Homo sapiens

17 known processes

COPS3

COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)

(Aliases: SGN3,CSN3)

COPS3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cullin deneddylation GO:0010388 9 0.947
post embryonic development GO:0009791 2 0.914
g2 dna damage checkpoint GO:0031572 26 0.785
Fly
protein deneddylation GO:0000338 10 0.776
regulation of mitotic cell cycle phase transition GO:1901990 118 0.740
Fly
cellular macromolecule catabolic process GO:0044265 380 0.645
Worm
regulation of mitotic cell cycle GO:0007346 189 0.584
Fly
cellular response to dna damage stimulus GO:0006974 379 0.572
Fly
regulation of cell cycle phase transition GO:1901987 126 0.568
Fly
protein modification by small protein removal GO:0070646 92 0.543
regulation of cell cycle GO:0051726 393 0.524
Fly
mitotic cell cycle process GO:1903047 286 0.511
Worm Fly
dna integrity checkpoint GO:0031570 71 0.453
Fly
mitotic cell cycle checkpoint GO:0007093 68 0.435
Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.431
Worm
embryo development GO:0009790 123 0.401
Mouse
negative regulation of mitotic cell cycle GO:0045930 102 0.372
Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.356
Fly
mitotic dna damage checkpoint GO:0044773 28 0.343
Fly
mitotic cell cycle phase transition GO:0044772 162 0.302
Fly
cell cycle checkpoint GO:0000075 117 0.294
Fly
cell cell signaling involved in cell fate commitment GO:0045168 5 0.293
Fly
protein processing GO:0016485 226 0.293
regulation of cell cycle process GO:0010564 266 0.260
Fly
reproductive system development GO:0061458 56 0.259
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.247
Worm
protein catabolic process GO:0030163 325 0.232
Worm
nervous system development GO:0007399 293 0.221
vesicle mediated transport GO:0016192 371 0.220
cellular protein catabolic process GO:0044257 261 0.216
Worm
negative regulation of cell cycle process GO:0010948 121 0.213
Fly
negative regulation of cell cycle GO:0045786 193 0.210
Fly
reproductive structure development GO:0048608 55 0.202
organelle fission GO:0048285 149 0.179
gonad development GO:0008406 34 0.179
mitotic g2 m transition checkpoint GO:0044818 9 0.163
Fly
dna damage checkpoint GO:0000077 68 0.163
Fly
mitotic cell cycle GO:0000278 326 0.155
Worm Fly
mitotic dna integrity checkpoint GO:0044774 30 0.152
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.151
Fly
positive regulation of protein phosphorylation GO:0001934 313 0.148
sex differentiation GO:0007548 45 0.123
cell cycle phase transition GO:0044770 173 0.120
Fly
proteasomal protein catabolic process GO:0010498 176 0.117
modification dependent protein catabolic process GO:0019941 209 0.116
Worm
mrna metabolic process GO:0016071 175 0.111
multicellular organismal aging GO:0010259 3 0.109
segmentation GO:0035282 4 0.104
reproductive process GO:0022414 106 0.099
developmental process involved in reproduction GO:0003006 66 0.096
regulation of protein catabolic process GO:0042176 155 0.094
positive regulation of phosphorylation GO:0042327 394 0.089
reproduction GO:0000003 63 0.085
purine ribonucleoside metabolic process GO:0046128 437 0.082
negative regulation of catabolic process GO:0009895 104 0.082
ribonucleoside monophosphate metabolic process GO:0009161 187 0.082
posttranscriptional regulation of gene expression GO:0010608 213 0.078
Fly
single organism reproductive process GO:0044702 98 0.075
negative regulation of cell proliferation GO:0008285 228 0.073
modification dependent macromolecule catabolic process GO:0043632 212 0.072
Worm
regulation of cellular protein catabolic process GO:1903362 96 0.071
determination of adult lifespan GO:0008340 2 0.071
negative regulation of cellular catabolic process GO:0031330 83 0.063
neurogenesis GO:0022008 169 0.063
response to abiotic stimulus GO:0009628 336 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.059
multicellular organism reproduction GO:0032504 42 0.059
regulation of proteolysis GO:0030162 293 0.058
positive regulation of catabolic process GO:0009896 310 0.057
protein modification by small protein conjugation GO:0032446 342 0.056
adult locomotory behavior GO:0008344 1 0.056
cell development GO:0048468 328 0.055
cell division GO:0051301 168 0.055
Worm
response to radiation GO:0009314 151 0.053
development of primary sexual characteristics GO:0045137 35 0.052
neuron differentiation GO:0030182 138 0.044
apoptotic signaling pathway GO:0097190 268 0.042
anterior posterior axis specification GO:0009948 2 0.041
regulation of transferase activity GO:0051338 355 0.041
regulation of proteasomal protein catabolic process GO:0061136 87 0.039
endocytosis GO:0006897 159 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
positive regulation of transferase activity GO:0051347 227 0.038
cyclin catabolic process GO:0008054 6 0.038
cell cell signaling GO:0007267 155 0.037
Fly
internal protein amino acid acetylation GO:0006475 101 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
intracellular protein transport GO:0006886 270 0.035
neuromuscular junction development GO:0007528 3 0.034
protein polyubiquitination GO:0000209 110 0.033
regulation of mitosis GO:0007088 63 0.032
cellular amine metabolic process GO:0044106 41 0.032
cellular macromolecular complex assembly GO:0034622 324 0.032
nuclear transport GO:0051169 179 0.031
embryo development ending in birth or egg hatching GO:0009792 34 0.031
Mouse
protein deubiquitination GO:0016579 79 0.030
regulation of protein maturation GO:1903317 150 0.029
regulation of cellular response to stress GO:0080135 244 0.029
