Homo sapiens

44 known processes

THOC2

THO complex 2

(Aliases: hTREX120,CXorf3,dJ506G2.1,THO2)

THOC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna transport GO:0050658 39 0.994
nucleobase containing compound transport GO:0015931 51 0.981
mrna transport GO:0051028 30 0.973
mrna export from nucleus GO:0006406 29 0.967
viral mrna export from host cell nucleus GO:0046784 8 0.951
establishment of rna localization GO:0051236 39 0.892
replication fork processing GO:0031297 13 0.892
intracellular transport of virus GO:0075733 14 0.880
nucleic acid transport GO:0050657 39 0.860
transport of virus GO:0046794 14 0.829
nitrogen compound transport GO:0071705 191 0.792
nuclear export GO:0051168 69 0.784
cellular response to dna damage stimulus GO:0006974 379 0.762
multi organism localization GO:1902579 14 0.756
interspecies interaction between organisms GO:0044419 156 0.715
cytoplasmic transport GO:0016482 379 0.713
nuclear transport GO:0051169 179 0.698
rna localization GO:0006403 41 0.663
nucleocytoplasmic transport GO:0006913 176 0.662
multi organism intracellular transport GO:1902583 14 0.624
chromatin modification GO:0016568 298 0.621
nucleoside monophosphate catabolic process GO:0009125 159 0.611
multi organism transport GO:0044766 14 0.596
viral life cycle GO:0019058 132 0.596
viral process GO:0016032 146 0.572
negative regulation of dna damage checkpoint GO:2000002 4 0.566
multi organism cellular process GO:0044764 156 0.550
negative regulation of cell cycle process GO:0010948 121 0.516
atp catabolic process GO:0006200 157 0.462
ribonucleoside triphosphate catabolic process GO:0009203 391 0.456
purine nucleoside monophosphate metabolic process GO:0009126 186 0.442
negative regulation of b cell mediated immunity GO:0002713 3 0.427
chromatin organization GO:0006325 351 0.403
cell cycle checkpoint GO:0000075 117 0.401
rna export from nucleus GO:0006405 33 0.400
glycosyl compound catabolic process GO:1901658 413 0.396
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.395
dna damage checkpoint GO:0000077 68 0.394
purine nucleotide catabolic process GO:0006195 405 0.388
negative regulation of cell cycle checkpoint GO:1901977 4 0.358
post embryonic development GO:0009791 2 0.350
Worm
nucleoside monophosphate metabolic process GO:0009123 191 0.340
regulation of response to dna damage stimulus GO:2001020 94 0.333
nucleoside phosphate catabolic process GO:1901292 412 0.329
regulation of cell cycle process GO:0010564 266 0.308
dna integrity checkpoint GO:0031570 71 0.293
ribonucleotide catabolic process GO:0009261 405 0.287
purine nucleoside catabolic process GO:0006152 398 0.284
mitotic cell cycle process GO:1903047 286 0.274
regulation of cell cycle GO:0051726 393 0.267
positive regulation of dna templated transcription elongation GO:0032786 18 0.261
dna repair GO:0006281 198 0.250
ribonucleoside monophosphate metabolic process GO:0009161 187 0.249
purine ribonucleotide catabolic process GO:0009154 404 0.234
regulation of dna damage checkpoint GO:2000001 9 0.226
purine nucleoside triphosphate catabolic process GO:0009146 392 0.210
nucleotide excision repair GO:0006289 31 0.201
chromatin remodeling GO:0006338 55 0.197
purine nucleoside monophosphate catabolic process GO:0009128 158 0.196
nucleoside catabolic process GO:0009164 408 0.192
nucleoside triphosphate metabolic process GO:0009141 422 0.185
ribonucleoside catabolic process GO:0042454 406 0.178
negative regulation of b cell activation GO:0050869 6 0.175
negative regulation of cell cycle GO:0045786 193 0.175
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.166
immune system development GO:0002520 195 0.164
positive regulation of cellular component organization GO:0051130 376 0.163
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.155
purine nucleoside triphosphate metabolic process GO:0009144 412 0.155
purine ribonucleoside metabolic process GO:0046128 437 0.151
regulation of dna templated transcription elongation GO:0032784 23 0.147
negative regulation of programmed cell death GO:0043069 321 0.140
ribonucleoside triphosphate metabolic process GO:0009199 412 0.135
purine containing compound catabolic process GO:0072523 411 0.135
dna templated transcription elongation GO:0006354 25 0.131
negative regulation of developmental process GO:0051093 247 0.129
