Homo sapiens

130 known processes

GLI3

GLI family zinc finger 3

(Aliases: GCPS,GLI3FL,PAP-A,PAPA1,PAPA,PAPB,PPDIV,ACLS,PHS,GLI3-190)

GLI3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.345
Mouse
organ morphogenesis GO:0009887 147 0.317
Mouse Fly
smoothened signaling pathway GO:0007224 14 0.289
Human Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.288
Mouse Fly
post embryonic development GO:0009791 2 0.283
morphogenesis of embryonic epithelium GO:0016331 4 0.272
spinal cord dorsal ventral patterning GO:0021513 2 0.261
Mouse
cell morphogenesis GO:0000902 296 0.228
Mouse Fly
cellular component morphogenesis GO:0032989 314 0.225
Mouse Fly
cell projection organization GO:0030030 252 0.225
Mouse Fly
nervous system development GO:0007399 293 0.209
Mouse Fly
negative regulation of developmental process GO:0051093 247 0.206
Mouse
regulation of cell differentiation GO:0045595 393 0.190
Mouse Fly
cardiovascular system development GO:0072358 262 0.175
Mouse Fly
circulatory system development GO:0072359 262 0.149
Mouse Fly
embryonic morphogenesis GO:0048598 85 0.145
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.142
enzyme linked receptor protein signaling pathway GO:0007167 303 0.141
spinal cord development GO:0021510 4 0.137
Mouse
embryonic epithelial tube formation GO:0001838 4 0.136
cell development GO:0048468 328 0.135
Mouse Fly
epithelium development GO:0060429 227 0.128
Human Mouse Fly
cell projection morphogenesis GO:0048858 129 0.114
Mouse Fly
central nervous system development GO:0007417 123 0.114
Mouse
cellular ketone metabolic process GO:0042180 80 0.114
cell differentiation in spinal cord GO:0021515 1 0.111
Mouse
amine metabolic process GO:0009308 44 0.107
negative regulation of multicellular organismal process GO:0051241 317 0.105
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.105
heart formation GO:0060914 2 0.104
Fly
organ formation GO:0048645 3 0.102
Mouse Fly
cell adhesion GO:0007155 325 0.100
neural tube formation GO:0001841 3 0.100
tissue morphogenesis GO:0048729 96 0.098
Mouse
brain development GO:0007420 97 0.097
Mouse
neuron differentiation GO:0030182 138 0.095
Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.094
Mouse Fly
cellular amine metabolic process GO:0044106 41 0.093
head development GO:0060322 108 0.092
Mouse
cellular amino acid metabolic process GO:0006520 116 0.092
taxis GO:0042330 157 0.090
Mouse
primary neural tube formation GO:0014020 3 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.088
system process GO:0003008 349 0.087
regulation of cellular amino acid metabolic process GO:0006521 6 0.084
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.083
hindbrain development GO:0030902 3 0.083
positive regulation of developmental process GO:0051094 314 0.081
Mouse Fly
ras protein signal transduction GO:0007265 73 0.079
regulation of locomotion GO:0040012 329 0.078
small gtpase mediated signal transduction GO:0007264 78 0.077
cell part morphogenesis GO:0032990 137 0.077
Mouse Fly
pituitary gland development GO:0021983 2 0.076
negative regulation of protein metabolic process GO:0051248 391 0.074
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.072
chemotaxis GO:0006935 157 0.072
Mouse
cranial nerve development GO:0021545 4 0.071
Mouse
positive regulation of smoothened signaling pathway GO:0045880 4 0.071
Human
cellular response to growth factor stimulus GO:0071363 197 0.070
tube morphogenesis GO:0035239 95 0.070
Mouse
neurogenesis GO:0022008 169 0.069
Mouse Fly
regulation of cell development GO:0060284 161 0.068
Mouse
retinal ganglion cell axon guidance GO:0031290 2 0.068
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.067
neuron projection development GO:0031175 106 0.067
Mouse Fly
cilium morphogenesis GO:0060271 75 0.065
ossification GO:0001503 121 0.065
Human Mouse
blastoderm segmentation GO:0007350 2 0.065
Fly
motor neuron axon guidance GO:0008045 2 0.063
positive regulation of cellular amine metabolic process GO:0033240 7 0.060
cilium assembly GO:0042384 63 0.060
vasculature development GO:0001944 181 0.059
Mouse
female gamete generation GO:0007292 2 0.058
Fly
pattern specification involved in kidney development GO:0061004 1 0.057
anterior posterior axis specification GO:0009948 2 0.057
