Homo sapiens

55 known processes

CACNA1C

calcium channel, voltage-dependent, L type, alpha 1C subunit

(Aliases: MGC120730,CCHL1A1,CaV1.2,CACN2,CACNL1A1,TS,CACH2)

CACNA1C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of voltage gated calcium channel activity GO:1901386 4 1.000
calcium ion transmembrane transport GO:0070588 76 0.989
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.962
regulation of ion transmembrane transport GO:0034765 132 0.902
ion transmembrane transport GO:0034220 338 0.896
calcium ion transport GO:0006816 147 0.863
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.861
regulation of transmembrane transport GO:0034762 139 0.813
metal ion transport GO:0030001 272 0.807
regulation of calcium ion transmembrane transport GO:1903169 28 0.804
visual perception GO:0007601 27 0.791
Human
divalent inorganic cation transport GO:0072511 158 0.775
regulation of transmembrane transporter activity GO:0022898 74 0.769
cation transport GO:0006812 331 0.765
regulation of metal ion transport GO:0010959 120 0.743
Human
regulation of ion transmembrane transporter activity GO:0032412 72 0.734
regulation of cation channel activity GO:2001257 33 0.716
regulation of cyclase activity GO:0031279 19 0.697
regulation of transporter activity GO:0032409 82 0.693
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.692
positive regulation of camp biosynthetic process GO:0030819 35 0.687
negative regulation of ion transmembrane transport GO:0034766 26 0.685
cyclic nucleotide metabolic process GO:0009187 82 0.668
transmembrane transport GO:0055085 399 0.650
positive regulation of adenylate cyclase activity GO:0045762 12 0.629
positive regulation of cyclase activity GO:0031281 13 0.582
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.572
regulation of adenylate cyclase activity GO:0045761 17 0.571
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.569
negative regulation of ion transport GO:0043271 39 0.560
regulation of ion transport GO:0043269 189 0.541
cyclic nucleotide biosynthetic process GO:0009190 61 0.539
system process GO:0003008 349 0.497
Human Zebrafish
regulation of protein localization GO:0032880 296 0.477
negative regulation of transmembrane transport GO:0034763 29 0.450
regulation of camp metabolic process GO:0030814 52 0.428
regulation of camp biosynthetic process GO:0030817 45 0.412
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.403
negative regulation of rho gtpase activity GO:0034259 4 0.393
inorganic ion transmembrane transport GO:0098660 231 0.389
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.381
inorganic cation transmembrane transport GO:0098662 194 0.379
cation transmembrane transport GO:0098655 238 0.378
camp biosynthetic process GO:0006171 47 0.375
regulation of lyase activity GO:0051339 23 0.365
g protein coupled receptor signaling pathway GO:0007186 207 0.365
ribonucleotide biosynthetic process GO:0009260 81 0.364
regulation of cytoplasmic transport GO:1903649 149 0.350
nucleoside phosphate biosynthetic process GO:1901293 109 0.347
regulation of voltage gated calcium channel activity GO:1901385 7 0.333
negative regulation of transporter activity GO:0032410 25 0.331
negative regulation of transport GO:0051051 176 0.298
positive regulation of ruffle assembly GO:1900029 4 0.292
negative regulation of calcium ion transport GO:0051926 19 0.277
negative regulation of protein transport GO:0051224 75 0.273
positive regulation of ion transport GO:0043270 87 0.270
Human
protein import GO:0017038 130 0.270
protein import into nucleus GO:0006606 104 0.239
purine ribonucleotide biosynthetic process GO:0009152 79 0.235
positive regulation of camp metabolic process GO:0030816 41 0.233
regulation of intracellular transport GO:0032386 195 0.231
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.228
cell communication by electrical coupling GO:0010644 5 0.222
cellular ion homeostasis GO:0006873 168 0.215
regulation of cell communication by electrical coupling GO:0010649 3 0.211
locomotory behavior GO:0007626 1 0.210
sensory perception GO:0007600 103 0.208
Human
regulation of locomotion GO:0040012 329 0.206
regulation of establishment of protein localization GO:0070201 242 0.205
regulation of heart contraction GO:0008016 50 0.200
Human Zebrafish
