Homo sapiens

34 known processes

BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

(Aliases: MSUD1,MSU,BCKDE1A,OVD1A,FLJ45695)

BCKDHA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 71 0.272
coenzyme metabolic process GO:0006732 65 0.218
response to lipid GO:0033993 206 0.160
small molecule catabolic process GO:0044282 92 0.153
organic acid catabolic process GO:0016054 71 0.112
oxidation reduction process GO:0055114 396 0.109
branched chain amino acid metabolic process GO:0009081 4 0.100
post embryonic development GO:0009791 2 0.089
small molecule biosynthetic process GO:0044283 157 0.076
lipid metabolic process GO:0006629 381 0.069
cofactor metabolic process GO:0051186 87 0.069
response to oxygen containing compound GO:1901700 369 0.068
cellular amino acid metabolic process GO:0006520 116 0.063
cellular lipid metabolic process GO:0044255 303 0.056
multicellular organismal aging GO:0010259 3 0.055
determination of adult lifespan GO:0008340 2 0.050
cellular amino acid catabolic process GO:0009063 31 0.048
epithelial cell differentiation GO:0030855 141 0.046
fatty acid metabolic process GO:0006631 115 0.046
cellular ketone metabolic process GO:0042180 80 0.044
fatty acid biosynthetic process GO:0006633 46 0.042
response to hormone GO:0009725 175 0.042
cellular amine metabolic process GO:0044106 41 0.042
carbohydrate metabolic process GO:0005975 207 0.042
generation of precursor metabolites and energy GO:0006091 68 0.041
monocarboxylic acid metabolic process GO:0032787 185 0.041
amine metabolic process GO:0009308 44 0.038
female gamete generation GO:0007292 2 0.038
cellular protein complex assembly GO:0043623 188 0.037
lipid biosynthetic process GO:0008610 177 0.036
response to organic cyclic compound GO:0014070 204 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.034
lipid catabolic process GO:0016042 84 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
phosphatidylethanolamine biosynthetic process GO:0006646 4 0.032
cellular macromolecular complex assembly GO:0034622 324 0.030
response to nutrient levels GO:0031667 81 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
alcohol metabolic process GO:0006066 114 0.026
ribonucleoside monophosphate metabolic process GO:0009161 187 0.026
purine containing compound catabolic process GO:0072523 411 0.026
dicarboxylic acid metabolic process GO:0043648 29 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
mitochondrion organization GO:0007005 156 0.025
carboxylic acid biosynthetic process GO:0046394 97 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
isocitrate metabolic process GO:0006102 1 0.024
cytoplasmic transport GO:0016482 379 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
organophosphate catabolic process GO:0046434 430 0.024
oogenesis GO:0048477 2 0.024
tricarboxylic acid cycle GO:0006099 4 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
response to biotic stimulus GO:0009607 276 0.023
nucleotide catabolic process GO:0009166 408 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
atp metabolic process GO:0046034 176 0.022
response to organonitrogen compound GO:0010243 156 0.022
response to external biotic stimulus GO:0043207 261 0.022
response to abiotic stimulus GO:0009628 336 0.021
monocarboxylic acid biosynthetic process GO:0072330 67 0.021
fatty acid catabolic process GO:0009062 29 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
cellular lipid catabolic process GO:0044242 65 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
response to camp GO:0051591 25 0.021
oxidoreduction coenzyme metabolic process GO:0006733 19 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
response to nitrogen compound GO:1901698 184 0.020
lipid oxidation GO:0034440 33 0.019
mitochondrial respiratory chain complex assembly GO:0033108 23 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
neuroblast proliferation GO:0007405 4 0.019
myosin filament assembly GO:0031034 2 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
maintenance of location GO:0051235 112 0.018
defense response GO:0006952 315 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
positive regulation of immune system process GO:0002684 283 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.017
response to extracellular stimulus GO:0009991 85 0.017
glycerolipid metabolic process GO:0046486 107 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
tricarboxylic acid metabolic process GO:0072350 4 0.017
secretion by cell GO:0032940 226 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
rna processing GO:0006396 255 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
purine containing compound biosynthetic process GO:0072522 88 0.016
regulation of dna metabolic process GO:0051052 153 0.016
segmentation GO:0035282 4 0.016
microtubule based process GO:0007017 210 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
nitrogen compound transport GO:0071705 191 0.016
mitotic cell cycle process GO:1903047 286 0.016
dna repair GO:0006281 198 0.016
regeneration GO:0031099 4 0.016
protein catabolic process GO:0030163 325 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
ras protein signal transduction GO:0007265 73 0.015
adult locomotory behavior GO:0008344 1 0.015
dephosphorylation GO:0016311 209 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to starvation GO:0042594 59 0.015
protein ubiquitination GO:0016567 314 0.014
sensory perception of pain GO:0019233 4 0.014
