Homo sapiens

0 known processes

SIGLEC8

sialic acid binding Ig-like lectin 8

(Aliases: SIGLEC-8,SAF2,MGC59785,SIGLEC8L)

SIGLEC8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 207 0.203
cellular amino acid metabolic process GO:0006520 116 0.161
cation transport GO:0006812 331 0.109
cellular ketone metabolic process GO:0042180 80 0.108
regulation of cellular amino acid metabolic process GO:0006521 6 0.102
cellular amine metabolic process GO:0044106 41 0.096
positive regulation of phosphorylation GO:0042327 394 0.096
regulation of cellular amine metabolic process GO:0033238 11 0.094
ras protein signal transduction GO:0007265 73 0.087
regulation of cell motility GO:2000145 299 0.071
system process GO:0003008 349 0.069
positive regulation of cellular amine metabolic process GO:0033240 7 0.067
chemical homeostasis GO:0048878 306 0.065
ion homeostasis GO:0050801 230 0.063
post embryonic development GO:0009791 2 0.062
response to oxygen containing compound GO:1901700 369 0.058
nucleoside phosphate catabolic process GO:1901292 412 0.057
regulation of nucleotide metabolic process GO:0006140 269 0.056
transmembrane transport GO:0055085 399 0.056
ion transmembrane transport GO:0034220 338 0.056
regulation of locomotion GO:0040012 329 0.055
regulation of cell differentiation GO:0045595 393 0.055
small gtpase mediated signal transduction GO:0007264 78 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
positive regulation of transport GO:0051050 336 0.053
positive regulation of protein phosphorylation GO:0001934 313 0.049
organophosphate catabolic process GO:0046434 430 0.049
ribonucleoside triphosphate metabolic process GO:0009199 412 0.049
regulation of cellular component movement GO:0051270 334 0.048
locomotory behavior GO:0007626 1 0.048
positive regulation of cell proliferation GO:0008284 301 0.047
positive regulation of catabolic process GO:0009896 310 0.045
purine nucleoside triphosphate metabolic process GO:0009144 412 0.045
regulation of cell migration GO:0030334 289 0.045
secretion GO:0046903 254 0.044
immune response GO:0006955 307 0.044
cation transmembrane transport GO:0098655 238 0.044
response to nitrogen compound GO:1901698 184 0.044
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
negative regulation of cellular amine metabolic process GO:0033239 3 0.043
purine ribonucleoside metabolic process GO:0046128 437 0.042
adult locomotory behavior GO:0008344 1 0.042
organic anion transport GO:0015711 103 0.042
lipid metabolic process GO:0006629 381 0.042
calcium ion transport GO:0006816 147 0.041
response to external biotic stimulus GO:0043207 261 0.040
nucleoside triphosphate catabolic process GO:0009143 394 0.040
inorganic ion transmembrane transport GO:0098660 231 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
monocarboxylic acid metabolic process GO:0032787 185 0.040
positive regulation of mapk cascade GO:0043410 190 0.040
ribonucleoside catabolic process GO:0042454 406 0.040
purine containing compound catabolic process GO:0072523 411 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
negative regulation of programmed cell death GO:0043069 321 0.038
positive regulation of protein kinase activity GO:0045860 190 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
positive regulation of immune system process GO:0002684 283 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.037
cellular lipid metabolic process GO:0044255 303 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
response to cytokine GO:0034097 232 0.037
nucleotide catabolic process GO:0009166 408 0.037
amine metabolic process GO:0009308 44 0.037
negative regulation of cellular component organization GO:0051129 235 0.037
Mouse
metal ion transport GO:0030001 272 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
regulation of kinase activity GO:0043549 314 0.036
anion transport GO:0006820 161 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
cellular response to cytokine stimulus GO:0071345 181 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
defense response GO:0006952 315 0.036
Mouse
cytokine production GO:0001816 247 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
response to organic cyclic compound GO:0014070 204 0.035
regulation of response to external stimulus GO:0032101 222 0.035
Mouse
response to biotic stimulus GO:0009607 276 0.035
ribonucleoside triphosphate catabolic process GO:0009203 391 0.035
response to hormone GO:0009725 175 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
cell activation GO:0001775 213 0.034
rho protein signal transduction GO:0007266 26 0.034
vesicle mediated transport GO:0016192 371 0.034
