Homo sapiens

9 known processes

PRNP

prion protein

(Aliases: GSS,PrPc,PrP33-35C,PrP27-30,MGC26679,prion,CJD,ASCR,CD230,PrP,PRIP)

PRNP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 6 0.697
cellular ketone metabolic process GO:0042180 80 0.678
regulation of kinase activity GO:0043549 314 0.659
protein ubiquitination GO:0016567 314 0.584
regulation of cellular ketone metabolic process GO:0010565 50 0.580
positive regulation of protein phosphorylation GO:0001934 313 0.563
regulation of cellular amine metabolic process GO:0033238 11 0.563
positive regulation of cellular amine metabolic process GO:0033240 7 0.558
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.552
cell cycle phase transition GO:0044770 173 0.476
amine metabolic process GO:0009308 44 0.448
cellular amine metabolic process GO:0044106 41 0.418
positive regulation of protein catabolic process GO:0045732 75 0.410
cell cycle g2 m phase transition GO:0044839 43 0.409
positive regulation of proteolysis GO:0045862 142 0.391
protein processing GO:0016485 226 0.345
g2 m transition of mitotic cell cycle GO:0000086 41 0.340
regulation of proteolysis GO:0030162 293 0.291
cellular response to dna damage stimulus GO:0006974 379 0.282
regulation of transferase activity GO:0051338 355 0.279
protein catabolic process GO:0030163 325 0.276
positive regulation of catabolic process GO:0009896 310 0.273
negative regulation of programmed cell death GO:0043069 321 0.270
Mouse
cell cycle g1 s phase transition GO:0044843 80 0.268
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.265
negative regulation of catalytic activity GO:0043086 335 0.254
protein maturation GO:0051604 233 0.253
regulation of proteasomal protein catabolic process GO:0061136 87 0.240
negative regulation of cell death GO:0060548 345 0.233
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.232
positive regulation of transferase activity GO:0051347 227 0.223
protein localization to organelle GO:0033365 280 0.221
positive regulation of transport GO:0051050 336 0.220
mitotic cell cycle phase transition GO:0044772 162 0.219
ubiquitin dependent protein catabolic process GO:0006511 206 0.211
endomembrane system organization GO:0010256 196 0.206
cellular macromolecule catabolic process GO:0044265 380 0.206
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.206
determination of adult lifespan GO:0008340 2 0.198
cellular amino acid metabolic process GO:0006520 116 0.197
system process GO:0003008 349 0.187
mitotic cell cycle GO:0000278 326 0.187
membrane organization GO:0061024 292 0.181
g2 dna damage checkpoint GO:0031572 26 0.180
positive regulation of phosphorylation GO:0042327 394 0.180
negative regulation of phosphorylation GO:0042326 174 0.179
Mouse
apoptotic signaling pathway GO:0097190 268 0.173
response to decreased oxygen levels GO:0036293 96 0.171
microtubule based process GO:0007017 210 0.167
regulation of establishment of protein localization GO:0070201 242 0.160
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.158
peptidyl tyrosine phosphorylation GO:0018108 170 0.156
regulation of cell cycle GO:0051726 393 0.156
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.156
response to abiotic stimulus GO:0009628 336 0.155
regulation of protein kinase activity GO:0045859 289 0.152
negative regulation of proteolysis GO:0045861 132 0.151
negative regulation of catabolic process GO:0009895 104 0.150
negative regulation of cellular component organization GO:0051129 235 0.149
positive regulation of cellular protein catabolic process GO:1903364 37 0.149
peptidyl tyrosine modification GO:0018212 170 0.149
protein modification by small protein conjugation GO:0032446 342 0.147
regulation of protein transport GO:0051223 213 0.145
post embryonic development GO:0009791 2 0.144
meiosis i GO:0007127 4 0.143
negative regulation of apoptotic process GO:0043066 316 0.143
Mouse
positive regulation of protein transport GO:0051222 135 0.142
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.141
regulation of cellular component biogenesis GO:0044087 281 0.137
spindle assembly GO:0051225 29 0.136
peptidyl serine phosphorylation GO:0018105 101 0.135
regulation of cell cycle process GO:0010564 266 0.135
regulation of protein stability GO:0031647 87 0.134
regulation of cell cycle phase transition GO:1901987 126 0.134
