Homo sapiens

479 known processes

IGF1

insulin-like growth factor 1 (somatomedin C)

(Aliases: IGF1A,IGFI,IGF-I)

IGF1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
enzyme linked receptor protein signaling pathway GO:0007167 303 0.753
regulation of cell migration GO:0030334 289 0.645
positive regulation of mapk cascade GO:0043410 190 0.596
cellular response to oxygen containing compound GO:1901701 276 0.520
Human
regulation of locomotion GO:0040012 329 0.512
positive regulation of developmental process GO:0051094 314 0.494
negative regulation of locomotion GO:0040013 118 0.492
positive regulation of protein phosphorylation GO:0001934 313 0.489
regulation of cell motility GO:2000145 299 0.488
regulation of cellular component movement GO:0051270 334 0.471
cellular response to endogenous stimulus GO:0071495 336 0.457
Human
positive regulation of protein kinase activity GO:0045860 190 0.455
Human
blood vessel development GO:0001568 172 0.453
regulation of mapk cascade GO:0043408 262 0.440
cell adhesion GO:0007155 325 0.393
mapk cascade GO:0000165 288 0.392
negative regulation of developmental process GO:0051093 247 0.388
positive regulation of cell differentiation GO:0045597 211 0.382
signal transduction by phosphorylation GO:0023014 297 0.375
response to oxygen containing compound GO:1901700 369 0.362
Human
circulatory system development GO:0072359 262 0.358
Mouse
blood vessel morphogenesis GO:0048514 162 0.336
regulation of transferase activity GO:0051338 355 0.334
Human
positive regulation of transferase activity GO:0051347 227 0.320
Human
response to wounding GO:0009611 168 0.314
response to organonitrogen compound GO:0010243 156 0.302
Human
wound healing GO:0042060 115 0.266
cardiovascular system development GO:0072358 262 0.251
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.250
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.242
negative regulation of cell migration GO:0030336 102 0.240
regulation of cell differentiation GO:0045595 393 0.235
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.234
monocarboxylic acid metabolic process GO:0032787 185 0.228
cellular ketone metabolic process GO:0042180 80 0.225
Human
ossification GO:0001503 121 0.223
activation of protein kinase activity GO:0032147 90 0.222
Human
response to lipid GO:0033993 206 0.221
angiogenesis GO:0001525 147 0.213
response to organic cyclic compound GO:0014070 204 0.210
positive regulation of cellular component organization GO:0051130 376 0.209
positive regulation of cellular component movement GO:0051272 181 0.208
positive regulation of cellular amine metabolic process GO:0033240 7 0.204
regulation of response to external stimulus GO:0032101 222 0.197
Human
cellular lipid metabolic process GO:0044255 303 0.194
Human
negative regulation of cell motility GO:2000146 104 0.194
muscle cell proliferation GO:0033002 35 0.192
positive regulation of phosphorylation GO:0042327 394 0.191
negative regulation of cellular component movement GO:0051271 106 0.185
positive regulation of kinase activity GO:0033674 204 0.183
Human
lipid metabolic process GO:0006629 381 0.182
Human
cellular amine metabolic process GO:0044106 41 0.180
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.179
ras protein signal transduction GO:0007265 73 0.173
regulation of cellular amine metabolic process GO:0033238 11 0.172
Human
positive regulation of cell proliferation GO:0008284 301 0.171
chemical homeostasis GO:0048878 306 0.171
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.169
Human
nervous system development GO:0007399 293 0.164
Mouse
regulation of kinase activity GO:0043549 314 0.159
Human
positive regulation of apoptotic process GO:0043065 246 0.159
regulation of cellular amino acid metabolic process GO:0006521 6 0.156
Human
regulation of cell adhesion GO:0030155 166 0.155
cell development GO:0048468 328 0.154
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.153
negative regulation of cell proliferation GO:0008285 228 0.153
Mouse
positive regulation of programmed cell death GO:0043068 249 0.152
system process GO:0003008 349 0.150
small gtpase mediated signal transduction GO:0007264 78 0.150
positive regulation of locomotion GO:0040017 186 0.145
cell type specific apoptotic process GO:0097285 125 0.142
blood circulation GO:0008015 113 0.141
