Homo sapiens

25 known processes

CHRNA2

cholinergic receptor, nicotinic, alpha 2 (neuronal)

CHRNA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
micturition GO:0060073 3 0.420
Human
cation transport GO:0006812 331 0.146
synaptic transmission involved in micturition GO:0060084 2 0.135
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.106
Human
cellular homeostasis GO:0019725 196 0.096
Human
metal ion homeostasis GO:0055065 169 0.078
Human
transmembrane transport GO:0055085 399 0.078
positive regulation of transport GO:0051050 336 0.076
metal ion transport GO:0030001 272 0.074
Human
cellular cation homeostasis GO:0030003 163 0.074
Human
regulation of kinase activity GO:0043549 314 0.070
Human
ion transmembrane transport GO:0034220 338 0.067
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.067
Human
inorganic ion transmembrane transport GO:0098660 231 0.061
Human
cellular ketone metabolic process GO:0042180 80 0.059
cellular amino acid metabolic process GO:0006520 116 0.057
lipid metabolic process GO:0006629 381 0.053
regulation of ion transport GO:0043269 189 0.053
Human
mapk cascade GO:0000165 288 0.051
Human
regulation of cellular amine metabolic process GO:0033238 11 0.051
chemical homeostasis GO:0048878 306 0.051
Human
regulation of protein kinase activity GO:0045859 289 0.050
Human
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.049
postsynaptic membrane organization GO:0001941 2 0.049
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.048
regulation of mapk cascade GO:0043408 262 0.047
Human
regulation of ion transmembrane transport GO:0034765 132 0.047
Human
amine metabolic process GO:0009308 44 0.046
locomotory behavior GO:0007626 1 0.046
cellular amine metabolic process GO:0044106 41 0.046
muscle system process GO:0003012 81 0.045
Human
system process GO:0003008 349 0.045
Human
cellular calcium ion homeostasis GO:0006874 117 0.044
Human
multicellular organismal aging GO:0010259 3 0.043
positive regulation of phosphatidylinositol biosynthetic process GO:0010513 3 0.043
organophosphate catabolic process GO:0046434 430 0.043
cellular divalent inorganic cation homeostasis GO:0072503 128 0.042
Human
muscle contraction GO:0006936 73 0.041
Human
determination of adult lifespan GO:0008340 2 0.040
signal transduction by phosphorylation GO:0023014 297 0.039
Human
regulation of secretion GO:0051046 194 0.039
ion homeostasis GO:0050801 230 0.039
Human
immune response GO:0006955 307 0.039
cytosolic calcium ion homeostasis GO:0051480 89 0.038
Human
divalent inorganic cation homeostasis GO:0072507 136 0.038
Human
cellular metal ion homeostasis GO:0006875 146 0.038
Human
regulation of transferase activity GO:0051338 355 0.038
Human
post embryonic development GO:0009791 2 0.037
synaptic transmission cholinergic GO:0007271 2 0.036
Human Fly
positive regulation of phosphorylation GO:0042327 394 0.036
Human
membrane organization GO:0061024 292 0.036
Human
inorganic cation transmembrane transport GO:0098662 194 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
cellular ion homeostasis GO:0006873 168 0.035
Human
memory GO:0007613 3 0.035
Human
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.034
Human
cellular chemical homeostasis GO:0055082 180 0.034
Human
positive regulation of intestinal epithelial structure maintenance GO:0060731 1 0.034
single organism membrane organization GO:0044802 268 0.034
Human
regulation of secretion by cell GO:1903530 177 0.034
cation transmembrane transport GO:0098655 238 0.033
calcium ion transport GO:0006816 147 0.033
Human
nitrogen compound transport GO:0071705 191 0.033
positive regulation of transferase activity GO:0051347 227 0.033
Human
regulation of transmembrane transport GO:0034762 139 0.033
Human
positive regulation of developmental process GO:0051094 314 0.032
Human
female gamete generation GO:0007292 2 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
positive regulation of protein kinase activity GO:0045860 190 0.032
Human
protein oligomerization GO:0051259 173 0.031
cellular lipid metabolic process GO:0044255 303 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
neuromuscular junction development GO:0007528 3 0.029
Human
organic hydroxy compound transport GO:0015850 63 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
anion transport GO:0006820 161 0.029
Human
glycerolipid metabolic process GO:0046486 107 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
mating GO:0007618 1 0.028
activation of protein kinase activity GO:0032147 90 0.028
Human
sensory perception GO:0007600 103 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
purine containing compound catabolic process GO:0072523 411 0.028
regulation of cytokine production GO:0001817 232 0.027
Human
vesicle mediated transport GO:0016192 371 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