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.133
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.132
modification dependent protein catabolic process GO:0019941 209 0.129
mitotic cell cycle process GO:1903047 286 0.128
positive regulation of cell cycle process GO:0090068 106 0.124
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.120
negative regulation of protein maturation GO:1903318 142 0.118
positive regulation of cellular catabolic process GO:0031331 284 0.118
negative regulation of protein processing GO:0010955 142 0.116
proteasomal protein catabolic process GO:0010498 176 0.115
cellular protein catabolic process GO:0044257 261 0.113
nerve development GO:0021675 4 0.111
inorganic ion transmembrane transport GO:0098660 231 0.111
Mouse
organelle assembly GO:0070925 176 0.110
negative regulation of cell cycle GO:0045786 193 0.109
positive regulation of apoptotic process GO:0043065 246 0.109
regulation of protein processing GO:0070613 150 0.108
meiotic chromosome segregation GO:0045132 4 0.108
cell development GO:0048468 328 0.107
ion homeostasis GO:0050801 230 0.107
negative regulation of cell cycle phase transition GO:1901988 89 0.107
response to radiation GO:0009314 151 0.107
visual learning GO:0008542 1 0.106
regulation of mitotic cell cycle GO:0007346 189 0.105
posttranscriptional regulation of gene expression GO:0010608 213 0.104
negative regulation of protein phosphorylation GO:0001933 140 0.104
Mouse
negative regulation of blood pressure GO:0045776 3 0.103
negative regulation of systemic arterial blood pressure GO:0003085 1 0.102
cell cycle checkpoint GO:0000075 117 0.102
organelle inheritance GO:0048308 2 0.101
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.101
regulation of reactive oxygen species metabolic process GO:2000377 41 0.101
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.100
cellular chemical homeostasis GO:0055082 180 0.099
circulatory system development GO:0072359 262 0.098
negative regulation of organelle organization GO:0010639 126 0.097
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.097
multicellular organismal aging GO:0010259 3 0.096
regulation of microtubule cytoskeleton organization GO:0070507 61 0.096
regulation of protein maturation GO:1903317 150 0.096
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.095
negative regulation of protein modification process GO:0031400 200 0.095
Mouse
regulation of cell growth GO:0001558 135 0.094
reactive oxygen species metabolic process GO:0072593 75 0.093
positive regulation of intracellular protein transport GO:0090316 76 0.091
regulation of protein binding GO:0043393 66 0.090
cytokine production GO:0001816 247 0.089
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.089
Mouse
positive regulation of cellular component organization GO:0051130 376 0.088
negative regulation of phosphate metabolic process GO:0045936 267 0.087
Mouse
peptidyl threonine phosphorylation GO:0018107 41 0.085
peptidyl threonine modification GO:0018210 45 0.084
anatomical structure formation involved in morphogenesis GO:0048646 284 0.084
negative regulation of protein metabolic process GO:0051248 391 0.084
Mouse
regulation of cellular protein catabolic process GO:1903362 96 0.083
monocarboxylic acid metabolic process GO:0032787 185 0.082
regulation of protein localization GO:0032880 296 0.082
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.081
regulation of binding GO:0051098 111 0.081
negative regulation of mitotic cell cycle GO:0045930 102 0.080
response to hypoxia GO:0001666 96 0.080
transmembrane transport GO:0055085 399 0.079
Mouse
regulation of microtubule based process GO:0032886 74 0.079
visual behavior GO:0007632 2 0.078
cell projection organization GO:0030030 252 0.077
positive regulation of cytokine production GO:0001819 167 0.077
microtubule organizing center organization GO:0031023 62 0.076
response to reactive oxygen species GO:0000302 61 0.076
dna damage checkpoint GO:0000077 68 0.076
immune system development GO:0002520 195 0.074
nervous system development GO:0007399 293 0.074
negative regulation of cell cycle process GO:0010948 121 0.074
single organism membrane organization GO:0044802 268 0.071
metaphase anaphase transition of cell cycle GO:0044784 21 0.071
golgi organization GO:0007030 38 0.071
