Homo sapiens

261 known processes

CIB1

calcium and integrin binding 1 (calmyrin)

(Aliases: CIB,KIP,KIP1,SIP2-28)

CIB1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lung alveolus development GO:0048286 4 0.252
brain morphogenesis GO:0048854 1 0.236
regulation of cellular amine metabolic process GO:0033238 11 0.222
amine metabolic process GO:0009308 44 0.191
cardiac muscle contraction GO:0060048 34 0.188
actin mediated cell contraction GO:0070252 12 0.187
positive regulation of transport GO:0051050 336 0.164
striated muscle contraction GO:0006941 52 0.163
negative regulation of proteolysis GO:0045861 132 0.145
epidermis development GO:0008544 59 0.145
segmentation GO:0035282 4 0.144
regulation of cellular amino acid metabolic process GO:0006521 6 0.142
somitogenesis GO:0001756 2 0.137
negative regulation of ligase activity GO:0051352 8 0.136
cellular amine metabolic process GO:0044106 41 0.130
negative regulation of protein maturation GO:1903318 142 0.123
regulation of synaptic plasticity GO:0048167 3 0.112
positive regulation of immune system process GO:0002684 283 0.106
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.100
epithelial cell differentiation GO:0030855 141 0.098
regulation of transferase activity GO:0051338 355 0.094
Mouse
myeloid cell differentiation GO:0030099 117 0.094
Mouse
cellular ketone metabolic process GO:0042180 80 0.092
negative regulation of cell death GO:0060548 345 0.088
regulation of cellular ketone metabolic process GO:0010565 50 0.087
negative regulation of protein metabolic process GO:0051248 391 0.086
Mouse
negative regulation of cellular component organization GO:0051129 235 0.085
heart contraction GO:0060047 62 0.084
regulation of establishment of protein localization GO:0070201 242 0.083
muscle contraction GO:0006936 73 0.081
actin filament based movement GO:0030048 17 0.078
regulation of kinase activity GO:0043549 314 0.078
Mouse
muscle system process GO:0003012 81 0.077
single organism cellular localization GO:1902580 332 0.077
negative regulation of catalytic activity GO:0043086 335 0.076
inorganic cation transmembrane transport GO:0098662 194 0.076
skin development GO:0043588 76 0.075
apoptotic signaling pathway GO:0097190 268 0.074
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.070
positive regulation of coagulation GO:0050820 11 0.069
regulation of protein localization GO:0032880 296 0.068
negative regulation of cellular amine metabolic process GO:0033239 3 0.068
negative regulation of cellular protein metabolic process GO:0032269 353 0.066
Mouse
regulation of immune response GO:0050776 201 0.064
neural tube patterning GO:0021532 2 0.061
thymus development GO:0048538 3 0.061
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.061
negative regulation of protein processing GO:0010955 142 0.060
immune response GO:0006955 307 0.060
regulation of protein kinase activity GO:0045859 289 0.059
Mouse
ion transmembrane transport GO:0034220 338 0.058
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.057
epithelium development GO:0060429 227 0.056
protein maturation GO:0051604 233 0.056
cellular response to oxygen containing compound GO:1901701 276 0.055
ubiquitin dependent protein catabolic process GO:0006511 206 0.055
regulation of protein processing GO:0070613 150 0.055
immune response regulating signaling pathway GO:0002764 97 0.054
memory GO:0007613 3 0.053
heart process GO:0003015 62 0.053
lymphocyte activation GO:0046649 133 0.053
cellular divalent inorganic cation homeostasis GO:0072503 128 0.052
chemical homeostasis GO:0048878 306 0.050
cellular component morphogenesis GO:0032989 314 0.050
regulation of intracellular transport GO:0032386 195 0.050
metal ion homeostasis GO:0055065 169 0.050
hair follicle maturation GO:0048820 3 0.049
hair cycle GO:0042633 28 0.047
negative regulation of phosphorus metabolic process GO:0010563 267 0.046
Mouse
protein processing GO:0016485 226 0.046
regulation of cellular component biogenesis GO:0044087 281 0.045
neuromuscular junction development GO:0007528 3 0.045
cellular amino acid metabolic process GO:0006520 116 0.045
mitotic cell cycle process GO:1903047 286 0.044
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.044
cellular macromolecular complex assembly GO:0034622 324 0.043
plasma membrane organization GO:0007009 115 0.042
negative regulation of protein catabolic process GO:0042177 59 0.042
cation homeostasis GO:0055080 189 0.042
enzyme linked receptor protein signaling pathway GO:0007167 303 0.042
motor neuron axon guidance GO:0008045 2 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.041
negative regulation of protein modification process GO:0031400 200 0.041
Mouse
divalent metal ion transport GO:0070838 152 0.041
blood circulation GO:0008015 113 0.041
