Homo sapiens

0 known processes

TRIO

triple functional domain (PTPRF interacting)

(Aliases: tgat,ARHGEF23,FLJ42780)

TRIO biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of locomotion GO:0040012 329 0.771
Worm
directional locomotion GO:0033058 1 0.735
taxis GO:0042330 157 0.593
Worm Fly
mating GO:0007618 1 0.589
regulation of cell differentiation GO:0045595 393 0.566
Worm Fly
regulation of cell development GO:0060284 161 0.514
Worm Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.513
Worm Fly
cell development GO:0048468 328 0.502
Worm Fly
chemotaxis GO:0006935 157 0.480
Worm Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.476
Worm Fly
regulation of cell migration GO:0030334 289 0.461
positive regulation of cellular component organization GO:0051130 376 0.415
Worm Fly
regulation of cell motility GO:2000145 299 0.412
nervous system development GO:0007399 293 0.402
Worm Fly
cellular component morphogenesis GO:0032989 314 0.394
Worm Fly
cell morphogenesis GO:0000902 296 0.381
Worm Fly
cellular amine metabolic process GO:0044106 41 0.378
positive regulation of cell development GO:0010720 92 0.374
Worm
positive regulation of developmental process GO:0051094 314 0.350
Worm Fly
small gtpase mediated signal transduction GO:0007264 78 0.333
Fly
regulation of cellular component movement GO:0051270 334 0.330
regulation of neurogenesis GO:0050767 82 0.328
Worm Fly
ameboidal type cell migration GO:0001667 135 0.311
regulation of neuron differentiation GO:0045664 70 0.309
Worm Fly
regulation of cell projection organization GO:0031344 107 0.301
Worm Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.287
Worm Fly
cellular amino acid metabolic process GO:0006520 116 0.274
regulation of nervous system development GO:0051960 88 0.274
Worm Fly
regulation of extent of cell growth GO:0061387 9 0.261
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.258
nucleoside catabolic process GO:0009164 408 0.258
Worm Fly
neuron differentiation GO:0030182 138 0.254
Worm Fly
neurogenesis GO:0022008 169 0.251
Worm Fly
regulation of cellular amine metabolic process GO:0033238 11 0.249
nucleoside phosphate catabolic process GO:1901292 412 0.248
Worm Fly
vesicle mediated transport GO:0016192 371 0.246
Worm
positive regulation of nervous system development GO:0051962 54 0.245
Worm Fly
cell cell signaling GO:0007267 155 0.241
Fly
positive regulation of locomotion GO:0040017 186 0.240
regulation of neuron projection development GO:0010975 57 0.232
Worm Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.221
Worm
growth GO:0040007 202 0.218
Worm Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.217
Worm Fly
positive regulation of cellular component movement GO:0051272 181 0.214
axon extension GO:0048675 13 0.213
Worm Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.204
developmental growth involved in morphogenesis GO:0060560 23 0.203
Worm Fly
positive regulation of cell migration GO:0030335 172 0.202
positive regulation of cell projection organization GO:0031346 64 0.201
Worm
positive regulation of neurogenesis GO:0050769 49 0.200
Worm
regulation of cell growth GO:0001558 135 0.198
Worm
ras protein signal transduction GO:0007265 73 0.198
Fly
regulation of growth GO:0040008 165 0.197
Worm Fly
cellular ketone metabolic process GO:0042180 80 0.194
regulation of cell morphogenesis GO:0022604 153 0.188
Worm Fly
positive regulation of cell motility GO:2000147 177 0.186
developmental cell growth GO:0048588 18 0.184
Worm Fly
generation of neurons GO:0048699 152 0.183
Worm Fly
neuron projection morphogenesis GO:0048812 50 0.180
Worm Fly
cell growth GO:0016049 160 0.174
Worm Fly
actin cytoskeleton organization GO:0030036 207 0.174
Worm Fly
nucleotide catabolic process GO:0009166 408 0.166
Worm Fly
post embryonic development GO:0009791 2 0.164
Fly
regulation of cellular component biogenesis GO:0044087 281 0.159
Worm Fly
positive regulation of hydrolase activity GO:0051345 331 0.154
Worm Fly
neuron development GO:0048666 113 0.154
Worm Fly
purine ribonucleotide catabolic process GO:0009154 404 0.149
Worm Fly
amine metabolic process GO:0009308 44 0.149
regulation of axonogenesis GO:0050770 16 0.147
Worm Fly
female gamete generation GO:0007292 2 0.146
gtp catabolic process GO:0006184 237 0.144
Worm Fly
glycosyl compound catabolic process GO:1901658 413 0.139
Worm Fly
ribonucleotide catabolic process GO:0009261 405 0.139
