Homo sapiens

70 known processes

DROSHA

drosha, ribonuclease type III

(Aliases: RNASE3L,ETOHI2,RANSE3L,HSA242976,RN3,RNASEN)

DROSHA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ncrna processing GO:0034470 83 0.638
rna processing GO:0006396 255 0.465
ncrna metabolic process GO:0034660 108 0.348
gene silencing by mirna GO:0035195 23 0.187
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.162
female gamete generation GO:0007292 2 0.140
Fly
dsrna fragmentation GO:0031050 13 0.130
regulation of cellular component biogenesis GO:0044087 281 0.119
cellular response to organic cyclic compound GO:0071407 127 0.118
posttranscriptional gene silencing by rna GO:0035194 25 0.113
head development GO:0060322 108 0.106
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.097
cytoplasmic transport GO:0016482 379 0.094
multicellular organismal aging GO:0010259 3 0.083
oogenesis GO:0048477 2 0.080
Fly
brain development GO:0007420 97 0.075
Fly
response to organic cyclic compound GO:0014070 204 0.075
protein localization to organelle GO:0033365 280 0.065
cellular macromolecular complex assembly GO:0034622 324 0.064
production of small rna involved in gene silencing by rna GO:0070918 13 0.059
establishment of protein localization to organelle GO:0072594 172 0.059
post embryonic development GO:0009791 2 0.058
determination of adult lifespan GO:0008340 2 0.054
response to nitrogen compound GO:1901698 184 0.052
vesicle mediated transport GO:0016192 371 0.050
actin filament based process GO:0030029 224 0.049
regulation of protein transport GO:0051223 213 0.046
meiosis i GO:0007127 4 0.046
intracellular protein transport GO:0006886 270 0.046
posttranscriptional gene silencing GO:0016441 25 0.045
rna phosphodiester bond hydrolysis GO:0090501 35 0.042
regulation of meiotic cell cycle GO:0051445 4 0.042
regulation of intracellular transport GO:0032386 195 0.041
positive regulation of intracellular protein transport GO:0090316 76 0.041
regulation of protein localization GO:0032880 296 0.040
growth GO:0040007 202 0.040
nucleocytoplasmic transport GO:0006913 176 0.040
anatomical structure formation involved in morphogenesis GO:0048646 284 0.040
Fly
cellular amino acid metabolic process GO:0006520 116 0.039
adult locomotory behavior GO:0008344 1 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
primary mirna processing GO:0031053 3 0.038
cellular response to dsrna GO:0071359 19 0.035
regulation of establishment of protein localization GO:0070201 242 0.034
organelle assembly GO:0070925 176 0.033
nervous system development GO:0007399 293 0.033
Fly
mitotic cell cycle GO:0000278 326 0.033
Worm
positive regulation of cellular component biogenesis GO:0044089 158 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
single organism reproductive process GO:0044702 98 0.031
Fly
mitotic cell cycle phase transition GO:0044772 162 0.030
response to dsrna GO:0043331 25 0.030
ribonucleoprotein complex biogenesis GO:0022613 116 0.029
oocyte differentiation GO:0009994 2 0.029
Fly
mrna metabolic process GO:0016071 175 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
regeneration GO:0031099 4 0.027
microtubule based process GO:0007017 210 0.027
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
positive regulation of intracellular transport GO:0032388 104 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
neuromuscular junction development GO:0007528 3 0.024
positive regulation of protein transport GO:0051222 135 0.024
positive regulation of transport GO:0051050 336 0.023
locomotory behavior GO:0007626 1 0.023
amine metabolic process GO:0009308 44 0.023
protein localization to nucleus GO:0034504 136 0.022
regulation of growth GO:0040008 165 0.022
segmentation GO:0035282 4 0.022
regulation of cell cycle phase transition GO:1901987 126 0.021
single organism cellular localization GO:1902580 332 0.021
cellular ketone metabolic process GO:0042180 80 0.021
regulation of dna metabolic process GO:0051052 153 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of cell cycle process GO:0010564 266 0.021
positive regulation of growth GO:0045927 58 0.021
behavior GO:0007610 112 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
cell development GO:0048468 328 0.020
Fly
organophosphate catabolic process GO:0046434 430 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.020
protein import into nucleus GO:0006606 104 0.020
cellular protein complex assembly GO:0043623 188 0.020
embryo development GO:0009790 123 0.020
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