regulation of intracellular transport GO:0032386 195 0.070
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.070
growth GO:0040007 202 0.070
response to oxygen levels GO:0070482 100 0.068
regulation of protein serine threonine kinase activity GO:0071900 179 0.068
positive regulation of protein kinase activity GO:0045860 190 0.067
nucleoside triphosphate metabolic process GO:0009141 422 0.067
positive regulation of kinase activity GO:0033674 204 0.066
regulation of ligase activity GO:0051340 29 0.066
regulation of protein catabolic process GO:0042176 155 0.066
cell activation GO:0001775 213 0.065
Mouse
cellular component disassembly GO:0022411 92 0.065
negative regulation of phosphorus metabolic process GO:0010563 267 0.063
Mouse
protein localization to membrane GO:0072657 160 0.063
cardiovascular system development GO:0072358 262 0.061
response to external biotic stimulus GO:0043207 261 0.061
abducens nerve morphogenesis GO:0021598 1 0.061
mitotic cell cycle checkpoint GO:0007093 68 0.061
regulation of cell migration GO:0030334 289 0.061
cellular metal ion homeostasis GO:0006875 146 0.060
signal transduction by phosphorylation GO:0023014 297 0.058
cellular potassium ion transport GO:0071804 60 0.058
Mouse
cranial nerve development GO:0021545 4 0.057
nuclear division GO:0000280 128 0.057
cellular ion homeostasis GO:0006873 168 0.056
regulation of ubiquitin protein transferase activity GO:0051438 28 0.055
dna recombination GO:0006310 77 0.055
cellular macromolecular complex assembly GO:0034622 324 0.055
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.055
positive regulation of intracellular transport GO:0032388 104 0.054
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.054
regulation of organelle assembly GO:1902115 40 0.053
reciprocal meiotic recombination GO:0007131 4 0.053
cellular component morphogenesis GO:0032989 314 0.053
cell morphogenesis GO:0000902 296 0.052
nucleoside catabolic process GO:0009164 408 0.052
response to other organism GO:0051707 261 0.051
motor neuron axon guidance GO:0008045 2 0.051
regulation of protein complex assembly GO:0043254 147 0.050
memory GO:0007613 3 0.050
positive regulation of organelle organization GO:0010638 195 0.048
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.048
hindbrain development GO:0030902 3 0.048
peptidyl serine modification GO:0018209 106 0.047
regulation of peptidase activity GO:0052547 180 0.046
microtubule cytoskeleton organization GO:0000226 176 0.046
chromosome separation GO:0051304 23 0.045
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.044
enzyme linked receptor protein signaling pathway GO:0007167 303 0.044
positive regulation of protein ubiquitination GO:0031398 53 0.044
cation transmembrane transport GO:0098655 238 0.044
Mouse
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.044
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.043
lipid metabolic process GO:0006629 381 0.043
cell projection morphogenesis GO:0048858 129 0.043
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.042
response to wounding GO:0009611 168 0.042
negative regulation of apoptotic signaling pathway GO:2001234 97 0.042
cellular response to decreased oxygen levels GO:0036294 51 0.041
locomotory behavior GO:0007626 1 0.041
dna integrity checkpoint GO:0031570 71 0.041
golgi inheritance GO:0048313 2 0.041
axon cargo transport GO:0008088 2 0.041
positive regulation of mitosis GO:0045840 25 0.041
negative regulation of transferase activity GO:0051348 124 0.040
semicircular canal morphogenesis GO:0048752 1 0.040
adult locomotory behavior GO:0008344 1 0.040
negative regulation of cellular catabolic process GO:0031330 83 0.040
mitotic sister chromatid separation GO:0051306 18 0.040
extrinsic apoptotic signaling pathway GO:0097191 119 0.040
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.039
positive regulation of cell death GO:0010942 263 0.039
mitotic g1 s transition checkpoint GO:0044819 17 0.039
cell growth GO:0016049 160 0.039
neuromuscular junction development GO:0007528 3 0.038
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.038
Mouse
positive regulation of ligase activity GO:0051351 19 0.037
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.037
neuron differentiation GO:0030182 138 0.037
neurogenesis GO:0022008 169 0.037