Worm Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.138
Worm Fly
positive regulation of neuron projection development GO:0010976 34 0.138
Worm
positive regulation of cell growth GO:0030307 48 0.135
Worm
positive regulation of neuron differentiation GO:0045666 40 0.134
Worm
actin filament based process GO:0030029 224 0.134
Worm Fly
cell adhesion GO:0007155 325 0.131
regulation of gtp catabolic process GO:0033124 180 0.129
Worm Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.127
Worm Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.126
Worm Fly
motor neuron axon guidance GO:0008045 2 0.121
regulation of nucleoside metabolic process GO:0009118 209 0.121
Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.121
Worm Fly
positive regulation of cell differentiation GO:0045597 211 0.119
Worm
rho protein signal transduction GO:0007266 26 0.119
Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 0.119
Worm Fly
biological adhesion GO:0022610 331 0.116
neuron projection development GO:0031175 106 0.116
Worm Fly
positive regulation of axonogenesis GO:0050772 9 0.113
Worm
multicellular organismal aging GO:0010259 3 0.113
positive regulation of cellular amine metabolic process GO:0033240 7 0.111
axonogenesis GO:0007409 31 0.110
Worm Fly
regulation of anatomical structure size GO:0090066 101 0.106
Worm
cell projection organization GO:0030030 252 0.104
Worm Fly
positive regulation of phosphorylation GO:0042327 394 0.104
purine containing compound catabolic process GO:0072523 411 0.096
Worm Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.096
Worm Fly
response to oxygen containing compound GO:1901700 369 0.095
behavior GO:0007610 112 0.095
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.093
Worm Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.091
Worm Fly
system process GO:0003008 349 0.091
ribonucleoside triphosphate catabolic process GO:0009203 391 0.090
Worm Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.089
Worm Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089
muscle structure development GO:0061061 98 0.089
ribonucleoside catabolic process GO:0042454 406 0.088
Worm Fly
positive regulation of growth GO:0045927 58 0.087
Worm Fly
negative regulation of multicellular organismal process GO:0051241 317 0.085
determination of adult lifespan GO:0008340 2 0.084
negative regulation of cell migration GO:0030336 102 0.080
muscle organ development GO:0007517 56 0.080
positive regulation of nucleoside metabolic process GO:0045979 186 0.078
Worm Fly
negative regulation of developmental process GO:0051093 247 0.078
locomotory behavior GO:0007626 1 0.076
positive regulation of catabolic process GO:0009896 310 0.076
Worm Fly
positive regulation of axon extension GO:0045773 4 0.076
Worm
guanosine containing compound catabolic process GO:1901069 239 0.075
Worm Fly
regulation of cytoskeleton organization GO:0051493 177 0.075
Worm
negative regulation of cellular component movement GO:0051271 106 0.074
response to growth factor GO:0070848 205 0.073
Fly
developmental growth GO:0048589 48 0.073
Worm Fly
gtp metabolic process GO:0046039 239 0.072
Worm Fly
reproductive process GO:0022414 106 0.071
Worm
positive regulation of cellular catabolic process GO:0031331 284 0.071
Worm Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.069
ribonucleoside triphosphate metabolic process GO:0009199 412 0.069
Worm Fly
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.069
regulation of nucleotide catabolic process GO:0030811 205 0.067
Worm Fly
oogenesis GO:0048477 2 0.067
anatomical structure formation involved in morphogenesis GO:0048646 284 0.066
purine nucleotide catabolic process GO:0006195 405 0.066
Worm Fly
purine nucleoside catabolic process GO:0006152 398 0.066
Worm Fly
regulation of mapk cascade GO:0043408 262 0.065
cytoplasmic transport GO:0016482 379 0.063
mapk cascade GO:0000165 288 0.062
microtubule cytoskeleton organization GO:0000226 176 0.062
cell projection morphogenesis GO:0048858 129 0.060
Worm Fly
positive regulation of protein phosphorylation GO:0001934 313 0.060
regulation of protein kinase activity GO:0045859 289 0.060
neuromuscular junction development GO:0007528 3 0.060
Fly
post embryonic organ development GO:0048569 1 0.059
Fly
membrane organization GO:0061024 292 0.058
Worm
positive regulation of nucleotide metabolic process GO:0045981 230 0.058
