Homo sapiens

0 known processes

SIGLEC5

sialic acid binding Ig-like lectin 5

(Aliases: OBBP2,CD170,SIGLEC-5,OB-BP2,CD33L2)

SIGLEC5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
immune response GO:0006955 307 0.309
response to other organism GO:0051707 261 0.288
positive regulation of cytokine production GO:0001819 167 0.207
response to external biotic stimulus GO:0043207 261 0.201
defense response GO:0006952 315 0.196
response to biotic stimulus GO:0009607 276 0.185
regulation of cytokine production GO:0001817 232 0.182
cell activation GO:0001775 213 0.180
cytokine production GO:0001816 247 0.152
positive regulation of immune system process GO:0002684 283 0.148
vesicle mediated transport GO:0016192 371 0.138
hemopoiesis GO:0030097 180 0.134
regulation of cell activation GO:0050865 125 0.133
regulation of protein secretion GO:0050708 86 0.122
regulation of secretion by cell GO:1903530 177 0.120
positive regulation of immune response GO:0050778 159 0.113
biological adhesion GO:0022610 331 0.110
regulation of secretion GO:0051046 194 0.100
leukocyte activation GO:0045321 164 0.097
t cell activation GO:0042110 99 0.092
response to bacterium GO:0009617 144 0.091
regulation of immune response GO:0050776 201 0.091
secretion GO:0046903 254 0.090
positive regulation of hydrolase activity GO:0051345 331 0.090
negative regulation of cell death GO:0060548 345 0.088
lymphocyte activation GO:0046649 133 0.087
regulation of protein localization GO:0032880 296 0.087
leukocyte migration GO:0050900 107 0.086
regulation of lymphocyte activation GO:0051249 103 0.086
response to oxygen containing compound GO:1901700 369 0.084
regulation of leukocyte activation GO:0002694 115 0.084
positive regulation of transport GO:0051050 336 0.080
secretion by cell GO:0032940 226 0.079
regulation of mononuclear cell proliferation GO:0032944 65 0.079
cell adhesion GO:0007155 325 0.077
immune effector process GO:0002252 159 0.073
regulation of protein transport GO:0051223 213 0.073
immune response regulating signaling pathway GO:0002764 97 0.072
regulation of response to external stimulus GO:0032101 222 0.072
regulation of t cell activation GO:0050863 77 0.069
defense response to virus GO:0051607 71 0.069
regulation of defense response GO:0031347 154 0.067
mapk cascade GO:0000165 288 0.066
innate immune response GO:0045087 178 0.065
signal transduction by phosphorylation GO:0023014 297 0.064
regulation of gamma delta t cell activation involved in immune response GO:2001191 1 0.064
regulation of cytokine secretion GO:0050707 57 0.064
negative regulation of transport GO:0051051 176 0.064
positive regulation of cell proliferation GO:0008284 301 0.062
cell development GO:0048468 328 0.061
immune response activating signal transduction GO:0002757 90 0.059
cation transport GO:0006812 331 0.059
single organismal cell cell adhesion GO:0016337 148 0.058
single organism cell adhesion GO:0098602 179 0.057
negative regulation of alpha beta t cell activation GO:0046636 3 0.057
negative regulation of multicellular organismal process GO:0051241 317 0.056
regulation of establishment of protein localization GO:0070201 242 0.056
negative regulation of programmed cell death GO:0043069 321 0.056
defense response to other organism GO:0098542 129 0.055
cytokine secretion GO:0050663 64 0.055
positive regulation of mapk cascade GO:0043410 190 0.054
amine metabolic process GO:0009308 44 0.051
activation of immune response GO:0002253 114 0.050
positive regulation of phosphorylation GO:0042327 394 0.050
negative regulation of interleukin 12 secretion GO:2001183 1 0.050
post embryonic development GO:0009791 2 0.049
regulation of eosinophil activation GO:1902566 2 0.049
negative regulation of phagocytosis engulfment GO:0060101 1 0.049
mononuclear cell proliferation GO:0032943 71 0.049
protein secretion GO:0009306 98 0.049
regulation of nk t cell activation GO:0051133 4 0.048
regulation of cellular component movement GO:0051270 334 0.047
regulation of mapk cascade GO:0043408 262 0.047
regulation of cell differentiation GO:0045595 393 0.046
response to cytokine GO:0034097 232 0.045
cytoplasmic transport GO:0016482 379 0.045
immune system development GO:0002520 195 0.045
nitrogen compound transport GO:0071705 191 0.045
negative regulation of cell proliferation GO:0008285 228 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
cellular amine metabolic process GO:0044106 41 0.044
anatomical structure formation involved in morphogenesis GO:0048646 284 0.043
hematopoietic or lymphoid organ development GO:0048534 186 0.043
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.043
negative regulation of secretion GO:0051048 58 0.042
negative regulation of secretion by cell GO:1903531 52 0.042
regulation of vesicle mediated transport GO:0060627 130 0.041
positive regulation of developmental process GO:0051094 314 0.041