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.036
blood vessel morphogenesis GO:0048514 162 0.036
regulation of synaptic plasticity GO:0048167 3 0.036
cytoskeleton dependent cytokinesis GO:0061640 22 0.035
cytoplasmic transport GO:0016482 379 0.035
negative regulation of hydrolase activity GO:0051346 182 0.035
rna processing GO:0006396 255 0.035
chemical homeostasis GO:0048878 306 0.035
ion transmembrane transport GO:0034220 338 0.035
Mouse
centrosome organization GO:0051297 58 0.034
negative regulation of protein kinase activity GO:0006469 98 0.034
regulation of mitosis GO:0007088 63 0.034
cellular response to hypoxia GO:0071456 51 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
immune response GO:0006955 307 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.034
embryonic neurocranium morphogenesis GO:0048702 1 0.034
regulation of apoptotic signaling pathway GO:2001233 175 0.034
negative regulation of cellular protein catabolic process GO:1903363 38 0.033
positive regulation of immune system process GO:0002684 283 0.033
Mouse
single organism cellular localization GO:1902580 332 0.033
hemopoiesis GO:0030097 180 0.033
regulation of cell motility GO:2000145 299 0.033
oogenesis GO:0048477 2 0.033
protein kinase b signaling GO:0043491 69 0.033
wnt signaling pathway GO:0016055 156 0.033
response to organic cyclic compound GO:0014070 204 0.032
regulation of intracellular protein transport GO:0033157 123 0.032
circulatory system process GO:0003013 113 0.031
regulation of response to external stimulus GO:0032101 222 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
reciprocal dna recombination GO:0035825 4 0.031
i kappab kinase nf kappab signaling GO:0007249 166 0.031
neural nucleus development GO:0048857 47 0.031
peripheral nervous system development GO:0007422 2 0.031
secretion by cell GO:0032940 226 0.030
sister chromatid segregation GO:0000819 54 0.030
regulation of cytokine production GO:0001817 232 0.030
Mouse
metencephalon development GO:0022037 2 0.030
chemotaxis GO:0006935 157 0.030
carbohydrate metabolic process GO:0005975 207 0.030
positive regulation of cell division GO:0051781 59 0.030
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.029
female gamete generation GO:0007292 2 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
secretion GO:0046903 254 0.029
cellular response to oxygen levels GO:0071453 55 0.029
positive regulation of secretion GO:0051047 116 0.028
purine containing compound biosynthetic process GO:0072522 88 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
response to growth factor GO:0070848 205 0.028
spindle organization GO:0007051 53 0.028
organic anion transport GO:0015711 103 0.028
blood vessel development GO:0001568 172 0.028
protein localization to plasma membrane GO:0072659 93 0.028
vasculature development GO:0001944 181 0.028
neurological system process GO:0050877 163 0.028
spindle checkpoint GO:0031577 26 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.027
centriole replication GO:0007099 13 0.027
positive regulation of developmental process GO:0051094 314 0.027
regulation of cytoplasmic transport GO:1903649 149 0.027
spindle assembly checkpoint GO:0071173 17 0.027
vesicle mediated transport GO:0016192 371 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
Mouse
regulation of response to dna damage stimulus GO:2001020 94 0.027
monovalent inorganic cation transport GO:0015672 128 0.027
Mouse
segmentation GO:0035282 4 0.026
negative regulation of sister chromatid segregation GO:0033046 17 0.026
single organismal cell cell adhesion GO:0016337 148 0.026
positive regulation of mapk cascade GO:0043410 190 0.026
intrinsic apoptotic signaling pathway GO:0097193 127 0.026
neurotransmitter secretion GO:0007269 4 0.026
positive regulation of chromosome organization GO:2001252 41 0.026
regulation of keratinocyte migration GO:0051547 4 0.026
reactive nitrogen species metabolic process GO:2001057 3 0.025
inner ear morphogenesis GO:0042472 4 0.025
myeloid leukocyte activation GO:0002274 34 0.025
purine containing compound catabolic process GO:0072523 411 0.025
cellular homeostasis GO:0019725 196 0.025
negative regulation of response to wounding GO:1903035 47 0.025
regulation of cellular response to stress GO:0080135 244 0.025