Worm Fly
cellular response to oxygen containing compound GO:1901701 276 0.058
cell part morphogenesis GO:0032990 137 0.058
Worm Fly
cell projection assembly GO:0030031 126 0.057
organophosphate catabolic process GO:0046434 430 0.057
Worm Fly
hindbrain development GO:0030902 3 0.056
negative regulation of apoptotic process GO:0043066 316 0.056
mitotic cell cycle process GO:1903047 286 0.056
axon development GO:0061564 34 0.055
Worm Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.055
Worm Fly
regulation of rho protein signal transduction GO:0035023 79 0.055
Worm Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.055
negative regulation of cell motility GO:2000146 104 0.054
skeletal muscle organ development GO:0060538 26 0.054
regulation of protein localization GO:0032880 296 0.054
regulation of axon guidance GO:1902667 3 0.054
cellular macromolecule catabolic process GO:0044265 380 0.053
actin filament organization GO:0007015 128 0.052
Worm
intracellular protein transport GO:0006886 270 0.052
hematopoietic or lymphoid organ development GO:0048534 186 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.052
positive regulation of transport GO:0051050 336 0.052
response to wounding GO:0009611 168 0.051
epithelium development GO:0060429 227 0.051
single organism cell adhesion GO:0098602 179 0.051
signal transduction by phosphorylation GO:0023014 297 0.051
protein localization to membrane GO:0072657 160 0.051
negative regulation of protein metabolic process GO:0051248 391 0.051
microtubule based process GO:0007017 210 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.050
Worm Fly
response to transforming growth factor beta GO:0071559 94 0.050
regulation of gtpase activity GO:0043087 180 0.049
Worm Fly
organ morphogenesis GO:0009887 147 0.049
Worm Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
Worm Fly
regulation of kinase activity GO:0043549 314 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.048
Worm Fly
segmentation GO:0035282 4 0.047
endomembrane system organization GO:0010256 196 0.047
nerve development GO:0021675 4 0.047
regulation of protein serine threonine kinase activity GO:0071900 179 0.046
axon guidance GO:0007411 12 0.046
Worm Fly
cellular ion homeostasis GO:0006873 168 0.046
cell fate determination GO:0001709 3 0.045
regulation of ras protein signal transduction GO:0046578 155 0.045
Worm Fly
immune response GO:0006955 307 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
Worm Fly
positive regulation of gtp catabolic process GO:0033126 166 0.044
Worm Fly
protein catabolic process GO:0030163 325 0.043
Worm
metal ion transport GO:0030001 272 0.043
positive regulation of gtpase activity GO:0043547 166 0.043
Worm Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
negative regulation of locomotion GO:0040013 118 0.043
negative regulation of cell death GO:0060548 345 0.043
positive regulation of ras gtpase activity GO:0032320 117 0.042
Worm Fly
regulation of transferase activity GO:0051338 355 0.042
peptidyl tyrosine phosphorylation GO:0018108 170 0.040
regulation of axon extension GO:0030516 7 0.040
Worm
negative regulation of hydrolase activity GO:0051346 182 0.040
negative regulation of programmed cell death GO:0043069 321 0.039
histone modification GO:0016570 251 0.039
regulation of developmental growth GO:0048638 30 0.039
Worm Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.039
defense response GO:0006952 315 0.039
regulation of rho gtpase activity GO:0032319 66 0.038
Worm Fly
nucleocytoplasmic transport GO:0006913 176 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
negative regulation of cellular component organization GO:0051129 235 0.038
neuroblast proliferation GO:0007405 4 0.038
cellular response to growth factor stimulus GO:0071363 197 0.037
regulation of epithelial cell migration GO:0010632 93 0.037
protein localization to organelle GO:0033365 280 0.036
mitotic cell cycle GO:0000278 326 0.036
tube development GO:0035295 125 0.036
protein localization to plasma membrane GO:0072659 93 0.036
establishment of protein localization to membrane GO:0090150 121 0.035
positive regulation of kinase activity GO:0033674 204 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.035
organelle assembly GO:0070925 176 0.035
neurological system process GO:0050877 163 0.034
regulation of actin cytoskeleton organization GO:0032956 116 0.034
