Homo sapiens

0 known processes

HECTD1

HECT domain containing 1

(Aliases: KIAA1131,FLJ38315)

HECTD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.167
purine nucleotide catabolic process GO:0006195 405 0.126
regulation of wnt signaling pathway GO:0030111 123 0.122
actin filament based process GO:0030029 224 0.121
wnt signaling pathway GO:0016055 156 0.114
purine nucleoside triphosphate catabolic process GO:0009146 392 0.112
positive regulation of catabolic process GO:0009896 310 0.109
female gamete generation GO:0007292 2 0.094
regulation of cytokine production GO:0001817 232 0.093
apoptotic signaling pathway GO:0097190 268 0.093
cytokine production GO:0001816 247 0.091
protein polyubiquitination GO:0000209 110 0.089
Human
regulation of protein localization GO:0032880 296 0.085
cellular macromolecule catabolic process GO:0044265 380 0.081
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.081
Human
cellular macromolecular complex assembly GO:0034622 324 0.080
cellular ketone metabolic process GO:0042180 80 0.080
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.078
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.077
protein modification by small protein conjugation GO:0032446 342 0.077
Human
positive regulation of protein catabolic process GO:0045732 75 0.076
immune response GO:0006955 307 0.076
actin cytoskeleton organization GO:0030036 207 0.071
positive regulation of cellular component organization GO:0051130 376 0.071
cellular component morphogenesis GO:0032989 314 0.066
ras protein signal transduction GO:0007265 73 0.065
oogenesis GO:0048477 2 0.064
cellular amine metabolic process GO:0044106 41 0.063
cellular protein catabolic process GO:0044257 261 0.062
Human
response to oxygen containing compound GO:1901700 369 0.060
nucleotide catabolic process GO:0009166 408 0.058
innate immune response GO:0045087 178 0.055
positive regulation of immune system process GO:0002684 283 0.055
protein modification by small protein removal GO:0070646 92 0.055
cell development GO:0048468 328 0.053
regulation of protein catabolic process GO:0042176 155 0.053
regulation of cell morphogenesis GO:0022604 153 0.053
regulation of gtp catabolic process GO:0033124 180 0.053
protein ubiquitination GO:0016567 314 0.050
Human
response to other organism GO:0051707 261 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.050
immune response regulating signaling pathway GO:0002764 97 0.050
nucleoside catabolic process GO:0009164 408 0.049
cell morphogenesis GO:0000902 296 0.048
response to biotic stimulus GO:0009607 276 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.047
positive regulation of nucleoside metabolic process GO:0045979 186 0.046
regulation of immune response GO:0050776 201 0.045
dephosphorylation GO:0016311 209 0.045
protein deubiquitination GO:0016579 79 0.045
cellular response to lipid GO:0071396 127 0.045
nucleoside triphosphate metabolic process GO:0009141 422 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
regulation of response to external stimulus GO:0032101 222 0.044
ribonucleoside triphosphate metabolic process GO:0009199 412 0.044
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
posttranscriptional regulation of gene expression GO:0010608 213 0.042
positive regulation of wnt signaling pathway GO:0030177 54 0.042
translation GO:0006412 132 0.042
response to external biotic stimulus GO:0043207 261 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
regulation of multi organism process GO:0043900 157 0.040
negative regulation of intracellular signal transduction GO:1902532 183 0.040
microtubule based process GO:0007017 210 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
positive regulation of phosphorylation GO:0042327 394 0.039
regulation of cell cycle GO:0051726 393 0.039
mitotic cell cycle process GO:1903047 286 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.038
amine metabolic process GO:0009308 44 0.038
negative regulation of programmed cell death GO:0043069 321 0.038
mitotic cell cycle GO:0000278 326 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
signal transduction by phosphorylation GO:0023014 297 0.037
cellular response to oxygen containing compound GO:1901701 276 0.037
regulation of ras protein signal transduction GO:0046578 155 0.037
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.037
regulation of protein complex assembly GO:0043254 147 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
small gtpase mediated signal transduction GO:0007264 78 0.036
protein localization to organelle GO:0033365 280 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
modification dependent macromolecule catabolic process GO:0043632 212 0.035
Human
cytoplasmic transport GO:0016482 379 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.034
activation of immune response GO:0002253 114 0.034
vesicle mediated transport GO:0016192 371 0.034
negative regulation of apoptotic process GO:0043066 316 0.033
organ morphogenesis GO:0009887 147 0.033
