Homo sapiens

44 known processes

BIN2

bridging integrator 2

(Aliases: BRAP-1)

BIN2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lymphocyte activation GO:0046649 133 0.332
positive regulation of nucleotide metabolic process GO:0045981 230 0.307
small gtpase mediated signal transduction GO:0007264 78 0.295
purine nucleoside catabolic process GO:0006152 398 0.284
immune response GO:0006955 307 0.239
regulation of purine nucleotide metabolic process GO:1900542 264 0.224
leukocyte activation GO:0045321 164 0.223
regulation of immune response GO:0050776 201 0.221
regulation of cellular component movement GO:0051270 334 0.220
regulation of gtp catabolic process GO:0033124 180 0.219
cytokine production GO:0001816 247 0.219
regulation of nucleotide catabolic process GO:0030811 205 0.212
positive regulation of immune system process GO:0002684 283 0.212
purine ribonucleoside catabolic process GO:0046130 398 0.211
ras protein signal transduction GO:0007265 73 0.202
positive regulation of hydrolase activity GO:0051345 331 0.200
ribonucleoside catabolic process GO:0042454 406 0.187
nucleoside phosphate catabolic process GO:1901292 412 0.186
innate immune response GO:0045087 178 0.184
cell chemotaxis GO:0060326 112 0.181
cell activation GO:0001775 213 0.177
ribonucleoside triphosphate metabolic process GO:0009199 412 0.174
nucleotide catabolic process GO:0009166 408 0.170
response to external biotic stimulus GO:0043207 261 0.167
secretion by cell GO:0032940 226 0.165
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.162
positive regulation of immune response GO:0050778 159 0.158
response to oxygen containing compound GO:1901700 369 0.157
purine nucleoside triphosphate catabolic process GO:0009146 392 0.152
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.150
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.148
positive regulation of nucleotide catabolic process GO:0030813 185 0.148
nucleoside triphosphate catabolic process GO:0009143 394 0.147
guanosine containing compound catabolic process GO:1901069 239 0.147
ribonucleotide catabolic process GO:0009261 405 0.146
gtp catabolic process GO:0006184 237 0.143
nucleoside catabolic process GO:0009164 408 0.137
t cell activation GO:0042110 99 0.135
regulation of nucleoside metabolic process GO:0009118 209 0.134
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.133
cation transport GO:0006812 331 0.132
mapk cascade GO:0000165 288 0.132
signal transduction by phosphorylation GO:0023014 297 0.130
regulation of mapk cascade GO:0043408 262 0.129
vesicle mediated transport GO:0016192 371 0.128
regulation of cell migration GO:0030334 289 0.127
positive regulation of mapk cascade GO:0043410 190 0.127
purine ribonucleotide catabolic process GO:0009154 404 0.126
negative regulation of cell death GO:0060548 345 0.126
ribonucleoside triphosphate catabolic process GO:0009203 391 0.125
positive regulation of gtpase activity GO:0043547 166 0.125
purine nucleoside triphosphate metabolic process GO:0009144 412 0.124
regulation of nucleotide metabolic process GO:0006140 269 0.123
positive regulation of gtp catabolic process GO:0033126 166 0.122
purine nucleotide catabolic process GO:0006195 405 0.122
nucleoside triphosphate metabolic process GO:0009141 422 0.119
positive regulation of ras gtpase activity GO:0032320 117 0.117
positive regulation of transport GO:0051050 336 0.114
guanosine containing compound metabolic process GO:1901068 244 0.114
positive regulation of nucleoside metabolic process GO:0045979 186 0.112
cellular amine metabolic process GO:0044106 41 0.111
lymphocyte proliferation GO:0046651 70 0.110
purinergic nucleotide receptor signaling pathway GO:0035590 4 0.110
leukocyte migration GO:0050900 107 0.110
response to other organism GO:0051707 261 0.107
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.105
rho protein signal transduction GO:0007266 26 0.105
regulation of secretion by cell GO:1903530 177 0.105
organophosphate catabolic process GO:0046434 430 0.104
response to lipid GO:0033993 206 0.104
granulocyte migration GO:0097530 40 0.104
gtp metabolic process GO:0046039 239 0.099
positive regulation of cell death GO:0010942 263 0.098
Human
regulation of gtpase activity GO:0043087 180 0.097
response to biotic stimulus GO:0009607 276 0.096
purine ribonucleoside metabolic process GO:0046128 437 0.096