response to nitrogen compound GO:1901698 184 0.141
Human
cytokine production GO:0001816 247 0.140
Human
amine metabolic process GO:0009308 44 0.140
Human
vasculature development GO:0001944 181 0.137
Mouse
response to abiotic stimulus GO:0009628 336 0.134
response to growth factor GO:0070848 205 0.133
smooth muscle cell proliferation GO:0048659 28 0.131
cellular response to nitrogen compound GO:1901699 144 0.129
Human
regulation of protein kinase activity GO:0045859 289 0.127
Human
positive regulation of cell motility GO:2000147 177 0.126
cyclic nucleotide metabolic process GO:0009187 82 0.126
actin filament based process GO:0030029 224 0.124
cell substrate adhesion GO:0031589 132 0.124
positive regulation of cell death GO:0010942 263 0.121
negative regulation of protein metabolic process GO:0051248 391 0.117
Human
regulation of cell development GO:0060284 161 0.115
Human
epithelium development GO:0060429 227 0.114
Mouse
regulation of vasculature development GO:1901342 97 0.113
negative regulation of phosphate metabolic process GO:0045936 267 0.106
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.105
negative regulation of cell differentiation GO:0045596 171 0.104
positive regulation of transport GO:0051050 336 0.104
innate immune response GO:0045087 178 0.103
Human
regulation of cytokine production GO:0001817 232 0.102
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.101
Mouse
immune response GO:0006955 307 0.100
Human
cellular amino acid metabolic process GO:0006520 116 0.097
Human
tissue morphogenesis GO:0048729 96 0.097
Mouse
biological adhesion GO:0022610 331 0.096
response to other organism GO:0051707 261 0.095
fatty acid metabolic process GO:0006631 115 0.094
Human
response to cytokine GO:0034097 232 0.091
actin cytoskeleton organization GO:0030036 207 0.091
positive regulation of immune system process GO:0002684 283 0.088
growth GO:0040007 202 0.087
carbohydrate metabolic process GO:0005975 207 0.087
regulation of cellular response to stress GO:0080135 244 0.084
cellular response to organonitrogen compound GO:0071417 124 0.084
Human
negative regulation of cell death GO:0060548 345 0.082
regulation of protein serine threonine kinase activity GO:0071900 179 0.080
peptidyl tyrosine modification GO:0018212 170 0.078
positive regulation of map kinase activity GO:0043406 80 0.078
ion homeostasis GO:0050801 230 0.078
Human
reactive oxygen species metabolic process GO:0072593 75 0.078
cellular response to organic cyclic compound GO:0071407 127 0.078
rho protein signal transduction GO:0007266 26 0.077
defense response GO:0006952 315 0.076
Human
regulation of cellular component biogenesis GO:0044087 281 0.076
Human
positive regulation of stress activated mapk cascade GO:0032874 60 0.076
regulation of protein processing GO:0070613 150 0.073
Human
lipid biosynthetic process GO:0008610 177 0.071
regulation of angiogenesis GO:0045765 92 0.071
cell activation GO:0001775 213 0.071
cell morphogenesis GO:0000902 296 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.070
single organism cell adhesion GO:0098602 179 0.069
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.067
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.067
cellular cation homeostasis GO:0030003 163 0.066
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.065
regulation of smooth muscle cell proliferation GO:0048660 28 0.065
negative regulation of cell adhesion GO:0007162 64 0.063
regulation of cell growth GO:0001558 135 0.063
cell chemotaxis GO:0060326 112 0.062
regulation of stress activated mapk cascade GO:0032872 84 0.062
regulation of actin filament based process GO:0032970 141 0.062
female gamete generation GO:0007292 2 0.061
cell growth GO:0016049 160 0.061
regulation of small gtpase mediated signal transduction GO:0051056 156 0.060
negative regulation of catalytic activity GO:0043086 335 0.060
Human
muscle structure development GO:0061061 98 0.060
positive regulation of jnk cascade GO:0046330 52 0.060
negative regulation of smooth muscle cell migration GO:0014912 7 0.060
single organism carbohydrate metabolic process GO:0044723 193 0.060
protein processing GO:0016485 226 0.060
Human
chemotaxis GO:0006935 157 0.058
tissue migration GO:0090130 119 0.058
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.058