organic acid biosynthetic process GO:0016053 97 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
neurogenesis GO:0022008 169 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
system process GO:0003008 349 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
fatty acid oxidation GO:0019395 31 0.014
response to axon injury GO:0048678 1 0.014
regulation of proteolysis GO:0030162 293 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
nucleoside catabolic process GO:0009164 408 0.014
cellular protein catabolic process GO:0044257 261 0.014
protein tetramerization GO:0051262 47 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
membrane organization GO:0061024 292 0.014
apoptotic signaling pathway GO:0097190 268 0.013
citrate metabolic process GO:0006101 2 0.013
regulation of cell cycle process GO:0010564 266 0.013
organelle assembly GO:0070925 176 0.013
secretion GO:0046903 254 0.013
2 oxoglutarate metabolic process GO:0006103 4 0.013
nervous system development GO:0007399 293 0.013
protein maturation GO:0051604 233 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
cell morphogenesis GO:0000902 296 0.013
fatty acid beta oxidation GO:0006635 22 0.013
rna interference GO:0016246 4 0.013
memory GO:0007613 3 0.013
axon cargo transport GO:0008088 2 0.012
response to organophosphorus GO:0046683 41 0.012
single organism membrane organization GO:0044802 268 0.012
positive regulation of catabolic process GO:0009896 310 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
regulation of cellular component movement GO:0051270 334 0.012
positive regulation of transport GO:0051050 336 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
response to oxidative stress GO:0006979 121 0.012
metencephalon development GO:0022037 2 0.012
response to other organism GO:0051707 261 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
response to drug GO:0042493 81 0.012
response to acid chemical GO:0001101 66 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
peripheral nervous system development GO:0007422 2 0.012
regulation of cell cycle GO:0051726 393 0.012
regulation of cellular response to stress GO:0080135 244 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
associative learning GO:0008306 1 0.012
response to cytokine GO:0034097 232 0.012
glycerolipid biosynthetic process GO:0045017 51 0.011
regulation of peptidase activity GO:0052547 180 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
hexose metabolic process GO:0019318 55 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of transferase activity GO:0051338 355 0.011
regulation of response to external stimulus GO:0032101 222 0.011
response to decreased oxygen levels GO:0036293 96 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
protein acetylation GO:0006473 116 0.011
innate immune response GO:0045087 178 0.011
response to steroid hormone GO:0048545 80 0.011
protein localization to organelle GO:0033365 280 0.011
neurological system process GO:0050877 163 0.011
chemical homeostasis GO:0048878 306 0.011
regulation of cell differentiation GO:0045595 393 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
mitotic cell cycle GO:0000278 326 0.011
blastoderm segmentation GO:0007350 2 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
dna recombination GO:0006310 77 0.011
immune effector process GO:0002252 159 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
protein oligomerization GO:0051259 173 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of cytokine production GO:0001817 232 0.011
immune response GO:0006955 307 0.010
response to virus GO:0009615 126 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
ribonucleotide biosynthetic process GO:0009260 81 0.010
dna catabolic process GO:0006308 49 0.010
actin filament based process GO:0030029 224 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
cellular response to lipid GO:0071396 127 0.010
sulfur compound metabolic process GO:0006790 101 0.010
single organism cellular localization GO:1902580 332 0.010
biological adhesion GO:0022610 331 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
negative regulation of transferase activity GO:0051348 124 0.010
negative regulation of protein maturation GO:1903318 142 0.010
cofactor biosynthetic process GO:0051188 31 0.010
negative regulation of cell death GO:0060548 345 0.010
inner ear morphogenesis GO:0042472 4 0.010
cellular component morphogenesis GO:0032989 314 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
embryo development GO:0009790 123 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
cell adhesion GO:0007155 325 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010

BCKDHA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.425
inherited metabolic disorder DOID:655 242 0.425
amino acid metabolic disorder DOID:9252 50 0.042
organic acidemia DOID:0060159 14 0.042
central nervous system disease DOID:331 186 0.025
nervous system disease DOID:863 431 0.025
immune system disease DOID:2914 155 0.024
sensory system disease DOID:0050155 203 0.019
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
neurodegenerative disease DOID:1289 102 0.018
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
musculoskeletal system disease DOID:17 223 0.015
carbohydrate metabolic disorder DOID:2978 55 0.014
retinal disease DOID:5679 118 0.012
connective tissue disease DOID:65 109 0.011
brain disease DOID:936 73 0.011
maple syrup urine disease DOID:9269 5 0.002