regulation of odontogenesis GO:0042481 4 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.033
positive regulation of hydrolase activity GO:0051345 331 0.032
positive regulation of nucleotide catabolic process GO:0030813 185 0.032
protein catabolic process GO:0030163 325 0.032
Human
cellular protein complex assembly GO:0043623 188 0.032
gtp catabolic process GO:0006184 237 0.032
regulation of protein ubiquitination GO:0031396 95 0.031
Human
negative regulation of toll like receptor 3 signaling pathway GO:0034140 2 0.031
locomotory behavior GO:0007626 1 0.031
system process GO:0003008 349 0.031
positive regulation of protein phosphorylation GO:0001934 313 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
negative regulation of apoptotic signaling pathway GO:2001234 97 0.030
positive regulation of organelle organization GO:0010638 195 0.030
response to lipid GO:0033993 206 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
rho protein signal transduction GO:0007266 26 0.030
negative regulation of immune system process GO:0002683 136 0.029
positive regulation of immune response GO:0050778 159 0.029
hindbrain development GO:0030902 3 0.029
endomembrane system organization GO:0010256 196 0.028
positive regulation of innate immune response GO:0045089 79 0.028
regulation of response to biotic stimulus GO:0002831 55 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
mapk cascade GO:0000165 288 0.028
regulation of transferase activity GO:0051338 355 0.028
positive regulation of gtpase activity GO:0043547 166 0.028
interleukin 2 production GO:0032623 20 0.027
regulation of cell cycle process GO:0010564 266 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
negative regulation of cell death GO:0060548 345 0.027
determination of adult lifespan GO:0008340 2 0.027
protein autophosphorylation GO:0046777 123 0.027
blastoderm segmentation GO:0007350 2 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
i kappab kinase nf kappab signaling GO:0007249 166 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.026
regulation of innate immune response GO:0045088 97 0.026
positive regulation of transport GO:0051050 336 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
positive regulation of cell death GO:0010942 263 0.025
regulation of apoptotic signaling pathway GO:2001233 175 0.025
regulation of defense response GO:0031347 154 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
multicellular organismal aging GO:0010259 3 0.025
negative regulation of protein modification process GO:0031400 200 0.024
Human
purine nucleoside catabolic process GO:0006152 398 0.024
immune system development GO:0002520 195 0.024
nitrogen compound transport GO:0071705 191 0.024
guanosine containing compound metabolic process GO:1901068 244 0.024
gtp metabolic process GO:0046039 239 0.024
positive regulation of gtp catabolic process GO:0033126 166 0.024
regulation of vesicle mediated transport GO:0060627 130 0.024
ribonucleoside catabolic process GO:0042454 406 0.023
protein oligomerization GO:0051259 173 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
maintenance of location GO:0051235 112 0.023
protein k48 linked ubiquitination GO:0070936 38 0.023
activation of innate immune response GO:0002218 55 0.023
extrinsic apoptotic signaling pathway GO:0097191 119 0.022
organelle assembly GO:0070925 176 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of protein localization to nucleus GO:1900180 85 0.022
positive regulation of defense response GO:0031349 87 0.022
regulation of cell differentiation GO:0045595 393 0.022
regulation of dephosphorylation GO:0035303 96 0.022
oocyte development GO:0048599 1 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
purine containing compound catabolic process GO:0072523 411 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
response to bacterium GO:0009617 144 0.021
anterior posterior axis specification GO:0009948 2 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
protein processing GO:0016485 226 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
nuclear division GO:0000280 128 0.021
regulation of mapk cascade GO:0043408 262 0.021
organophosphate catabolic process GO:0046434 430 0.021
dna repair GO:0006281 198 0.021
Human
ribonucleotide catabolic process GO:0009261 405 0.021
nervous system development GO:0007399 293 0.021
Mouse
regulation of protein kinase activity GO:0045859 289 0.020
pattern recognition receptor signaling pathway GO:0002221 48 0.020
organelle localization GO:0051640 84 0.020
protein maturation GO:0051604 233 0.020
chromatin organization GO:0006325 351 0.020
Human
positive regulation of apoptotic process GO:0043065 246 0.020
immune response activating signal transduction GO:0002757 90 0.020
protein localization to nucleus GO:0034504 136 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.019
oocyte differentiation GO:0009994 2 0.019
cellular response to biotic stimulus GO:0071216 71 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