regulation of protein maturation GO:1903317 150 0.058
Human
segmentation GO:0035282 4 0.058
cellular divalent inorganic cation homeostasis GO:0072503 128 0.057
positive regulation of cell development GO:0010720 92 0.057
jnk cascade GO:0007254 80 0.057
extracellular matrix organization GO:0030198 41 0.057
response to hormone GO:0009725 175 0.056
Human
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.056
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.056
glycerolipid metabolic process GO:0046486 107 0.056
regulation of reactive oxygen species metabolic process GO:2000377 41 0.056
cellular component morphogenesis GO:0032989 314 0.055
cation homeostasis GO:0055080 189 0.055
cellular chemical homeostasis GO:0055082 180 0.055
negative regulation of apoptotic process GO:0043066 316 0.055
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.055
response to external biotic stimulus GO:0043207 261 0.055
g protein coupled receptor signaling pathway GO:0007186 207 0.054
Human
nucleotide catabolic process GO:0009166 408 0.053
regulation of smooth muscle cell migration GO:0014910 15 0.053
neurological system process GO:0050877 163 0.052
cellular metal ion homeostasis GO:0006875 146 0.051
locomotory behavior GO:0007626 1 0.051
activation of mapk activity GO:0000187 45 0.051
purine nucleotide catabolic process GO:0006195 405 0.051
negative regulation of angiogenesis GO:0016525 39 0.050
response to steroid hormone GO:0048545 80 0.050
cell projection organization GO:0030030 252 0.050
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.050
cellular ion homeostasis GO:0006873 168 0.050
regulation of jnk cascade GO:0046328 73 0.050
humoral immune response GO:0006959 49 0.049
muscle tissue development GO:0060537 62 0.049
regulation of nucleotide metabolic process GO:0006140 269 0.048
extracellular structure organization GO:0043062 41 0.048
vesicle mediated transport GO:0016192 371 0.047
response to biotic stimulus GO:0009607 276 0.047
purine containing compound catabolic process GO:0072523 411 0.047
stress activated mapk cascade GO:0051403 93 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.046
negative regulation of epithelial cell migration GO:0010633 38 0.045
inflammatory response GO:0006954 79 0.045
Human
regulation of map kinase activity GO:0043405 108 0.045
erk1 and erk2 cascade GO:0070371 104 0.045
Mouse
response to purine containing compound GO:0014074 40 0.045
muscle cell migration GO:0014812 19 0.044
peptidyl tyrosine phosphorylation GO:0018108 170 0.044
osteoblast differentiation GO:0001649 92 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.044
Human
negative regulation of protein phosphorylation GO:0001933 140 0.044
regulation of establishment of protein localization GO:0070201 242 0.044
central nervous system development GO:0007417 123 0.044
Mouse
regulation of actin cytoskeleton organization GO:0032956 116 0.044
cell morphogenesis involved in differentiation GO:0000904 144 0.043
taxis GO:0042330 157 0.043
regulation of behavior GO:0050795 82 0.043
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.043
maintenance of location GO:0051235 112 0.042
positive regulation of gtp catabolic process GO:0033126 166 0.042
ribonucleotide catabolic process GO:0009261 405 0.042
regulation of erk1 and erk2 cascade GO:0070372 99 0.042
Mouse
organophosphate catabolic process GO:0046434 430 0.042
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.042
positive regulation of catabolic process GO:0009896 310 0.041
purine nucleoside catabolic process GO:0006152 398 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
cellular homeostasis GO:0019725 196 0.041
circulatory system process GO:0003013 113 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
negative regulation of ectodermal cell fate specification GO:0042666 1 0.041
regulation of cellular response to growth factor stimulus GO:0090287 76 0.040
neurogenesis GO:0022008 169 0.040
Mouse
protein maturation GO:0051604 233 0.040
Human
negative regulation of cellular extravasation GO:0002692 5 0.040
bone mineralization GO:0030282 34 0.040
negative regulation of transport GO:0051051 176 0.040
Human
cellular carbohydrate metabolic process GO:0044262 84 0.039
regulation of protein localization GO:0032880 296 0.038
regulation of cell projection organization GO:0031344 107 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
