Homo sapiens

113 known processes

LONP1

lon peptidase 1, mitochondrial

(Aliases: PIM1,LON,PRSS15,hLON,LonHS,MGC1498,LONP)

LONP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.599
one carbon metabolic process GO:0006730 1 0.416
cellular amino acid metabolic process GO:0006520 116 0.173
nucleobase biosynthetic process GO:0046112 4 0.168
chemical homeostasis GO:0048878 306 0.164
translation GO:0006412 132 0.161
female gamete generation GO:0007292 2 0.142
vesicle mediated transport GO:0016192 371 0.132
trna aminoacylation for protein translation GO:0006418 8 0.130
multicellular organismal aging GO:0010259 3 0.128
oogenesis GO:0048477 2 0.105
response to nitrogen compound GO:1901698 184 0.088
purine containing compound biosynthetic process GO:0072522 88 0.085
amino acid activation GO:0043038 12 0.085
determination of adult lifespan GO:0008340 2 0.083
pigment biosynthetic process GO:0046148 10 0.080
cellular macromolecule catabolic process GO:0044265 380 0.079
embryo development GO:0009790 123 0.067
endocytosis GO:0006897 159 0.065
water soluble vitamin metabolic process GO:0006767 6 0.061
cellular amino acid catabolic process GO:0009063 31 0.061
serine family amino acid catabolic process GO:0009071 5 0.058
response to abiotic stimulus GO:0009628 336 0.056
response to oxygen containing compound GO:1901700 369 0.053
system process GO:0003008 349 0.052
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.051
dicarboxylic acid metabolic process GO:0043648 29 0.051
amine metabolic process GO:0009308 44 0.048
secretion by cell GO:0032940 226 0.047
alpha amino acid catabolic process GO:1901606 26 0.046
purine nucleobase biosynthetic process GO:0009113 3 0.046
oxidation reduction process GO:0055114 396 0.045
serine family amino acid metabolic process GO:0009069 12 0.045
tube development GO:0035295 125 0.044
ribonucleoside monophosphate metabolic process GO:0009161 187 0.043
alpha amino acid metabolic process GO:1901605 72 0.043
coenzyme metabolic process GO:0006732 65 0.043
rna processing GO:0006396 255 0.043
organophosphate catabolic process GO:0046434 430 0.041
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.037
regulation of locomotion GO:0040012 329 0.036
cellular ketone metabolic process GO:0042180 80 0.036
protein catabolic process GO:0030163 325 0.035
organelle assembly GO:0070925 176 0.033
organonitrogen compound biosynthetic process GO:1901566 200 0.032
atp metabolic process GO:0046034 176 0.031
regulation of cell cycle GO:0051726 393 0.031
cellular amine metabolic process GO:0044106 41 0.031
cellular response to endogenous stimulus GO:0071495 336 0.031
mitochondrial rna metabolic process GO:0000959 15 0.030
developmental process involved in reproduction GO:0003006 66 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
positive regulation of hydrolase activity GO:0051345 331 0.030
secretion GO:0046903 254 0.029
organic acid catabolic process GO:0016054 71 0.029
nucleotide catabolic process GO:0009166 408 0.029
cell cell signaling GO:0007267 155 0.028
carboxylic acid catabolic process GO:0046395 71 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
nervous system development GO:0007399 293 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
regulation of multi organism process GO:0043900 157 0.026
organophosphate biosynthetic process GO:0090407 163 0.025
biological adhesion GO:0022610 331 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
maintenance of location GO:0051235 112 0.025
mapk cascade GO:0000165 288 0.024
cofactor metabolic process GO:0051186 87 0.024
patterning of blood vessels GO:0001569 2 0.024
regulation of transferase activity GO:0051338 355 0.024
regulation of immune response GO:0050776 201 0.023
embryo development ending in birth or egg hatching GO:0009792 34 0.023
cell adhesion GO:0007155 325 0.023
positive regulation of catabolic process GO:0009896 310 0.022
spermatid development GO:0007286 4 0.022
ncrna metabolic process GO:0034660 108 0.022
cellular response to hormone stimulus GO:0032870 125 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
response to hormone GO:0009725 175 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
cellular protein complex assembly GO:0043623 188 0.021
Yeast
mitochondrion organization GO:0007005 156 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
single organism reproductive process GO:0044702 98 0.021
atp catabolic process GO:0006200 157 0.021
mrna metabolic process GO:0016071 175 0.020
receptor mediated endocytosis GO:0006898 84 0.020
reproduction GO:0000003 63 0.020
cellular modified amino acid metabolic process GO:0006575 64 0.020
protein ubiquitination GO:0016567 314 0.019