microtubule cytoskeleton organization GO:0000226 176 0.019
negative regulation of protein ubiquitination GO:0031397 35 0.019
Human
response to abiotic stimulus GO:0009628 336 0.019
secretion GO:0046903 254 0.019
regulation of cellular response to stress GO:0080135 244 0.019
Human
salivary gland morphogenesis GO:0007435 4 0.019
defense response GO:0006952 315 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
response to organic cyclic compound GO:0014070 204 0.019
metal ion transport GO:0030001 272 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
intracellular protein transport GO:0006886 270 0.019
regulation of translational elongation GO:0006448 2 0.019
cell division GO:0051301 168 0.018
positive regulation of protein complex assembly GO:0031334 86 0.018
spermatid differentiation GO:0048515 4 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
positive regulation of transferase activity GO:0051347 227 0.018
regulation of microtubule based process GO:0032886 74 0.018
negative regulation of protein maturation GO:1903318 142 0.018
regulation of proteolysis GO:0030162 293 0.018
secretion by cell GO:0032940 226 0.018
hemopoiesis GO:0030097 180 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
regulation of growth GO:0040008 165 0.017
neural tube formation GO:0001841 3 0.017
Mouse
chemical homeostasis GO:0048878 306 0.017
negative regulation of proteolysis GO:0045861 132 0.017
chromatin modification GO:0016568 298 0.017
Human
spermatid development GO:0007286 4 0.017
response to molecule of bacterial origin GO:0002237 82 0.017
regulation of protein maturation GO:1903317 150 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
innate immune response activating signal transduction GO:0002758 48 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
Mouse
anatomical structure homeostasis GO:0060249 100 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
neuromuscular junction development GO:0007528 3 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
single organism cellular localization GO:1902580 332 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
memory GO:0007613 3 0.015
cellular lipid metabolic process GO:0044255 303 0.015
negative regulation of cytokine production GO:0001818 82 0.015
peripheral nervous system development GO:0007422 2 0.015
growth GO:0040007 202 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
regulation of interleukin 8 production GO:0032677 49 0.015
lipid metabolic process GO:0006629 381 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
retrograde transport endosome to golgi GO:0042147 45 0.015
regulation of secretion by cell GO:1903530 177 0.015
protein k48 linked deubiquitination GO:0071108 19 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of kinase activity GO:0043549 314 0.015
positive regulation of cytokine production GO:0001819 167 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.015
neurogenesis GO:0022008 169 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.015
neurological system process GO:0050877 163 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
Human
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
Human
modification dependent protein catabolic process GO:0019941 209 0.015
Human
adult locomotory behavior GO:0008344 1 0.015
endocytosis GO:0006897 159 0.015
negative regulation of cell cycle GO:0045786 193 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
segmentation GO:0035282 4 0.014
response to nitrogen compound GO:1901698 184 0.014
muscle cell proliferation GO:0033002 35 0.014
regeneration GO:0031099 4 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
cation transport GO:0006812 331 0.014
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
protein import GO:0017038 130 0.014
activation of protein kinase activity GO:0032147 90 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
nuclear transport GO:0051169 179 0.014
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
canonical wnt signaling pathway GO:0060070 116 0.014
myosin filament assembly GO:0031034 2 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
Mouse
circulatory system development GO:0072359 262 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
regulation of translation GO:0006417 89 0.014
regulation of intracellular transport GO:0032386 195 0.014
response to growth factor GO:0070848 205 0.014
negative regulation of transport GO:0051051 176 0.014
neuroblast proliferation GO:0007405 4 0.014
negative regulation of protein processing GO:0010955 142 0.014
regulation of gtpase activity GO:0043087 180 0.013
cell fate determination GO:0001709 3 0.013
regulation of endocytosis GO:0030100 72 0.013
negative regulation of catabolic process GO:0009895 104 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
cerebellum development GO:0021549 2 0.013
ion homeostasis GO:0050801 230 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
peptidyl lysine modification GO:0018205 144 0.013
myosin filament organization GO:0031033 2 0.013