regulation of protein maturation GO:1903317 150 0.040
intracellular protein transport GO:0006886 270 0.040
cellular protein complex assembly GO:0043623 188 0.040
cytoplasmic transport GO:0016482 379 0.040
cellular metal ion homeostasis GO:0006875 146 0.040
divalent inorganic cation transport GO:0072511 158 0.039
extrinsic apoptotic signaling pathway GO:0097191 119 0.039
coagulation GO:0050817 78 0.039
circulatory system process GO:0003013 113 0.038
inorganic ion transmembrane transport GO:0098660 231 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.036
Mouse
negative regulation of protein phosphorylation GO:0001933 140 0.036
Mouse
determination of adult lifespan GO:0008340 2 0.036
negative regulation of binding GO:0051100 57 0.036
immune effector process GO:0002252 159 0.035
negative regulation of cellular catabolic process GO:0031330 83 0.035
cell activation GO:0001775 213 0.034
positive regulation of intracellular transport GO:0032388 104 0.034
negative regulation of apoptotic signaling pathway GO:2001234 97 0.034
receptor metabolic process GO:0043112 81 0.033
vesicle mediated transport GO:0016192 371 0.033
cilium organization GO:0044782 68 0.033
hemopoiesis GO:0030097 180 0.033
Mouse
leukocyte activation GO:0045321 164 0.032
biological adhesion GO:0022610 331 0.032
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.032
cellular homeostasis GO:0019725 196 0.032
cellular cation homeostasis GO:0030003 163 0.032
cell projection assembly GO:0030031 126 0.032
positive regulation of organelle organization GO:0010638 195 0.031
secretion by cell GO:0032940 226 0.031
calcium ion transmembrane transport GO:0070588 76 0.031
regulation of apoptotic signaling pathway GO:2001233 175 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.030
positive regulation of phosphorylation GO:0042327 394 0.030
Mouse
cardiac muscle cell contraction GO:0086003 4 0.030
positive regulation of protein transport GO:0051222 135 0.030
protein localization to organelle GO:0033365 280 0.030
microtubule based process GO:0007017 210 0.029
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.029
membrane organization GO:0061024 292 0.029
lipid metabolic process GO:0006629 381 0.029
regulation of protein transport GO:0051223 213 0.029
negative regulation of multicellular organismal process GO:0051241 317 0.028
negative regulation of catabolic process GO:0009895 104 0.028
protein localization to membrane GO:0072657 160 0.028
ion homeostasis GO:0050801 230 0.028
nuclear transport GO:0051169 179 0.027
carbohydrate metabolic process GO:0005975 207 0.027
cilium assembly GO:0042384 63 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
calcium ion transport GO:0006816 147 0.027
hair cycle phase GO:0044851 3 0.027
cellular chemical homeostasis GO:0055082 180 0.026
cell competition in a multicellular organism GO:0035212 1 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
cation transmembrane transport GO:0098655 238 0.026
positive regulation of secretion GO:0051047 116 0.026
positive regulation of cytoskeleton organization GO:0051495 83 0.026
cellular lipid metabolic process GO:0044255 303 0.026
metal ion transport GO:0030001 272 0.026
post embryonic development GO:0009791 2 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
Mouse
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.025
protein ubiquitination GO:0016567 314 0.025
response to external biotic stimulus GO:0043207 261 0.025
purine containing compound catabolic process GO:0072523 411 0.025
regulation of proteolysis GO:0030162 293 0.024
regulation of binding GO:0051098 111 0.024
single organism cell adhesion GO:0098602 179 0.024
neurological system process GO:0050877 163 0.024
positive regulation of immune response GO:0050778 159 0.024
establishment of protein localization to organelle GO:0072594 172 0.024
immune system development GO:0002520 195 0.024
Mouse
regulation of coagulation GO:0050818 44 0.024
cellular ion homeostasis GO:0006873 168 0.024
calcium ion homeostasis GO:0055074 122 0.023
melanocyte differentiation GO:0030318 2 0.023
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
negative regulation of protein ubiquitination GO:0031397 35 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.023
Mouse
protein targeting GO:0006605 187 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
cell adhesion GO:0007155 325 0.023
sequestering of metal ion GO:0051238 24 0.023
regulation of secretion GO:0051046 194 0.023
cation transport GO:0006812 331 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.022
negative regulation of transferase activity GO:0051348 124 0.022
membrane protein proteolysis GO:0033619 38 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
hair follicle development GO:0001942 11 0.022
membrane protein ectodomain proteolysis GO:0006509 33 0.022
