Homo sapiens

8 known processes

SPTLC1

serine palmitoyltransferase, long chain base subunit 1

(Aliases: SPTI,LBC1,HSAN,MGC14645,LCB1,SPT1,HSN1,HSAN1)

SPTLC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 292 0.262
post embryonic development GO:0009791 2 0.247
Worm
vesicle mediated transport GO:0016192 371 0.229
organophosphate catabolic process GO:0046434 430 0.136
divalent inorganic cation homeostasis GO:0072507 136 0.116
purine nucleoside triphosphate metabolic process GO:0009144 412 0.108
single organism membrane organization GO:0044802 268 0.106
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.102
vacuole organization GO:0007033 44 0.100
endosomal transport GO:0016197 129 0.094
nucleoside phosphate catabolic process GO:1901292 412 0.089
intracellular protein transport GO:0006886 270 0.086
positive regulation of cellular component organization GO:0051130 376 0.081
endomembrane system organization GO:0010256 196 0.079
ribonucleoside triphosphate metabolic process GO:0009199 412 0.079
ribonucleoside catabolic process GO:0042454 406 0.074
endocytosis GO:0006897 159 0.073
nucleoside triphosphate catabolic process GO:0009143 394 0.073
single organism cellular localization GO:1902580 332 0.071
growth GO:0040007 202 0.071
nervous system development GO:0007399 293 0.070
cytoplasmic transport GO:0016482 379 0.070
nucleoside catabolic process GO:0009164 408 0.067
cell adhesion GO:0007155 325 0.066
purine ribonucleoside metabolic process GO:0046128 437 0.065
secretion GO:0046903 254 0.062
nucleoside triphosphate metabolic process GO:0009141 422 0.062
purine nucleoside triphosphate catabolic process GO:0009146 392 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.059
ribonucleoside triphosphate catabolic process GO:0009203 391 0.057
single organism membrane fusion GO:0044801 37 0.055
glycosyl compound catabolic process GO:1901658 413 0.055
purine nucleotide catabolic process GO:0006195 405 0.055
biological adhesion GO:0022610 331 0.053
negative regulation of cellular component organization GO:0051129 235 0.053
protein localization to membrane GO:0072657 160 0.052
cellular homeostasis GO:0019725 196 0.052
protein catabolic process GO:0030163 325 0.052
cell fate determination GO:0001709 3 0.052
ribonucleotide catabolic process GO:0009261 405 0.052
cell development GO:0048468 328 0.051
cellular component morphogenesis GO:0032989 314 0.051
establishment of organelle localization GO:0051656 59 0.051
regulation of vesicle mediated transport GO:0060627 130 0.050
purine nucleoside catabolic process GO:0006152 398 0.049
neuromuscular junction development GO:0007528 3 0.048
vesicle organization GO:0016050 62 0.048
regulation of protein localization GO:0032880 296 0.047
purine ribonucleotide catabolic process GO:0009154 404 0.046
positive regulation of developmental process GO:0051094 314 0.046
glycoprotein biosynthetic process GO:0009101 91 0.044
organophosphate biosynthetic process GO:0090407 163 0.044
Mouse
oogenesis GO:0048477 2 0.044
protein localization to organelle GO:0033365 280 0.044
cell activation GO:0001775 213 0.043
cation homeostasis GO:0055080 189 0.041
cell cell signaling GO:0007267 155 0.041
anatomical structure formation involved in morphogenesis GO:0048646 284 0.040
locomotory behavior GO:0007626 1 0.040
neurotransmitter secretion GO:0007269 4 0.037
plasma membrane organization GO:0007009 115 0.036
cell growth GO:0016049 160 0.036
ion homeostasis GO:0050801 230 0.036
organelle assembly GO:0070925 176 0.035
calcium ion homeostasis GO:0055074 122 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
nitrogen compound transport GO:0071705 191 0.034
regulation of growth GO:0040008 165 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
cellular divalent inorganic cation homeostasis GO:0072503 128 0.033
actin filament based process GO:0030029 224 0.033
metal ion homeostasis GO:0055065 169 0.033
purine containing compound catabolic process GO:0072523 411 0.033
cellular ion homeostasis GO:0006873 168 0.031
actin cytoskeleton organization GO:0030036 207 0.031
gtp catabolic process GO:0006184 237 0.030
cellular chemical homeostasis GO:0055082 180 0.030
exocytosis GO:0006887 71 0.030
regulation of cell growth GO:0001558 135 0.030
organelle fusion GO:0048284 36 0.029
immune response GO:0006955 307 0.029
nucleotide catabolic process GO:0009166 408 0.028
secretion by cell GO:0032940 226 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