purine nucleotide biosynthetic process GO:0006164 84 0.195
regulation of protein localization to nucleus GO:1900180 85 0.192
neurological system process GO:0050877 163 0.188
Human
negative regulation of calcium ion transmembrane transport GO:1903170 11 0.180
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.176
camp metabolic process GO:0046058 61 0.174
regulation of cellular component movement GO:0051270 334 0.174
negative regulation of cation channel activity GO:2001258 12 0.171
calcium ion homeostasis GO:0055074 122 0.166
regulation of nucleotide biosynthetic process GO:0030808 50 0.164
cation homeostasis GO:0055080 189 0.159
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.158
cellular homeostasis GO:0019725 196 0.156
detection of stimulus GO:0051606 85 0.155
Human
single organism cellular localization GO:1902580 332 0.153
regulation of blood circulation GO:1903522 59 0.152
Human Zebrafish
cardiac muscle contraction GO:0060048 34 0.151
regulation of cardiac muscle contraction GO:0055117 33 0.149
protein targeting to nucleus GO:0044744 104 0.148
establishment of protein localization to organelle GO:0072594 172 0.148
positive regulation of transport GO:0051050 336 0.142
Human
regulation of protein import into nucleus GO:0042306 78 0.139
regulation of immune response GO:0050776 201 0.138
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.135
secretion GO:0046903 254 0.131
negative regulation of protein import into nucleus GO:0042308 30 0.130
nuclear transport GO:0051169 179 0.128
female gamete generation GO:0007292 2 0.126
regulation of nucleotide metabolic process GO:0006140 269 0.125
negative regulation of calcium ion transmembrane transporter activity GO:1901020 11 0.120
regulation of secretion GO:0051046 194 0.117
positive regulation of dna replication GO:0045740 35 0.117
regulation of calcium ion transport GO:0051924 79 0.115
Human
cellular calcium ion homeostasis GO:0006874 117 0.113
anatomical structure formation involved in morphogenesis GO:0048646 284 0.112
protein localization to organelle GO:0033365 280 0.112
protein targeting GO:0006605 187 0.111
positive regulation of cellular component movement GO:0051272 181 0.110
nuclear import GO:0051170 106 0.107
positive regulation of kinase activity GO:0033674 204 0.104
regulation of protein transport GO:0051223 213 0.103
regulation of nucleocytoplasmic transport GO:0046822 98 0.101
cellular potassium ion transport GO:0071804 60 0.100
regulation of protein targeting GO:1903533 91 0.098
positive regulation of hydrolase activity GO:0051345 331 0.096
intracellular protein transport GO:0006886 270 0.095
protein localization to nucleus GO:0034504 136 0.095
muscle system process GO:0003012 81 0.095
Human
metal ion homeostasis GO:0055065 169 0.094
regulation of intracellular protein transport GO:0033157 123 0.094
negative regulation of intracellular protein transport GO:0090317 42 0.094
determination of adult lifespan GO:0008340 2 0.091
regulation of cell migration GO:0030334 289 0.091
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.090
hemopoiesis GO:0030097 180 0.089
cyclic purine nucleotide metabolic process GO:0052652 60 0.089
cardiac muscle cell contraction GO:0086003 4 0.088
positive regulation of protein kinase activity GO:0045860 190 0.086
positive regulation of nucleoside metabolic process GO:0045979 186 0.086
positive regulation of developmental process GO:0051094 314 0.086
regulation of defense response GO:0031347 154 0.082
ribonucleotide catabolic process GO:0009261 405 0.081
positive regulation of dna metabolic process GO:0051054 73 0.081
membrane raft localization GO:0051665 1 0.081
mitotic cell cycle phase transition GO:0044772 162 0.080
cardiovascular system development GO:0072358 262 0.080
Zebrafish
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.079
positive regulation of cellular catabolic process GO:0031331 284 0.079
regulation of purine nucleotide metabolic process GO:1900542 264 0.078
blood circulation GO:0008015 113 0.077
Human Zebrafish
exocytosis GO:0006887 71 0.077
positive regulation of transferase activity GO:0051347 227 0.077
organophosphate biosynthetic process GO:0090407 163 0.076
regulation of kinase activity GO:0043549 314 0.075
regulation of rho protein signal transduction GO:0035023 79 0.075