Mouse
oxidation reduction process GO:0055114 396 0.033
actin filament based process GO:0030029 224 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
mapk cascade GO:0000165 288 0.033
regulation of secretion GO:0051046 194 0.033
purine nucleotide catabolic process GO:0006195 405 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
divalent metal ion transport GO:0070838 152 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
cellular chemical homeostasis GO:0055082 180 0.031
purine nucleoside triphosphate catabolic process GO:0009146 392 0.031
response to other organism GO:0051707 261 0.031
regulation of mapk cascade GO:0043408 262 0.031
circulatory system process GO:0003013 113 0.031
secretion by cell GO:0032940 226 0.031
gtp metabolic process GO:0046039 239 0.031
innate immune response GO:0045087 178 0.031
cellular homeostasis GO:0019725 196 0.030
metal ion homeostasis GO:0055065 169 0.030
peptidyl tyrosine modification GO:0018212 170 0.030
regulation of leukocyte activation GO:0002694 115 0.029
immune response activating signal transduction GO:0002757 90 0.029
nucleoside catabolic process GO:0009164 408 0.029
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
determination of adult lifespan GO:0008340 2 0.028
response to lipid GO:0033993 206 0.028
regulation of ion transport GO:0043269 189 0.028
response to wounding GO:0009611 168 0.028
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
response to abiotic stimulus GO:0009628 336 0.028
cation homeostasis GO:0055080 189 0.028
leukocyte migration GO:0050900 107 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
gtp catabolic process GO:0006184 237 0.027
cell projection organization GO:0030030 252 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.027
regulation of protein kinase activity GO:0045859 289 0.026
divalent inorganic cation transport GO:0072511 158 0.026
single organism cellular localization GO:1902580 332 0.026
nicotinate transport GO:2001142 1 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
cell morphogenesis GO:0000902 296 0.026
positive regulation of cell differentiation GO:0045597 211 0.026
positive regulation of kinase activity GO:0033674 204 0.026
multicellular organismal aging GO:0010259 3 0.026
regulation of gtpase activity GO:0043087 180 0.026
hindbrain development GO:0030902 3 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.025
camp metabolic process GO:0046058 61 0.025
positive regulation of cytokine production GO:0001819 167 0.025
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
cellular component morphogenesis GO:0032989 314 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
blood circulation GO:0008015 113 0.024
regulation of gtp catabolic process GO:0033124 180 0.024
protein maturation GO:0051604 233 0.024
organic hydroxy compound metabolic process GO:1901615 147 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
neuromuscular junction development GO:0007528 3 0.024
guanosine containing compound metabolic process GO:1901068 244 0.024
peptidyl tyrosine phosphorylation GO:0018108 170 0.023
regulation of metal ion transport GO:0010959 120 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
response to metal ion GO:0010038 84 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
memory GO:0007613 3 0.023
regulation of cell activation GO:0050865 125 0.023
positive regulation of developmental process GO:0051094 314 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
positive regulation of gtp catabolic process GO:0033126 166 0.023
protein processing GO:0016485 226 0.023
activation of immune response GO:0002253 114 0.023
positive regulation of cellular component movement GO:0051272 181 0.023
organophosphate biosynthetic process GO:0090407 163 0.023
cell development GO:0048468 328 0.022
response to organonitrogen compound GO:0010243 156 0.022
female gamete generation GO:0007292 2 0.022
regulation of cytokine production GO:0001817 232 0.022
fatty acid metabolic process GO:0006631 115 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
camp biosynthetic process GO:0006171 47 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
maintenance of location GO:0051235 112 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
regulation of defense response GO:0031347 154 0.022
Mouse
calcium ion homeostasis GO:0055074 122 0.022
inflammatory response GO:0006954 79 0.021
Mouse
regulation of protein transport GO:0051223 213 0.021
response to bacterium GO:0009617 144 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
regulation of leukocyte migration GO:0002685 63 0.021
oogenesis GO:0048477 2 0.021
positive regulation of transferase activity GO:0051347 227 0.021