skeletal system development GO:0001501 79 0.056
Mouse
epithelial tube morphogenesis GO:0060562 38 0.056
Mouse
negative regulation of smoothened signaling pathway GO:0045879 3 0.055
Mouse
regulation of cell migration GO:0030334 289 0.055
ventral spinal cord interneuron differentiation GO:0021514 1 0.055
Mouse
purine nucleotide catabolic process GO:0006195 405 0.055
multicellular organismal aging GO:0010259 3 0.055
biological adhesion GO:0022610 331 0.054
response to growth factor GO:0070848 205 0.054
positive regulation of cellular component organization GO:0051130 376 0.054
negative regulation of protein modification process GO:0031400 200 0.053
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.053
cellular response to endogenous stimulus GO:0071495 336 0.052
negative regulation of cellular protein metabolic process GO:0032269 353 0.052
cilium organization GO:0044782 68 0.052
regulation of cellular component movement GO:0051270 334 0.051
segmentation GO:0035282 4 0.051
Fly
morphogenesis of an epithelium GO:0002009 60 0.050
Mouse
negative regulation of catalytic activity GO:0043086 335 0.050
epithelial cell migration GO:0010631 119 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
organophosphate catabolic process GO:0046434 430 0.050
tissue migration GO:0090130 119 0.049
neuron development GO:0048666 113 0.049
Mouse Fly
heart development GO:0007507 95 0.049
Mouse Fly
positive regulation of locomotion GO:0040017 186 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
peripheral nervous system development GO:0007422 2 0.048
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
negative regulation of cell migration GO:0030336 102 0.048
negative regulation of cell differentiation GO:0045596 171 0.048
Mouse
heart morphogenesis GO:0003007 48 0.048
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
regulation of wnt signaling pathway GO:0030111 123 0.047
ameboidal type cell migration GO:0001667 135 0.047
determination of adult lifespan GO:0008340 2 0.047
positive regulation of cell proliferation GO:0008284 301 0.047
Human Mouse
skeletal system morphogenesis GO:0048705 24 0.046
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.046
tube closure GO:0060606 3 0.046
cell projection assembly GO:0030031 126 0.045
tube development GO:0035295 125 0.044
Mouse
negative regulation of cell proliferation GO:0008285 228 0.044
Mouse
guanosine containing compound metabolic process GO:1901068 244 0.044
purine nucleoside catabolic process GO:0006152 398 0.043
somatic stem cell maintenance GO:0035019 4 0.043
positive regulation of cell differentiation GO:0045597 211 0.043
Mouse Fly
growth GO:0040007 202 0.043
Mouse
locomotory behavior GO:0007626 1 0.043
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
regulation of protein localization GO:0032880 296 0.043
Mouse
regulation of cell motility GO:2000145 299 0.043
regulation of gtpase activity GO:0043087 180 0.043
ribonucleotide catabolic process GO:0009261 405 0.042
protein catabolic process GO:0030163 325 0.042
neural tube closure GO:0001843 3 0.042
pattern specification process GO:0007389 43 0.042
Mouse Fly
forebrain regionalization GO:0021871 3 0.042
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.042
blood vessel development GO:0001568 172 0.042
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
single organism cell adhesion GO:0098602 179 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
nucleoside triphosphate metabolic process GO:0009141 422 0.041
epithelium migration GO:0090132 119 0.040
positive regulation of hydrolase activity GO:0051345 331 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.039
renal system pattern specification GO:0072048 1 0.039
positive regulation of nucleotide metabolic process GO:0045981 230 0.039
dephosphorylation GO:0016311 209 0.039
stem cell development GO:0048864 69 0.039
nucleotide catabolic process GO:0009166 408 0.039
regulation of epithelial cell migration GO:0010632 93 0.038
regulation of cell cycle GO:0051726 393 0.038
Fly
negative regulation of cellular component organization GO:0051129 235 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
inner ear morphogenesis GO:0042472 4 0.038
forelimb morphogenesis GO:0035136 4 0.038