Worm
receptor mediated endocytosis GO:0006898 84 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
Worm
chromatin organization GO:0006325 351 0.033
dephosphorylation GO:0016311 209 0.033
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.033
cell chemotaxis GO:0060326 112 0.033
peptidyl tyrosine modification GO:0018212 170 0.032
cerebral cortex cell migration GO:0021795 3 0.032
regulation of cell cycle GO:0051726 393 0.032
positive regulation of developmental growth GO:0048639 16 0.032
Worm Fly
glial cell migration GO:0008347 4 0.032
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.032
negative regulation of phosphorylation GO:0042326 174 0.032
cellular chemical homeostasis GO:0055082 180 0.032
wnt signaling pathway GO:0016055 156 0.031
negative regulation of organelle organization GO:0010639 126 0.031
regeneration GO:0031099 4 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
blastoderm segmentation GO:0007350 2 0.031
regulation of microtubule cytoskeleton organization GO:0070507 61 0.031
protein targeting GO:0006605 187 0.031
positive regulation of protein kinase activity GO:0045860 190 0.031
single organism membrane organization GO:0044802 268 0.031
single organism cellular localization GO:1902580 332 0.031
chemical homeostasis GO:0048878 306 0.031
protein ubiquitination GO:0016567 314 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
anterior posterior axis specification GO:0009948 2 0.030
neurotransmitter secretion GO:0007269 4 0.030
negative regulation of protein modification process GO:0031400 200 0.030
regulation of microtubule based process GO:0032886 74 0.030
transmembrane transport GO:0055085 399 0.029
regulation of ras gtpase activity GO:0032318 128 0.029
Worm Fly
cell matrix adhesion GO:0007160 85 0.029
negative regulation of cell differentiation GO:0045596 171 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
Worm Fly
negative regulation of transport GO:0051051 176 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
Worm Fly
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
positive regulation of map kinase activity GO:0043406 80 0.029
regulation of wnt signaling pathway GO:0030111 123 0.029
compound eye development GO:0048749 1 0.028
oocyte differentiation GO:0009994 2 0.028
response to abiotic stimulus GO:0009628 336 0.028
single organismal cell cell adhesion GO:0016337 148 0.028
lipid metabolic process GO:0006629 381 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
regulation of cellular response to stress GO:0080135 244 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
regulation of protein transport GO:0051223 213 0.027
associative learning GO:0008306 1 0.027
wound healing GO:0042060 115 0.027
cation transport GO:0006812 331 0.027
multi organism reproductive process GO:0044703 54 0.027
Worm
endothelial cell migration GO:0043542 86 0.026
epithelial cell migration GO:0010631 119 0.026
i kappab kinase nf kappab signaling GO:0007249 166 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
canonical wnt signaling pathway GO:0060070 116 0.026
positive regulation of wnt signaling pathway GO:0030177 54 0.026
regulation of axon extension involved in axon guidance GO:0048841 2 0.026
regulation of secretion GO:0051046 194 0.026
oocyte development GO:0048599 1 0.026
establishment of protein localization to organelle GO:0072594 172 0.025
central nervous system development GO:0007417 123 0.025
Fly
embryo development GO:0009790 123 0.025
Worm
circulatory system development GO:0072359 262 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
memory GO:0007613 3 0.025
regulation of map kinase activity GO:0043405 108 0.025
response to drug GO:0042493 81 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
regulation of cytoplasmic transport GO:1903649 149 0.025
positive regulation of rac gtpase activity GO:0032855 31 0.025
Worm
regulation of multicellular organism growth GO:0040014 8 0.025
Worm
pericardium development GO:0060039 2 0.024
cellular protein catabolic process GO:0044257 261 0.024
chromatin modification GO:0016568 298 0.024
cellular protein complex assembly GO:0043623 188 0.024
Worm
cell substrate adhesion GO:0031589 132 0.024
regulation of ion transport GO:0043269 189 0.024
cellular calcium ion homeostasis GO:0006874 117 0.024
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.024
regulation of protein catabolic process GO:0042176 155 0.024
