
positive regulation of secretion GO:0051047 116 0.011
carbohydrate metabolic process GO:0005975 207 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.010
negative regulation of cellular protein metabolic process GO:0032269 353 0.010
embryonic limb morphogenesis GO:0030326 9 0.010
multi organism reproductive process GO:0044703 54 0.010
response to external biotic stimulus GO:0043207 261 0.010
positive regulation of developmental process GO:0051094 314 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
regulation of protein kinase activity GO:0045859 289 0.010
cellular protein complex assembly GO:0043623 188 0.010
lipid biosynthetic process GO:0008610 177 0.010
negative regulation of proteolysis GO:0045861 132 0.010
hindbrain development GO:0030902 3 0.010
appendage morphogenesis GO:0035107 16 0.010
membrane organization GO:0061024 292 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
rna processing GO:0006396 255 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010

GCSH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.048
inherited metabolic disorder DOID:655 242 0.035
central nervous system disease DOID:331 186 0.016
nervous system disease DOID:863 431 0.016
sensory system disease DOID:0050155 203 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
amino acid metabolic disorder DOID:9252 50 0.005
glycine encephalopathy DOID:9268 3 0.000