regulation of transmembrane transporter activity GO:0022898 74 0.027
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.027
response to oxygen containing compound GO:1901700 369 0.027
behavior GO:0007610 112 0.026
Human
secretion GO:0046903 254 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
oogenesis GO:0048477 2 0.026
response to abiotic stimulus GO:0009628 336 0.026
Human
purine nucleoside catabolic process GO:0006152 398 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
response to nitrogen compound GO:1901698 184 0.026
Human
angiogenesis GO:0001525 147 0.026
Human
positive regulation of protein phosphorylation GO:0001934 313 0.025
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
nucleotide catabolic process GO:0009166 408 0.025
purine nucleotide biosynthetic process GO:0006164 84 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
Human
glycosyl compound catabolic process GO:1901658 413 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
negative regulation of cell death GO:0060548 345 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
neurological system process GO:0050877 163 0.024
Human
positive regulation of ion transport GO:0043270 87 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
nucleoside catabolic process GO:0009164 408 0.023
carbohydrate metabolic process GO:0005975 207 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
sensory perception of pain GO:0019233 4 0.023
divalent metal ion transport GO:0070838 152 0.023
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
Human
ras protein signal transduction GO:0007265 73 0.023
positive regulation of kinase activity GO:0033674 204 0.023
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.023
visual learning GO:0008542 1 0.023
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
innate immune response GO:0045087 178 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
dephosphorylation GO:0016311 209 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
regulation of metal ion transport GO:0010959 120 0.022
protein catabolic process GO:0030163 325 0.021
positive regulation of secretion GO:0051047 116 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
nucleotide biosynthetic process GO:0009165 109 0.021
regeneration GO:0031099 4 0.021
camp metabolic process GO:0046058 61 0.021
cytokine production GO:0001816 247 0.020
Human
guanosine containing compound metabolic process GO:1901068 244 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
Human
single organism cellular localization GO:1902580 332 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
secretion by cell GO:0032940 226 0.020
cation homeostasis GO:0055080 189 0.020
Human
striated muscle contraction GO:0006941 52 0.020
Human
response to hypoxia GO:0001666 96 0.020
Human
maintenance of location GO:0051235 112 0.020
response to hormone GO:0009725 175 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
negative regulation of transport GO:0051051 176 0.019
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
cardiovascular system development GO:0072358 262 0.019
Human
associative learning GO:0008306 1 0.019
Human
response to inorganic substance GO:0010035 127 0.019
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.019
morphogenesis of embryonic epithelium GO:0016331 4 0.019
urate transport GO:0015747 3 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
Human
single organism carbohydrate metabolic process GO:0044723 193 0.019
monovalent inorganic cation transport GO:0015672 128 0.019
cytoplasmic transport GO:0016482 379 0.018
response to oxygen levels GO:0070482 100 0.018
Human
regulation of cellular component movement GO:0051270 334 0.018
divalent inorganic cation transport GO:0072511 158 0.018
Human
regulation of ion transmembrane transporter activity GO:0032412 72 0.018
Human
apoptotic signaling pathway GO:0097190 268 0.018
blood vessel morphogenesis GO:0048514 162 0.018
Human
response to metal ion GO:0010038 84 0.018
Human
blood vessel development GO:0001568 172 0.018
Human
nervous system development GO:0007399 293 0.018
Human
nucleoside phosphate catabolic process GO:1901292 412 0.017
circulatory system development GO:0072359 262 0.017
Human
regulation of nucleoside metabolic process GO:0009118 209 0.017
organic anion transport GO:0015711 103 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
response to organonitrogen compound GO:0010243 156 0.017
Human
organic acid transport GO:0015849 65 0.017
alpha ketoglutarate transport GO:0015742 1 0.017
homeostasis of number of cells in a free living population GO:0048874 1 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.017
regulation of protein localization GO:0032880 296 0.017
muscle cell cellular homeostasis GO:0046716 3 0.017
Human
regulation of cellular component biogenesis GO:0044087 281 0.017