positive regulation of transferase activity GO:0051347 227 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of proteolysis GO:0030162 293 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
cellular homeostasis GO:0019725 196 0.023
g protein coupled receptor signaling pathway GO:0007186 207 0.023
regulation of cell size GO:0008361 19 0.023
Worm
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.023
organelle fission GO:0048285 149 0.023
skeletal system development GO:0001501 79 0.023
organelle localization GO:0051640 84 0.023
actin filament bundle assembly GO:0051017 54 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
morphogenesis of a polarized epithelium GO:0001738 3 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
neuron projection guidance GO:0097485 12 0.022
Worm Fly
cell activation GO:0001775 213 0.022
response to other organism GO:0051707 261 0.022
nuclear transport GO:0051169 179 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.022
maintenance of location GO:0051235 112 0.022
positive regulation of cytokine production GO:0001819 167 0.022
forebrain generation of neurons GO:0021872 3 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
apoptotic signaling pathway GO:0097190 268 0.022
carbohydrate metabolic process GO:0005975 207 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
negative regulation of cell cycle GO:0045786 193 0.021
response to oxidative stress GO:0006979 121 0.021
head development GO:0060322 108 0.021
Fly
regulation of immune response GO:0050776 201 0.021
positive regulation of immune system process GO:0002684 283 0.021
regulation of protein localization to nucleus GO:1900180 85 0.021
anterior posterior axis specification embryo GO:0008595 2 0.021
regulation of cellular component size GO:0032535 82 0.021
Worm
neuron projection regeneration GO:0031102 1 0.021
regulation of intracellular protein transport GO:0033157 123 0.021
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.021
adult locomotory behavior GO:0008344 1 0.021
protein maturation GO:0051604 233 0.020
cell junction assembly GO:0034329 67 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
myosin filament assembly GO:0031034 2 0.020
regulation of behavior GO:0050795 82 0.020
regulation of actin filament based process GO:0032970 141 0.020
Worm
cellular response to oxidative stress GO:0034599 85 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
multicellular organismal reproductive process GO:0048609 40 0.020
Worm
tripartite regional subdivision GO:0007351 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
establishment of tissue polarity GO:0007164 3 0.020
positive regulation of rho gtpase activity GO:0032321 56 0.020
Worm Fly
positive regulation of mapk cascade GO:0043410 190 0.019
multicellular organism reproduction GO:0032504 42 0.019
Worm
atp catabolic process GO:0006200 157 0.019
protein localization to nucleus GO:0034504 136 0.019
behavioral response to ethanol GO:0048149 2 0.019
reproduction GO:0000003 63 0.019
Worm
reactive oxygen species metabolic process GO:0072593 75 0.019
thymus development GO:0048538 3 0.019
ion homeostasis GO:0050801 230 0.019
regulation of cell cycle process GO:0010564 266 0.019
response to axon injury GO:0048678 1 0.019
negative regulation of epithelial cell migration GO:0010633 38 0.019
plasma membrane organization GO:0007009 115 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.019
limbic system development GO:0021761 3 0.019
spermatid differentiation GO:0048515 4 0.019
regulation of neurotransmitter secretion GO:0046928 3 0.019
rhythmic behavior GO:0007622 2 0.019
metal ion homeostasis GO:0055065 169 0.019
atp metabolic process GO:0046034 176 0.019
forebrain neuron differentiation GO:0021879 3 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
regulation of response to external stimulus GO:0032101 222 0.018
protein oligomerization GO:0051259 173 0.018
ion transmembrane transport GO:0034220 338 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
cellular cation homeostasis GO:0030003 163 0.018
negative regulation of proteolysis GO:0045861 132 0.018
cellular lipid metabolic process GO:0044255 303 0.018
cellular component disassembly GO:0022411 92 0.018
immune system development GO:0002520 195 0.018
cardiovascular system development GO:0072358 262 0.018
establishment of protein localization to plasma membrane GO:0090002 68 0.018