rab protein signal transduction GO:0032482 4 0.027
multicellular organismal aging GO:0010259 3 0.027
regulation of cell projection organization GO:0031344 107 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
cation transport GO:0006812 331 0.026
atp catabolic process GO:0006200 157 0.025
cellular protein complex assembly GO:0043623 188 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
guanosine containing compound metabolic process GO:1901068 244 0.024
regulation of transferase activity GO:0051338 355 0.024
cell projection organization GO:0030030 252 0.024
atp metabolic process GO:0046034 176 0.024
protein maturation GO:0051604 233 0.024
chemical homeostasis GO:0048878 306 0.024
positive regulation of cellular component movement GO:0051272 181 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
golgi vesicle transport GO:0048193 80 0.023
organelle localization GO:0051640 84 0.023
maintenance of location GO:0051235 112 0.023
determination of adult lifespan GO:0008340 2 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
mapk cascade GO:0000165 288 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
cellular protein catabolic process GO:0044257 261 0.022
segmentation GO:0035282 4 0.022
macromolecule glycosylation GO:0043413 63 0.021
cellular calcium ion homeostasis GO:0006874 117 0.021
leukocyte mediated immunity GO:0002443 59 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.021
lipid biosynthetic process GO:0008610 177 0.021
Mouse
cell morphogenesis GO:0000902 296 0.021
nucleoside monophosphate catabolic process GO:0009125 159 0.021
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.021
Worm
female gamete generation GO:0007292 2 0.020
positive regulation of cell growth GO:0030307 48 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
response to starvation GO:0042594 59 0.020
oocyte development GO:0048599 1 0.020
protein localization to plasma membrane GO:0072659 93 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
oocyte differentiation GO:0009994 2 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
alcohol metabolic process GO:0006066 114 0.019
Mouse
negative regulation of catalytic activity GO:0043086 335 0.019
regulation of cell development GO:0060284 161 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.019
neurogenesis GO:0022008 169 0.019
morphogenesis of embryonic epithelium GO:0016331 4 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
cellular cation homeostasis GO:0030003 163 0.018
cholesterol transport GO:0030301 39 0.018
vacuolar transport GO:0007034 34 0.018
guanosine containing compound catabolic process GO:1901069 239 0.017
positive regulation of transport GO:0051050 336 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
positive regulation of growth GO:0045927 58 0.017
regulation of protein transport GO:0051223 213 0.017
cyclic purine nucleotide metabolic process GO:0052652 60 0.017
positive regulation of cell cycle GO:0045787 140 0.017
protein targeting GO:0006605 187 0.017
leukocyte activation GO:0045321 164 0.017
embryo development GO:0009790 123 0.017
Worm
skeletal system development GO:0001501 79 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
regulation of neuron differentiation GO:0045664 70 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
tissue morphogenesis GO:0048729 96 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
carbohydrate metabolic process GO:0005975 207 0.016
cellular component disassembly GO:0022411 92 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.015
negative regulation of transport GO:0051051 176 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
spermatid differentiation GO:0048515 4 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
gtp metabolic process GO:0046039 239 0.015
regulation of cellular response to stress GO:0080135 244 0.015
positive regulation of axon extension GO:0045773 4 0.015
response to extracellular stimulus GO:0009991 85 0.015
establishment of protein localization to plasma membrane GO:0090002 68 0.015
tripartite regional subdivision GO:0007351 2 0.015
regulation of mapk cascade GO:0043408 262 0.014
morphogenesis of an epithelium GO:0002009 60 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
cellular response to nutrient levels GO:0031669 69 0.014
protein palmitoylation GO:0018345 19 0.014
positive regulation of catabolic process GO:0009896 310 0.014
defense response GO:0006952 315 0.014
regulation of kinase activity GO:0043549 314 0.014
