Homo sapiens

6 known processes

DLD

dihydrolipoamide dehydrogenase

(Aliases: DLDH,LAD,GCSL,PHE3,E3)

DLD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.919
Mouse Rat
purine nucleoside triphosphate metabolic process GO:0009144 412 0.737
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.723
Mouse
post embryonic development GO:0009791 2 0.720
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.702
Mouse
nucleoside catabolic process GO:0009164 408 0.678
ribonucleoside monophosphate metabolic process GO:0009161 187 0.675
Mouse
thioester biosynthetic process GO:0035384 6 0.639
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.602
Mouse
acetyl coa metabolic process GO:0006084 8 0.576
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.529
ribonucleoside catabolic process GO:0042454 406 0.495
nucleoside monophosphate metabolic process GO:0009123 191 0.432
Mouse
determination of adult lifespan GO:0008340 2 0.416
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.415
purine nucleoside monophosphate metabolic process GO:0009126 186 0.393
Mouse
multicellular organismal aging GO:0010259 3 0.385
Worm
long chain fatty acid catabolic process GO:0042758 3 0.375
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.369
glycosyl compound catabolic process GO:1901658 413 0.346
organophosphate catabolic process GO:0046434 430 0.328
acyl coa metabolic process GO:0006637 23 0.306
Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.299
Mouse
purine containing compound catabolic process GO:0072523 411 0.295
ribonucleoside triphosphate catabolic process GO:0009203 391 0.279
lipid metabolic process GO:0006629 381 0.271
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.270
Mouse
ribonucleotide catabolic process GO:0009261 405 0.261
purine ribonucleoside catabolic process GO:0046130 398 0.260
generation of precursor metabolites and energy GO:0006091 68 0.219
Mouse
sulfur compound biosynthetic process GO:0044272 38 0.208
Rat
atp metabolic process GO:0046034 176 0.207
Mouse
purine nucleoside catabolic process GO:0006152 398 0.205
nucleotide catabolic process GO:0009166 408 0.196
mitochondrion organization GO:0007005 156 0.187
monocarboxylic acid metabolic process GO:0032787 185 0.183
Rat
apoptotic mitochondrial changes GO:0008637 57 0.155
lipid oxidation GO:0034440 33 0.154
cellular respiration GO:0045333 21 0.142
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.136
purine nucleotide catabolic process GO:0006195 405 0.131
response to organic cyclic compound GO:0014070 204 0.126
reactive oxygen species metabolic process GO:0072593 75 0.116
purine nucleoside monophosphate catabolic process GO:0009128 158 0.114
regulation of membrane potential GO:0042391 95 0.104
Mouse
cellular ketone metabolic process GO:0042180 80 0.103
energy derivation by oxidation of organic compounds GO:0015980 43 0.099
Mouse
fatty acid metabolic process GO:0006631 115 0.096
Rat
mitochondrial membrane organization GO:0007006 40 0.095
electron transport chain GO:0022900 8 0.090
Mouse
transmembrane transport GO:0055085 399 0.090
defense response GO:0006952 315 0.088
organophosphate biosynthetic process GO:0090407 163 0.085
anion transport GO:0006820 161 0.076
lipid modification GO:0030258 84 0.073
gtp metabolic process GO:0046039 239 0.069
cofactor metabolic process GO:0051186 87 0.067
Rat
positive regulation of hydrolase activity GO:0051345 331 0.067
nucleoside phosphate catabolic process GO:1901292 412 0.066
regulation of cellular ketone metabolic process GO:0010565 50 0.065
nucleoside monophosphate catabolic process GO:0009125 159 0.061
sulfur compound metabolic process GO:0006790 101 0.060
Rat
protein localization to organelle GO:0033365 280 0.058
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.057
vesicle mediated transport GO:0016192 371 0.055
Worm
response to other organism GO:0051707 261 0.055
response to oxidative stress GO:0006979 121 0.054
cellular lipid metabolic process GO:0044255 303 0.054
Rat
acyl coa biosynthetic process GO:0071616 6 0.054
Rat
protein processing GO:0016485 226 0.053
cation transmembrane transport GO:0098655 238 0.052
organic acid transport GO:0015849 65 0.052
female gamete generation GO:0007292 2 0.051
regeneration GO:0031099 4 0.050
embryo development GO:0009790 123 0.050
Mouse Worm
positive regulation of peptidase activity GO:0010952 88 0.048
