Homo sapiens

113 known processes

KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

(Aliases: ERG1,HERG,Kv11.1,HERG1,SQT1,LQT2)

KCNH2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic cation transmembrane transport GO:0098662 194 0.533
transmembrane transport GO:0055085 399 0.335
inorganic ion transmembrane transport GO:0098660 231 0.305
cation transmembrane transport GO:0098655 238 0.287
ion transmembrane transport GO:0034220 338 0.171
system process GO:0003008 349 0.162
cell development GO:0048468 328 0.159
cation transport GO:0006812 331 0.155
metal ion homeostasis GO:0055065 169 0.127
monovalent inorganic cation transport GO:0015672 128 0.123
nervous system development GO:0007399 293 0.112
Rat
regulation of cellular ketone metabolic process GO:0010565 50 0.110
positive regulation of transport GO:0051050 336 0.104
metal ion transport GO:0030001 272 0.100
cellular amino acid metabolic process GO:0006520 116 0.099
cellular response to endogenous stimulus GO:0071495 336 0.097
ion homeostasis GO:0050801 230 0.097
cellular chemical homeostasis GO:0055082 180 0.096
ribonucleoside triphosphate metabolic process GO:0009199 412 0.093
muscle contraction GO:0006936 73 0.092
amine metabolic process GO:0009308 44 0.089
cellular amine metabolic process GO:0044106 41 0.088
post embryonic development GO:0009791 2 0.087
regulation of cellular amino acid metabolic process GO:0006521 6 0.087
regulation of cell differentiation GO:0045595 393 0.084
regulation of cellular component movement GO:0051270 334 0.084
oxidation reduction process GO:0055114 396 0.083
purine ribonucleoside metabolic process GO:0046128 437 0.082
actin filament based process GO:0030029 224 0.081
regulation of anatomical structure morphogenesis GO:0022603 286 0.081
cellular component morphogenesis GO:0032989 314 0.081
cellular potassium ion transport GO:0071804 60 0.080
response to oxygen containing compound GO:1901700 369 0.080
nucleoside triphosphate metabolic process GO:0009141 422 0.078
regulation of cellular amine metabolic process GO:0033238 11 0.078
negative regulation of multicellular organismal process GO:0051241 317 0.077
single organism membrane organization GO:0044802 268 0.076
cellular homeostasis GO:0019725 196 0.074
regulation of ion transmembrane transport GO:0034765 132 0.074
cellular ion homeostasis GO:0006873 168 0.073
response to abiotic stimulus GO:0009628 336 0.072
cell morphogenesis GO:0000902 296 0.071
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
regulation of secretion by cell GO:1903530 177 0.070
regulation of cell cycle GO:0051726 393 0.070
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.069
chemical homeostasis GO:0048878 306 0.067
cellular ketone metabolic process GO:0042180 80 0.066
regulation of ion transport GO:0043269 189 0.066
spinal cord development GO:0021510 4 0.065
Rat
positive regulation of phosphorylation GO:0042327 394 0.065
purine nucleoside triphosphate metabolic process GO:0009144 412 0.064
cellular metal ion homeostasis GO:0006875 146 0.064
organophosphate catabolic process GO:0046434 430 0.064
neuron differentiation GO:0030182 138 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.062
generation of neurons GO:0048699 152 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.060
membrane organization GO:0061024 292 0.060
single organism cellular localization GO:1902580 332 0.059
cardiovascular system development GO:0072358 262 0.058
negative regulation of protein metabolic process GO:0051248 391 0.057
regulation of transmembrane transport GO:0034762 139 0.056
cation homeostasis GO:0055080 189 0.056
ribonucleotide catabolic process GO:0009261 405 0.056
nucleoside triphosphate catabolic process GO:0009143 394 0.056
organonitrogen compound biosynthetic process GO:1901566 200 0.056
positive regulation of protein phosphorylation GO:0001934 313 0.055
nucleoside catabolic process GO:0009164 408 0.055
blood circulation GO:0008015 113 0.054
cytoplasmic transport GO:0016482 379 0.054
regulation of protein localization GO:0032880 296 0.053
nucleotide catabolic process GO:0009166 408 0.053
purine nucleotide catabolic process GO:0006195 405 0.053
regulation of establishment of protein localization GO:0070201 242 0.052
positive regulation of ion transport GO:0043270 87 0.051
regulation of system process GO:0044057 101 0.050
purine nucleoside catabolic process GO:0006152 398 0.050
potassium ion transmembrane transport GO:0071805 60 0.050
immune system development GO:0002520 195 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.049
intracellular protein transport GO:0006886 270 0.049
muscle system process GO:0003012 81 0.048
regulation of secretion GO:0051046 194 0.048
regulation of transferase activity GO:0051338 355 0.047
purine ribonucleotide catabolic process GO:0009154 404 0.047
purine containing compound catabolic process GO:0072523 411 0.047