nerve development GO:0021675 4 0.037
Mouse
positive regulation of phosphorylation GO:0042327 394 0.037
response to abiotic stimulus GO:0009628 336 0.037
embryonic forelimb morphogenesis GO:0035115 4 0.037
rho protein signal transduction GO:0007266 26 0.037
regionalization GO:0003002 29 0.037
Mouse Fly
intracellular protein transport GO:0006886 270 0.037
Mouse
oogenesis GO:0048477 2 0.036
Fly
response to oxygen containing compound GO:1901700 369 0.036
positive regulation of immune system process GO:0002684 283 0.036
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.036
nucleoside catabolic process GO:0009164 408 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
negative regulation of embryonic development GO:0045992 4 0.036
generation of neurons GO:0048699 152 0.036
Mouse Fly
negative regulation of locomotion GO:0040013 118 0.036
wound healing GO:0042060 115 0.036
gland development GO:0048732 48 0.035
Mouse
regulation of gtp catabolic process GO:0033124 180 0.035
regulation of cell adhesion GO:0030155 166 0.035
negative regulation of apoptotic process GO:0043066 316 0.035
Mouse
embryo development GO:0009790 123 0.035
Mouse Worm Fly
urogenital system development GO:0001655 65 0.034
Mouse
purine containing compound catabolic process GO:0072523 411 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
mitotic cell cycle GO:0000278 326 0.034
Worm Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
regulation of purine nucleotide catabolic process GO:0033121 205 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
gtp catabolic process GO:0006184 237 0.034
muscle cell fate commitment GO:0042693 4 0.033
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.033
ventral spinal cord development GO:0021517 1 0.033
Mouse
glycosyl compound catabolic process GO:1901658 413 0.033
guanosine containing compound catabolic process GO:1901069 239 0.033
sensory organ morphogenesis GO:0090596 21 0.033
Mouse Fly
cell substrate adhesion GO:0031589 132 0.033
gtp metabolic process GO:0046039 239 0.033
positive regulation of catabolic process GO:0009896 310 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
negative regulation of cellular component movement GO:0051271 106 0.032
immune response GO:0006955 307 0.032
negative regulation of wnt signaling pathway GO:0030178 69 0.032
blood vessel morphogenesis GO:0048514 162 0.032
response to wounding GO:0009611 168 0.032
organelle assembly GO:0070925 176 0.032
wnt signaling pathway GO:0016055 156 0.031
regulation of canonical wnt signaling pathway GO:0060828 88 0.031
regulation of intracellular protein transport GO:0033157 123 0.031
Mouse
chromatin modification GO:0016568 298 0.031
renal system development GO:0072001 63 0.031
Mouse
positive regulation of cell development GO:0010720 92 0.031
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.030
negative regulation of cell motility GO:2000146 104 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
cellular macromolecular complex assembly GO:0034622 324 0.030
chromatin organization GO:0006325 351 0.030
membrane organization GO:0061024 292 0.030
positive regulation of nucleoside metabolic process GO:0045979 186 0.030
regulation of nervous system development GO:0051960 88 0.030
Mouse
regeneration GO:0031099 4 0.030
metencephalon development GO:0022037 2 0.029
lipid metabolic process GO:0006629 381 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
Mouse
neuron projection morphogenesis GO:0048812 50 0.029
Mouse Fly
protein processing GO:0016485 226 0.029
Mouse
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
regulation of cell cycle process GO:0010564 266 0.029
Fly
negative regulation of programmed cell death GO:0043069 321 0.029
Mouse
glial cell migration GO:0008347 4 0.029
sex determination GO:0007530 3 0.029
Worm
luteolysis GO:0001554 3 0.029
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.028
mapk cascade GO:0000165 288 0.028
protein import GO:0017038 130 0.028
Mouse
angiogenesis GO:0001525 147 0.028
oocyte differentiation GO:0009994 2 0.028
maintenance of location GO:0051235 112 0.028
cerebral cortex cell migration GO:0021795 3 0.028
Mouse
negative regulation of organelle organization GO:0010639 126 0.028