cell projection organization GO:0030030 252 0.017
regulation of cell cycle GO:0051726 393 0.016
adult locomotory behavior GO:0008344 1 0.016
regulation of angiogenesis GO:0045765 92 0.016
Human
glycoprotein metabolic process GO:0009100 110 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
regulation of vasculature development GO:1901342 97 0.016
Human
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
regulation of response to external stimulus GO:0032101 222 0.016
protein localization to membrane GO:0072657 160 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
visual behavior GO:0007632 2 0.016
Human
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.016
regulation of cellular response to stress GO:0080135 244 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
gtp catabolic process GO:0006184 237 0.016
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 0.015
vasculature development GO:0001944 181 0.015
Human
regulation of vesicle mediated transport GO:0060627 130 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
covalent chromatin modification GO:0016569 254 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cyclic purine nucleotide metabolic process GO:0052652 60 0.015
cell adhesion GO:0007155 325 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
regulation of membrane potential GO:0042391 95 0.015
Human
protein processing GO:0016485 226 0.015
circadian behavior GO:0048512 2 0.015
regulation of immune response GO:0050776 201 0.015
lipid biosynthetic process GO:0008610 177 0.015
cellular protein catabolic process GO:0044257 261 0.015
response to decreased oxygen levels GO:0036293 96 0.015
Human
catecholamine secretion GO:0050432 1 0.015
response to radiation GO:0009314 151 0.015
Human
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 2 0.014
regulation of calcium ion transport GO:0051924 79 0.014
regulation of map kinase activity GO:0043405 108 0.014
Human
anion transmembrane transport GO:0098656 76 0.014
Human
anatomical structure homeostasis GO:0060249 100 0.014
Human
positive regulation of map kinase activity GO:0043406 80 0.014
Human
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of intracellular transport GO:0032386 195 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
positive regulation of synaptic transmission GO:0050806 4 0.014
regulation of proteolysis GO:0030162 293 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
response to organic cyclic compound GO:0014070 204 0.014
Human
response to disaccharide GO:0034285 1 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of erk1 and erk2 cascade GO:0070372 99 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
biological adhesion GO:0022610 331 0.014
rhythmic behavior GO:0007622 2 0.014
dna repair GO:0006281 198 0.014
Human
regulation of camp biosynthetic process GO:0030817 45 0.014
positive regulation of cell motility GO:2000147 177 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
small molecule biosynthetic process GO:0044283 157 0.013
gtp metabolic process GO:0046039 239 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
protein maturation GO:0051604 233 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
negative regulation of protein modification process GO:0031400 200 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
positive regulation of catabolic process GO:0009896 310 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
serotonin transport GO:0006837 3 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of cell motility GO:2000145 299 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
phospholipid metabolic process GO:0006644 99 0.013
oocyte differentiation GO:0009994 2 0.013
blastoderm segmentation GO:0007350 2 0.013
oocyte development GO:0048599 1 0.013
negative regulation of transferase activity GO:0051348 124 0.013
protein localization to organelle GO:0033365 280 0.013
organic acid biosynthetic process GO:0016053 97 0.013
sequestering of calcium ion GO:0051208 17 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
Human
regulation of synaptic plasticity GO:0048167 3 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.012
regulation of cell projection organization GO:0031344 107 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
immune effector process GO:0002252 159 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
cell development GO:0048468 328 0.012
Human
endocytosis GO:0006897 159 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
ribonucleotide biosynthetic process GO:0009260 81 0.012
neuroblast proliferation GO:0007405 4 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.012
Human
response to axon injury GO:0048678 1 0.012
cell division GO:0051301 168 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
cell cell signaling GO:0007267 155 0.012
growth GO:0040007 202 0.012
Human