regulation of cell activation GO:0050865 125 0.095
positive regulation of cellular catabolic process GO:0031331 284 0.093
system process GO:0003008 349 0.093
regulation of cytokine production GO:0001817 232 0.093
immune system development GO:0002520 195 0.091
negative regulation of cell proliferation GO:0008285 228 0.091
regulation of locomotion GO:0040012 329 0.089
positive regulation of phosphorylation GO:0042327 394 0.089
defense response GO:0006952 315 0.087
cellular response to oxygen containing compound GO:1901701 276 0.086
chemotaxis GO:0006935 157 0.080
leukocyte proliferation GO:0070661 74 0.080
regulation of immune effector process GO:0002697 91 0.080
regulation of leukocyte migration GO:0002685 63 0.077
myeloid cell differentiation GO:0030099 117 0.077
positive regulation of locomotion GO:0040017 186 0.076
regulation of small gtpase mediated signal transduction GO:0051056 156 0.076
positive regulation of cell activation GO:0050867 81 0.076
regulation of lymphocyte activation GO:0051249 103 0.075
purine containing compound catabolic process GO:0072523 411 0.074
cellular amino acid metabolic process GO:0006520 116 0.073
metal ion transport GO:0030001 272 0.072
positive regulation of apoptotic process GO:0043065 246 0.072
Human
positive regulation of catabolic process GO:0009896 310 0.071
glycosyl compound catabolic process GO:1901658 413 0.070
regulation of rho gtpase activity GO:0032319 66 0.070
regulation of anatomical structure morphogenesis GO:0022603 286 0.070
regulation of eosinophil activation GO:1902566 2 0.069
regulation of leukocyte proliferation GO:0070663 67 0.069
post embryonic development GO:0009791 2 0.069
amine metabolic process GO:0009308 44 0.068
positive regulation of cellular component organization GO:0051130 376 0.068
regulation of ras gtpase activity GO:0032318 128 0.068
negative regulation of programmed cell death GO:0043069 321 0.067
hematopoietic or lymphoid organ development GO:0048534 186 0.064
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.063
cellular response to molecule of bacterial origin GO:0071219 62 0.063
divalent metal ion transport GO:0070838 152 0.063
biological adhesion GO:0022610 331 0.062
response to cytokine GO:0034097 232 0.062
cellular ion homeostasis GO:0006873 168 0.062
cellular response to biotic stimulus GO:0071216 71 0.062
erk1 and erk2 cascade GO:0070371 104 0.061
regulation of rho protein signal transduction GO:0035023 79 0.061
positive regulation of programmed cell death GO:0043068 249 0.061
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.061
regulation of cell motility GO:2000145 299 0.060
negative regulation of multicellular organismal process GO:0051241 317 0.059
regulation of leukocyte activation GO:0002694 115 0.058
positive regulation of cell proliferation GO:0008284 301 0.058
regulation of defense response GO:0031347 154 0.058
inflammatory response GO:0006954 79 0.058
actin filament based process GO:0030029 224 0.057
regulation of vesicle mediated transport GO:0060627 130 0.057
negative regulation of cellular component organization GO:0051129 235 0.056
activation of innate immune response GO:0002218 55 0.056
hemopoiesis GO:0030097 180 0.056
regulation of secretion GO:0051046 194 0.056
negative regulation of immune system process GO:0002683 136 0.056
activation of immune response GO:0002253 114 0.056
positive regulation of leukocyte proliferation GO:0070665 48 0.055
negative regulation of apoptotic process GO:0043066 316 0.055
divalent inorganic cation transport GO:0072511 158 0.055
regulation of ion transport GO:0043269 189 0.054
immune effector process GO:0002252 159 0.054
positive regulation of cellular amine metabolic process GO:0033240 7 0.054
second messenger mediated signaling GO:0019932 78 0.054
blood vessel development GO:0001568 172 0.053
cation homeostasis GO:0055080 189 0.053
positive regulation of response to external stimulus GO:0032103 88 0.053
positive regulation of developmental process GO:0051094 314 0.053
Human
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.052
cellular ketone metabolic process GO:0042180 80 0.052
taxis GO:0042330 157 0.052
regulation of calcium ion transport GO:0051924 79 0.051
cell adhesion GO:0007155 325 0.051
positive regulation of astrocyte chemotaxis GO:2000464 1 0.050
regulation of purine nucleotide catabolic process GO:0033121 205 0.050
regulation of lymphocyte proliferation GO:0050670 64 0.049