cytokine mediated signaling pathway GO:0019221 109 0.021
regulation of immune response GO:0050776 201 0.021
sequestering of calcium ion GO:0051208 17 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
positive regulation of ion transport GO:0043270 87 0.021
cellular divalent inorganic cation homeostasis GO:0072503 128 0.021
negative regulation of cell death GO:0060548 345 0.020
membrane organization GO:0061024 292 0.020
Mouse
neurological system process GO:0050877 163 0.020
positive regulation of cell migration GO:0030335 172 0.020
nervous system development GO:0007399 293 0.020
Human
organic acid transport GO:0015849 65 0.020
generation of neurons GO:0048699 152 0.020
cytoplasmic transport GO:0016482 379 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
negative regulation of transport GO:0051051 176 0.020
Mouse
regulation of intracellular transport GO:0032386 195 0.020
behavior GO:0007610 112 0.020
regeneration GO:0031099 4 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
actin filament based movement GO:0030048 17 0.020
response to virus GO:0009615 126 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
negative regulation of developmental process GO:0051093 247 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
immune response regulating signaling pathway GO:0002764 97 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
carbohydrate metabolic process GO:0005975 207 0.019
single organism cell adhesion GO:0098602 179 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
phospholipid metabolic process GO:0006644 99 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
muscle contraction GO:0006936 73 0.019
cellular response to dna damage stimulus GO:0006974 379 0.018
mating GO:0007618 1 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
regulation of proteolysis GO:0030162 293 0.018
regulation of transferase activity GO:0051338 355 0.018
dephosphorylation GO:0016311 209 0.018
cellular protein complex assembly GO:0043623 188 0.018
protein localization to membrane GO:0072657 160 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.018
central nervous system development GO:0007417 123 0.018
Human
forebrain generation of neurons GO:0021872 3 0.018
protein oligomerization GO:0051259 173 0.018
single organism membrane organization GO:0044802 268 0.018
purine nucleotide biosynthetic process GO:0006164 84 0.018
ribose phosphate biosynthetic process GO:0046390 82 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
biological adhesion GO:0022610 331 0.018
Mouse
protein catabolic process GO:0030163 325 0.018
cyclic nucleotide metabolic process GO:0009187 82 0.018
protein localization to organelle GO:0033365 280 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
urate transport GO:0015747 3 0.018
associative learning GO:0008306 1 0.018
lipid biosynthetic process GO:0008610 177 0.018
wound healing GO:0042060 115 0.018
neuron differentiation GO:0030182 138 0.018
regulation of protein processing GO:0070613 150 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
regulation of camp metabolic process GO:0030814 52 0.017
negative regulation of locomotion GO:0040013 118 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
regulation of protein localization GO:0032880 296 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
sequestering of metal ion GO:0051238 24 0.017
negative regulation of cell motility GO:2000146 104 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
neurogenesis GO:0022008 169 0.017
intracellular protein transport GO:0006886 270 0.017
immune system development GO:0002520 195 0.017
second messenger mediated signaling GO:0019932 78 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
endomembrane system organization GO:0010256 196 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
motor neuron axon guidance GO:0008045 2 0.017
muscle system process GO:0003012 81 0.017
regulation of synaptic plasticity GO:0048167 3 0.017
tissue homeostasis GO:0001894 63 0.017
chromatin organization GO:0006325 351 0.017
regulation of homeostatic process GO:0032844 121 0.017
cell adhesion GO:0007155 325 0.017
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
anatomical structure homeostasis GO:0060249 100 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
ribonucleotide biosynthetic process GO:0009260 81 0.016
actin mediated cell contraction GO:0070252 12 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
Mouse
regulation of camp biosynthetic process GO:0030817 45 0.016
taxis GO:0042330 157 0.016
cyclic purine nucleotide metabolic process GO:0052652 60 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