cell projection organization GO:0030030 252 0.047
purine ribonucleoside catabolic process GO:0046130 398 0.047
cardiac muscle cell contraction GO:0086003 4 0.047
secretion GO:0046903 254 0.047
purine nucleoside triphosphate catabolic process GO:0009146 392 0.047
circulatory system development GO:0072359 262 0.046
regulation of kinase activity GO:0043549 314 0.046
regulation of hormone levels GO:0010817 125 0.046
regulation of purine nucleotide metabolic process GO:1900542 264 0.046
locomotory behavior GO:0007626 1 0.046
nitrogen compound transport GO:0071705 191 0.045
anion transport GO:0006820 161 0.045
hindbrain development GO:0030902 3 0.044
regulation of locomotion GO:0040012 329 0.044
positive regulation of cellular component organization GO:0051130 376 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.044
vesicle mediated transport GO:0016192 371 0.044
cardiac muscle contraction GO:0060048 34 0.044
multicellular organismal aging GO:0010259 3 0.044
potassium ion transport GO:0006813 62 0.043
memory GO:0007613 3 0.043
cell adhesion GO:0007155 325 0.043
cellular lipid metabolic process GO:0044255 303 0.043
oogenesis GO:0048477 2 0.043
monocarboxylic acid metabolic process GO:0032787 185 0.043
cell cell signaling GO:0007267 155 0.042
positive regulation of developmental process GO:0051094 314 0.042
ribonucleoside catabolic process GO:0042454 406 0.042
neuromuscular junction development GO:0007528 3 0.042
response to growth factor GO:0070848 205 0.041
lipid metabolic process GO:0006629 381 0.041
regulation of cell motility GO:2000145 299 0.041
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
positive regulation of catabolic process GO:0009896 310 0.040
cell part morphogenesis GO:0032990 137 0.040
negative regulation of catalytic activity GO:0043086 335 0.040
female gamete generation GO:0007292 2 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
cell differentiation in spinal cord GO:0021515 1 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.040
actin filament based movement GO:0030048 17 0.039
nucleoside phosphate catabolic process GO:1901292 412 0.039
biological adhesion GO:0022610 331 0.039
cellular divalent inorganic cation homeostasis GO:0072503 128 0.039
negative regulation of developmental process GO:0051093 247 0.039
sodium ion transmembrane transport GO:0035725 59 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
negative regulation of cell differentiation GO:0045596 171 0.039
mitotic cell cycle process GO:1903047 286 0.039
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
regulation of cell migration GO:0030334 289 0.038
regulation of intracellular transport GO:0032386 195 0.038
regulation of protein kinase activity GO:0045859 289 0.037
regulation of membrane potential GO:0042391 95 0.037
cellular cation homeostasis GO:0030003 163 0.037
negative regulation of synaptic transmission GO:0050805 2 0.037
positive regulation of secretion GO:0051047 116 0.036
cell morphogenesis involved in differentiation GO:0000904 144 0.036
protein localization to membrane GO:0072657 160 0.036
neuron fate commitment GO:0048663 2 0.035
heart development GO:0007507 95 0.035
neurogenesis GO:0022008 169 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
cellular response to oxygen containing compound GO:1901701 276 0.035
divalent inorganic cation homeostasis GO:0072507 136 0.035
cellular response to dna damage stimulus GO:0006974 379 0.035
endomembrane system organization GO:0010256 196 0.035
secretion by cell GO:0032940 226 0.035
positive regulation of cell proliferation GO:0008284 301 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
cell fate determination GO:0001709 3 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
negative regulation of transport GO:0051051 176 0.034
hemopoiesis GO:0030097 180 0.033
segmentation GO:0035282 4 0.033
striated muscle contraction GO:0006941 52 0.033
regulation of cell development GO:0060284 161 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.033
carbohydrate derivative biosynthetic process GO:1901137 207 0.033
carbohydrate metabolic process GO:0005975 207 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.032
regulation of cell cycle process GO:0010564 266 0.032
Human
negative regulation of phosphorylation GO:0042326 174 0.032
regulation of transporter activity GO:0032409 82 0.032
cardiac right ventricle morphogenesis GO:0003215 3 0.032
determination of adult lifespan GO:0008340 2 0.031
mapk cascade GO:0000165 288 0.031
ribonucleoside monophosphate metabolic process GO:0009161 187 0.031
regulation of metal ion transport GO:0010959 120 0.031
negative regulation of cell proliferation GO:0008285 228 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.031
positive regulation of kinase activity GO:0033674 204 0.031
tube development GO:0035295 125 0.031