negative regulation of phagocytosis GO:0050765 4 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
angiogenesis GO:0001525 147 0.039
negative regulation of protein metabolic process GO:0051248 391 0.039
small gtpase mediated signal transduction GO:0007264 78 0.039
positive regulation of lymphocyte activation GO:0051251 73 0.038
chemical homeostasis GO:0048878 306 0.038
myeloid cell differentiation GO:0030099 117 0.038
regulation of metal ion transport GO:0010959 120 0.038
cd8 positive alpha beta t cell activation GO:0036037 3 0.037
cellular amino acid metabolic process GO:0006520 116 0.037
regulation of proteolysis GO:0030162 293 0.037
negative regulation of cellular component organization GO:0051129 235 0.037
positive regulation of cell death GO:0010942 263 0.037
system process GO:0003008 349 0.037
positive regulation of secretion by cell GO:1903532 108 0.036
regulation of cytokine biosynthetic process GO:0042035 35 0.036
regulation of leukocyte migration GO:0002685 63 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
response to lipid GO:0033993 206 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.035
positive regulation of cell differentiation GO:0045597 211 0.035
apoptotic signaling pathway GO:0097190 268 0.035
regulation of cell motility GO:2000145 299 0.035
divalent metal ion transport GO:0070838 152 0.035
cation homeostasis GO:0055080 189 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
regulation of immune effector process GO:0002697 91 0.034
positive regulation of protein secretion GO:0050714 60 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
regulation of lymphocyte proliferation GO:0050670 64 0.034
response to virus GO:0009615 126 0.034
endocytosis GO:0006897 159 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
myeloid leukocyte migration GO:0097529 62 0.033
interleukin 12 secretion GO:0072610 1 0.033
positive regulation of apoptotic process GO:0043065 246 0.033
response to molecule of bacterial origin GO:0002237 82 0.033
g protein coupled receptor signaling pathway GO:0007186 207 0.033
regulation of cell cycle GO:0051726 393 0.032
vasculature development GO:0001944 181 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
metal ion transport GO:0030001 272 0.032
positive regulation of secretion GO:0051047 116 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
positive regulation of protein transport GO:0051222 135 0.032
female gamete generation GO:0007292 2 0.032
response to lipopolysaccharide GO:0032496 70 0.032
small molecule biosynthetic process GO:0044283 157 0.032
regulation of t cell proliferation GO:0042129 42 0.031
regulation of calcium ion transport GO:0051924 79 0.031
detection of chemical stimulus GO:0009593 55 0.031
defense response to bacterium GO:0042742 63 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
regulation of transferase activity GO:0051338 355 0.031
cellular response to oxygen containing compound GO:1901701 276 0.031
purine containing compound catabolic process GO:0072523 411 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
cation transmembrane transport GO:0098655 238 0.030
inflammatory response GO:0006954 79 0.030
cellular ketone metabolic process GO:0042180 80 0.030
cell chemotaxis GO:0060326 112 0.030
regulation of locomotion GO:0040012 329 0.030
regulation of cell migration GO:0030334 289 0.030
purine ribonucleoside catabolic process GO:0046130 398 0.029
regulation of kinase activity GO:0043549 314 0.029
regulation of ion transport GO:0043269 189 0.029
glycosyl compound catabolic process GO:1901658 413 0.029
divalent inorganic cation transport GO:0072511 158 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
taxis GO:0042330 157 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
response to wounding GO:0009611 168 0.028
positive regulation of leukocyte activation GO:0002696 80 0.028
anatomical structure homeostasis GO:0060249 100 0.028
cellular cation homeostasis GO:0030003 163 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
determination of adult lifespan GO:0008340 2 0.028
regulation of innate immune response GO:0045088 97 0.028
lymphocyte proliferation GO:0046651 70 0.028
ion homeostasis GO:0050801 230 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
blood vessel morphogenesis GO:0048514 162 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
negative regulation of developmental process GO:0051093 247 0.027
blood vessel development GO:0001568 172 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
regulation of intracellular transport GO:0032386 195 0.027
cytokine mediated signaling pathway GO:0019221 109 0.027
cellular response to cytokine stimulus GO:0071345 181 0.027
regulation of protein kinase activity GO:0045859 289 0.027
multicellular organismal aging GO:0010259 3 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
