|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.815
|
|
|
|
lipid translocation
|
GO:0034204 |
2 |
0.352
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.286
|
|
|
|
phospholipid translocation
|
GO:0045332 |
2 |
0.258
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.220
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.215
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.204
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.174
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.173
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.161
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.147
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.145
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.142
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.138
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.138
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.135
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.130
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.129
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.129
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.128
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.123
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.123
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.121
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.119
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.118
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.117
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.117
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.116
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.112
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.109
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.107
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.103
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.103
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.101
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.100
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.100
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.098
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.097
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.095
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.095
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.094
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.093
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.092
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.091
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.088
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.087
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.085
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.084
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.084
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.083
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.081
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.080
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.080
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.077
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.075
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.073
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.073
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.073
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.073
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.072
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.071
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.071
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.070
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.068
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.068
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.068
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.068
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.068
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.068
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.068
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.067
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.067
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.064
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.063
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.062
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.062
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.061
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.061
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.060
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.060
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.060
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.060
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.059
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.059
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.059
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.059
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.058
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.058
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.058
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.058
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.057
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.056
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.056
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.056
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.056
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.056
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.056
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.055
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.055
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.055
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.054
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.054
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.053
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.053
|
|
|
|
phospholipid transport
|
GO:0015914 |
23 |
0.053
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.053
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.053
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.052
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.051
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.051
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.050
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.050
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.050
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.050
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.050
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.050
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.048
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.048
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.048
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.046
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.046
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.046
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.046
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.046
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.046
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.046
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.046
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.045
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.045
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.045
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.044
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.044
|
Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.043
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.043
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.042
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.042
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.042
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.042
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.041
|
|
|
|
system process
|
GO:0003008 |
349 |
0.041
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.041
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.041
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.041
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.040
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.040
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.040
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.039
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.039
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.039
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.038
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.038
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.038
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.038
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.038
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.038
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.038
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.038
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.038
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.036
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.036
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.036
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.036
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.036
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.035
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.035
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.035
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.035
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.035
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.035
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.035
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.035
|
Fly |
|
|
mating
|
GO:0007618 |
1 |
0.035
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.035
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.034
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.034
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.034
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.034
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.034
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.034
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.033
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.033
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.033
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.033
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.033
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.033
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.033
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.033
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.033
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.033
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.032
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.032
|
Fly |
|
|
nerve development
|
GO:0021675 |
4 |
0.032
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.032
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.032
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.032
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.032
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.032
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.032
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.032
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.032
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.031
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.031
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.031
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.031
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.031
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.030
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.030
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.030
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.030
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.030
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.030
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.030
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.030
|
Fly |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.029
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.029
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.029
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.029
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.029
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.029
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.029
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.028
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.028
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.028
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.028
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.028
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.028
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.028
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.028
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.028
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.027
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.027
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.027
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.027
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.027
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.027
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.027
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.026
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.026
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.026
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.026
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.026
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.026
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.026
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.026
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.026
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.026
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.025
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.025
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.025
|
|
|
|
copulation
|
GO:0007620 |
1 |
0.025
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.025
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.025
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.025
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.025
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.025
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.025
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.024
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.024
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.024
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.024
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.024
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.024
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.024
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.023
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.023
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.023
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.023
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.023
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.023
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.023
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.023
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.023
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.023
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.023
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.023
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.023
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.022
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.022
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.022
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.022
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.022
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.022
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.022
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.022
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.022
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.022
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.022
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.022
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.022
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.022
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.022
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.021
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.021
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.021
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.021
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.021
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.021
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.021
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.021
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.021
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.021
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.021
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.021
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.021
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.021
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.021
|
|
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.020
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.020
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.020
|
Human |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.020
|
Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.020
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.020
|
|
|
|
organophosphate ester transport
|
GO:0015748 |
32 |
0.020
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.020
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.020
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.020
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.020
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.020
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.020
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.020
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.020
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.020
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.020
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.019
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.019
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.019
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.019
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.019
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.019
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.019
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.019
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.019
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.019
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.019
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.019
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.019
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.019
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.018
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.018
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.018
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.018
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.018
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.018
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.018
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.018
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.018
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.018
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.018
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.018
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.018
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.018
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.018
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.018
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.018
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.017
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.017
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.017
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.017
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.017
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.017
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.017
|
Fly |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.017
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.017
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.017
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.017
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.017
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.017
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.017
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.017
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.017
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.017
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.016
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.016
|
|
|
|
growth
|
GO:0040007 |
202 |
0.016
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.016
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.016
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.016
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.016
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.016
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.016
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.016
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.016
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.016
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.016
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.016
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.016
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.016
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.016
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.016
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.016
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.016
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.015
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.015
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.015
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.015
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.015
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.015
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.015
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.015
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.015
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.015
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.015
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.015
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.015
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.015
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.015
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.015
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.015
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.015
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.015
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.015
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.015
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.015
|
Human |
|
|
response to virus
|
GO:0009615 |
126 |
0.015
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.015
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.015
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.015
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.015
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.014
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.014
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.014
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.014
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.014
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.014
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.014
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.014
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.014
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
27 |
0.014
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.014
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.014
|
|
|
|
insemination
|
GO:0007320 |
1 |
0.014
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.014
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.014
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.014
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.014
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.014
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.014
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.014
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.014
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.014
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.014
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.014
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.014
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.014
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.014
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.014
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.014
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.014
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.014
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.013
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.013
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.013
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.013
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.013
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.013
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.013
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.013
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.013
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.013
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.013
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.013
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.013
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.013
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.013
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.013
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.013
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.013
|
|
