Homo sapiens

27 known processes

POLD3

polymerase (DNA-directed), delta 3, accessory subunit

(Aliases: P68,P66,MGC119643,KIAA0039,MGC119642)

POLD3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 198 0.906
dna synthesis involved in dna repair GO:0000731 6 0.880
lagging strand elongation GO:0006273 3 0.824
cellular response to dna damage stimulus GO:0006974 379 0.797
translesion synthesis GO:0019985 8 0.689
vesicle mediated transport GO:0016192 371 0.514
dna biosynthetic process GO:0071897 40 0.469
base excision repair GO:0006284 21 0.463
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.419
determination of adult lifespan GO:0008340 2 0.368
microtubule cytoskeleton organization GO:0000226 176 0.310
mitotic cell cycle GO:0000278 326 0.305
post embryonic development GO:0009791 2 0.264
double strand break repair GO:0006302 101 0.253
dna strand elongation involved in dna replication GO:0006271 3 0.241
blastocyst development GO:0001824 3 0.219
dna replication GO:0006260 116 0.214
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.194
ion homeostasis GO:0050801 230 0.189
response to abiotic stimulus GO:0009628 336 0.180
cell division GO:0051301 168 0.176
nucleus localization GO:0051647 1 0.175
establishment of nucleus localization GO:0040023 1 0.168
dna dependent dna replication GO:0006261 44 0.166
response to uv GO:0009411 73 0.158
fatty acid homeostasis GO:0055089 3 0.150
multicellular organismal aging GO:0010259 3 0.148
positive regulation of hydrolase activity GO:0051345 331 0.126
cell cycle phase transition GO:0044770 173 0.122
meiosis i GO:0007127 4 0.120
recombinational repair GO:0000725 50 0.108
microtubule organizing center organization GO:0031023 62 0.104
organelle fission GO:0048285 149 0.102
nuclear migration GO:0007097 1 0.095
sex differentiation GO:0007548 45 0.092
nucleoside monophosphate catabolic process GO:0009125 159 0.091
rna dependent dna replication GO:0006278 16 0.091
mitotic spindle organization GO:0007052 27 0.090
lipid homeostasis GO:0055088 39 0.089
positive regulation of apoptotic process GO:0043065 246 0.082
nucleoside triphosphate catabolic process GO:0009143 394 0.082
response to activity GO:0014823 0 0.077
chemical homeostasis GO:0048878 306 0.076
microtubule based process GO:0007017 210 0.076
dna strand elongation GO:0022616 5 0.073
mitotic cell cycle process GO:1903047 286 0.073
cell development GO:0048468 328 0.072
positive regulation of transport GO:0051050 336 0.070
embryo development GO:0009790 123 0.070
reproductive process GO:0022414 106 0.068
single organism reproductive process GO:0044702 98 0.068
regulation of cell cycle GO:0051726 393 0.067
nucleoside triphosphate metabolic process GO:0009141 422 0.067
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.066
purine containing compound catabolic process GO:0072523 411 0.066
asymmetric stem cell division GO:0098722 1 0.063
sex determination GO:0007530 3 0.063
rna catabolic process GO:0006401 71 0.063
nucleoside phosphate catabolic process GO:1901292 412 0.063
organophosphate catabolic process GO:0046434 430 0.061
cellular macromolecule catabolic process GO:0044265 380 0.061
nucleotide excision repair GO:0006289 31 0.060
internal protein amino acid acetylation GO:0006475 101 0.059
postreplication repair GO:0006301 12 0.059
purine nucleoside monophosphate metabolic process GO:0009126 186 0.058
glycosyl compound catabolic process GO:1901658 413 0.057
positive regulation of programmed cell death GO:0043068 249 0.054
cellular component morphogenesis GO:0032989 314 0.051
nucleoside monophosphate metabolic process GO:0009123 191 0.050
nervous system development GO:0007399 293 0.050
developmental process involved in reproduction GO:0003006 66 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
tube development GO:0035295 125 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.046
mitotic nuclear division GO:0007067 119 0.045
cellular amino acid metabolic process GO:0006520 116 0.045
endomembrane system organization GO:0010256 196 0.045
nucleotide catabolic process GO:0009166 408 0.044
chromosome segregation GO:0007059 114 0.044
dna catabolic process GO:0006308 49 0.044
nucleoside catabolic process GO:0009164 408 0.043
female gamete generation GO:0007292 2 0.043
enzyme linked receptor protein signaling pathway GO:0007167 303 0.042
cellular protein complex assembly GO:0043623 188 0.042
mitotic cell cycle phase transition GO:0044772 162 0.041