positive regulation of cytokine production GO:0001819 167 0.049
secretion GO:0046903 254 0.048
positive regulation of behavior GO:0048520 60 0.045
leukocyte mediated immunity GO:0002443 59 0.045
type i interferon secretion GO:0072641 1 0.045
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.045
regulation of response to external stimulus GO:0032101 222 0.045
positive regulation of cell differentiation GO:0045597 211 0.045
Human
regulation of cytokine secretion GO:0050707 57 0.044
mononuclear cell proliferation GO:0032943 71 0.044
regulation of intracellular transport GO:0032386 195 0.044
calcium ion transport GO:0006816 147 0.044
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.044
positive regulation of lymphocyte activation GO:0051251 73 0.044
regulation of ras protein signal transduction GO:0046578 155 0.043
response to virus GO:0009615 126 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
negative regulation of catalytic activity GO:0043086 335 0.042
interleukin 12 secretion GO:0072610 1 0.042
apoptotic signaling pathway GO:0097190 268 0.042
regulation of leukocyte mediated immunity GO:0002703 38 0.042
myeloid leukocyte migration GO:0097529 62 0.041
regulation of multi organism process GO:0043900 157 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.041
cellular macromolecular complex assembly GO:0034622 324 0.041
Human
cellular response to lipopolysaccharide GO:0071222 57 0.040
regulation of cellular component biogenesis GO:0044087 281 0.040
regulation of t cell activation GO:0050863 77 0.040
positive regulation of lymphocyte proliferation GO:0050671 46 0.040
astrocyte chemotaxis GO:0035700 1 0.040
response to abiotic stimulus GO:0009628 336 0.040
regulation of protein localization GO:0032880 296 0.039
regulation of myeloid leukocyte differentiation GO:0002761 39 0.039
regulation of cell cycle GO:0051726 393 0.039
Human
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.038
response to molecule of bacterial origin GO:0002237 82 0.038
regulation of metal ion transport GO:0010959 120 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.037
actin cytoskeleton organization GO:0030036 207 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
blood vessel morphogenesis GO:0048514 162 0.037
endocytosis GO:0006897 159 0.037
positive regulation of rho gtpase activity GO:0032321 56 0.036
immune response regulating signaling pathway GO:0002764 97 0.036
chemokine c c motif ligand 11 production GO:0071954 1 0.036
response to organic cyclic compound GO:0014070 204 0.036
positive regulation of t cell activation GO:0050870 54 0.036
positive regulation of cell motility GO:2000147 177 0.036
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.035
cytoplasmic transport GO:0016482 379 0.035
positive regulation of mononuclear cell proliferation GO:0032946 47 0.035
immune response activating signal transduction GO:0002757 90 0.035
positive regulation of cell migration GO:0030335 172 0.034
positive regulation of cellular component movement GO:0051272 181 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
positive regulation of leukocyte differentiation GO:1902107 37 0.034
dephosphorylation GO:0016311 209 0.034
negative regulation of cd8 positive alpha beta t cell activation GO:2001186 1 0.034
exocytosis GO:0006887 71 0.034
leukocyte chemotaxis GO:0030595 76 0.033
cell projection organization GO:0030030 252 0.033
multicellular organismal aging GO:0010259 3 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
g protein coupled receptor signaling pathway GO:0007186 207 0.033
protein secretion GO:0009306 98 0.033
determination of adult lifespan GO:0008340 2 0.033
regulation of erk1 and erk2 cascade GO:0070372 99 0.033
calcium mediated signaling GO:0019722 44 0.032
positive regulation of transferase activity GO:0051347 227 0.032
sensory perception of pain GO:0019233 4 0.032
regulation of protein secretion GO:0050708 86 0.032
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
osteoclast development GO:0036035 2 0.031
cellular protein complex assembly GO:0043623 188 0.031
single organism cell adhesion GO:0098602 179 0.030
reactive nitrogen species metabolic process GO:2001057 3 0.030
positive regulation of leukocyte activation GO:0002696 80 0.030
response to lipopolysaccharide GO:0032496 70 0.030
nitrogen compound transport GO:0071705 191 0.030
