Homo sapiens

33 known processes

BCKDHB

branched chain keto acid dehydrogenase E1, beta polypeptide

(Aliases: E1B,FLJ17880,dJ279A18.1)

BCKDHB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
branched chain amino acid metabolic process GO:0009081 4 0.941
organic acid catabolic process GO:0016054 71 0.925
small molecule catabolic process GO:0044282 92 0.785
cellular amino acid metabolic process GO:0006520 116 0.512
carboxylic acid catabolic process GO:0046395 71 0.512
oxidation reduction process GO:0055114 396 0.489
Mouse
lipid oxidation GO:0034440 33 0.482
branched chain amino acid catabolic process GO:0009083 4 0.443
cellular lipid metabolic process GO:0044255 303 0.428
lipid metabolic process GO:0006629 381 0.409
cellular amino acid catabolic process GO:0009063 31 0.265
monocarboxylic acid metabolic process GO:0032787 185 0.185
fatty acid metabolic process GO:0006631 115 0.170
monocarboxylic acid catabolic process GO:0072329 37 0.148
post embryonic development GO:0009791 2 0.148
lipid modification GO:0030258 84 0.140
lipid biosynthetic process GO:0008610 177 0.136
fatty acid catabolic process GO:0009062 29 0.131
small molecule biosynthetic process GO:0044283 157 0.119
cellular lipid catabolic process GO:0044242 65 0.118
cellular ketone metabolic process GO:0042180 80 0.115
cofactor metabolic process GO:0051186 87 0.075
ribonucleoside monophosphate metabolic process GO:0009161 187 0.067
ribonucleoside triphosphate metabolic process GO:0009199 412 0.066
multicellular organismal aging GO:0010259 3 0.061
organic acid biosynthetic process GO:0016053 97 0.059
regulation of cellular ketone metabolic process GO:0010565 50 0.058
determination of adult lifespan GO:0008340 2 0.055
sulfur compound metabolic process GO:0006790 101 0.054
organic hydroxy compound metabolic process GO:1901615 147 0.052
fatty acid oxidation GO:0019395 31 0.050
peroxisome organization GO:0007031 28 0.049
intracellular protein transmembrane import GO:0044743 23 0.045
response to oxygen containing compound GO:1901700 369 0.044
Rat
lipid catabolic process GO:0016042 84 0.044
transmembrane transport GO:0055085 399 0.044
alpha amino acid metabolic process GO:1901605 72 0.044
nucleoside triphosphate metabolic process GO:0009141 422 0.039
fatty acid beta oxidation GO:0006635 22 0.039
regulation of hormone levels GO:0010817 125 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.037
secretion by cell GO:0032940 226 0.036
anion transport GO:0006820 161 0.033
reactive oxygen species metabolic process GO:0072593 75 0.033
cellular modified amino acid metabolic process GO:0006575 64 0.033
protein targeting to peroxisome GO:0006625 15 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
organic hydroxy compound biosynthetic process GO:1901617 71 0.032
negative regulation of protein metabolic process GO:0051248 391 0.032
regulation of secretion GO:0051046 194 0.031
amine metabolic process GO:0009308 44 0.031
nucleoside monophosphate metabolic process GO:0009123 191 0.031
intracellular protein transmembrane transport GO:0065002 24 0.031
cellular amine metabolic process GO:0044106 41 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
chemical homeostasis GO:0048878 306 0.030
membrane organization GO:0061024 292 0.030
carbohydrate metabolic process GO:0005975 207 0.029
organophosphate biosynthetic process GO:0090407 163 0.028
single organism cellular localization GO:1902580 332 0.028
ribonucleoside catabolic process GO:0042454 406 0.027
protein homooligomerization GO:0051260 100 0.027
alcohol metabolic process GO:0006066 114 0.027
coenzyme metabolic process GO:0006732 65 0.027
organophosphate ester transport GO:0015748 32 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
single organism membrane organization GO:0044802 268 0.026
negative regulation of catalytic activity GO:0043086 335 0.025
alpha amino acid catabolic process GO:1901606 26 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
fatty acid beta oxidation using acyl coa dehydrogenase GO:0033539 3 0.024
guanosine containing compound metabolic process GO:1901068 244 0.023
regulation of peptide secretion GO:0002791 42 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
positive regulation of transport GO:0051050 336 0.023
secretion GO:0046903 254 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
carboxylic acid biosynthetic process GO:0046394 97 0.022
sterol transport GO:0015918 39 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