positive regulation of secretion GO:0051047 116 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
positive regulation of organic acid transport GO:0032892 3 0.016
cellular ion homeostasis GO:0006873 168 0.016
regulation of cell cycle GO:0051726 393 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
anion transmembrane transport GO:0098656 76 0.016
nitrogen compound transport GO:0071705 191 0.016
positive regulation of immune response GO:0050778 159 0.016
regulation of eosinophil activation GO:1902566 2 0.016
regulation of calcium ion transport GO:0051924 79 0.016
regulation of protein maturation GO:1903317 150 0.016
regulation of lymphocyte activation GO:0051249 103 0.016
epidermis morphogenesis GO:0048730 3 0.016
cellular protein catabolic process GO:0044257 261 0.016
cell cell signaling GO:0007267 155 0.016
response to peptide GO:1901652 65 0.016
response to inorganic substance GO:0010035 127 0.016
purine containing compound biosynthetic process GO:0072522 88 0.016
hemopoiesis GO:0030097 180 0.015
metencephalon development GO:0022037 2 0.015
regulation of actin filament based process GO:0032970 141 0.015
cytosolic calcium ion homeostasis GO:0051480 89 0.015
regulation of anatomical structure size GO:0090066 101 0.015
small molecule biosynthetic process GO:0044283 157 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
positive regulation of cell death GO:0010942 263 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
negative regulation of immune system process GO:0002683 136 0.015
protein secretion GO:0009306 98 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of ion homeostasis GO:2000021 73 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
striated muscle contraction GO:0006941 52 0.015
regulation of erk1 and erk2 cascade GO:0070372 99 0.015
forebrain neuron differentiation GO:0021879 3 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
apoptotic signaling pathway GO:0097190 268 0.015
cell growth GO:0016049 160 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
regulation of cellular response to stress GO:0080135 244 0.015
sensory perception GO:0007600 103 0.015
negative regulation of icosanoid secretion GO:0032304 2 0.015
actin cytoskeleton organization GO:0030036 207 0.014
regulation of membrane potential GO:0042391 95 0.014
negative regulation of secretion GO:0051048 58 0.014
lymphocyte proliferation GO:0046651 70 0.014
negative regulation of cytokine production GO:0001818 82 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
endocytosis GO:0006897 159 0.014
Mouse
reactive oxygen species biosynthetic process GO:1903409 4 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.014
single organismal cell cell adhesion GO:0016337 148 0.014
immune effector process GO:0002252 159 0.014
visual learning GO:0008542 1 0.014
sensory perception of taste GO:0050909 36 0.014
organic acid biosynthetic process GO:0016053 97 0.014
rhythmic behavior GO:0007622 2 0.014
spermatid differentiation GO:0048515 4 0.014
regulation of t cell activation GO:0050863 77 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
negative regulation of protein processing GO:0010955 142 0.014
response to alcohol GO:0097305 64 0.014
regulation of cell cycle process GO:0010564 266 0.014
segmentation GO:0035282 4 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of response to wounding GO:1903034 101 0.014
Mouse
organic hydroxy compound transport GO:0015850 63 0.014
growth GO:0040007 202 0.014
epithelium development GO:0060429 227 0.014
erk1 and erk2 cascade GO:0070371 104 0.014
monovalent inorganic cation transport GO:0015672 128 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
cell projection morphogenesis GO:0048858 129 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.013
regulation of protein complex assembly GO:0043254 147 0.013
head development GO:0060322 108 0.013
Human
copulation GO:0007620 1 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
carboxylic acid transport GO:0046942 63 0.013
regulation of protein catabolic process GO:0042176 155 0.013
compound eye development GO:0048749 1 0.013
organ morphogenesis GO:0009887 147 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
protein ubiquitination GO:0016567 314 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
positive regulation of cell motility GO:2000147 177 0.013
regulation of cell development GO:0060284 161 0.013
response to hypoxia GO:0001666 96 0.013
chemotaxis GO:0006935 157 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
negative regulation of transferase activity GO:0051348 124 0.013
regulation of nucleotide biosynthetic process GO:0030808 50 0.013