positive regulation of organelle organization GO:0010638 195 0.018
Worm
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
actin filament bundle organization GO:0061572 54 0.018
regulation of dephosphorylation GO:0035303 96 0.018
stem cell development GO:0048864 69 0.018
peripheral nervous system development GO:0007422 2 0.018
Fly
regulation of intracellular transport GO:0032386 195 0.018
positive regulation of intracellular transport GO:0032388 104 0.018
protein autophosphorylation GO:0046777 123 0.018
response to nitrogen compound GO:1901698 184 0.018
secretion by cell GO:0032940 226 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
regulation of chemotaxis GO:0050920 74 0.018
response to lipid GO:0033993 206 0.018
negative regulation of catabolic process GO:0009895 104 0.017
regulation of cell adhesion GO:0030155 166 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
retinal ganglion cell axon guidance GO:0031290 2 0.017
cation transmembrane transport GO:0098655 238 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
brain development GO:0007420 97 0.017
Fly
regulation of protein complex assembly GO:0043254 147 0.017
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
protein processing GO:0016485 226 0.017
secretion GO:0046903 254 0.017
blood vessel morphogenesis GO:0048514 162 0.016
stress fiber assembly GO:0043149 40 0.016
focal adhesion assembly GO:0048041 30 0.016
cilium morphogenesis GO:0060271 75 0.016
actomyosin structure organization GO:0031032 59 0.016
stem cell differentiation GO:0048863 93 0.016
protein import GO:0017038 130 0.016
covalent chromatin modification GO:0016569 254 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
cellular response to reactive oxygen species GO:0034614 50 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
cytokine production GO:0001816 247 0.016
mitochondrion organization GO:0007005 156 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
cranial nerve development GO:0021545 4 0.016
muscle system process GO:0003012 81 0.016
regulation of cellular response to growth factor stimulus GO:0090287 76 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of actin filament polymerization GO:0030833 50 0.016
Worm
regulation of metal ion transport GO:0010959 120 0.016
nitrogen compound transport GO:0071705 191 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
innate immune response GO:0045087 178 0.016
positive regulation of neural precursor cell proliferation GO:2000179 2 0.015
cell migration involved in gastrulation GO:0042074 1 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
Worm Fly
response to organic cyclic compound GO:0014070 204 0.015
protein depolymerization GO:0051261 30 0.015
regulation of cell substrate adhesion GO:0010810 68 0.015
circadian behavior GO:0048512 2 0.015
blood circulation GO:0008015 113 0.015
positive regulation of protein localization to nucleus GO:1900182 48 0.015
regulation of protein targeting GO:1903533 91 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
visual behavior GO:0007632 2 0.015
tube morphogenesis GO:0035239 95 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
spermatid development GO:0007286 4 0.015
cellular divalent inorganic cation homeostasis GO:0072503 128 0.015
tissue migration GO:0090130 119 0.015
negative regulation of protein maturation GO:1903318 142 0.015
regulation of canonical wnt signaling pathway GO:0060828 88 0.015
regulation of cell shape GO:0008360 48 0.015
myoblast fusion GO:0007520 1 0.015
establishment of planar polarity GO:0001736 3 0.015
maintenance of location in cell GO:0051651 62 0.015

TRIO disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.033
central nervous system disease DOID:331 186 0.030
nervous system disease DOID:863 431 0.030
disease of mental health DOID:150 70 0.030
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026
cardiovascular system disease DOID:1287 106 0.023
organ system cancer DOID:0050686 164 0.022
bone disease DOID:0080001 88 0.019
connective tissue disease DOID:65 109 0.019
neurodegenerative disease DOID:1289 102 0.018
sensory system disease DOID:0050155 203 0.017
immune system disease DOID:2914 155 0.017
osteochondrodysplasia DOID:2256 35 0.017
bone development disease DOID:0080006 55 0.017
myopathy DOID:423 104 0.015
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.015