purine nucleoside monophosphate metabolic process GO:0009126 186 0.031
divalent inorganic cation transport GO:0072511 158 0.030
cellular response to growth factor stimulus GO:0071363 197 0.030
motor neuron axon guidance GO:0008045 2 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
action potential GO:0001508 34 0.030
regulation of cell morphogenesis GO:0022604 153 0.030
multicellular organismal signaling GO:0035637 34 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
atp metabolic process GO:0046034 176 0.029
central nervous system development GO:0007417 123 0.029
Rat
calcium ion homeostasis GO:0055074 122 0.029
neurotransmitter secretion GO:0007269 4 0.029
sodium ion transport GO:0006814 61 0.029
organ morphogenesis GO:0009887 147 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
protein localization to organelle GO:0033365 280 0.029
regulation of protein transport GO:0051223 213 0.029
negative regulation of protein phosphorylation GO:0001933 140 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.029
negative regulation of protein modification process GO:0031400 200 0.029
calcium ion transport GO:0006816 147 0.029
regulation of ion transmembrane transporter activity GO:0032412 72 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
positive regulation of transferase activity GO:0051347 227 0.028
mitotic cell cycle GO:0000278 326 0.028
Human
myeloid cell differentiation GO:0030099 117 0.028
positive regulation of protein kinase activity GO:0045860 190 0.028
erythrocyte development GO:0048821 3 0.028
regulation of neural precursor cell proliferation GO:2000177 4 0.028
ras protein signal transduction GO:0007265 73 0.028
epithelium development GO:0060429 227 0.027
regulation of muscle system process GO:0090257 53 0.027
kidney development GO:0001822 53 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
reactive oxygen species biosynthetic process GO:1903409 4 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.026
gtp catabolic process GO:0006184 237 0.026
small molecule biosynthetic process GO:0044283 157 0.026
nerve development GO:0021675 4 0.026
fatty acid metabolic process GO:0006631 115 0.026
positive regulation of cell death GO:0010942 263 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
regulation of cellular response to stress GO:0080135 244 0.026
neuroblast proliferation GO:0007405 4 0.026
associative learning GO:0008306 1 0.026
neuron development GO:0048666 113 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
metencephalon development GO:0022037 2 0.025
epithelial cell differentiation GO:0030855 141 0.025
negative regulation of gliogenesis GO:0014014 3 0.025
actin cytoskeleton organization GO:0030036 207 0.025
lipid biosynthetic process GO:0008610 177 0.025
neurological system process GO:0050877 163 0.025
Fly
positive regulation of cell differentiation GO:0045597 211 0.025
response to wounding GO:0009611 168 0.025
chromatin organization GO:0006325 351 0.025
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
regulation of response to external stimulus GO:0032101 222 0.024
regulation of neurotransmitter secretion GO:0046928 3 0.024
positive regulation of secretion by cell GO:1903532 108 0.024
cytosolic calcium ion homeostasis GO:0051480 89 0.024
cytokine production GO:0001816 247 0.024
negative regulation of locomotion GO:0040013 118 0.024
response to decreased oxygen levels GO:0036293 96 0.024
tissue morphogenesis GO:0048729 96 0.024
regulation of cytokine production GO:0001817 232 0.024
guanosine containing compound metabolic process GO:1901068 244 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
cranial nerve development GO:0021545 4 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
regulation of mapk cascade GO:0043408 262 0.024
neuron projection development GO:0031175 106 0.024
cell division GO:0051301 168 0.023
growth GO:0040007 202 0.023
cellular response to nitrogen compound GO:1901699 144 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
regulation of synaptic plasticity GO:0048167 3 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
Human
positive regulation of cell motility GO:2000147 177 0.023
calcium ion transmembrane transport GO:0070588 76 0.023
regulation of proteolysis GO:0030162 293 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.022
epithelium migration GO:0090132 119 0.022
blastoderm segmentation GO:0007350 2 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
circulatory system process GO:0003013 113 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
actin mediated cell contraction GO:0070252 12 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
ventral spinal cord development GO:0021517 1 0.022
chromatin modification GO:0016568 298 0.022
regulation of actin filament based process GO:0032970 141 0.022
regulation of muscle contraction GO:0006937 45 0.022
response to nitrogen compound GO:1901698 184 0.022