regulation of dna metabolic process GO:0051052 153 0.013
Human
glutamate metabolic process GO:0006536 10 0.013
muscle cell cellular homeostasis GO:0046716 3 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
Human
atp metabolic process GO:0046034 176 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.012
protein targeting GO:0006605 187 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
protein k63 linked deubiquitination GO:0070536 21 0.012
cell cycle phase transition GO:0044770 173 0.012
single organism membrane organization GO:0044802 268 0.012
cell projection organization GO:0030030 252 0.012
regulation of microtubule cytoskeleton organization GO:0070507 61 0.012
cation transmembrane transport GO:0098655 238 0.012
ion transmembrane transport GO:0034220 338 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
cellular response to lipopolysaccharide GO:0071222 57 0.012
tripartite regional subdivision GO:0007351 2 0.012
cellular homeostasis GO:0019725 196 0.012
organelle fission GO:0048285 149 0.012
biological adhesion GO:0022610 331 0.012
thymus development GO:0048538 3 0.012
carbohydrate metabolic process GO:0005975 207 0.012
rna processing GO:0006396 255 0.012
transmembrane transport GO:0055085 399 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
mrna metabolic process GO:0016071 175 0.012
oxidation reduction process GO:0055114 396 0.012
positive regulation of kinase activity GO:0033674 204 0.012
immune effector process GO:0002252 159 0.012
regulation of protein targeting GO:1903533 91 0.012
protein localization to membrane GO:0072657 160 0.012
primary neural tube formation GO:0014020 3 0.012
Mouse
glycosylation GO:0070085 71 0.012
regulation of cd40 signaling pathway GO:2000348 3 0.012
positive regulation of developmental process GO:0051094 314 0.012
regulation of membrane potential GO:0042391 95 0.012
response to lipopolysaccharide GO:0032496 70 0.012
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
membrane organization GO:0061024 292 0.011
endosomal transport GO:0016197 129 0.011
cell projection morphogenesis GO:0048858 129 0.011
negative regulation of organelle organization GO:0010639 126 0.011
Human
golgi vesicle transport GO:0048193 80 0.011
metencephalon development GO:0022037 2 0.011
tube development GO:0035295 125 0.011
Mouse
associative learning GO:0008306 1 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
rhythmic behavior GO:0007622 2 0.011
cellular chemical homeostasis GO:0055082 180 0.011
tube closure GO:0060606 3 0.011
Mouse
regulation of neurogenesis GO:0050767 82 0.011
regulation of chromosome organization GO:0033044 103 0.011
Human
regulation of cell adhesion GO:0030155 166 0.011
negative regulation of protein localization to nucleus GO:1900181 34 0.011
cell part morphogenesis GO:0032990 137 0.011
negative regulation of developmental process GO:0051093 247 0.011
regulation of protein processing GO:0070613 150 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
response to radiation GO:0009314 151 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
cell substrate adhesion GO:0031589 132 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.011
Human
central nervous system development GO:0007417 123 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
rna interference GO:0016246 4 0.011
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 7 0.011
lipid localization GO:0010876 106 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
response to wounding GO:0009611 168 0.011
microtubule organizing center organization GO:0031023 62 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
mitotic nuclear division GO:0007067 119 0.011
cell junction assembly GO:0034329 67 0.011
leukocyte activation GO:0045321 164 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
reproductive process GO:0022414 106 0.010
interleukin 8 production GO:0032637 51 0.010
neural crest cell development GO:0014032 3 0.010
atp catabolic process GO:0006200 157 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
tissue regeneration GO:0042246 3 0.010
meiosis i GO:0007127 4 0.010
actin filament organization GO:0007015 128 0.010
mitotic spindle elongation GO:0000022 4 0.010
regulation of leukocyte activation GO:0002694 115 0.010
lymphocyte activation GO:0046649 133 0.010
ossification GO:0001503 121 0.010
cellular response to molecule of bacterial origin GO:0071219 62 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.010
protein homooligomerization GO:0051260 100 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
histone modification GO:0016570 251 0.010
Human
divalent inorganic cation homeostasis GO:0072507 136 0.010
negative regulation of cell cycle process GO:0010948 121 0.010

HECTD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.022
cancer DOID:162 167 0.021
organ system cancer DOID:0050686 164 0.021
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
disease of metabolism DOID:0014667 295 0.013
central nervous system disease DOID:331 186 0.011
neurodegenerative disease DOID:1289 102 0.010