single organism cellular localization GO:1902580 332 0.028
Mouse
midgut development GO:0007494 1 0.028
negative regulation of hydrolase activity GO:0051346 182 0.028
embryonic organ development GO:0048568 36 0.028
Mouse
neurological system process GO:0050877 163 0.028
cartilage condensation GO:0001502 1 0.027
endochondral bone morphogenesis GO:0060350 3 0.027
oocyte development GO:0048599 1 0.027
forebrain development GO:0030900 26 0.027
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.027
organonitrogen compound biosynthetic process GO:1901566 200 0.027
compound eye development GO:0048749 1 0.027
cellular component assembly involved in morphogenesis GO:0010927 73 0.027
regulation of small gtpase mediated signal transduction GO:0051056 156 0.027
negative regulation of gliogenesis GO:0014014 3 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
regulation of nucleotide catabolic process GO:0030811 205 0.026
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.026
positive regulation of gtpase activity GO:0043547 166 0.026
forebrain neuron differentiation GO:0021879 3 0.026
cytokine production GO:0001816 247 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
epidermis morphogenesis GO:0048730 3 0.026
regulation of mapk cascade GO:0043408 262 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
protein localization to organelle GO:0033365 280 0.026
Mouse
stem cell differentiation GO:0048863 93 0.026
regulation of ossification GO:0030278 58 0.026
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.026
lens development in camera type eye GO:0002088 2 0.026
negative regulation of cell death GO:0060548 345 0.026
Mouse
protein maturation GO:0051604 233 0.026
Mouse
regulation of protein transport GO:0051223 213 0.025
Mouse
cell fate determination GO:0001709 3 0.025
transmembrane transport GO:0055085 399 0.025
regulation of proteolysis GO:0030162 293 0.025
positive regulation of cellular component movement GO:0051272 181 0.025
cytoplasmic transport GO:0016482 379 0.025
Mouse
kidney development GO:0001822 53 0.025
Mouse
limbic system development GO:0021761 3 0.025
Mouse
single organismal cell cell adhesion GO:0016337 148 0.025
cellular protein catabolic process GO:0044257 261 0.025
kidney epithelium development GO:0072073 25 0.025
Mouse
positive regulation of gtp catabolic process GO:0033126 166 0.025
regulation of protein targeting GO:1903533 91 0.025
Mouse
defense response GO:0006952 315 0.025
regulation of intracellular transport GO:0032386 195 0.024
Mouse
cell aggregation GO:0098743 1 0.024
microtubule based process GO:0007017 210 0.024
Worm
regulation of ras protein signal transduction GO:0046578 155 0.024
regulation of axon guidance GO:1902667 3 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
eye development GO:0001654 42 0.024
Mouse Fly
brain morphogenesis GO:0048854 1 0.024
cell cycle phase transition GO:0044770 173 0.024
Fly
regulation of transferase activity GO:0051338 355 0.024
neuromuscular junction development GO:0007528 3 0.024
appendage development GO:0048736 23 0.024
prostate gland morphogenesis GO:0060512 1 0.024
osteoblast differentiation GO:0001649 92 0.024
Human Mouse
tongue development GO:0043586 1 0.024
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.024
Worm
establishment of protein localization to organelle GO:0072594 172 0.024
Mouse
regulation of protein kinase activity GO:0045859 289 0.023
morphogenesis of a polarized epithelium GO:0001738 3 0.023
response to cytokine GO:0034097 232 0.023
rhythmic behavior GO:0007622 2 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
circadian behavior GO:0048512 2 0.023
forebrain generation of neurons GO:0021872 3 0.023
Mouse
cell proliferation in forebrain GO:0021846 1 0.023
Mouse
oxidation reduction process GO:0055114 396 0.023
cerebellum development GO:0021549 2 0.023
response to hormone GO:0009725 175 0.023
positive regulation of cell death GO:0010942 263 0.023
Worm
protein targeting GO:0006605 187 0.023
Mouse
myoblast fusion GO:0007520 1 0.023
appendage morphogenesis GO:0035107 16 0.023
regulation of neurogenesis GO:0050767 82 0.023
Mouse
negative regulation of protein phosphorylation GO:0001933 140 0.023
mesenchyme development GO:0060485 59 0.023
regulation of osteoblast differentiation GO:0045667 38 0.023