regulation of endothelial cell migration GO:0010594 67 0.038
negative regulation of protein modification process GO:0031400 200 0.038
regeneration GO:0031099 4 0.038
tube development GO:0035295 125 0.037
Mouse
organic hydroxy compound metabolic process GO:1901615 147 0.037
cell matrix adhesion GO:0007160 85 0.037
luteolysis GO:0001554 3 0.037
mitotic cell cycle process GO:1903047 286 0.037
immune effector process GO:0002252 159 0.037
Human
response to organophosphorus GO:0046683 41 0.037
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.037
regulation of homeostatic process GO:0032844 121 0.037
regulation of epithelial cell proliferation GO:0050678 113 0.037
positive regulation of immune response GO:0050778 159 0.036
regulation of chemotaxis GO:0050920 74 0.036
lipid transport GO:0006869 90 0.036
regulation of response to wounding GO:1903034 101 0.036
Human
metal ion homeostasis GO:0055065 169 0.035
monosaccharide metabolic process GO:0005996 74 0.035
apoptotic signaling pathway GO:0097190 268 0.035
cation transport GO:0006812 331 0.035
generation of neurons GO:0048699 152 0.035
regulation of hormone levels GO:0010817 125 0.035
organic acid biosynthetic process GO:0016053 97 0.034
regulation of blood pressure GO:0008217 30 0.034
peripheral nervous system development GO:0007422 2 0.033
ion transmembrane transport GO:0034220 338 0.033
biomineral tissue development GO:0031214 39 0.033
hemostasis GO:0007599 76 0.033
negative regulation of phosphorylation GO:0042326 174 0.033
Mouse
ameboidal type cell migration GO:0001667 135 0.033
anion transport GO:0006820 161 0.033
coagulation GO:0050817 78 0.032
regulation of cell activation GO:0050865 125 0.032
negative regulation of embryonic development GO:0045992 4 0.032
carboxylic acid biosynthetic process GO:0046394 97 0.032
regulation of cell morphogenesis GO:0022604 153 0.032
negative regulation of gastrulation GO:2000542 4 0.032
negative regulation of programmed cell death GO:0043069 321 0.032
response to mechanical stimulus GO:0009612 51 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
lipid localization GO:0010876 106 0.032
bmp signaling pathway GO:0030509 49 0.032
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.032
glycosyl compound catabolic process GO:1901658 413 0.031
positive regulation of cell adhesion GO:0045785 84 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
motor neuron axon guidance GO:0008045 2 0.031
response to inorganic substance GO:0010035 127 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
spinal cord development GO:0021510 4 0.031
negative regulation of blood vessel morphogenesis GO:2000181 41 0.031
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.031
positive regulation of cell migration GO:0030335 172 0.031
divalent inorganic cation homeostasis GO:0072507 136 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
cellular response to hormone stimulus GO:0032870 125 0.030
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.030
regulation of immune response GO:0050776 201 0.030
Human
response to transforming growth factor beta GO:0071559 94 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.030
connective tissue development GO:0061448 39 0.030
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
regulation of blood vessel size GO:0050880 18 0.030
guanosine containing compound metabolic process GO:1901068 244 0.030
leukocyte chemotaxis GO:0030595 76 0.029
regulation of secretion GO:0051046 194 0.029
Human
steroid metabolic process GO:0008202 94 0.029
response to acid chemical GO:0001101 66 0.029
regulation of leukocyte chemotaxis GO:0002688 46 0.029
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 4 0.029
lipid catabolic process GO:0016042 84 0.029
regulation of nervous system development GO:0051960 88 0.028
Mouse
actin filament organization GO:0007015 128 0.028
cellular response to lipid GO:0071396 127 0.028
metal ion transport GO:0030001 272 0.028
oogenesis GO:0048477 2 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.028
post embryonic development GO:0009791 2 0.028
regulation of secretion by cell GO:1903530 177 0.028
Human
multicellular organismal aging GO:0010259 3 0.028
leukocyte proliferation GO:0070661 74 0.028
response to drug GO:0042493 81 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