single organismal cell cell adhesion GO:0016337 148 0.030
cellular component morphogenesis GO:0032989 314 0.030
positive regulation of leukocyte chemotaxis GO:0002690 38 0.030
membrane organization GO:0061024 292 0.030
myeloid dendritic cell chemotaxis GO:0002408 3 0.030
immune response in mucosal associated lymphoid tissue GO:0002386 1 0.029
cellular chemical homeostasis GO:0055082 180 0.029
cellular response to cytokine stimulus GO:0071345 181 0.029
metal ion homeostasis GO:0055065 169 0.029
interleukin 8 mediated signaling pathway GO:0038112 2 0.029
cellular cation homeostasis GO:0030003 163 0.029
regulation of cell morphogenesis GO:0022604 153 0.029
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.028
regulation of angiogenesis GO:0045765 92 0.028
sequestering of metal ion GO:0051238 24 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.028
regulation of innate immune response GO:0045088 97 0.028
sequestering of calcium ion GO:0051208 17 0.027
response to hyperoxia GO:0055093 4 0.027
oogenesis GO:0048477 2 0.027
female gamete generation GO:0007292 2 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.027
maintenance of location GO:0051235 112 0.027
negative regulation of cellular component movement GO:0051271 106 0.027
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.027
cell development GO:0048468 328 0.027
Human
cell activation involved in immune response GO:0002263 30 0.027
protein polymerization GO:0051258 71 0.027
neuromuscular junction development GO:0007528 3 0.027
vasculature development GO:0001944 181 0.027
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.027
cellular response to lipid GO:0071396 127 0.027
positive regulation of innate immune response GO:0045089 79 0.027
peptidyl tyrosine modification GO:0018212 170 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.026
oxidation reduction process GO:0055114 396 0.026
neutrophil migration GO:1990266 25 0.026
negative regulation of developmental process GO:0051093 247 0.026
cell morphogenesis GO:0000902 296 0.026
angiogenesis GO:0001525 147 0.026
negative regulation of cell activation GO:0050866 33 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.025
negative regulation of transport GO:0051051 176 0.025
eosinophil activation involved in immune response GO:0002278 2 0.025
cytokine biosynthetic process GO:0042089 37 0.025
serotonin secretion GO:0001820 1 0.025
cell type specific apoptotic process GO:0097285 125 0.025
positive regulation of rac gtpase activity GO:0032855 31 0.025
protein catabolic process GO:0030163 325 0.025
cellular response to radiation GO:0071478 65 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
negative regulation of defense response GO:0031348 47 0.024
regulation of protein serine threonine kinase activity GO:0071900 179 0.024
regulation of vasculature development GO:1901342 97 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
cellular response to abiotic stimulus GO:0071214 117 0.024
negative regulation of regulated secretory pathway GO:1903306 1 0.024
cellular homeostasis GO:0019725 196 0.024
positive regulation of kinase activity GO:0033674 204 0.024
reactive oxygen species biosynthetic process GO:1903409 4 0.024
myeloid leukocyte differentiation GO:0002573 60 0.024
protein oligomerization GO:0051259 173 0.023
negative regulation of eosinophil activation GO:1902567 1 0.023
regulation of cell cycle process GO:0010564 266 0.023
Human
regulation of t cell proliferation GO:0042129 42 0.023
actin polymerization or depolymerization GO:0008154 56 0.023
cell projection assembly GO:0030031 126 0.023
positive regulation of cell cycle process GO:0090068 106 0.023
regulation of transforming growth factor beta secretion GO:2001201 1 0.022
regulation of gamma delta t cell activation GO:0046643 1 0.022
negative regulation of locomotion GO:0040013 118 0.022
regulation of leukocyte chemotaxis GO:0002688 46 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
regulation of tumor necrosis factor production GO:0032680 43 0.022
post embryonic organ development GO:0048569 1 0.022
cellular lipid metabolic process GO:0044255 303 0.022
regulation of peptidase activity GO:0052547 180 0.022
cellular protein catabolic process GO:0044257 261 0.022
regulation of proteolysis GO:0030162 293 0.022
regulation of protein kinase activity GO:0045859 289 0.022
detection of stimulus GO:0051606 85 0.022