regulation of peptidase activity GO:0052547 180 0.044
single organism membrane organization GO:0044802 268 0.042
organic hydroxy compound biosynthetic process GO:1901617 71 0.042
nervous system development GO:0007399 293 0.042
organic hydroxy compound metabolic process GO:1901615 147 0.042
purine nucleotide biosynthetic process GO:0006164 84 0.041
regulation of proteolysis GO:0030162 293 0.040
embryo development ending in birth or egg hatching GO:0009792 34 0.040
Worm
alcohol metabolic process GO:0006066 114 0.040
secretion by cell GO:0032940 226 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
inorganic ion transmembrane transport GO:0098660 231 0.038
guanosine containing compound metabolic process GO:1901068 244 0.038
lipid catabolic process GO:0016042 84 0.037
acetyl coa biosynthetic process GO:0006085 6 0.037
Rat
cellular amino acid metabolic process GO:0006520 116 0.037
protein maturation GO:0051604 233 0.036
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.035
tricarboxylic acid cycle GO:0006099 4 0.035
intracellular protein transport GO:0006886 270 0.034
small molecule catabolic process GO:0044282 92 0.034
positive regulation of apoptotic process GO:0043065 246 0.033
nucleotide biosynthetic process GO:0009165 109 0.033
monocarboxylic acid catabolic process GO:0072329 37 0.033
single organism carbohydrate metabolic process GO:0044723 193 0.033
isocitrate metabolic process GO:0006102 1 0.033
lipid biosynthetic process GO:0008610 177 0.033
carbohydrate metabolic process GO:0005975 207 0.033
thioester metabolic process GO:0035383 23 0.031
Rat
cellular amine metabolic process GO:0044106 41 0.031
amine metabolic process GO:0009308 44 0.030
regulation of response to external stimulus GO:0032101 222 0.030
purine containing compound biosynthetic process GO:0072522 88 0.030
membrane fusion GO:0061025 43 0.030
regulation of cysteine type endopeptidase activity GO:2000116 127 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.029
tricarboxylic acid metabolic process GO:0072350 4 0.029
neural nucleus development GO:0048857 47 0.029
acetyl coa biosynthetic process from pyruvate GO:0006086 4 0.029
Rat
membrane organization GO:0061024 292 0.029
Worm
small molecule biosynthetic process GO:0044283 157 0.029
nucleoside triphosphate biosynthetic process GO:0009142 20 0.029
response to biotic stimulus GO:0009607 276 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
wound healing GO:0042060 115 0.028
system process GO:0003008 349 0.027
response to steroid hormone GO:0048545 80 0.027
response to virus GO:0009615 126 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
fatty acid catabolic process GO:0009062 29 0.026
glycosyl compound biosynthetic process GO:1901659 27 0.025
response to hormone GO:0009725 175 0.025
protein oligomerization GO:0051259 173 0.025
fatty acid beta oxidation using acyl coa dehydrogenase GO:0033539 3 0.025
innate immune response GO:0045087 178 0.024
reproduction GO:0000003 63 0.024
Mouse Worm
organic acid catabolic process GO:0016054 71 0.024
protein homooligomerization GO:0051260 100 0.024
oogenesis GO:0048477 2 0.024
organic acid biosynthetic process GO:0016053 97 0.023
response to lipid GO:0033993 206 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
regulation of mitochondrial membrane potential GO:0051881 23 0.023
response to extracellular stimulus GO:0009991 85 0.022
spermatid differentiation GO:0048515 4 0.022
Mouse
positive regulation of proteolysis GO:0045862 142 0.022
lipid localization GO:0010876 106 0.022
guanosine containing compound catabolic process GO:1901069 239 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
single organism cellular localization GO:1902580 332 0.021
mitochondrial transport GO:0006839 60 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of transferase activity GO:0051338 355 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
negative regulation of transferase activity GO:0051348 124 0.020
cell projection organization GO:0030030 252 0.019
cytoplasmic transport GO:0016482 379 0.019
response to wounding GO:0009611 168 0.019
cellular component disassembly GO:0022411 92 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
positive regulation of catabolic process GO:0009896 310 0.018
ribonucleotide biosynthetic process GO:0009260 81 0.018
cellular protein catabolic process GO:0044257 261 0.018