regulation of protein complex assembly GO:0043254 147 0.022
cellular calcium ion homeostasis GO:0006874 117 0.022
peptidyl tyrosine modification GO:0018212 170 0.022
t cell activation GO:0042110 99 0.021
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.021
syncytium formation by plasma membrane fusion GO:0000768 2 0.021
cellular amide metabolic process GO:0043603 69 0.021
organ morphogenesis GO:0009887 147 0.021
immune response activating signal transduction GO:0002757 90 0.021
regulation of proteasomal protein catabolic process GO:0061136 87 0.021
cell projection organization GO:0030030 252 0.021
sequestering of calcium ion GO:0051208 17 0.021
embryonic morphogenesis GO:0048598 85 0.020
activation of immune response GO:0002253 114 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
myeloid leukocyte differentiation GO:0002573 60 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
single organismal cell cell adhesion GO:0016337 148 0.020
hair cycle process GO:0022405 12 0.020
transmembrane transport GO:0055085 399 0.020
negative regulation of kinase activity GO:0033673 106 0.020
myoblast fusion GO:0007520 1 0.020
endomembrane system organization GO:0010256 196 0.020
vesicle organization GO:0016050 62 0.020
cilium morphogenesis GO:0060271 75 0.020
regulation of secretion by cell GO:1903530 177 0.019
head development GO:0060322 108 0.019
negative regulation of protein kinase activity GO:0006469 98 0.019
peptide metabolic process GO:0006518 51 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
negative regulation of cellular protein catabolic process GO:1903363 38 0.019
protein localization to plasma membrane GO:0072659 93 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
fatty acid metabolic process GO:0006631 115 0.018
lipid biosynthetic process GO:0008610 177 0.018
neurogenesis GO:0022008 169 0.018
cellular protein catabolic process GO:0044257 261 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
dorsal ventral pattern formation GO:0009953 15 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
mitotic cell cycle GO:0000278 326 0.018
maintenance of location GO:0051235 112 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
behavioral response to ethanol GO:0048149 2 0.017
organelle fission GO:0048285 149 0.017
nucleotide catabolic process GO:0009166 408 0.017
regulation of protein catabolic process GO:0042176 155 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
Mouse
system process GO:0003008 349 0.017
cell morphogenesis GO:0000902 296 0.017
cell growth GO:0016049 160 0.017
Mouse
single organism membrane organization GO:0044802 268 0.017
small molecule biosynthetic process GO:0044283 157 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
regulation of receptor activity GO:0010469 47 0.017
nucleoside catabolic process GO:0009164 408 0.017
central nervous system development GO:0007417 123 0.017
respiratory tube development GO:0030323 20 0.016
dephosphorylation GO:0016311 209 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
interspecies interaction between organisms GO:0044419 156 0.016
nervous system development GO:0007399 293 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
leukocyte differentiation GO:0002521 98 0.016
actin filament based process GO:0030029 224 0.016
multicellular organismal aging GO:0010259 3 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
regulation of protein binding GO:0043393 66 0.016
regulation of protein targeting GO:1903533 91 0.016
regulation of cell projection assembly GO:0060491 47 0.015
nuclear import GO:0051170 106 0.015
molting cycle GO:0042303 28 0.015
positive regulation of arp2 3 complex mediated actin nucleation GO:2000601 5 0.015
leukocyte activation involved in immune response GO:0002366 30 0.015
cell part morphogenesis GO:0032990 137 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
rna interference GO:0016246 4 0.015
regulation of cell cycle process GO:0010564 266 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
regulation of cell cycle GO:0051726 393 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
ribonucleotide catabolic process GO:0009261 405 0.014
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.014
negative regulation of protein complex assembly GO:0031333 43 0.014
regulation of ubiquitin protein transferase activity GO:0051438 28 0.014
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.014
embryo development GO:0009790 123 0.014
cell type specific apoptotic process GO:0097285 125 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
regulation of ion transport GO:0043269 189 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.014
protein catabolic process GO:0030163 325 0.014
hematopoietic progenitor cell differentiation GO:0002244 38 0.014
Mouse
regionalization GO:0003002 29 0.014
