|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
1.000
|
Human |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
1.000
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.998
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.998
|
Human |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.991
|
Human |
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.988
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.982
|
Human |
|
|
hippo signaling
|
GO:0035329 |
20 |
0.973
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.963
|
Human Mouse |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.946
|
Human |
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.927
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.927
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.911
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.895
|
Human Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.888
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.873
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.871
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.869
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.854
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.838
|
Human Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.834
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.830
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.829
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.817
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.796
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.777
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.743
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.741
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.733
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.726
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.725
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.712
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.710
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.704
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.686
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.684
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.665
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.657
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.616
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.610
|
|
|
|
embryonic retina morphogenesis in camera type eye
|
GO:0060059 |
1 |
0.610
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.595
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.582
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.581
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.569
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.558
|
|
|
|
growth
|
GO:0040007 |
202 |
0.552
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.545
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.539
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.528
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.524
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.523
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.516
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.515
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.514
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.512
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.511
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.508
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.506
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.504
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.499
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.497
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.495
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.490
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.486
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.485
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.480
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.479
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.479
|
Human Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.475
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.475
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.469
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.467
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.457
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.444
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.443
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.443
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.440
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.438
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.430
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.420
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.420
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.413
|
Human Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.402
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.402
|
|
|
|
negative regulation of ras gtpase activity
|
GO:0034261 |
6 |
0.395
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.392
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.390
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.385
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.375
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.370
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.370
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.368
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.364
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.363
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.356
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.350
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.345
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.340
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.338
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.335
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.333
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.320
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.315
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.296
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.295
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.291
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.286
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.281
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
12 |
0.279
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.276
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.270
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.268
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.263
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.263
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.261
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.258
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.256
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.255
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.246
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.241
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.240
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.237
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.236
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.235
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.234
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.231
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.230
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.229
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.229
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.226
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.224
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.223
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.221
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.220
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.216
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.214
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.213
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.213
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.211
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.210
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.205
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.204
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.202
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.200
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.199
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.195
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.195
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.188
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.188
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.181
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.181
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.181
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.180
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.176
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.176
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.175
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.172
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.171
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.170
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.168
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.167
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.165
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.164
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.164
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.160
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.160
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.160
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.155
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.150
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.148
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.147
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.147
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.146
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.146
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.143
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.143
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.141
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.139
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.139
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.138
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.137
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.135
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.135
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.134
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.134
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.134
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.133
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.132
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.130
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.127
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.126
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.125
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.123
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.123
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.120
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.120
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.120
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.119
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.118
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.117
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.117
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.117
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.115
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.111
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.110
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.107
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.107
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.106
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.106
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.105
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.103
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.102
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.101
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.098
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.097
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.096
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.096
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.094
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.094
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.094
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.094
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.094
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.093
|
|
|
|
mrna transcription
|
GO:0009299 |
8 |
0.089
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.088
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.088
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.088
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.086
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.085
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.084
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.084
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.083
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.082
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.080
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.080
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.080
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.080
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.079
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.079
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.078
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.077
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
6 |
0.077
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.076
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.074
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.074
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.074
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.073
|
|
|
|
aging
|
GO:0007568 |
66 |
0.072
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.072
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.071
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.070
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.070
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.069
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.068
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.067
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.067
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.067
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.066
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.065
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.065
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.065
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.065
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.065
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.065
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.064
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.064
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.064
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.064
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.063
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.063
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.063
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.063
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.062
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.062
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.061
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.061
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.061
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.060
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.060
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.060
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.059
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.059
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.058
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.057
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.057
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.057
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.057
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.057
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.056
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.056
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.055
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.055
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.055
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.055
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.054
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.054
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.054
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.053
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.053
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.053
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.052
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.052
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.052
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.051
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.051
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.050
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.050
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.050
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.050
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.050
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.049
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.048
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.048
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.048
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.047
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.047
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.047
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.045
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.045
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.045
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.045
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.044
|
|
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.044
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.044
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.044
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.044
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.043
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.043
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.043
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.043
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.043
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.043
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.042
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.042
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.041
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.041
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.041
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.041
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.041
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.041
|
|
|
|
regulation of rap gtpase activity
|
GO:0032317 |
8 |
0.040
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.040
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.040
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.040
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.040
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.039
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.039
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.039
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.038
|
|
|
|
memory
|
GO:0007613 |
3 |
0.038
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.038
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.038
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.038
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.037
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.037
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.037
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.037
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.036
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.036
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.035
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
5 |
0.035
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.034
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.034
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.034
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.034
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.033
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.033
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.033
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.033
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.033
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.033
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.033
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.033
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.033
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.032
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.032
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
2 |
0.032
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.032
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.032
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.032
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.032
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.032
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.032
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.032
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.031
|
|
|
|
iris morphogenesis
|
GO:0061072 |
2 |
0.031
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.031
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.031
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.031
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.030
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.030
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
16 |
0.030
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.030
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.030
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.030
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.030
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.030
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.030
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.030
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.030
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.030
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.030
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.030
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.029
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.029
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.029
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.029
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.029
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.029
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.029
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.029
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.028
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.028
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.028
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.028
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.028
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.028
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.028
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.028
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.028
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.027
|
|
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.027
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.027
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.027
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.027
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.027
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.027
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.027
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.026
|
|
|
|
head development
|
GO:0060322 |
108 |
0.026
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.026
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.026
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.026
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.026
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.026
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.026
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.026
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.026
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.026
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.026
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.026
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.026
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.026
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.026
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.025
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.025
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.025
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.025
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.025
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.025
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.025
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.025
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.025
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.025
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.025
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.025
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.025
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.025
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.025
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.025
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.024
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.024
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.024
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.024
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.024
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.024
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.024
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.024
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.024
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.023
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.023
|
|
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.023
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.023
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.023
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.023
|
|
|
|
ruffle organization
|
GO:0031529 |
18 |
0.023
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.023
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.023
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.022
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.022
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.022
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.022
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.022
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.022
|
|
