|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.914
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.751
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
4 |
0.671
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.650
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.610
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.601
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.587
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.531
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.510
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.508
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.489
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.474
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.412
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.404
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.403
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.399
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.395
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.366
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.336
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.331
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.318
|
Human Fly |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.311
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.294
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.290
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.289
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.285
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.283
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.283
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.277
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.268
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.267
|
Fly |
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.259
|
Human |
|
|
t cell activation
|
GO:0042110 |
99 |
0.254
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.252
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.250
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.249
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.244
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.240
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.239
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.232
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.222
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.221
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
7 |
0.220
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.214
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.205
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.205
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.204
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.204
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
2 |
0.200
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.199
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.196
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.192
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.192
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.181
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.178
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.175
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.172
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.170
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.169
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.167
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.166
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.165
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.163
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.160
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.158
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.157
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.155
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.152
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.150
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.142
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.141
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.139
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.137
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.132
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.132
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.132
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.130
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.129
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.129
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.129
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.127
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
19 |
0.126
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.125
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.125
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.124
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.122
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.122
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.121
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.115
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.114
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.113
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.113
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.110
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.108
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.106
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.105
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.105
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.104
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.104
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.103
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.103
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.101
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.099
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.098
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.098
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.095
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.094
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
23 |
0.092
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.090
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.087
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.087
|
Fly |
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.086
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.085
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.085
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.084
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.082
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.082
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.082
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.081
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.081
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
15 |
0.080
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
10 |
0.080
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.079
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.078
|
Fly |
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.078
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.078
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.078
|
Yeast |
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.076
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.075
|
|
|
|
negative regulation of mononuclear cell proliferation
|
GO:0032945 |
15 |
0.075
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.074
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
6 |
0.074
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.074
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.073
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.072
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.069
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.068
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.068
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.067
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.066
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.065
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.065
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.065
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.064
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.063
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.062
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.062
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.061
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.061
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.060
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.059
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
6 |
0.059
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.058
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.057
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
8 |
0.056
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.056
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.055
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.055
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.055
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.055
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.054
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.053
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.053
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.051
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.051
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.051
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.051
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.051
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
7 |
0.050
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.050
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.049
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.049
|
Human Yeast |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.049
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.048
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.048
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.047
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.046
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.046
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.045
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.045
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.045
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.044
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.044
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.044
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.043
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.043
|
Fly |
|
|
protein secretion
|
GO:0009306 |
98 |
0.042
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.041
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.041
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.040
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.040
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.039
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.039
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.039
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.038
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.038
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.038
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.038
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.038
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.038
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.037
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.037
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.037
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.037
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.037
|
Fly |
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.037
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.036
|
Fly |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.036
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.036
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.036
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.035
|
Human |
|
|
associative learning
|
GO:0008306 |
1 |
0.035
|
Fly |
|
|
positive regulation of astrocyte chemotaxis
|
GO:2000464 |
1 |
0.034
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.034
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.033
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.033
|
Fly |
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.033
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.033
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.033
|
Human |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.033
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.033
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.032
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.031
|
Fly |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.031
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.031
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.031
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.030
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.030
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.030
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.030
|
|
|
|
regulation of astrocyte chemotaxis
|
GO:2000458 |
1 |
0.030
|
|
|
|
immunoglobulin production
|
GO:0002377 |
12 |
0.030
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.030
|
Human Fly |
|
|
viral process
|
GO:0016032 |
146 |
0.029
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.029
|
|
|
|
positive regulation of early endosome to late endosome transport
|
GO:2000643 |
3 |
0.029
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.029
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.029
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.029
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.028
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.028
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.028
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.028
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.028
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.028
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.028
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.027
|
Fly |
|
|
positive regulation of dna recombination
|
GO:0045911 |
3 |
0.027
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.027
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.027
|
Fly |
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.027
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.027
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.027
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.027
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.026
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.026
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.026
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.026
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.026
|
Yeast |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.026
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.026
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.026
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.026
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.026
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.025
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.025
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.025
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.025
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
Fly |
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.025
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.025
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.025
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.025
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.025
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.024
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.024
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.024
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.024
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.024
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.024
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.024
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.024
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.024
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.024
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.024
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
7 |
0.024
|
|
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.024
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.023
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.023
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.023
|
Yeast Fly |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.023
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.023
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.023
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.023
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.023
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.023
|
|
|
|
negative regulation of cd8 positive alpha beta t cell activation
|
GO:2001186 |
1 |
0.023
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.022
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.022
|
|
|
|
t cell costimulation
|
GO:0031295 |
7 |
0.022
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.022
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.022
|
|
|
|
chemokine c c motif ligand 19 signaling pathway
|
GO:0038115 |
1 |
0.022
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.022
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
5 |
0.022
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.021
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.021
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.021
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.021
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.021
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.021
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.021
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.021
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.021
|
Yeast Fly |
|
|
cell killing
|
GO:0001906 |
34 |
0.020
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.020
|
Yeast |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.020
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.020
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.020
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.020
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.020
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.020
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.020
|
|
|
|
multi organism membrane organization
|
GO:0044803 |
12 |
0.020
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.020
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.020
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.020
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.020
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.019
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.019
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.019
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.019
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.019
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.019
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.019
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.018
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.018
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.018
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.018
|
Fly |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.018
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.018
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.018
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.018
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.018
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.018
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.018
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.018
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.018
|
Human |
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.018
|
|
|
|
response to testosterone
|
GO:0033574 |
1 |
0.018
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.018
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.017
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.017
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.017
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.017
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.017
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.017
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.017
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
10 |
0.017
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.017
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.017
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.017
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.017
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.017
|
Human |
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.017
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
7 |
0.017
|
|
|
|
toll signaling pathway
|
GO:0008063 |
2 |
0.017
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.016
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.016
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.016
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.016
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.016
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.016
|
Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.016
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.016
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.016
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.016
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.016
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.016
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.016
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.016
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.016
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.016
|
Fly |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.015
|
Fly |
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.015
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.015
|
Fly |
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.015
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.015
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.015
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.015
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.015
|
Fly |
|
|
protein alkylation
|
GO:0008213 |
74 |
0.015
|
|
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.015
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.015
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.015
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.015
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.015
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.015
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.015
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.015
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.015
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.015
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.015
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.015
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.015
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.015
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.015
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.015
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.014
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.014
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.014
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.014
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.014
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.014
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.014
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.014
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.014
|
Human |
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
6 |
0.014
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.014
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.014
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.014
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.014
|
|
|
|
intralumenal vesicle formation
|
GO:0070676 |
1 |
0.014
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.014
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.014
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.014
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.014
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.014
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.014
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.014
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.014
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.014
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.014
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.014
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.013
|
Fly |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.013
|
Human |
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.013
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.013
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.013
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.013
|
|
|
|
memory
|
GO:0007613 |
3 |
0.013
|
Fly |
|
|
methylation
|
GO:0032259 |
106 |
0.013
|
|
|
|
system process
|
GO:0003008 |
349 |
0.013
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.013
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.013
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.013
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.013
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.013
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.013
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.013
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.013
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.013
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.013
|
Human |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.013
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.013
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.013
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
6 |
0.013
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.013
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.013
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.013
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.013
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.013
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.013
|
Fly |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.013
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.013
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.013
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.012
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.012
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.012
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.012
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.012
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.012
|
Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.012
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.012
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.012
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.012
|
|