organophosphate catabolic process GO:0046434 430 0.074
regulation of secretion by cell GO:1903530 177 0.074
negative regulation of intracellular transport GO:0032387 60 0.074
ribose phosphate biosynthetic process GO:0046390 82 0.072
regulation of cell cycle process GO:0010564 266 0.072
divalent metal ion transport GO:0070838 152 0.072
regulation of stress activated mapk cascade GO:0032872 84 0.071
nucleotide biosynthetic process GO:0009165 109 0.071
positive regulation of cellular component biogenesis GO:0044089 158 0.070
cell growth GO:0016049 160 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.070
purine ribonucleoside catabolic process GO:0046130 398 0.070
negative regulation of intracellular signal transduction GO:1902532 183 0.069
purine nucleotide catabolic process GO:0006195 405 0.069
stress activated protein kinase signaling cascade GO:0031098 94 0.068
ras protein signal transduction GO:0007265 73 0.068
organonitrogen compound biosynthetic process GO:1901566 200 0.068
positive regulation of phosphorylation GO:0042327 394 0.067
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.066
blood vessel development GO:0001568 172 0.066
growth GO:0040007 202 0.065
regulation of actin filament based process GO:0032970 141 0.064
regulation of angiogenesis GO:0045765 92 0.064
cell cycle phase transition GO:0044770 173 0.063
rho protein signal transduction GO:0007266 26 0.063
cell morphogenesis GO:0000902 296 0.061
negative regulation of protein localization to nucleus GO:1900181 34 0.061
purine ribonucleoside metabolic process GO:0046128 437 0.060
mapk cascade GO:0000165 288 0.060
cellular metal ion homeostasis GO:0006875 146 0.060
enzyme linked receptor protein signaling pathway GO:0007167 303 0.060
nucleoside triphosphate metabolic process GO:0009141 422 0.060
circadian behavior GO:0048512 2 0.059
regulation of gtp catabolic process GO:0033124 180 0.059
signal transduction by phosphorylation GO:0023014 297 0.057
neurotransmitter secretion GO:0007269 4 0.057
response to other organism GO:0051707 261 0.056
striated muscle contraction GO:0006941 52 0.055
cellular chemical homeostasis GO:0055082 180 0.055
regulation of heart rate GO:0002027 38 0.055
Human
positive regulation of map kinase activity GO:0043406 80 0.055
regulation of cell motility GO:2000145 299 0.054
negative regulation of immune system process GO:0002683 136 0.054
mating GO:0007618 1 0.054
cell cycle arrest GO:0007050 71 0.053
angiogenesis GO:0001525 147 0.051
positive regulation of nucleotide catabolic process GO:0030813 185 0.051
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.050
regulation of cell projection organization GO:0031344 107 0.050
regulation of cell morphogenesis GO:0022604 153 0.049
regulation of nucleotide catabolic process GO:0030811 205 0.049
regulation of cellular response to stress GO:0080135 244 0.049
positive regulation of synaptic transmission GO:0050806 4 0.049
cellular amine metabolic process GO:0044106 41 0.048
osteoblast differentiation GO:0001649 92 0.048
cell projection assembly GO:0030031 126 0.048
response to biotic stimulus GO:0009607 276 0.048
negative regulation of hydrolase activity GO:0051346 182 0.047
dna replication GO:0006260 116 0.047
positive regulation of catabolic process GO:0009896 310 0.047
positive regulation of cellular component organization GO:0051130 376 0.047
gamma aminobutyric acid signaling pathway GO:0007214 3 0.046
regulation of cell cycle GO:0051726 393 0.046
regulation of mitotic cell cycle phase transition GO:1901990 118 0.046
regulation of dna metabolic process GO:0051052 153 0.046
glycosyl compound catabolic process GO:1901658 413 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
cellular response to external stimulus GO:0071496 111 0.045
regulation of muscle system process GO:0090257 53 0.045
negative regulation of cytoplasmic transport GO:1903650 46 0.045
regulation of epithelial cell proliferation GO:0050678 113 0.045
negative regulation of apoptotic process GO:0043066 316 0.044
head development GO:0060322 108 0.044
response to external biotic stimulus GO:0043207 261 0.044
leukocyte differentiation GO:0002521 98 0.044
positive regulation of cellular amine metabolic process GO:0033240 7 0.044
neuromuscular junction development GO:0007528 3 0.043
regulation of exocytosis GO:0017157 46 0.043