oocyte differentiation GO:0009994 2 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
anion transmembrane transport GO:0098656 76 0.021
regulation of heart contraction GO:0008016 50 0.021
sex determination GO:0007530 3 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
response to organonitrogen compound GO:0010243 156 0.021
response to oxygen levels GO:0070482 100 0.021
microtubule based process GO:0007017 210 0.021
regulation of cell growth GO:0001558 135 0.021
heart process GO:0003015 62 0.021
negative regulation of cell death GO:0060548 345 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
positive regulation of locomotion GO:0040017 186 0.021
regulation of intracellular protein transport GO:0033157 123 0.021
vasculature development GO:0001944 181 0.021
plasma membrane organization GO:0007009 115 0.021
divalent metal ion transport GO:0070838 152 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
somatic stem cell maintenance GO:0035019 4 0.021
immune response GO:0006955 307 0.021
protein autophosphorylation GO:0046777 123 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
protein targeting GO:0006605 187 0.021
regulation of homeostatic process GO:0032844 121 0.021
nuclear transport GO:0051169 179 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
regulation of transmembrane transporter activity GO:0022898 74 0.021
hormone secretion GO:0046879 65 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
gas transport GO:0015669 3 0.020
positive regulation of cell cycle GO:0045787 140 0.020
protein localization to plasma membrane GO:0072659 93 0.020
hormone transport GO:0009914 68 0.020
positive regulation of cell development GO:0010720 92 0.020
mitochondrion organization GO:0007005 156 0.020
cerebellum development GO:0021549 2 0.020
glycoprotein metabolic process GO:0009100 110 0.020
hormone metabolic process GO:0042445 61 0.020
embryonic camera type eye formation GO:0060900 2 0.020
signal release GO:0023061 70 0.020
cell cycle phase transition GO:0044770 173 0.020
Human
establishment of protein localization to membrane GO:0090150 121 0.020
head development GO:0060322 108 0.020
Rat
organic hydroxy compound transport GO:0015850 63 0.020
cell growth GO:0016049 160 0.020
embryonic morphogenesis GO:0048598 85 0.020
regulation of neurogenesis GO:0050767 82 0.020
pituitary gland development GO:0021983 2 0.019
regulation of thyroid hormone generation GO:2000609 2 0.019
protein ubiquitination GO:0016567 314 0.019
regulation of nervous system development GO:0051960 88 0.019
organic acid biosynthetic process GO:0016053 97 0.019
protein catabolic process GO:0030163 325 0.019
Worm
regulation of growth GO:0040008 165 0.019
cell activation GO:0001775 213 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.019
positive regulation of immune system process GO:0002684 283 0.019
cellular response to organic cyclic compound GO:0071407 127 0.019
epithelial cell proliferation GO:0050673 128 0.019
regeneration GO:0031099 4 0.018
t cell differentiation in thymus GO:0033077 4 0.018
reactive nitrogen species metabolic process GO:2001057 3 0.018
reproductive process GO:0022414 106 0.018
Worm
positive regulation of cellular component biogenesis GO:0044089 158 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
positive regulation of cell migration GO:0030335 172 0.018
blood vessel development GO:0001568 172 0.018
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.018
protein oligomerization GO:0051259 173 0.018
Rat
coagulation GO:0050817 78 0.018
embryonic camera type eye development GO:0031076 2 0.018
inorganic anion transmembrane transport GO:0098661 47 0.018
synaptic transmission GO:0007268 61 0.018
regulation of protein complex assembly GO:0043254 147 0.018
negative regulation of cell cycle GO:0045786 193 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
regulation of neuron differentiation GO:0045664 70 0.018
regulation of male gonad development GO:2000018 4 0.018
dephosphorylation GO:0016311 209 0.018
anterior posterior axis specification GO:0009948 2 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
regulation of wnt signaling pathway GO:0030111 123 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
ameboidal type cell migration GO:0001667 135 0.017
response to lipid GO:0033993 206 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
cellular protein catabolic process GO:0044257 261 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
negative regulation of cell migration GO:0030336 102 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
peripheral nervous system development GO:0007422 2 0.017
epithelial cell migration GO:0010631 119 0.017
oocyte development GO:0048599 1 0.017
one carbon compound transport GO:0019755 4 0.017
negative regulation of cell motility GO:2000146 104 0.017