Mouse
negative regulation of cell cycle GO:0045786 193 0.022
small molecule biosynthetic process GO:0044283 157 0.022
regulation of hormone levels GO:0010817 125 0.022
regulation of kinase activity GO:0043549 314 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
single organism membrane organization GO:0044802 268 0.022
actin filament based process GO:0030029 224 0.022
regulation of cell projection organization GO:0031344 107 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
Worm
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
positive regulation of cell migration GO:0030335 172 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
axis elongation GO:0003401 4 0.022
cellular protein complex assembly GO:0043623 188 0.022
regulation of protein maturation GO:1903317 150 0.022
connective tissue development GO:0061448 39 0.022
Mouse
covalent chromatin modification GO:0016569 254 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
sensory organ development GO:0007423 52 0.022
Mouse Fly
cellular response to cytokine stimulus GO:0071345 181 0.021
nuclear transport GO:0051169 179 0.021
Mouse
negative regulation of epithelial cell migration GO:0010633 38 0.021
cloacal septation GO:0060197 1 0.021
carbohydrate metabolic process GO:0005975 207 0.021
apoptotic signaling pathway GO:0097190 268 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of odontogenesis GO:0042481 4 0.021
memory GO:0007613 3 0.021
glycoprotein metabolic process GO:0009100 110 0.021
response to external biotic stimulus GO:0043207 261 0.021
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.021
Mouse
negative regulation of kidney development GO:0090185 2 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
regulation of cytokine production GO:0001817 232 0.021
regulation of response to external stimulus GO:0032101 222 0.020
sensory perception GO:0007600 103 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
Mouse
innate immune response GO:0045087 178 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.020
chordate embryonic development GO:0043009 34 0.020
Mouse
associative learning GO:0008306 1 0.020
spinal cord patterning GO:0021511 2 0.020
Mouse
reactive oxygen species metabolic process GO:0072593 75 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.020
regulation of dna metabolic process GO:0051052 153 0.020
Human
modification dependent protein catabolic process GO:0019941 209 0.020
cell matrix adhesion GO:0007160 85 0.020
neural crest cell development GO:0014032 3 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
positive regulation of transport GO:0051050 336 0.020
Mouse
immune system development GO:0002520 195 0.020
Mouse
embryonic viscerocranium morphogenesis GO:0048703 1 0.020
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.020
regulation of protein localization to nucleus GO:1900180 85 0.020
Mouse
vesicle mediated transport GO:0016192 371 0.020
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
prostate gland development GO:0030850 3 0.020
limb development GO:0060173 23 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
circulatory system process GO:0003013 113 0.020
negative regulation of protein processing GO:0010955 142 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
adult locomotory behavior GO:0008344 1 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.019
regulation of protein catabolic process GO:0042176 155 0.019
specification of organ identity GO:0010092 3 0.019
Mouse
negative regulation of axon guidance GO:1902668 1 0.019
chemical homeostasis GO:0048878 306 0.019
lens morphogenesis in camera type eye GO:0002089 2 0.019
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.019
lung alveolus development GO:0048286 4 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
regulation of growth GO:0040008 165 0.019
histone modification GO:0016570 251 0.019
negative regulation of proteolysis GO:0045861 132 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.018
Mouse Fly
neuroblast proliferation GO:0007405 4 0.018
Mouse
male genitalia development GO:0030539 1 0.018
regulation of immune response GO:0050776 201 0.018
syncytium formation by plasma membrane fusion GO:0000768 2 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