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
cellular macromolecular complex assembly GO:0034622 324 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
purine nucleoside monophosphate catabolic process GO:0009128 158 0.040
cellular response to endogenous stimulus GO:0071495 336 0.040
regulation of intracellular transport GO:0032386 195 0.039
muscle contraction GO:0006936 73 0.039
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.036
cytoplasmic transport GO:0016482 379 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
reproductive system development GO:0061458 56 0.036
regeneration GO:0031099 4 0.035
protein localization to organelle GO:0033365 280 0.035
gonad development GO:0008406 34 0.035
regulation of protein localization GO:0032880 296 0.035
neurogenesis GO:0022008 169 0.034
positive regulation of cell proliferation GO:0008284 301 0.034
cell cycle arrest GO:0007050 71 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
positive regulation of endopeptidase activity GO:0010950 84 0.033
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.033
response to light stimulus GO:0009416 87 0.032
extrinsic apoptotic signaling pathway GO:0097191 119 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.032
dna packaging GO:0006323 77 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.031
dna conformation change GO:0071103 113 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.031
negative regulation of mitotic cell cycle GO:0045930 102 0.031
purine nucleotide catabolic process GO:0006195 405 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.030
covalent chromatin modification GO:0016569 254 0.030
cellular amine metabolic process GO:0044106 41 0.030
histone acetylation GO:0016573 93 0.029
nucleotide biosynthetic process GO:0009165 109 0.029
generation of neurons GO:0048699 152 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
protein targeting GO:0006605 187 0.028
regulation of gene expression epigenetic GO:0040029 73 0.028
negative regulation of cell cycle process GO:0010948 121 0.028
organelle assembly GO:0070925 176 0.028
gene conversion GO:0035822 1 0.027
oxidation reduction process GO:0055114 396 0.027
cellular ketone metabolic process GO:0042180 80 0.027
stem cell division GO:0017145 2 0.027
anion homeostasis GO:0055081 18 0.026
reproductive structure development GO:0048608 55 0.026
double strand break repair via nonhomologous end joining GO:0006303 10 0.026
oogenesis GO:0048477 2 0.026
spermatid development GO:0007286 4 0.026
generation of precursor metabolites and energy GO:0006091 68 0.026
maintenance of location GO:0051235 112 0.026
regulation of establishment of protein localization GO:0070201 242 0.025
amine metabolic process GO:0009308 44 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
protein ubiquitination GO:0016567 314 0.024
atp catabolic process GO:0006200 157 0.024
protein acylation GO:0043543 138 0.024
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.024
establishment of organelle localization GO:0051656 59 0.024
cofactor metabolic process GO:0051186 87 0.024
response to cytokine GO:0034097 232 0.024
positive regulation of catabolic process GO:0009896 310 0.024
protein import GO:0017038 130 0.023
organelle localization GO:0051640 84 0.023
spindle elongation GO:0051231 4 0.023
protein acetylation GO:0006473 116 0.023
immune response GO:0006955 307 0.023
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.023
detection of stimulus GO:0051606 85 0.022
histone modification GO:0016570 251 0.022
embryo development ending in birth or egg hatching GO:0009792 34 0.022
epithelium development GO:0060429 227 0.022
molting cycle GO:0042303 28 0.022
protein targeting to nucleus GO:0044744 104 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
bleb assembly GO:0032060 6 0.021
negative regulation of gene expression epigenetic GO:0045814 19 0.021
myosin filament assembly GO:0031034 2 0.021
response to growth factor GO:0070848 205 0.020
dna replication initiation GO:0006270 6 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.020
cell activation GO:0001775 213 0.020
oocyte development GO:0048599 1 0.020
response to inorganic substance GO:0010035 127 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
carbohydrate metabolic process GO:0005975 207 0.020
dna catabolic process endonucleolytic GO:0000737 37 0.020