cellular response to organic cyclic compound GO:0071407 127 0.013
myeloid leukocyte differentiation GO:0002573 60 0.013
action potential GO:0001508 34 0.013
negative regulation of phagocytosis GO:0050765 4 0.013
Mouse
leukocyte activation GO:0045321 164 0.013
av node cell to bundle of his cell communication GO:0086067 4 0.013
regulation of lipase activity GO:0060191 37 0.012
response to fungus GO:0009620 4 0.012
neuron development GO:0048666 113 0.012
peripheral nervous system development GO:0007422 2 0.012
circadian behavior GO:0048512 2 0.012
negative regulation of protein modification process GO:0031400 200 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.012
digestive system process GO:0022600 17 0.012
activation of protein kinase activity GO:0032147 90 0.012
regulation of map kinase activity GO:0043405 108 0.012
defense response to other organism GO:0098542 129 0.012
jak stat cascade GO:0007259 46 0.012
lipid transport GO:0006869 90 0.012
ossification GO:0001503 121 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.012
glycerolipid metabolic process GO:0046486 107 0.012
cell substrate adhesion GO:0031589 132 0.012
cell part morphogenesis GO:0032990 137 0.012
angiogenesis GO:0001525 147 0.012
limbic system development GO:0021761 3 0.012
cerebellum development GO:0021549 2 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
positive regulation of calcium ion transport GO:0051928 51 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.012
blastoderm segmentation GO:0007350 2 0.012
sensory perception of pain GO:0019233 4 0.012
response to oxygen levels GO:0070482 100 0.012
positive regulation of locomotion GO:0040017 186 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
lipid localization GO:0010876 106 0.012
regulation of immune effector process GO:0002697 91 0.012
visual behavior GO:0007632 2 0.012
myeloid cell differentiation GO:0030099 117 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
response to steroid hormone GO:0048545 80 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
plasma membrane organization GO:0007009 115 0.012
negative regulation of proteolysis GO:0045861 132 0.012
regulation of dephosphorylation GO:0035303 96 0.012
mitotic cell cycle GO:0000278 326 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
brain development GO:0007420 97 0.012
Human
leukocyte differentiation GO:0002521 98 0.012
cardiovascular system development GO:0072358 262 0.012
negative regulation of peptidase activity GO:0010466 91 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
rna processing GO:0006396 255 0.011
positive regulation of vasoconstriction GO:0045907 3 0.011
regulation of transmembrane transport GO:0034762 139 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
lipid catabolic process GO:0016042 84 0.011
microtubule based process GO:0007017 210 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
leukocyte mediated immunity GO:0002443 59 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
response to peptide hormone GO:0043434 61 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
chromatin modification GO:0016568 298 0.011
spermatid development GO:0007286 4 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
digestion GO:0007586 22 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of binding GO:0051098 111 0.011
organelle assembly GO:0070925 176 0.011
anterior posterior axis specification GO:0009948 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
protein targeting GO:0006605 187 0.011
behavioral response to ethanol GO:0048149 2 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
positive regulation of camp biosynthetic process GO:0030819 35 0.011
negative regulation of eosinophil migration GO:2000417 2 0.011
cyclic nucleotide biosynthetic process GO:0009190 61 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
regulation of transporter activity GO:0032409 82 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
cytokine secretion GO:0050663 64 0.011
regulation of vasculature development GO:1901342 97 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011

SIGLEC8 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.037
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
disease of metabolism DOID:0014667 295 0.020
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
hematopoietic system disease DOID:74 100 0.018
inherited metabolic disorder DOID:655 242 0.017
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
retinal disease DOID:5679 118 0.011
cardiovascular system disease DOID:1287 106 0.011
central nervous system disease DOID:331 186 0.011