ion transmembrane transport GO:0034220 338 0.018
negative regulation of transport GO:0051051 176 0.018
regulation of vasculature development GO:1901342 97 0.018
neuron projection regeneration GO:0031102 1 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
Worm
ventral spinal cord interneuron fate commitment GO:0060579 1 0.018
Mouse
protein oligomerization GO:0051259 173 0.018
response to biotic stimulus GO:0009607 276 0.018
Human
photoreceptor cell differentiation GO:0046530 2 0.018
response to organic cyclic compound GO:0014070 204 0.018
cuticle development GO:0042335 1 0.018
Fly
positive regulation of transferase activity GO:0051347 227 0.018
actin cytoskeleton organization GO:0030036 207 0.018
regulation of binding GO:0051098 111 0.018
negative regulation of cell growth GO:0030308 83 0.018
regulation of organ formation GO:0003156 4 0.018
nephric duct development GO:0072176 4 0.017
regulation of stem cell differentiation GO:2000736 56 0.017
epithelial cell proliferation GO:0050673 128 0.017
negative regulation of protein maturation GO:1903318 142 0.017
response to axon injury GO:0048678 1 0.017
hair follicle morphogenesis GO:0031069 2 0.017
regulation of glial cell proliferation GO:0060251 4 0.017
response to other organism GO:0051707 261 0.017
Human
salivary gland morphogenesis GO:0007435 4 0.017
cellular lipid metabolic process GO:0044255 303 0.017
axon regeneration GO:0031103 1 0.017
stem cell division GO:0017145 2 0.017
endomembrane system organization GO:0010256 196 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
tripartite regional subdivision GO:0007351 2 0.017
forebrain neuron development GO:0021884 2 0.017
regulation of endothelial cell migration GO:0010594 67 0.017
secretion GO:0046903 254 0.017
endothelial cell migration GO:0043542 86 0.017
cell growth GO:0016049 160 0.017
cell chemotaxis GO:0060326 112 0.017
muscle structure development GO:0061061 98 0.017
response to lipid GO:0033993 206 0.017
single organism nuclear import GO:1902593 104 0.017
Mouse
myeloid cell differentiation GO:0030099 117 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
autonomic nervous system development GO:0048483 1 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
axon development GO:0061564 34 0.017
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.017
negative regulation of cell adhesion GO:0007162 64 0.017
lipid localization GO:0010876 106 0.017
behavior GO:0007610 112 0.016
protein targeting to nucleus GO:0044744 104 0.016
Mouse
mesenchymal cell development GO:0014031 50 0.016
neural tube patterning GO:0021532 2 0.016
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.016
Fly
cell activation GO:0001775 213 0.016
Mouse
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
Mouse
regulation of protein processing GO:0070613 150 0.016
hindlimb morphogenesis GO:0035137 2 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
Fly
spermatid differentiation GO:0048515 4 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
response to transforming growth factor beta GO:0071559 94 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
eye morphogenesis GO:0048592 16 0.016
Mouse Fly
protein localization to nucleus GO:0034504 136 0.016
Mouse
positive regulation of immune response GO:0050778 159 0.016
neural tube development GO:0021915 9 0.016
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
mesenchymal cell differentiation GO:0048762 52 0.016
regulation of cell growth GO:0001558 135 0.016
spermatid development GO:0007286 4 0.016
epidermis development GO:0008544 59 0.016
Human Fly

GLI3 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.074
connective tissue disease DOID:65 109 0.048
cancer DOID:162 167 0.038
disease of cellular proliferation DOID:14566 174 0.038
bone development disease DOID:0080006 55 0.037
bone disease DOID:0080001 88 0.037
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030
organ system cancer DOID:0050686 164 0.026
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.021
disease of metabolism DOID:0014667 295 0.020
central nervous system disease DOID:331 186 0.018
inherited metabolic disorder DOID:655 242 0.018
cardiovascular system disease DOID:1287 106 0.016