cellular lipid catabolic process GO:0044242 65 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
nuclear transport GO:0051169 179 0.020
cellular component assembly involved in morphogenesis GO:0010927 73 0.020
protein import into nucleus GO:0006606 104 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
golgi organization GO:0007030 38 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
actin filament based process GO:0030029 224 0.019
cell fate determination GO:0001709 3 0.019
chromatin modification GO:0016568 298 0.019
regulation of dna methylation GO:0044030 2 0.019
myosin filament organization GO:0031033 2 0.019
secretion GO:0046903 254 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
nitrogen compound transport GO:0071705 191 0.018
endocytosis GO:0006897 159 0.018
positive regulation of protein transport GO:0051222 135 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
atp metabolic process GO:0046034 176 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
regulation of proteolysis GO:0030162 293 0.018
isotype switching GO:0045190 3 0.017
apoptotic signaling pathway GO:0097190 268 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.017
positive regulation of immune system process GO:0002684 283 0.017
cell growth GO:0016049 160 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
response to acid chemical GO:0001101 66 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
intracellular protein transport GO:0006886 270 0.017
humoral immune response GO:0006959 49 0.017
striated muscle contraction GO:0006941 52 0.017
epithelial cell differentiation GO:0030855 141 0.017
ras protein signal transduction GO:0007265 73 0.017
insemination GO:0007320 1 0.016
cardiovascular system development GO:0072358 262 0.016
phospholipid catabolic process GO:0009395 12 0.016
cellular protein catabolic process GO:0044257 261 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
response to transforming growth factor beta GO:0071559 94 0.016
response to other organism GO:0051707 261 0.016
chordate embryonic development GO:0043009 34 0.016
response to biotic stimulus GO:0009607 276 0.016
spindle organization GO:0007051 53 0.016
dna damage checkpoint GO:0000077 68 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
somatic hypermutation of immunoglobulin genes GO:0016446 1 0.016
regulation of peptidase activity GO:0052547 180 0.016
single organism cellular localization GO:1902580 332 0.016
mitotic spindle elongation GO:0000022 4 0.015
cellular component disassembly GO:0022411 92 0.015
response to radiation GO:0009314 151 0.015
striated muscle myosin thick filament assembly GO:0071688 2 0.015
male meiosis GO:0007140 1 0.015
dephosphorylation GO:0016311 209 0.015
mismatch repair GO:0006298 15 0.015
lymphocyte activation GO:0046649 133 0.015
glycosylation GO:0070085 71 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of cellular response to stress GO:0080135 244 0.014
maintenance of dna repeat elements GO:0043570 4 0.014
regulation of cell cycle process GO:0010564 266 0.014
mitotic cell cycle checkpoint GO:0007093 68 0.014
response to bacterium GO:0009617 144 0.014
macromolecule glycosylation GO:0043413 63 0.014
protein localization to nucleus GO:0034504 136 0.014
response to dietary excess GO:0002021 2 0.014
system process GO:0003008 349 0.014
regulation of dephosphorylation GO:0035303 96 0.014
response to organic cyclic compound GO:0014070 204 0.014
neural tube closure GO:0001843 3 0.014
cell cycle checkpoint GO:0000075 117 0.014
spermatid differentiation GO:0048515 4 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
coenzyme metabolic process GO:0006732 65 0.014
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.014
cellular amide metabolic process GO:0043603 69 0.014
negative regulation of chromatin silencing GO:0031936 4 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
response to nutrient levels GO:0031667 81 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
response to hormone GO:0009725 175 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
organ morphogenesis GO:0009887 147 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
response to external biotic stimulus GO:0043207 261 0.014
modification dependent protein catabolic process GO:0019941 209 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
internal peptidyl lysine acetylation GO:0018393 97 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
nuclear division GO:0000280 128 0.013