positive regulation of ion transport GO:0043270 87 0.022
serotonin transport GO:0006837 3 0.022
single organism cellular localization GO:1902580 332 0.021
regulation of ion homeostasis GO:2000021 73 0.021
eosinophil activation GO:0043307 3 0.021
positive regulation of protein transport GO:0051222 135 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
lipid metabolic process GO:0006629 381 0.021
regulation of homeostatic process GO:0032844 121 0.021
positive regulation of calcium ion transport GO:0051928 51 0.021
neurological system process GO:0050877 163 0.021
regulation of protein transport GO:0051223 213 0.021
response to bacterium GO:0009617 144 0.021
central nervous system development GO:0007417 123 0.021
Human
circulatory system development GO:0072359 262 0.021
interferon beta production GO:0032608 23 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
calcium ion homeostasis GO:0055074 122 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
positive regulation of defense response GO:0031349 87 0.020
extrinsic apoptotic signaling pathway GO:0097191 119 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.020
regulation of myeloid cell differentiation GO:0045637 81 0.020
response to wounding GO:0009611 168 0.020
regulation of kinase activity GO:0043549 314 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
lymphocyte mediated immunity GO:0002449 48 0.019
negative regulation of cell cycle GO:0045786 193 0.019
Human
regulation of cell differentiation GO:0045595 393 0.019
Human
response to decreased oxygen levels GO:0036293 96 0.019
positive regulation of immune effector process GO:0002699 40 0.019
ion homeostasis GO:0050801 230 0.019
negative regulation of alpha beta t cell activation GO:0046636 3 0.019
negative regulation of cytokine production GO:0001818 82 0.019
t cell proliferation GO:0042098 45 0.019
behavior GO:0007610 112 0.019
response to organonitrogen compound GO:0010243 156 0.019
natural killer cell mediated immunity GO:0002228 23 0.019
regulation of behavior GO:0050795 82 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
regulation of transferase activity GO:0051338 355 0.018
regulation of cellular response to stress GO:0080135 244 0.018
regulation of actin filament based process GO:0032970 141 0.018
cellular calcium ion homeostasis GO:0006874 117 0.018
nervous system development GO:0007399 293 0.018
Human
regulation of protein processing GO:0070613 150 0.018
chemical homeostasis GO:0048878 306 0.018
transforming growth factor beta secretion GO:0038044 1 0.018
positive regulation of secretion GO:0051047 116 0.018
cellular response to external stimulus GO:0071496 111 0.018
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.018
sensory perception GO:0007600 103 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.018
positive regulation of regulatory t cell differentiation GO:0045591 3 0.018
lymphocyte differentiation GO:0030098 35 0.018
negative regulation of interleukin 12 secretion GO:2001183 1 0.018
receptor metabolic process GO:0043112 81 0.017
actin filament polymerization GO:0030041 45 0.017
camp metabolic process GO:0046058 61 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
mitotic cell cycle GO:0000278 326 0.017
positive regulation of secretion by cell GO:1903532 108 0.017
negative regulation of cell migration GO:0030336 102 0.017
regulation of chemotaxis GO:0050920 74 0.017
type i interferon production GO:0032606 27 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
cellular response to ammonium ion GO:0071242 4 0.017
regulation of interferon gamma production GO:0032649 36 0.017
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.017
regulation of binding GO:0051098 111 0.017
regulation of system process GO:0044057 101 0.017
positive regulation of proteolysis GO:0045862 142 0.017
negative regulation of osteoclast development GO:2001205 1 0.017
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
regulation of regulatory t cell differentiation GO:0045589 4 0.016
interferon beta secretion GO:0035546 1 0.016
positive regulation of organelle organization GO:0010638 195 0.016
protein maturation GO:0051604 233 0.016
actin filament organization GO:0007015 128 0.016
endomembrane system organization GO:0010256 196 0.016
negative regulation of secretion by cell GO:1903531 52 0.016
regulation of dendritic cell apoptotic process GO:2000668 4 0.016