regulation of cellular response to stress GO:0080135 244 0.027
innate immune response activating signal transduction GO:0002758 48 0.027
cellular ion homeostasis GO:0006873 168 0.027
negative regulation of cd8 positive alpha beta t cell activation GO:2001186 1 0.027
organophosphate catabolic process GO:0046434 430 0.027
oogenesis GO:0048477 2 0.027
cytokine production involved in immune response GO:0002367 27 0.026
nucleoside catabolic process GO:0009164 408 0.026
positive regulation of proteolysis GO:0045862 142 0.026
negative regulation of cellular amine metabolic process GO:0033239 3 0.026
regulation of cell development GO:0060284 161 0.026
cellular lipid metabolic process GO:0044255 303 0.026
midbrain development GO:0030901 45 0.026
Human
regulation of phagocytosis engulfment GO:0060099 2 0.026
protein oligomerization GO:0051259 173 0.026
lipid metabolic process GO:0006629 381 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
cardiovascular system development GO:0072358 262 0.026
chemotaxis GO:0006935 157 0.026
cellular metal ion homeostasis GO:0006875 146 0.026
cytokine biosynthetic process GO:0042089 37 0.026
positive regulation of programmed cell death GO:0043068 249 0.025
cellular homeostasis GO:0019725 196 0.025
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.025
erk1 and erk2 cascade GO:0070371 104 0.025
positive regulation of transferase activity GO:0051347 227 0.025
cellular chemical homeostasis GO:0055082 180 0.025
membrane organization GO:0061024 292 0.025
nervous system development GO:0007399 293 0.025
Human
transmembrane transport GO:0055085 399 0.025
protein localization to organelle GO:0033365 280 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
single organism cellular localization GO:1902580 332 0.025
negative regulation of cytokine production GO:0001818 82 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
regulation of homeostatic process GO:0032844 121 0.025
positive regulation of cell activation GO:0050867 81 0.025
positive regulation of cytokine secretion GO:0050715 42 0.025
pattern recognition receptor signaling pathway GO:0002221 48 0.025
cellular component morphogenesis GO:0032989 314 0.025
leukocyte mediated immunity GO:0002443 59 0.025
regulation of leukocyte proliferation GO:0070663 67 0.025
calcium ion transport GO:0006816 147 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
circulatory system development GO:0072359 262 0.024
nucleotide catabolic process GO:0009166 408 0.024
regulation of peptidase activity GO:0052547 180 0.024
maintenance of location GO:0051235 112 0.024
cellular response to molecule of bacterial origin GO:0071219 62 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
negative regulation of nk t cell activation GO:0051134 1 0.024
mature dendritic cell differentiation GO:0097029 2 0.024
oxidation reduction process GO:0055114 396 0.024
regulation of dendritic cell apoptotic process GO:2000668 4 0.024
positive regulation of kinase activity GO:0033674 204 0.024
leukocyte chemotaxis GO:0030595 76 0.024
ras protein signal transduction GO:0007265 73 0.024
response to nitrogen compound GO:1901698 184 0.024
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.024
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.024
positive regulation of interleukin 8 production GO:0032757 36 0.024
head development GO:0060322 108 0.023
Human
leukocyte differentiation GO:0002521 98 0.023
regulation of cell adhesion GO:0030155 166 0.023
response to abiotic stimulus GO:0009628 336 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
cell projection organization GO:0030030 252 0.023
enzyme linked receptor protein signaling pathway GO:0007167 303 0.023
dephosphorylation GO:0016311 209 0.023
positive regulation of organelle organization GO:0010638 195 0.023
regulation of erk1 and erk2 cascade GO:0070372 99 0.023
actin filament based process GO:0030029 224 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.023
memory GO:0007613 3 0.023
negative regulation of protein modification process GO:0031400 200 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
granulocyte migration GO:0097530 40 0.022
regulation of interleukin 8 production GO:0032677 49 0.022
regulation of multi organism process GO:0043900 157 0.022
serotonin transport GO:0006837 3 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
positive regulation of innate immune response GO:0045089 79 0.022
positive regulation of catabolic process GO:0009896 310 0.022
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.022
neuromuscular junction development GO:0007528 3 0.022
positive regulation of locomotion GO:0040017 186 0.022
regulation of lymphocyte mediated immunity GO:0002706 33 0.022
covalent chromatin modification GO:0016569 254 0.021
lipid biosynthetic process GO:0008610 177 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