dna recombination GO:0006310 77 0.013
aging GO:0007568 66 0.013
growth GO:0040007 202 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
single organism membrane organization GO:0044802 268 0.013
somatic muscle development GO:0007525 1 0.013
cell cycle dna replication GO:0044786 11 0.013
negative regulation of growth GO:0045926 97 0.013
response to virus GO:0009615 126 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
interspecies interaction between organisms GO:0044419 156 0.013
protein maturation GO:0051604 233 0.013
alpha amino acid metabolic process GO:1901605 72 0.013
anatomical structure homeostasis GO:0060249 100 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
tissue regeneration GO:0042246 3 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
viral life cycle GO:0019058 132 0.012
wnt signaling pathway GO:0016055 156 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
retina layer formation GO:0010842 3 0.012
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.012
positive regulation of cell death GO:0010942 263 0.012
activation of cysteine type endopeptidase activity GO:0097202 57 0.012
multi organism reproductive process GO:0044703 54 0.012
cell activation involved in immune response GO:0002263 30 0.012
dna templated transcription elongation GO:0006354 25 0.012
cell morphogenesis GO:0000902 296 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
development of primary male sexual characteristics GO:0046546 23 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
muscle system process GO:0003012 81 0.012
oocyte differentiation GO:0009994 2 0.012
positive regulation of immune response GO:0050778 159 0.012
positive regulation of nuclease activity GO:0032075 5 0.012
reproduction GO:0000003 63 0.011
cell projection organization GO:0030030 252 0.011
membrane organization GO:0061024 292 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
negative regulation of cell cycle phase transition GO:1901988 89 0.011
dna unwinding involved in dna replication GO:0006268 2 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
lens development in camera type eye GO:0002088 2 0.011
response to testosterone GO:0033574 1 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
centrosome organization GO:0051297 58 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
development of primary sexual characteristics GO:0045137 35 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of viral genome replication GO:0045069 48 0.011
inorganic anion transport GO:0015698 60 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
response to oxygen containing compound GO:1901700 369 0.011
nuclear import GO:0051170 106 0.011
lipid localization GO:0010876 106 0.011
immune effector process GO:0002252 159 0.011
cell cell signaling GO:0007267 155 0.011
protein processing GO:0016485 226 0.011
regulation of cellular component movement GO:0051270 334 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
somatic stem cell maintenance GO:0035019 4 0.011
response to caffeine GO:0031000 3 0.011
protein catabolic process GO:0030163 325 0.010
locomotory behavior GO:0007626 1 0.010
meiotic chromosome separation GO:0051307 3 0.010
peripheral nervous system development GO:0007422 2 0.010
glycoprotein metabolic process GO:0009100 110 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
secretion by cell GO:0032940 226 0.010
somatic diversification of immune receptors via somatic mutation GO:0002566 1 0.010
interstrand cross link repair GO:0036297 3 0.010
double strand break repair via single strand annealing GO:0045002 4 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010
regulation of dna repair GO:0006282 47 0.010
sexual reproduction GO:0019953 37 0.010
mapk cascade GO:0000165 288 0.010

POLD3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.358
disease of cellular proliferation DOID:14566 174 0.358
organ system cancer DOID:0050686 164 0.358
disease of metabolism DOID:0014667 295 0.312
gastrointestinal system cancer DOID:3119 52 0.203
large intestine cancer DOID:5672 29 0.107
intestinal cancer DOID:10155 29 0.107
colorectal cancer DOID:9256 29 0.107
inherited metabolic disorder DOID:655 242 0.103
reproductive organ cancer DOID:193 23 0.012
carbohydrate metabolic disorder DOID:2978 55 0.012
congenital disorder of glycosylation DOID:5212 26 0.012
nervous system disease DOID:863 431 0.011
neuropathy DOID:870 52 0.011