brain development GO:0007420 97 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
multi organism cellular process GO:0044764 156 0.013
response to bacterium GO:0009617 144 0.013
organophosphate catabolic process GO:0046434 430 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
cell development GO:0048468 328 0.013
establishment of protein localization to plasma membrane GO:0090002 68 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.013
myosin filament organization GO:0031033 2 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.013
cuticle development GO:0042335 1 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
negative regulation of cell cycle GO:0045786 193 0.013
protein targeting to nucleus GO:0044744 104 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 70 0.013
positive regulation of cell death GO:0010942 263 0.013
regulation of hormone levels GO:0010817 125 0.012
response to other organism GO:0051707 261 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
regeneration GO:0031099 4 0.012
regulation of transmembrane transporter activity GO:0022898 74 0.012
vesicle transport along actin filament GO:0030050 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
response to biotic stimulus GO:0009607 276 0.012
sensory perception of pain GO:0019233 4 0.012
dna repair GO:0006281 198 0.012
regulation of protein localization to plasma membrane GO:1903076 40 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
positive regulation of transferase activity GO:0051347 227 0.012
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.012
positive regulation of cytoplasmic transport GO:1903651 82 0.012
pattern specification process GO:0007389 43 0.012
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
regulation of cell growth GO:0001558 135 0.012
Mouse
pigmentation GO:0043473 22 0.012
transcription factor import into nucleus GO:0042991 40 0.012
behavior GO:0007610 112 0.012
response to inorganic substance GO:0010035 127 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of erbb signaling pathway GO:1901184 27 0.012
regulation of growth GO:0040008 165 0.012
Mouse
oocyte differentiation GO:0009994 2 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
protein import into nucleus GO:0006606 104 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
hemostasis GO:0007599 76 0.011
regulation of receptor recycling GO:0001919 10 0.011
organelle assembly GO:0070925 176 0.011
single organism nuclear import GO:1902593 104 0.011
protein localization to nucleus GO:0034504 136 0.011
antigen receptor mediated signaling pathway GO:0050851 38 0.011
associative learning GO:0008306 1 0.011
negative regulation of protein binding GO:0032091 35 0.011
negative regulation of receptor activity GO:2000272 15 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
molting cycle process GO:0022404 12 0.011
regulation of response to external stimulus GO:0032101 222 0.011
lung development GO:0030324 20 0.011
organic acid biosynthetic process GO:0016053 97 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
Mouse
oogenesis GO:0048477 2 0.011
viral life cycle GO:0019058 132 0.011
erbb signaling pathway GO:0038127 44 0.011
response to radiation GO:0009314 151 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
response to abiotic stimulus GO:0009628 336 0.010
regulation of cellular response to stress GO:0080135 244 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
golgi vesicle transport GO:0048193 80 0.010
cellular lipid catabolic process GO:0044242 65 0.010
rhythmic behavior GO:0007622 2 0.010

CIB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
dementia DOID:1307 19 0.150
alzheimer s disease DOID:10652 16 0.150
central nervous system disease DOID:331 186 0.150
disease of mental health DOID:150 70 0.150
tauopathy DOID:680 16 0.150
neurodegenerative disease DOID:1289 102 0.150
nervous system disease DOID:863 431 0.150
cognitive disorder DOID:1561 29 0.150
cardiovascular system disease DOID:1287 106 0.103
myopathy DOID:423 104 0.080
muscular disease DOID:0080000 114 0.080
heart disease DOID:114 68 0.080
cardiomyopathy DOID:0050700 50 0.080
musculoskeletal system disease DOID:17 223 0.080
muscle tissue disease DOID:66 113 0.080
dilated cardiomyopathy DOID:12930 32 0.058
intrinsic cardiomyopathy DOID:0060036 50 0.058
disease of metabolism DOID:0014667 295 0.019
inherited metabolic disorder DOID:655 242 0.019
connective tissue disease DOID:65 109 0.018
bone development disease DOID:0080006 55 0.013
bone disease DOID:0080001 88 0.013
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
sensory system disease DOID:0050155 203 0.012
amino acid metabolic disorder DOID:9252 50 0.012
organ system cancer DOID:0050686 164 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
osteochondrodysplasia DOID:2256 35 0.011