receptor mediated endocytosis GO:0006898 84 0.017
regulation of cytokine production GO:0001817 232 0.017
response to oxygen containing compound GO:1901700 369 0.017
positive regulation of transport GO:0051050 336 0.017
response to abiotic stimulus GO:0009628 336 0.017
carboxylic acid catabolic process GO:0046395 71 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
lipid transport GO:0006869 90 0.016
defense response to other organism GO:0098542 129 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
multicellular organismal homeostasis GO:0048871 67 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
brain development GO:0007420 97 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
response to bacterium GO:0009617 144 0.015
ossification GO:0001503 121 0.015
cation transport GO:0006812 331 0.015
protein acylation GO:0043543 138 0.015
tissue homeostasis GO:0001894 63 0.015
zymogen activation GO:0031638 70 0.015
cellular response to oxidative stress GO:0034599 85 0.014
response to nutrient levels GO:0031667 81 0.014
protein localization to mitochondrion GO:0070585 25 0.014
sleep GO:0030431 2 0.014
substantia nigra development GO:0021762 45 0.014
microtubule based process GO:0007017 210 0.014
ion transmembrane transport GO:0034220 338 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
protein modification by small protein removal GO:0070646 92 0.013
maintenance of location GO:0051235 112 0.013
response to starvation GO:0042594 59 0.013
central nervous system development GO:0007417 123 0.012
midbrain development GO:0030901 45 0.012
chromatin modification GO:0016568 298 0.012
aging GO:0007568 66 0.012
Rat Worm
neuromuscular junction development GO:0007528 3 0.012
cellular protein complex assembly GO:0043623 188 0.012
epithelium development GO:0060429 227 0.012
endosomal transport GO:0016197 129 0.012
immune response GO:0006955 307 0.012
cell morphogenesis GO:0000902 296 0.012
tissue regeneration GO:0042246 3 0.012
regulation of protein maturation GO:1903317 150 0.012
nitrogen compound transport GO:0071705 191 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
organic anion transport GO:0015711 103 0.011
spermatid development GO:0007286 4 0.011
Mouse
positive regulation of cell death GO:0010942 263 0.011
metal ion transport GO:0030001 272 0.011
response to reactive oxygen species GO:0000302 61 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
cellular chemical homeostasis GO:0055082 180 0.011
anatomical structure homeostasis GO:0060249 100 0.011
actin mediated cell contraction GO:0070252 12 0.011
cytokine production GO:0001816 247 0.011
single organism membrane fusion GO:0044801 37 0.011
regulation of kinase activity GO:0043549 314 0.011
regulation of cellular amino acid metabolic process GO:0006521 6 0.011
covalent chromatin modification GO:0016569 254 0.011
response to endoplasmic reticulum stress GO:0034976 49 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
lipid storage GO:0019915 28 0.011
release of cytochrome c from mitochondria GO:0001836 35 0.011
angiogenesis GO:0001525 147 0.011
activation of cysteine type endopeptidase activity GO:0097202 57 0.011
developmental process involved in reproduction GO:0003006 66 0.011
Mouse
negative regulation of phosphorylation GO:0042326 174 0.010
ribose phosphate biosynthetic process GO:0046390 82 0.010
cellular component morphogenesis GO:0032989 314 0.010
positive regulation of endopeptidase activity GO:0010950 84 0.010
alcohol biosynthetic process GO:0046165 52 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
nucleoside biosynthetic process GO:0009163 26 0.010
negative regulation of organelle organization GO:0010639 126 0.010
glycogen metabolic process GO:0005977 22 0.010

DLD disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.169
amino acid metabolic disorder DOID:9252 50 0.162
inherited metabolic disorder DOID:655 242 0.162
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
musculoskeletal system disease DOID:17 223 0.013
epilepsy syndrome DOID:1826 41 0.012
idiopathic generalized epilepsy DOID:1827 21 0.012
brain disease DOID:936 73 0.012
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
organ system cancer DOID:0050686 164 0.011
organic acidemia DOID:0060159 14 0.011
sensory system disease DOID:0050155 203 0.010
maple syrup urine disease DOID:9269 5 0.000