reproductive system development GO:0061458 56 0.019
circulatory system development GO:0072359 262 0.019
immune effector process GO:0002252 159 0.019
cellular response to nutrient levels GO:0031669 69 0.019
single organism cellular localization GO:1902580 332 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
embryonic morphogenesis GO:0048598 85 0.019
regulation of kinase activity GO:0043549 314 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
l serine metabolic process GO:0006563 5 0.018
regulation of response to external stimulus GO:0032101 222 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
immune response GO:0006955 307 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
negative regulation of protein modification process GO:0031400 200 0.018
pyruvate metabolic process GO:0006090 26 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
protein maturation GO:0051604 233 0.017
reproductive structure development GO:0048608 55 0.017
regulation of oxidoreductase activity GO:0051341 43 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
cellular response to starvation GO:0009267 58 0.017
regulation of protein kinase activity GO:0045859 289 0.017
segmentation GO:0035282 4 0.017
reproductive process GO:0022414 106 0.016
protein oligomerization GO:0051259 173 0.016
thymus development GO:0048538 3 0.016
cellular component morphogenesis GO:0032989 314 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
vasculature development GO:0001944 181 0.016
cytoplasmic transport GO:0016482 379 0.016
response to organonitrogen compound GO:0010243 156 0.016
nucleoside catabolic process GO:0009164 408 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
blastoderm segmentation GO:0007350 2 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
chordate embryonic development GO:0043009 34 0.015
response to extracellular stimulus GO:0009991 85 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
negative regulation of developmental process GO:0051093 247 0.014
intracellular protein transport GO:0006886 270 0.014
gonad development GO:0008406 34 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
metencephalon development GO:0022037 2 0.013
membrane organization GO:0061024 292 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
protein refolding GO:0042026 14 0.013
regulation of growth GO:0040008 165 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
cardiovascular system development GO:0072358 262 0.013
nucleobase metabolic process GO:0009112 8 0.012
neurological system process GO:0050877 163 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
regulation of protein processing GO:0070613 150 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
regeneration GO:0031099 4 0.012
protein processing GO:0016485 226 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of secretion by cell GO:1903530 177 0.012
epithelium development GO:0060429 227 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
cell morphogenesis GO:0000902 296 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
purine containing compound catabolic process GO:0072523 411 0.011
regulation of map kinase activity GO:0043405 108 0.011
regulation of anatomical structure size GO:0090066 101 0.011
carbohydrate metabolic process GO:0005975 207 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
chromatin organization GO:0006325 351 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
positive regulation of developmental process GO:0051094 314 0.011
aging GO:0007568 66 0.011
cell division GO:0051301 168 0.011
protein acetylation GO:0006473 116 0.011
cell development GO:0048468 328 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
negative regulation of cell proliferation GO:0008285 228 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
rna splicing GO:0008380 131 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
regulation of response to biotic stimulus GO:0002831 55 0.010
nitrogen compound transport GO:0071705 191 0.010

LONP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.132
amino acid metabolic disorder DOID:9252 50 0.132
inherited metabolic disorder DOID:655 242 0.132
central nervous system disease DOID:331 186 0.095
nervous system disease DOID:863 431 0.095
disease of cellular proliferation DOID:14566 174 0.022
neuromuscular disease DOID:440 38 0.018
neuropathy DOID:870 52 0.018
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.016
musculoskeletal system disease DOID:17 223 0.014
hemolytic anemia DOID:583 20 0.012
immune system disease DOID:2914 155 0.012
normocytic anemia DOID:720 20 0.012
anemia DOID:2355 55 0.012
hematopoietic system disease DOID:74 100 0.012