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.129
purine ribonucleoside catabolic process GO:0046130 398 0.119
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.116
organophosphate catabolic process GO:0046434 430 0.115
rna processing GO:0006396 255 0.111
dna replication GO:0006260 116 0.109
ribonucleoside monophosphate catabolic process GO:0009158 158 0.108
atp metabolic process GO:0046034 176 0.108
nucleoside triphosphate catabolic process GO:0009143 394 0.103
embryo development GO:0009790 123 0.103
Worm
mrna processing GO:0006397 133 0.095
response to abiotic stimulus GO:0009628 336 0.091
negative regulation of protein metabolic process GO:0051248 391 0.091
microtubule based process GO:0007017 210 0.090
translation GO:0006412 132 0.086
immune response GO:0006955 307 0.085
dna dependent dna replication GO:0006261 44 0.084
ribonucleoprotein complex assembly GO:0022618 78 0.083
spindle organization GO:0007051 53 0.078
regulation of cellular response to stress GO:0080135 244 0.077
dna recombination GO:0006310 77 0.077
microtubule cytoskeleton organization GO:0000226 176 0.077
nucleotide catabolic process GO:0009166 408 0.076
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.075
ribonucleoprotein complex biogenesis GO:0022613 116 0.074
negative regulation of phosphate metabolic process GO:0045936 267 0.074
reproductive process GO:0022414 106 0.071
Worm
negative regulation of cell death GO:0060548 345 0.069
regulation of immune response GO:0050776 201 0.069
cell cycle phase transition GO:0044770 173 0.069
regulation of isotype switching GO:0045191 2 0.069
protein localization to organelle GO:0033365 280 0.068
ribonucleoprotein complex subunit organization GO:0071826 81 0.068
positive regulation of catabolic process GO:0009896 310 0.064
positive regulation of organelle organization GO:0010638 195 0.063
regulation of cellular amine metabolic process GO:0033238 11 0.063
regulation of purine nucleotide metabolic process GO:1900542 264 0.061
negative regulation of phosphorus metabolic process GO:0010563 267 0.058
regulation of cell cycle checkpoint GO:1901976 21 0.058
regulation of mrna metabolic process GO:1903311 53 0.057
translational initiation GO:0006413 48 0.056
reproductive system development GO:0061458 56 0.056
Worm
hematopoietic or lymphoid organ development GO:0048534 186 0.054
negative regulation of apoptotic process GO:0043066 316 0.053
negative regulation of catalytic activity GO:0043086 335 0.052
negative regulation of hydrolase activity GO:0051346 182 0.052
negative regulation of immune system process GO:0002683 136 0.051
positive regulation of transport GO:0051050 336 0.051
positive regulation of mitosis GO:0045840 25 0.050
regulation of dna metabolic process GO:0051052 153 0.050
negative regulation of transport GO:0051051 176 0.050
posttranscriptional regulation of gene expression GO:0010608 213 0.050
determination of adult lifespan GO:0008340 2 0.049
regulation of dna recombination GO:0000018 23 0.049
rna splicing via transesterification reactions GO:0000375 90 0.048
embryonic placenta development GO:0001892 1 0.047
regulation of protein localization GO:0032880 296 0.047
signal transduction by phosphorylation GO:0023014 297 0.046
regulation of atp metabolic process GO:1903578 29 0.046
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.044
negative regulation of catabolic process GO:0009895 104 0.044
protein targeting GO:0006605 187 0.044
cell projection organization GO:0030030 252 0.043
regulation of b cell activation GO:0050864 24 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.041
negative regulation of response to dna damage stimulus GO:2001021 33 0.040
single organism cellular localization GO:1902580 332 0.040
mrna 3 end processing GO:0031124 24 0.040
innate immune response GO:0045087 178 0.038
spermatid differentiation GO:0048515 4 0.037
intracellular protein transport GO:0006886 270 0.037
cellular macromolecule catabolic process GO:0044265 380 0.037
mitotic cell cycle phase transition GO:0044772 162 0.036
cell division GO:0051301 168 0.036
negative regulation of protein processing GO:0010955 142 0.035
establishment of protein localization to organelle GO:0072594 172 0.035
immune effector process GO:0002252 159 0.035
positive regulation of cell cycle process GO:0090068 106 0.035