protein oligomerization GO:0051259 173 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
memory GO:0007613 3 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
system process GO:0003008 349 0.021
defense response GO:0006952 315 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
atp metabolic process GO:0046034 176 0.021
regulation of transferase activity GO:0051338 355 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.020
protein targeting GO:0006605 187 0.020
organophosphate catabolic process GO:0046434 430 0.020
female gamete generation GO:0007292 2 0.020
diterpenoid metabolic process GO:0016101 20 0.020
protein processing GO:0016485 226 0.020
intracellular protein transport GO:0006886 270 0.020
immune response GO:0006955 307 0.020
peroxisomal transport GO:0043574 15 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
innate immune response GO:0045087 178 0.019
cofactor biosynthetic process GO:0051188 31 0.019
response to inorganic substance GO:0010035 127 0.019
cytoplasmic transport GO:0016482 379 0.019
spermatid differentiation GO:0048515 4 0.019
mitochondrion organization GO:0007005 156 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
organic anion transport GO:0015711 103 0.018
lipid localization GO:0010876 106 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
nervous system development GO:0007399 293 0.018
response to hormone GO:0009725 175 0.018
Rat
regulation of hormone secretion GO:0046883 57 0.018
response to other organism GO:0051707 261 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
protein import GO:0017038 130 0.017
lipid transport GO:0006869 90 0.017
nitrogen compound transport GO:0071705 191 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
protein localization to membrane GO:0072657 160 0.017
hormone transport GO:0009914 68 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
positive regulation of catabolic process GO:0009896 310 0.017
response to biotic stimulus GO:0009607 276 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
segmentation GO:0035282 4 0.017
protein localization to organelle GO:0033365 280 0.017
hormone secretion GO:0046879 65 0.017
negative regulation of transport GO:0051051 176 0.017
monocarboxylic acid biosynthetic process GO:0072330 67 0.017
steroid biosynthetic process GO:0006694 46 0.016
nucleotide catabolic process GO:0009166 408 0.016
vesicle mediated transport GO:0016192 371 0.016
regulation of membrane potential GO:0042391 95 0.016
endomembrane system organization GO:0010256 196 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
negative regulation of transferase activity GO:0051348 124 0.015
neuromuscular junction development GO:0007528 3 0.015
thioester metabolic process GO:0035383 23 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
ossification GO:0001503 121 0.015
neurological system process GO:0050877 163 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
insulin secretion GO:0030073 39 0.015
regulation of intracellular transport GO:0032386 195 0.015
ion transmembrane transport GO:0034220 338 0.015
cellular macromolecular complex assembly GO:0034622 324 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
nucleoside catabolic process GO:0009164 408 0.014
spermatid development GO:0007286 4 0.014
regulation of proteolysis GO:0030162 293 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
regulation of kinase activity GO:0043549 314 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
response to activity GO:0014823 0 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
blastoderm segmentation GO:0007350 2 0.014
oogenesis GO:0048477 2 0.014
neurogenesis GO:0022008 169 0.014
ras protein signal transduction GO:0007265 73 0.014
acyl coa metabolic process GO:0006637 23 0.014
gtp metabolic process GO:0046039 239 0.014
replacement ossification GO:0036075 1 0.014
purine containing compound catabolic process GO:0072523 411 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
protein homotetramerization GO:0051289 28 0.014
response to abiotic stimulus GO:0009628 336 0.014
maintenance of location GO:0051235 112 0.013
cellular amide metabolic process GO:0043603 69 0.013
regulation of protein localization GO:0032880 296 0.013
cellular hormone metabolic process GO:0034754 41 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
regulation of protein kinase activity GO:0045859 289 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
cellular chemical homeostasis GO:0055082 180 0.013
regeneration GO:0031099 4 0.013