metal ion homeostasis GO:0055065 169 0.021
multicellular organismal homeostasis GO:0048871 67 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
protein homooligomerization GO:0051260 100 0.021
protein processing GO:0016485 226 0.021
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.020
chromatin organization GO:0006325 351 0.020
calcium ion homeostasis GO:0055074 122 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
leukocyte proliferation GO:0070661 74 0.020
mitotic cell cycle GO:0000278 326 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
gtp catabolic process GO:0006184 237 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
response to fungus GO:0009620 4 0.020
central nervous system development GO:0007417 123 0.020
Human
negative regulation of phosphorylation GO:0042326 174 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
regulation of osteoclast development GO:2001204 1 0.020
chromatin modification GO:0016568 298 0.020
interleukin 8 production GO:0032637 51 0.020
regulation of tumor necrosis factor production GO:0032680 43 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.020
cellular response to lipopolysaccharide GO:0071222 57 0.019
cell morphogenesis GO:0000902 296 0.019
positive regulation of cell adhesion GO:0045785 84 0.019
positive regulation of peptidase activity GO:0010952 88 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
sensory perception GO:0007600 103 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.019
regulation of gamma delta t cell activation GO:0046643 1 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.019
positive regulation of cell motility GO:2000147 177 0.019
negative regulation of eosinophil migration GO:2000417 2 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
negative regulation of interferon beta production GO:0032688 4 0.018
positive regulation of t cell activation GO:0050870 54 0.018
protein maturation GO:0051604 233 0.018
amide transport GO:0042886 76 0.018
immune response in mucosal associated lymphoid tissue GO:0002386 1 0.018
negative regulation of immune system process GO:0002683 136 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
positive regulation of leukocyte proliferation GO:0070665 48 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
cellular response to lipid GO:0071396 127 0.018
regulation of ion homeostasis GO:2000021 73 0.018
cell killing GO:0001906 34 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
myeloid leukocyte differentiation GO:0002573 60 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
associative learning GO:0008306 1 0.017
myeloid leukocyte activation GO:0002274 34 0.017
regulation of response to wounding GO:1903034 101 0.017
rho protein signal transduction GO:0007266 26 0.017
activation of innate immune response GO:0002218 55 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
positive regulation of defense response GO:0031349 87 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.017
regulation of map kinase activity GO:0043405 108 0.017
blood circulation GO:0008015 113 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
positive regulation of leukocyte differentiation GO:1902107 37 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
detection of stimulus GO:0051606 85 0.017
positive regulation of mononuclear cell proliferation GO:0032946 47 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
regulation of endocytosis GO:0030100 72 0.017
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.017
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.017
negative regulation of protein transport GO:0051224 75 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
organic hydroxy compound transport GO:0015850 63 0.017
nk t cell activation GO:0051132 4 0.016
sequestering of metal ion GO:0051238 24 0.016
peptide transport GO:0015833 74 0.016
cell division GO:0051301 168 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of cell cycle process GO:0010564 266 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
mitotic cell cycle process GO:1903047 286 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
neural nucleus development GO:0048857 47 0.016
Human
positive regulation of cellular component movement GO:0051272 181 0.016
negative regulation of transferase activity GO:0051348 124 0.016
second messenger mediated signaling GO:0019932 78 0.016
microtubule based process GO:0007017 210 0.016
mucosal immune response GO:0002385 21 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.016
neurological system process GO:0050877 163 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
tissue homeostasis GO:0001894 63 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
positive regulation of cell migration GO:0030335 172 0.015
actin cytoskeleton organization GO:0030036 207 0.015
regulation of regulatory t cell differentiation GO:0045589 4 0.015