cell division GO:0051301 168 0.016
negative regulation of cell motility GO:2000146 104 0.016
cellular response to diacyl bacterial lipopeptide GO:0071726 2 0.016
positive regulation of leukocyte migration GO:0002687 46 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
regulation of cell development GO:0060284 161 0.016
Human
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.016
leukocyte apoptotic process GO:0071887 31 0.016
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.016
regulation of endocytosis GO:0030100 72 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of leukocyte differentiation GO:1902105 61 0.016
negative regulation of t cell mediated cytotoxicity GO:0001915 1 0.016
regulation of b cell proliferation GO:0030888 18 0.016
response to axon injury GO:0048678 1 0.016
defense response to other organism GO:0098542 129 0.016
ossification GO:0001503 121 0.016
protein processing GO:0016485 226 0.015
regulation of response to biotic stimulus GO:0002831 55 0.015
regulation of protein maturation GO:1903317 150 0.015
positive regulation of cell cycle GO:0045787 140 0.015
leukocyte differentiation GO:0002521 98 0.015
response to oxygen levels GO:0070482 100 0.015
growth GO:0040007 202 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
sulfur compound metabolic process GO:0006790 101 0.015
regulation of astrocyte chemotaxis GO:2000458 1 0.015
positive regulation of acute inflammatory response GO:0002675 2 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
cd8 positive alpha beta t cell activation GO:0036037 3 0.015
response to nitrogen compound GO:1901698 184 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
microtubule based process GO:0007017 210 0.015
negative regulation of homeostatic process GO:0032845 59 0.015
osteoclast differentiation GO:0030316 21 0.015
stress activated protein kinase signaling cascade GO:0031098 94 0.015
single organism membrane organization GO:0044802 268 0.015
granulocyte chemotaxis GO:0071621 37 0.015
interleukin 1 beta production GO:0032611 22 0.014
heterotypic cell cell adhesion GO:0034113 28 0.014
regulation of anatomical structure size GO:0090066 101 0.014
mitotic cell cycle process GO:1903047 286 0.014
protein ubiquitination GO:0016567 314 0.014
tissue migration GO:0090130 119 0.014
interferon gamma production GO:0032609 39 0.014
protein localization to organelle GO:0033365 280 0.014
tumor necrosis factor production GO:0032640 43 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
glycerolipid metabolic process GO:0046486 107 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
negative regulation of leukocyte mediated immunity GO:0002704 14 0.014
ameboidal type cell migration GO:0001667 135 0.014
antigen receptor mediated signaling pathway GO:0050851 38 0.014
endothelial cell migration GO:0043542 86 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
regulation of lymphocyte mediated immunity GO:0002706 33 0.014
muscle system process GO:0003012 81 0.013
pattern recognition receptor signaling pathway GO:0002221 48 0.013
regulation of sequestering of calcium ion GO:0051282 41 0.013
striated muscle contraction GO:0006941 52 0.013
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.013
spermatid differentiation GO:0048515 4 0.013
receptor mediated endocytosis GO:0006898 84 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
regulation of stress activated mapk cascade GO:0032872 84 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
locomotory behavior GO:0007626 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
response to hypoxia GO:0001666 96 0.013
cation transmembrane transport GO:0098655 238 0.013
response to hormone GO:0009725 175 0.013
segmentation GO:0035282 4 0.013
phosphatidylinositol mediated signaling GO:0048015 55 0.013
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.013
regulation of interleukin 10 secretion GO:2001179 4 0.013
rac protein signal transduction GO:0016601 12 0.013
cell cycle phase transition GO:0044770 173 0.013
monocyte chemotaxis GO:0002548 20 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
regulation of protein complex assembly GO:0043254 147 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
oocyte development GO:0048599 1 0.013

BIN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.018
Human
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014