regulation of nucleotide metabolic process GO:0006140 269 0.034
regulation of gene expression epigenetic GO:0040029 73 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
rna 3 end processing GO:0031123 35 0.034
negative regulation of cellular catabolic process GO:0031330 83 0.034
positive regulation of cell division GO:0051781 59 0.032
regulation of cell division GO:0051302 116 0.032
positive regulation of cell cycle GO:0045787 140 0.032
hemopoiesis GO:0030097 180 0.032
protein dna complex subunit organization GO:0071824 80 0.031
negative regulation of immune response GO:0050777 40 0.031
negative regulation of mitotic cell cycle GO:0045930 102 0.030
mapk cascade GO:0000165 288 0.030
negative regulation of production of molecular mediator of immune response GO:0002701 13 0.030
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.030
multicellular organismal aging GO:0010259 3 0.030
positive regulation of intracellular protein transport GO:0090316 76 0.030
mitotic cell cycle GO:0000278 326 0.029
regulation of translation GO:0006417 89 0.029
mitotic spindle organization GO:0007052 27 0.029
neurogenesis GO:0022008 169 0.029
nervous system development GO:0007399 293 0.028
single organism reproductive process GO:0044702 98 0.028
Worm
central nervous system development GO:0007417 123 0.027
embryo development ending in birth or egg hatching GO:0009792 34 0.027
Worm
cellular response to oxygen containing compound GO:1901701 276 0.027
protein maturation GO:0051604 233 0.027
amine metabolic process GO:0009308 44 0.027
regulation of protein transport GO:0051223 213 0.027
response to external biotic stimulus GO:0043207 261 0.026
cellular ketone metabolic process GO:0042180 80 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
regulation of proteolysis GO:0030162 293 0.025
vesicle mediated transport GO:0016192 371 0.025
dna conformation change GO:0071103 113 0.025
apoptotic signaling pathway GO:0097190 268 0.025
regulation of mitotic cell cycle phase transition GO:1901990 118 0.024
rna splicing GO:0008380 131 0.024
regulation of immune effector process GO:0002697 91 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.024
actin filament based process GO:0030029 224 0.023
regulation of protein complex assembly GO:0043254 147 0.023
adaptive immune response GO:0002250 49 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
gene silencing GO:0016458 49 0.023
myeloid leukocyte differentiation GO:0002573 60 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
embryonic organ development GO:0048568 36 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
mrna splicing via spliceosome GO:0000398 89 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
female gamete generation GO:0007292 2 0.021
Worm
isotype switching GO:0045190 3 0.021
ossification GO:0001503 121 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of isotype switching to iga isotypes GO:0048296 2 0.020
defense response GO:0006952 315 0.020
myeloid cell differentiation GO:0030099 117 0.020
nuclear division GO:0000280 128 0.020
Worm
endocytosis GO:0006897 159 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
regulation of chromatin modification GO:1903308 51 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
lymphocyte activation GO:0046649 133 0.019
positive regulation of chromosome organization GO:2001252 41 0.019
regulation of atpase activity GO:0043462 25 0.019
response to organic cyclic compound GO:0014070 204 0.019
positive regulation of intracellular transport GO:0032388 104 0.018
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.018
regulation of innate immune response GO:0045088 97 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
regulation of leukocyte activation GO:0002694 115 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
negative regulation of immunoglobulin mediated immune response GO:0002890 3 0.018
cell projection morphogenesis GO:0048858 129 0.017
positive regulation of protein transport GO:0051222 135 0.017
brain development GO:0007420 97 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
nuclear import GO:0051170 106 0.017
negative regulation of proteolysis GO:0045861 132 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
reproductive structure development GO:0048608 55 0.017
Worm
regulation of atp catabolic process GO:1903289 25 0.017