detection of stimulus GO:0051606 85 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
adult locomotory behavior GO:0008344 1 0.017
wnt signaling pathway GO:0016055 156 0.017
second messenger mediated signaling GO:0019932 78 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.017
regulation of potassium ion transmembrane transport GO:1901379 20 0.017
transmission of nerve impulse GO:0019226 11 0.017
regulation of body fluid levels GO:0050878 99 0.017
cell projection morphogenesis GO:0048858 129 0.017
response to hypoxia GO:0001666 96 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
endocytosis GO:0006897 159 0.016
dna repair GO:0006281 198 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
glycoprotein biosynthetic process GO:0009101 91 0.016
astrocyte differentiation GO:0048708 4 0.016
peptidyl lysine modification GO:0018205 144 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
urogenital system development GO:0001655 65 0.016
regulation of response to wounding GO:1903034 101 0.016
negative regulation of blood pressure GO:0045776 3 0.016
generation of precursor metabolites and energy GO:0006091 68 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
protein processing GO:0016485 226 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
embryo development GO:0009790 123 0.016
gtp metabolic process GO:0046039 239 0.016
cardiac muscle cell action potential GO:0086001 23 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
Human
regulation of acrosome reaction GO:0060046 4 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
blood vessel morphogenesis GO:0048514 162 0.016
stem cell development GO:0048864 69 0.016
eosinophil differentiation GO:0030222 2 0.016
covalent chromatin modification GO:0016569 254 0.016
inner ear morphogenesis GO:0042472 4 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.016
negative regulation of cytokine production GO:0001818 82 0.016
regulation of multi organism process GO:0043900 157 0.016
response to radiation GO:0009314 151 0.015
sensory perception GO:0007600 103 0.015
Fly
tripartite regional subdivision GO:0007351 2 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
protein maturation GO:0051604 233 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
organelle assembly GO:0070925 176 0.015
wound healing GO:0042060 115 0.015
response to hormone GO:0009725 175 0.015
protein acylation GO:0043543 138 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
regulation of gtpase activity GO:0043087 180 0.015
response to organic cyclic compound GO:0014070 204 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
cell fate commitment involved in pattern specification GO:0060581 1 0.015
regulation of binding GO:0051098 111 0.015
regulation of axon guidance GO:1902667 3 0.015
ventral spinal cord interneuron differentiation GO:0021514 1 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of protein processing GO:0070613 150 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
regulation of cell adhesion GO:0030155 166 0.015
negative regulation of intracellular transport GO:0032387 60 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
negative regulation of protein processing GO:0010955 142 0.015
stem cell division GO:0017145 2 0.015
regulation of dna metabolic process GO:0051052 153 0.015
single organism cell adhesion GO:0098602 179 0.015
positive regulation of neural precursor cell proliferation GO:2000179 2 0.015
ribose phosphate biosynthetic process GO:0046390 82 0.014
apoptotic signaling pathway GO:0097190 268 0.014
lipid transport GO:0006869 90 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
spermatid differentiation GO:0048515 4 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
embryonic eye morphogenesis GO:0048048 2 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
amide transport GO:0042886 76 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
regulation of cellular response to growth factor stimulus GO:0090287 76 0.014
defense response GO:0006952 315 0.014
maintenance of location GO:0051235 112 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
tissue migration GO:0090130 119 0.014
regulation of cellular component size GO:0032535 82 0.014

KCNH2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.046
inherited metabolic disorder DOID:655 242 0.046
central nervous system disease DOID:331 186 0.040
nervous system disease DOID:863 431 0.040
cardiovascular system disease DOID:1287 106 0.035
immune system disease DOID:2914 155 0.032
hematopoietic system disease DOID:74 100 0.032
musculoskeletal system disease DOID:17 223 0.030
sensory system disease DOID:0050155 203 0.023
muscular disease DOID:0080000 114 0.021
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
eye and adnexa disease DOID:1492 150 0.016
myopathy DOID:423 104 0.015
muscle tissue disease DOID:66 113 0.015
eye disease DOID:5614 149 0.014