mitotic spindle assembly checkpoint GO:0007094 14 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
protein destabilization GO:0031648 12 0.025
regulation of cell division GO:0051302 116 0.025
regulation of membrane potential GO:0042391 95 0.025
intracellular protein transport GO:0006886 270 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
leukocyte activation GO:0045321 164 0.025
Mouse
response to oxidative stress GO:0006979 121 0.025
Mouse
cell division GO:0051301 168 0.024
central nervous system development GO:0007417 123 0.024
negative regulation of cell growth GO:0030308 83 0.024
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
establishment of protein localization to membrane GO:0090150 121 0.024
epithelium development GO:0060429 227 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
dna repair GO:0006281 198 0.023
positive regulation of cell migration GO:0030335 172 0.023
positive regulation of apoptotic signaling pathway GO:2001235 70 0.023
positive regulation of cell motility GO:2000147 177 0.023
endosomal transport GO:0016197 129 0.023
cytokinesis GO:0000910 96 0.023
response to light stimulus GO:0009416 87 0.023
regulation of centrosome cycle GO:0046605 15 0.023
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.023
embryo development GO:0009790 123 0.023
negative regulation of chromosome organization GO:2001251 48 0.023
protein targeting GO:0006605 187 0.023
negative regulation of growth GO:0045926 97 0.023
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
negative regulation of protein catabolic process GO:0042177 59 0.023
potassium ion transport GO:0006813 62 0.023
Mouse
regulation of systemic arterial blood pressure GO:0003073 19 0.023
protein localization to chromatin GO:0071168 11 0.023
heart development GO:0007507 95 0.022
regulation of dna metabolic process GO:0051052 153 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
sensory organ development GO:0007423 52 0.022
mitotic sister chromatid segregation GO:0000070 53 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.022
organophosphate catabolic process GO:0046434 430 0.022
positive regulation of keratinocyte migration GO:0051549 4 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.022
regulation of wnt signaling pathway GO:0030111 123 0.021
regulation of mapk cascade GO:0043408 262 0.021
lymphocyte activation GO:0046649 133 0.021
Mouse
cilium morphogenesis GO:0060271 75 0.021
dermatan sulfate proteoglycan biosynthetic process GO:0050651 4 0.021
cellular response to glucocorticoid stimulus GO:0071385 4 0.021
mitotic nuclear division GO:0007067 119 0.021
regulation of leukocyte activation GO:0002694 115 0.021
Mouse
purine nucleoside catabolic process GO:0006152 398 0.021
protein localization to chromosome GO:0034502 30 0.020
cellular cation homeostasis GO:0030003 163 0.020
cranial nerve morphogenesis GO:0021602 1 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
mating GO:0007618 1 0.020
response to steroid hormone GO:0048545 80 0.020
negative regulation of kinase activity GO:0033673 106 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
cellular amide metabolic process GO:0043603 69 0.020
regulation of nuclear division GO:0051783 65 0.019
skeletal system development GO:0001501 79 0.019
regulation of centrosome duplication GO:0010824 14 0.019
cellular response to starvation GO:0009267 58 0.019
maintenance of location GO:0051235 112 0.019
cranial nerve formation GO:0021603 1 0.019
regulation of protein secretion GO:0050708 86 0.019
regulation of cell development GO:0060284 161 0.019
negative regulation of cytokine production GO:0001818 82 0.019
Mouse
plasma membrane organization GO:0007009 115 0.019
cochlea development GO:0090102 1 0.019
chromosome segregation GO:0007059 114 0.019
regulation of homeostatic process GO:0032844 121 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
epithelial cell differentiation GO:0030855 141 0.019
brain development GO:0007420 97 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
regulation of transporter activity GO:0032409 82 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
semicircular canal formation GO:0060876 1 0.018
macrophage fusion GO:0034238 1 0.018
molting cycle GO:0042303 28 0.018
gtp metabolic process GO:0046039 239 0.018
regulation of chromosome segregation GO:0051983 44 0.017