nik nf kappab signaling GO:0038061 12 0.029
meiotic chromosome segregation GO:0045132 4 0.029
positive regulation of protein catabolic process GO:0045732 75 0.028
generation of neurons GO:0048699 152 0.026
multicellular organismal reproductive process GO:0048609 40 0.025
regulation of protein stability GO:0031647 87 0.025
Fly
tripartite regional subdivision GO:0007351 2 0.025
negative regulation of protein processing GO:0010955 142 0.025
nuclear division GO:0000280 128 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
regulation of protein kinase activity GO:0045859 289 0.024
receptor mediated endocytosis GO:0006898 84 0.023
protein maturation GO:0051604 233 0.023
regulation of nucleocytoplasmic transport GO:0046822 98 0.023
cytokinesis GO:0000910 96 0.023
Worm
positive regulation of transport GO:0051050 336 0.023
mitotic nuclear division GO:0007067 119 0.023
sister chromatid segregation GO:0000819 54 0.022
chromosome segregation GO:0007059 114 0.022
protein acetylation GO:0006473 116 0.022
chromatin organization GO:0006325 351 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
blastoderm segmentation GO:0007350 2 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
locomotory behavior GO:0007626 1 0.021
cell fate commitment GO:0045165 27 0.021
Fly
dna repair GO:0006281 198 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
dna conformation change GO:0071103 113 0.020
negative regulation of cellular component organization GO:0051129 235 0.019
regeneration GO:0031099 4 0.019
ribonucleotide biosynthetic process GO:0009260 81 0.019
negative regulation of protein maturation GO:1903318 142 0.019
protein dna complex subunit organization GO:0071824 80 0.019
protein stabilization GO:0050821 64 0.018
Fly
single organism cellular localization GO:1902580 332 0.018
Worm
oocyte development GO:0048599 1 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
chromatin modification GO:0016568 298 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
protein import into nucleus GO:0006606 104 0.017
behavior GO:0007610 112 0.017
rna splicing GO:0008380 131 0.017
protein targeting to nucleus GO:0044744 104 0.016
histone modification GO:0016570 251 0.016
gene silencing by rna GO:0031047 26 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
oogenesis GO:0048477 2 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
response to light stimulus GO:0009416 87 0.015
regulation of kinase activity GO:0043549 314 0.015
neuron development GO:0048666 113 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.015
action potential GO:0001508 34 0.015
aging GO:0007568 66 0.015
regulation of locomotion GO:0040012 329 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.015
response to hormone GO:0009725 175 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.014
stress activated mapk cascade GO:0051403 93 0.014
cell morphogenesis GO:0000902 296 0.014
spindle organization GO:0007051 53 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
protein autophosphorylation GO:0046777 123 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
positive regulation of cell death GO:0010942 263 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
cellular response to radiation GO:0071478 65 0.014
response to virus GO:0009615 126 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.013
pattern specification process GO:0007389 43 0.013
amine metabolic process GO:0009308 44 0.013
response to other organism GO:0051707 261 0.013
regulation of growth GO:0040008 165 0.013
peptidyl lysine modification GO:0018205 144 0.013
mapk cascade GO:0000165 288 0.012
negative regulation of protein catabolic process GO:0042177 59 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
protein dna complex assembly GO:0065004 64 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
negative regulation of cellular protein catabolic process GO:1903363 38 0.012
nucleosome organization GO:0034728 66 0.012
positive regulation of kinase activity GO:0033674 204 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
gene silencing GO:0016458 49 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
cytokine production GO:0001816 247 0.011
nuclear transcribed mrna catabolic process GO:0000956 48 0.011
protein import into mitochondrial matrix GO:0030150 1 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
nitrogen compound transport GO:0071705 191 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
protein import GO:0017038 130 0.011
single organism nuclear import GO:1902593 104 0.011
positive regulation of cell cycle GO:0045787 140 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
biological adhesion GO:0022610 331 0.011
regulation of intracellular transport GO:0032386 195 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
phagocytosis GO:0006909 42 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
nuclear import GO:0051170 106 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.010
protein localization to organelle GO:0033365 280 0.010
single organism membrane organization GO:0044802 268 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
regionalization GO:0003002 29 0.010
multi organism reproductive process GO:0044703 54 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
regulation of protein localization GO:0032880 296 0.010
microtubule based process GO:0007017 210 0.010
Worm

COPS3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.016
eye and adnexa disease DOID:1492 150 0.016
nervous system disease DOID:863 431 0.016
eye disease DOID:5614 149 0.016