regulation of chromosome organization GO:0033044 103 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
oogenesis GO:0048477 2 0.016
Worm
regulation of protein maturation GO:1903317 150 0.016
cellular protein catabolic process GO:0044257 261 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
mitotic nuclear division GO:0007067 119 0.016
regulation of protein import into nucleus GO:0042306 78 0.016
protein processing GO:0016485 226 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.016
response to biotic stimulus GO:0009607 276 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.016
rrna metabolic process GO:0016072 40 0.016
protein localization to nucleus GO:0034504 136 0.016
response to growth factor GO:0070848 205 0.016
growth GO:0040007 202 0.015
regulation of rna splicing GO:0043484 62 0.015
positive regulation of protein localization to nucleus GO:1900182 48 0.015
regulation of cell differentiation GO:0045595 393 0.015
cytokinesis GO:0000910 96 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
neuron differentiation GO:0030182 138 0.015
regulation of translational initiation GO:0006446 24 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.015
developmental process involved in reproduction GO:0003006 66 0.015
Worm
regulation of mrna processing GO:0050684 48 0.015
methylation GO:0032259 106 0.015
cell development GO:0048468 328 0.015
Worm
locomotory behavior GO:0007626 1 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
response to radiation GO:0009314 151 0.014
organelle fission GO:0048285 149 0.014
Worm
cellular component morphogenesis GO:0032989 314 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
cell morphogenesis GO:0000902 296 0.014
response to oxygen containing compound GO:1901700 369 0.014
sister chromatid segregation GO:0000819 54 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
meiosis i GO:0007127 4 0.014
jak stat cascade GO:0007259 46 0.014
response to hormone GO:0009725 175 0.014
alternative mrna splicing via spliceosome GO:0000380 27 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
protein catabolic process GO:0030163 325 0.013
cell activation GO:0001775 213 0.013
production of molecular mediator of immune response GO:0002440 37 0.013
negative regulation of protein maturation GO:1903318 142 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
protein autophosphorylation GO:0046777 123 0.013
leukocyte activation GO:0045321 164 0.013
generation of neurons GO:0048699 152 0.013
response to nitrogen compound GO:1901698 184 0.013
negative regulation of gene expression epigenetic GO:0045814 19 0.013
membrane organization GO:0061024 292 0.013
rrna processing GO:0006364 35 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
head development GO:0060322 108 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
immunoglobulin mediated immune response GO:0016064 10 0.012
spliceosomal complex assembly GO:0000245 17 0.012
mitotic sister chromatid separation GO:0051306 18 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of canonical wnt signaling pathway GO:0060828 88 0.012
histone modification GO:0016570 251 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
system process GO:0003008 349 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.012
anatomical structure homeostasis GO:0060249 100 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
reproduction GO:0000003 63 0.012
Worm
regulation of protein processing GO:0070613 150 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.011
leukocyte differentiation GO:0002521 98 0.011
regulation of protein catabolic process GO:0042176 155 0.011
protein targeting to nucleus GO:0044744 104 0.011
response to other organism GO:0051707 261 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
trabecula morphogenesis GO:0061383 2 0.011
negative regulation of chromosome organization GO:2001251 48 0.011
ncrna processing GO:0034470 83 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
angiogenesis GO:0001525 147 0.010
oocyte development GO:0048599 1 0.010
cytoplasmic translational initiation GO:0002183 6 0.010
aging GO:0007568 66 0.010
organelle assembly GO:0070925 176 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010

THOC2 disease predictions

Disease DO term ID Size Probability Func Analog Org
joubert syndrome DOID:0050777 18 0.053