negative regulation of cell cycle GO:0045786 193 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
positive regulation of t cell tolerance induction GO:0002666 2 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
negative regulation of tumor necrosis factor biosynthetic process GO:0042536 3 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
osteoclast development GO:0036035 2 0.015
spermatid differentiation GO:0048515 4 0.015
oocyte development GO:0048599 1 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
muscle system process GO:0003012 81 0.015
cytokine metabolic process GO:0042107 38 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
protein catabolic process GO:0030163 325 0.015
histone modification GO:0016570 251 0.015
positive regulation of regulatory t cell differentiation GO:0045591 3 0.015
regulation of angiogenesis GO:0045765 92 0.015
negative regulation of protein secretion GO:0050709 29 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
calcium mediated signaling GO:0019722 44 0.015
brain development GO:0007420 97 0.015
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
phagocytosis recognition GO:0006910 3 0.015
blood coagulation GO:0007596 76 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.014
substantia nigra development GO:0021762 45 0.014
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
tumor necrosis factor production GO:0032640 43 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
sequestering of calcium ion GO:0051208 17 0.014
negative regulation of dendritic cell differentiation GO:2001199 2 0.014
regulation of peptide transport GO:0090087 62 0.014
ion transmembrane transport GO:0034220 338 0.014
single organism membrane organization GO:0044802 268 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
regulation of leukocyte mediated immunity GO:0002703 38 0.014
regulation of gtpase activity GO:0043087 180 0.014
positive regulation of immune effector process GO:0002699 40 0.014
regulation of dephosphorylation GO:0035303 96 0.014
segmentation GO:0035282 4 0.014
gtp metabolic process GO:0046039 239 0.014
stress activated mapk cascade GO:0051403 93 0.014
oocyte differentiation GO:0009994 2 0.014
positive regulation of cytolysis GO:0045919 3 0.014
positive regulation of leukocyte migration GO:0002687 46 0.014
cytosolic calcium ion homeostasis GO:0051480 89 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
actin filament based movement GO:0030048 17 0.014
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
interferon beta secretion GO:0035546 1 0.013
fatty acid metabolic process GO:0006631 115 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
epithelium migration GO:0090132 119 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
regulation of interleukin 12 secretion GO:2001182 1 0.013
organic acid biosynthetic process GO:0016053 97 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.013
spermatid development GO:0007286 4 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
protein targeting GO:0006605 187 0.013
zymogen activation GO:0031638 70 0.013
chemokine production GO:0032602 32 0.013
regeneration GO:0031099 4 0.013
hormone transport GO:0009914 68 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
positive regulation of jnk cascade GO:0046330 52 0.013
response to axon injury GO:0048678 1 0.013
locomotory behavior GO:0007626 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.013
protein ubiquitination GO:0016567 314 0.012
blastoderm segmentation GO:0007350 2 0.012
t cell tolerance induction GO:0002517 4 0.012
tissue migration GO:0090130 119 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
regulation of growth GO:0040008 165 0.012
response to oxygen levels GO:0070482 100 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
response to radiation GO:0009314 151 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
hormone secretion GO:0046879 65 0.012
positive regulation of t cell proliferation GO:0042102 33 0.012
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.012
mitotic nuclear division GO:0007067 119 0.012
glycoprotein metabolic process GO:0009100 110 0.012
lymphocyte mediated immunity GO:0002449 48 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
cardiac muscle contraction GO:0060048 34 0.012

SIGLEC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.028
immune system disease DOID:2914 155 0.023
inherited metabolic disorder DOID:655 242 0.023
sensory system disease DOID:0050155 203 0.020
eye and adnexa disease DOID:1492 150 0.020
nervous system disease DOID:863 431 0.020
eye disease DOID:5614 149 0.020
retinal disease DOID:5679 118 0.017
disease of cellular proliferation DOID:14566 174 0.016
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.015
retinal degeneration DOID:8466 89 0.014
disease of mental health DOID:150 70 0.013