microtubule based process GO:0007017 210 0.014
anterior posterior axis specification GO:0009948 2 0.014
cellular response to starvation GO:0009267 58 0.013
synaptic vesicle recycling GO:0036465 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
cell division GO:0051301 168 0.013
stem cell division GO:0017145 2 0.013
positive regulation of secretion GO:0051047 116 0.013
regulation of cellular component size GO:0032535 82 0.013
central nervous system development GO:0007417 123 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
ras protein signal transduction GO:0007265 73 0.013
notch signaling pathway GO:0007219 31 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
response to nutrient levels GO:0031667 81 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
regulation of neuron projection development GO:0010975 57 0.013
positive regulation of transferase activity GO:0051347 227 0.013
cell cycle phase transition GO:0044770 173 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
regulation of secretion GO:0051046 194 0.012
regulation of anatomical structure size GO:0090066 101 0.012
spermatid development GO:0007286 4 0.012
behavior GO:0007610 112 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
neuron projection development GO:0031175 106 0.012
protein glycosylation GO:0006486 62 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
protein lipidation GO:0006497 33 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of cell motility GO:2000145 299 0.012
negative regulation of cell cycle GO:0045786 193 0.012
protein depolymerization GO:0051261 30 0.012
positive regulation of dendrite morphogenesis GO:0050775 3 0.012
metal ion transport GO:0030001 272 0.012
regulation of cytoskeleton organization GO:0051493 177 0.011
blastoderm segmentation GO:0007350 2 0.011
negative regulation of organelle organization GO:0010639 126 0.011
negative regulation of secretion by cell GO:1903531 52 0.011
positive regulation of neuron differentiation GO:0045666 40 0.011
regulation of oocyte development GO:0060281 1 0.011
regulation of cellular component movement GO:0051270 334 0.011
response to external biotic stimulus GO:0043207 261 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
cell projection assembly GO:0030031 126 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
immune effector process GO:0002252 159 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
dephosphorylation GO:0016311 209 0.011
regulation of endocytosis GO:0030100 72 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
response to biotic stimulus GO:0009607 276 0.011
positive regulation of exocytosis GO:0045921 35 0.011
generation of neurons GO:0048699 152 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
regulation of immune response GO:0050776 201 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
post golgi vesicle mediated transport GO:0006892 36 0.011
axon cargo transport GO:0008088 2 0.011
organelle inheritance GO:0048308 2 0.011
macroautophagy GO:0016236 39 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
regulation of neurogenesis GO:0050767 82 0.010
neuroblast proliferation GO:0007405 4 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
organic hydroxy compound transport GO:0015850 63 0.010
cytokine production GO:0001816 247 0.010
regulation of cell differentiation GO:0045595 393 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
positive regulation of endocytosis GO:0045807 42 0.010
positive regulation of organelle organization GO:0010638 195 0.010
lipid transport GO:0006869 90 0.010
membrane fusion GO:0061025 43 0.010
regulation of cell cycle GO:0051726 393 0.010
lipid localization GO:0010876 106 0.010
response to other organism GO:0051707 261 0.010
cell projection morphogenesis GO:0048858 129 0.010

SPTLC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.027
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.025
central nervous system disease DOID:331 186 0.018
neurodegenerative disease DOID:1289 102 0.018
nervous system disease DOID:863 431 0.018
disease of metabolism DOID:0014667 295 0.016
bone disease DOID:0080001 88 0.013
connective tissue disease DOID:65 109 0.013
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
immune system disease DOID:2914 155 0.012
anemia DOID:2355 55 0.012
hematopoietic system disease DOID:74 100 0.012
neuropathy DOID:870 52 0.002
peripheral neuropathy DOID:0060053 12 0.001
hereditary sensory neuropathy DOID:0050548 12 0.001