regulation of cytoplasmic transport GO:1903649 149 0.028
cardiac right ventricle morphogenesis GO:0003215 3 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
cytoplasmic transport GO:0016482 379 0.027
cellular response to cytokine stimulus GO:0071345 181 0.027
secretion GO:0046903 254 0.027
Human
regulation of ion transport GO:0043269 189 0.027
regulation of rho protein signal transduction GO:0035023 79 0.027
salivary gland morphogenesis GO:0007435 4 0.027
oxidation reduction process GO:0055114 396 0.027
multicellular organismal macromolecule metabolic process GO:0044259 29 0.027
blood vessel endothelial cell migration GO:0043534 42 0.027
protein targeting GO:0006605 187 0.027
regulation of carbohydrate metabolic process GO:0006109 54 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
Human Mouse
positive regulation of organelle organization GO:0010638 195 0.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.026
regulation of neurogenesis GO:0050767 82 0.026
regulation of protein transport GO:0051223 213 0.026
endothelial cell migration GO:0043542 86 0.026
cell cell signaling GO:0007267 155 0.026
calcium ion homeostasis GO:0055074 122 0.026
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
positive regulation of odontogenesis GO:0042482 3 0.026
response to camp GO:0051591 25 0.026
muscle organ development GO:0007517 56 0.026
digestive tract morphogenesis GO:0048546 56 0.026
myeloid cell differentiation GO:0030099 117 0.026
regulation of sodium dependent phosphate transport GO:2000118 2 0.026
hemopoiesis GO:0030097 180 0.025
lipid modification GO:0030258 84 0.025
positive regulation of ras gtpase activity GO:0032320 117 0.025
reactive oxygen species biosynthetic process GO:1903409 4 0.025
regulation of cell substrate adhesion GO:0010810 68 0.025
striated muscle tissue development GO:0014706 59 0.025
morphogenesis of an epithelium GO:0002009 60 0.025
Mouse
sulfur compound metabolic process GO:0006790 101 0.025
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.025
positive regulation of behavior GO:0048520 60 0.025
positive regulation of angiogenesis GO:0045766 51 0.025
organ morphogenesis GO:0009887 147 0.025
Mouse
regulation of growth GO:0040008 165 0.025
protein activation cascade GO:0072376 22 0.025
response to oxygen levels GO:0070482 100 0.025
epithelial cell differentiation GO:0030855 141 0.025
Mouse
cytosolic calcium ion homeostasis GO:0051480 89 0.025
response to decreased oxygen levels GO:0036293 96 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
neuron differentiation GO:0030182 138 0.025
protein kinase b signaling GO:0043491 69 0.024
Human Mouse
guanosine containing compound catabolic process GO:1901069 239 0.024
kidney development GO:0001822 53 0.024
second messenger mediated signaling GO:0019932 78 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.024
memory GO:0007613 3 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.024
cellular response to camp GO:0071320 21 0.024
positive regulation of chemotaxis GO:0050921 57 0.024
positive regulation of ossification GO:0045778 32 0.024
blastoderm segmentation GO:0007350 2 0.024
organic anion transport GO:0015711 103 0.024
regulation of ras gtpase activity GO:0032318 128 0.024
anterior posterior axis specification GO:0009948 2 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
response to radiation GO:0009314 151 0.023
positive regulation of nervous system development GO:0051962 54 0.023
Mouse
tripartite regional subdivision GO:0007351 2 0.023
cell projection morphogenesis GO:0048858 129 0.023
regulation of axon guidance GO:1902667 3 0.023
negative regulation of vasculature development GO:1901343 43 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
Human
muscle system process GO:0003012 81 0.023
embryo development GO:0009790 123 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
Mouse
rhythmic behavior GO:0007622 2 0.023
regulation of wound healing GO:0061041 56 0.022
heart development GO:0007507 95 0.022
gtp metabolic process GO:0046039 239 0.022
regulation of proteolysis GO:0030162 293 0.022
Human
determination of adult lifespan GO:0008340 2 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
cellular response to abiotic stimulus GO:0071214 117 0.022
circadian behavior GO:0048512 2 0.022