negative regulation of protein modification process GO:0031400 200 0.013
glycerolipid metabolic process GO:0046486 107 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
response to nitrogen compound GO:1901698 184 0.013
Rat
negative regulation of hydrolase activity GO:0051346 182 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
regulation of cholesterol metabolic process GO:0090181 4 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of lipid biosynthetic process GO:0046890 47 0.012
peptide transport GO:0015833 74 0.012
phospholipid metabolic process GO:0006644 99 0.012
organic hydroxy compound transport GO:0015850 63 0.012
peripheral nervous system development GO:0007422 2 0.012
protein maturation GO:0051604 233 0.012
regulation of homeostatic process GO:0032844 121 0.012
steroid metabolic process GO:0008202 94 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
plasma membrane organization GO:0007009 115 0.012
ketone biosynthetic process GO:0042181 17 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
c21 steroid hormone biosynthetic process GO:0006700 11 0.012
cellular homeostasis GO:0019725 196 0.012
response to bacterium GO:0009617 144 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of cytokine production GO:0001817 232 0.012
response to organic cyclic compound GO:0014070 204 0.012
Rat
purine nucleoside catabolic process GO:0006152 398 0.012
positive regulation of blood pressure GO:0045777 3 0.012
hormone metabolic process GO:0042445 61 0.011
locomotory behavior GO:0007626 1 0.011
dephosphorylation GO:0016311 209 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
ion homeostasis GO:0050801 230 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
response to external biotic stimulus GO:0043207 261 0.011
protein localization to peroxisome GO:0072662 15 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
protein localization to plasma membrane GO:0072659 93 0.011
regulation of protein maturation GO:1903317 150 0.011
response to organonitrogen compound GO:0010243 156 0.011
Rat
regulation of lipid metabolic process GO:0019216 96 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
gtp catabolic process GO:0006184 237 0.011
cholesterol transport GO:0030301 39 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
microtubule based process GO:0007017 210 0.011
regulation of cell differentiation GO:0045595 393 0.011
response to drug GO:0042493 81 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
neural tube formation GO:0001841 3 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
protein catabolic process GO:0030163 325 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
alcohol biosynthetic process GO:0046165 52 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
amide transport GO:0042886 76 0.010
regulation of response to external stimulus GO:0032101 222 0.010
regulation of protein transport GO:0051223 213 0.010
positive regulation of organelle organization GO:0010638 195 0.010
regulation of cell cycle GO:0051726 393 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
rho protein signal transduction GO:0007266 26 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
peptide hormone secretion GO:0030072 50 0.010
response to lipid GO:0033993 206 0.010
Rat
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
negative regulation of protein maturation GO:1903318 142 0.010
phospholipid transport GO:0015914 23 0.010
endocytosis GO:0006897 159 0.010
apoptotic signaling pathway GO:0097190 268 0.010
purine containing compound biosynthetic process GO:0072522 88 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010

BCKDHB disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.988
inherited metabolic disorder DOID:655 242 0.988
amino acid metabolic disorder DOID:9252 50 0.955
organic acidemia DOID:0060159 14 0.167
carbohydrate metabolic disorder DOID:2978 55 0.028
hyperinsulinemic hypoglycemia DOID:13317 7 0.025
disease of cellular proliferation DOID:14566 174 0.018
cancer DOID:162 167 0.017
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
immune system disease DOID:2914 155 0.014
hematopoietic system disease DOID:74 100 0.014
organ system cancer DOID:0050686 164 0.013
eye and adnexa disease DOID:1492 150 0.012
cardiovascular system disease DOID:1287 106 0.012
central nervous system disease DOID:331 186 0.011
eye disease DOID:5614 149 0.011
musculoskeletal system disease DOID:17 223 0.011
maple syrup urine disease DOID:9269 5 0.001