centrosome duplication GO:0051298 28 0.017
positive regulation of secretion by cell GO:1903532 108 0.017
regulation of peptidyl threonine phosphorylation GO:0010799 15 0.017
centrosome cycle GO:0007098 32 0.017
response to fungus GO:0009620 4 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
protein stabilization GO:0050821 64 0.017
regulation of transmembrane transporter activity GO:0022898 74 0.017
regulation of lymphocyte activation GO:0051249 103 0.017
Mouse
sensory perception GO:0007600 103 0.017
peptide metabolic process GO:0006518 51 0.017
mrna metabolic process GO:0016071 175 0.017
angiogenesis GO:0001525 147 0.017
response to biotic stimulus GO:0009607 276 0.017
cyclic nucleotide biosynthetic process GO:0009190 61 0.016
neural crest cell migration GO:0001755 2 0.016
regulation of cytokinesis GO:0032465 45 0.016
regulation of mitotic sister chromatid separation GO:0010965 27 0.016
protein import GO:0017038 130 0.016
response to virus GO:0009615 126 0.016
neuron remodeling GO:0016322 2 0.016
cell part morphogenesis GO:0032990 137 0.016
metal ion homeostasis GO:0055065 169 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.016
cell adhesion GO:0007155 325 0.016
regulation of mitotic sister chromatid segregation GO:0033047 27 0.016
regulation of growth GO:0040008 165 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
blood circulation GO:0008015 113 0.015
mitotic spindle checkpoint GO:0071174 18 0.015
negative regulation of mitosis GO:0045839 24 0.015
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.015
associative learning GO:0008306 1 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
reproduction GO:0000003 63 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
ameboidal type cell migration GO:0001667 135 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
transition metal ion homeostasis GO:0055076 31 0.015
alcohol metabolic process GO:0006066 114 0.015
neuronal action potential GO:0019228 9 0.015
resolution of meiotic recombination intermediates GO:0000712 3 0.015
cognition GO:0050890 43 0.015
generation of neurons GO:0048699 152 0.015
positive regulation of mitotic cell cycle GO:0045931 60 0.015
regulation of chromosome organization GO:0033044 103 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.015
generation of precursor metabolites and energy GO:0006091 68 0.015
positive regulation of immune response GO:0050778 159 0.015
Mouse
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.015
calcium ion homeostasis GO:0055074 122 0.015
response to lipid GO:0033993 206 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
cation homeostasis GO:0055080 189 0.014
regulation of cell activation GO:0050865 125 0.014
Mouse
innate immune response GO:0045087 178 0.014
regulation of dna repair GO:0006282 47 0.014
convergent extension GO:0060026 1 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
negative regulation of chromosome segregation GO:0051985 18 0.014
cellular lipid metabolic process GO:0044255 303 0.014
positive regulation of epithelial cell migration GO:0010634 55 0.014
mitotic spindle organization GO:0007052 27 0.014
response to organonitrogen compound GO:0010243 156 0.014
small molecule biosynthetic process GO:0044283 157 0.014
morphogenesis of an epithelium GO:0002009 60 0.014
organ formation GO:0048645 3 0.014
tissue morphogenesis GO:0048729 96 0.014
activation of protein kinase activity GO:0032147 90 0.014
meiotic chromosome separation GO:0051307 3 0.014

PRNP disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.135
myopathy DOID:423 104 0.118
muscular disease DOID:0080000 114 0.118
muscle tissue disease DOID:66 113 0.118
muscular dystrophy DOID:9884 51 0.066
emery dreifuss muscular dystrophy DOID:11726 6 0.066
central nervous system disease DOID:331 186 0.060
nervous system disease DOID:863 431 0.060
disease of metabolism DOID:0014667 295 0.054
joubert syndrome DOID:0050777 18 0.040
sensory system disease DOID:0050155 203 0.039
eye and adnexa disease DOID:1492 150 0.025
acquired metabolic disease DOID:0060158 58 0.023
neurodegenerative disease DOID:1289 102 0.022
disease of mental health DOID:150 70 0.020
eye disease DOID:5614 149 0.019
retinal disease DOID:5679 118 0.017
retinal degeneration DOID:8466 89 0.017
connective tissue disease DOID:65 109 0.016