protein targeting GO:0006605 187 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
regulation of cell division GO:0051302 116 0.020
apoptotic signaling pathway GO:0097190 268 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.019
regulation of meiosis GO:0040020 3 0.019
rna export from nucleus GO:0006405 33 0.019
viral process GO:0016032 146 0.019
endosomal transport GO:0016197 129 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
compound eye development GO:0048749 1 0.018
meiotic chromosome segregation GO:0045132 4 0.018
protein import GO:0017038 130 0.018
nucleoside catabolic process GO:0009164 408 0.018
single organism nuclear import GO:1902593 104 0.018
cellular component morphogenesis GO:0032989 314 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
nuclear import GO:0051170 106 0.018
negative regulation of cell cycle process GO:0010948 121 0.018
nuclear export GO:0051168 69 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
lens development in camera type eye GO:0002088 2 0.017
positive regulation of organelle organization GO:0010638 195 0.017
purine nucleotide catabolic process GO:0006195 405 0.016
trna metabolic process GO:0006399 35 0.016
single organism membrane organization GO:0044802 268 0.016
endomembrane system organization GO:0010256 196 0.016
positive regulation of developmental process GO:0051094 314 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
tissue regeneration GO:0042246 3 0.016
endocytosis GO:0006897 159 0.016
purine containing compound catabolic process GO:0072523 411 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
response to oxygen containing compound GO:1901700 369 0.015
nuclear transport GO:0051169 179 0.015
immune response GO:0006955 307 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
reproductive process GO:0022414 106 0.015
Worm Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
methylation GO:0032259 106 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
cell cycle checkpoint GO:0000075 117 0.014
ras protein signal transduction GO:0007265 73 0.014
oocyte development GO:0048599 1 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
mrna transport GO:0051028 30 0.014
cell projection organization GO:0030030 252 0.014
response to growth factor GO:0070848 205 0.014
negative regulation of cell cycle GO:0045786 193 0.013
actin cytoskeleton organization GO:0030036 207 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
membrane organization GO:0061024 292 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
ribonucleoprotein complex assembly GO:0022618 78 0.013
regulation of viral process GO:0050792 103 0.013
nucleotide catabolic process GO:0009166 408 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of actin filament based process GO:0032970 141 0.012
central nervous system development GO:0007417 123 0.012
Fly
nitrogen compound transport GO:0071705 191 0.012
regulation of protein targeting GO:1903533 91 0.012
chromatin organization GO:0006325 351 0.012
response to radiation GO:0009314 151 0.012
peptidyl serine modification GO:0018209 106 0.012
regulation of cell cycle GO:0051726 393 0.012
reproduction GO:0000003 63 0.012
Worm Fly
cell cycle phase transition GO:0044770 173 0.012
regulation of protein complex assembly GO:0043254 147 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
positive regulation of dna metabolic process GO:0051054 73 0.012
mitotic dna replication checkpoint GO:0033314 2 0.012
cellular amine metabolic process GO:0044106 41 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
Worm
reciprocal dna recombination GO:0035825 4 0.011
regulation of cellular response to stress GO:0080135 244 0.011
protein targeting to nucleus GO:0044744 104 0.011
dna replication GO:0006260 116 0.011
positive regulation of cell death GO:0010942 263 0.011
rna splicing GO:0008380 131 0.011
reproductive structure development GO:0048608 55 0.011
maintenance of location in cell GO:0051651 62 0.011
response to abiotic stimulus GO:0009628 336 0.011
dna recombination GO:0006310 77 0.011
blastoderm segmentation GO:0007350 2 0.011
actin filament based movement GO:0030048 17 0.010
mrna export from nucleus GO:0006406 29 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
rna interference GO:0016246 4 0.010
developmental process involved in reproduction GO:0003006 66 0.010
Fly
gene silencing GO:0016458 49 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010

DROSHA disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.028
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020