inositol lipid mediated signaling GO:0048017 55 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
cell part morphogenesis GO:0032990 137 0.022
brain development GO:0007420 97 0.022
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
response to bacterium GO:0009617 144 0.022
secretion by cell GO:0032940 226 0.022
Human
hormone transport GO:0009914 68 0.022
regulation of anatomical structure size GO:0090066 101 0.022
lymphocyte proliferation GO:0046651 70 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.022
response to alcohol GO:0097305 64 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.022
epithelial cell migration GO:0010631 119 0.022
single organism cellular localization GO:1902580 332 0.022
sensory perception of pain GO:0019233 4 0.022
regulation of osteoblast differentiation GO:0045667 38 0.022
positive regulation of mononuclear cell proliferation GO:0032946 47 0.022
activation of immune response GO:0002253 114 0.021
single organism membrane organization GO:0044802 268 0.021
dephosphorylation GO:0016311 209 0.021
regulation of gtp catabolic process GO:0033124 180 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
gastrulation GO:0007369 51 0.021
protein autophosphorylation GO:0046777 123 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
regulation of cell cycle GO:0051726 393 0.021
cell projection assembly GO:0030031 126 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
nucleoside catabolic process GO:0009164 408 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.021
small molecule biosynthetic process GO:0044283 157 0.021
regulation of canonical wnt signaling pathway GO:0060828 88 0.020
epithelial cell proliferation GO:0050673 128 0.020
positive regulation of muscle cell differentiation GO:0051149 15 0.020
negative regulation of neutrophil chemotaxis GO:0090024 2 0.020
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.020
response to metal ion GO:0010038 84 0.020
cellular protein complex assembly GO:0043623 188 0.020
regulation of ion homeostasis GO:2000021 73 0.020
mitotic cell cycle GO:0000278 326 0.020
skin development GO:0043588 76 0.020
multicellular organismal metabolic process GO:0044236 34 0.020
intracellular protein transport GO:0006886 270 0.020
positive regulation of secretion GO:0051047 116 0.020
Human
regulation of system process GO:0044057 101 0.020
urogenital system development GO:0001655 65 0.020
Mouse
negative regulation of protein processing GO:0010955 142 0.020
Human
regulation of lipid metabolic process GO:0019216 96 0.020
Human
wnt signaling pathway GO:0016055 156 0.020
zymogen activation GO:0031638 70 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
regulation of glucose metabolic process GO:0010906 28 0.020
negative regulation of immune system process GO:0002683 136 0.019
Human
positive regulation of endothelial cell migration GO:0010595 39 0.019
positive regulation of proteolysis GO:0045862 142 0.019
immune system development GO:0002520 195 0.019
negative regulation of response to external stimulus GO:0032102 83 0.019
Human
response to extracellular stimulus GO:0009991 85 0.019
positive regulation of rho protein signal transduction GO:0035025 4 0.019
receptor metabolic process GO:0043112 81 0.019
protein localization to nucleus GO:0034504 136 0.019
regulation of blood coagulation GO:0030193 42 0.019
positive regulation of vasoconstriction GO:0045907 3 0.019
membrane organization GO:0061024 292 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.019
regulation of transmembrane transport GO:0034762 139 0.019
Human
protein localization to membrane GO:0072657 160 0.019
response to molecule of bacterial origin GO:0002237 82 0.019

IGF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.129
cardiovascular system disease DOID:1287 106 0.107
artery disease DOID:0050828 23 0.037
vascular disease DOID:178 25 0.037
disease of metabolism DOID:0014667 295 0.037
inherited metabolic disorder DOID:655 242 0.037
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
connective tissue disease DOID:65 109 0.025
central nervous system disease DOID:331 186 0.025
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
immune system disease DOID:2914 155 0.022
muscular disease DOID:0080000 114 0.021
organ system cancer DOID:0050686 164 0.021
eye and adnexa disease DOID:1492 150 0.020