carboxylic acid transport GO:0046942 63 0.012
positive regulation of angiogenesis GO:0045766 51 0.012
Human
negative regulation of apoptotic process GO:0043066 316 0.012
lipid localization GO:0010876 106 0.012
defense response GO:0006952 315 0.012
receptor metabolic process GO:0043112 81 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
skeletal muscle tissue growth GO:0048630 2 0.012
Human
blood circulation GO:0008015 113 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
microtubule based process GO:0007017 210 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
response to oxidative stress GO:0006979 121 0.012
Human
regulation of homeostatic process GO:0032844 121 0.012
oxidation reduction process GO:0055114 396 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
Human
regulation of cell cycle process GO:0010564 266 0.011
response to lipid GO:0033993 206 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
Human
glycoprotein biosynthetic process GO:0009101 91 0.011
mitotic cell cycle GO:0000278 326 0.011
leukocyte migration GO:0050900 107 0.011
anterior posterior axis specification GO:0009948 2 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
erk1 and erk2 cascade GO:0070371 104 0.011
receptor transactivation GO:0035624 4 0.011
histone modification GO:0016570 251 0.011
intracellular protein transport GO:0006886 270 0.011
positive regulation of organic acid transport GO:0032892 3 0.011
response to other organism GO:0051707 261 0.011
spermatid differentiation GO:0048515 4 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
carnitine transmembrane transport GO:1902603 3 0.011
atp metabolic process GO:0046034 176 0.011
immune response in mucosal associated lymphoid tissue GO:0002386 1 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
rho protein signal transduction GO:0007266 26 0.011
protein targeting GO:0006605 187 0.011
hindbrain development GO:0030902 3 0.011
actin filament based process GO:0030029 224 0.011
cell activation GO:0001775 213 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
positive regulation of immune system process GO:0002684 283 0.011
cell type specific apoptotic process GO:0097285 125 0.011
tripartite regional subdivision GO:0007351 2 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
phospholipase c activating adrenergic receptor signaling pathway GO:0071882 1 0.011
calcium ion homeostasis GO:0055074 122 0.011
Human
cellular response to nitrogen compound GO:1901699 144 0.011
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.011
positive regulation of digestive system process GO:0060456 2 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
glycerolipid biosynthetic process GO:0045017 51 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
segmentation GO:0035282 4 0.011
regulation of protein processing GO:0070613 150 0.011
chemotaxis GO:0006935 157 0.011
positive regulation of cell migration GO:0030335 172 0.011
regulation of camp metabolic process GO:0030814 52 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
organelle assembly GO:0070925 176 0.010
long term memory GO:0007616 2 0.010
circulatory system process GO:0003013 113 0.010
activation of mapk activity GO:0000187 45 0.010
Human
cellular carbohydrate metabolic process GO:0044262 84 0.010
camp biosynthetic process GO:0006171 47 0.010
response to mercury ion GO:0046689 4 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
spermatid development GO:0007286 4 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
regulation of meiosis GO:0040020 3 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of cell differentiation GO:0045595 393 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010

CHRNA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.035
sensory system disease DOID:0050155 203 0.028
nervous system disease DOID:863 431 0.028
disease of metabolism DOID:0014667 295 0.024
cardiovascular system disease DOID:1287 106 0.018
disease of cellular proliferation DOID:14566 174 0.016
muscular disease DOID:0080000 114 0.016
muscle tissue disease DOID:66 113 0.016
myopathy DOID:423 104 0.015
cancer DOID:162 167 0.015
central nervous system disease DOID:331 186 0.014
organ system cancer DOID:0050686 164 0.014
eye and adnexa disease DOID:1492 150 0.014
immune system disease DOID:2914 155 0.014
retinal disease DOID:5679 118 0.014
eye disease DOID:5614 149 0.014
acquired metabolic disease DOID:0060158 58 0.013
heart disease DOID:114 68 0.012
kidney disease DOID:557 36 0.012
urinary system disease DOID:18 40 0.012
night blindness DOID:8499 10 0.012
congenital stationary night blindness DOID:0050534 8 0.012
neurodegenerative disease DOID:1289 102 0.012
retinal degeneration DOID:8466 89 0.011
cardiomyopathy DOID:0050700 50 0.011
auditory system disease DOID:2742 53 0.011
bone disease DOID:0080001 88 0.010
connective tissue disease DOID:65 109 0.010