positive regulation of gtp catabolic process GO:0033126 166 0.043
regulation of transcription by galactose GO:0000409 1 0.043
positive regulation of lyase activity GO:0051349 16 0.043
purine containing compound catabolic process GO:0072523 411 0.043
actin cytoskeleton organization GO:0030036 207 0.043
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.042
regulation of response to wounding GO:1903034 101 0.042
regulation of neurotransmitter secretion GO:0046928 3 0.041
positive regulation of protein phosphorylation GO:0001934 313 0.041
regulation of jnk cascade GO:0046328 73 0.041
negative regulation of sequestering of calcium ion GO:0051283 41 0.041
regulation of small gtpase mediated signal transduction GO:0051056 156 0.041
cell aging GO:0007569 52 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
regulation of nucleoside metabolic process GO:0009118 209 0.040
positive regulation of ras gtpase activity GO:0032320 117 0.040
gtp catabolic process GO:0006184 237 0.040
negative regulation of cell cycle phase transition GO:1901988 89 0.040
negative regulation of catalytic activity GO:0043086 335 0.040
activation of adenylate cyclase activity GO:0007190 5 0.039
multicellular organismal aging GO:0010259 3 0.039
cytosolic calcium ion homeostasis GO:0051480 89 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.039
regulation of wound healing GO:0061041 56 0.038
jnk cascade GO:0007254 80 0.038
positive regulation of angiogenesis GO:0045766 51 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
regulation of gtpase activity GO:0043087 180 0.037
regulation of striated muscle contraction GO:0006942 37 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
vesicle mediated transport GO:0016192 371 0.037
metencephalon development GO:0022037 2 0.036
negative regulation of cell cycle GO:0045786 193 0.036
positive regulation of cell motility GO:2000147 177 0.036
potassium ion transport GO:0006813 62 0.036
cytoplasmic transport GO:0016482 379 0.036
rhythmic behavior GO:0007622 2 0.036
sequestering of calcium ion GO:0051208 17 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
positive regulation of response to wounding GO:1903036 28 0.035
oogenesis GO:0048477 2 0.035
regulation of actin cytoskeleton organization GO:0032956 116 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
cellular divalent inorganic cation homeostasis GO:0072503 128 0.035
cell projection organization GO:0030030 252 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
cytokinesis GO:0000910 96 0.035
positive regulation of cell migration GO:0030335 172 0.035
amine metabolic process GO:0009308 44 0.034
positive regulation of cyclic nucleotide phosphodiesterase activity GO:0051343 4 0.034
hindbrain development GO:0030902 3 0.034
release of sequestered calcium ion into cytosol GO:0051209 41 0.034
mitotic cell cycle checkpoint GO:0007093 68 0.034
cellular response to endogenous stimulus GO:0071495 336 0.034
regulation of vasculature development GO:1901342 97 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
positive regulation of organelle organization GO:0010638 195 0.033
positive regulation of locomotion GO:0040017 186 0.033
cellular ketone metabolic process GO:0042180 80 0.033
cellular component morphogenesis GO:0032989 314 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
negative regulation of catabolic process GO:0009895 104 0.033
regulation of ion homeostasis GO:2000021 73 0.032
positive regulation of jnk cascade GO:0046330 52 0.032
regulation of synaptic plasticity GO:0048167 3 0.032
regulation of dna replication GO:0006275 68 0.032
cellular response to nutrient GO:0031670 12 0.031
maintenance of location GO:0051235 112 0.031
detection of calcium ion GO:0005513 8 0.031
actin filament based process GO:0030029 224 0.031
positive regulation of wound healing GO:0090303 20 0.031
defense response GO:0006952 315 0.031
regulation of homeostatic process GO:0032844 121 0.031
actin filament based movement GO:0030048 17 0.031
negative regulation of cell death GO:0060548 345 0.031
regulation of potassium ion transmembrane transport GO:1901379 20 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.030
single organism membrane organization GO:0044802 268 0.030
nucleotide catabolic process GO:0009166 408 0.030
regulation of ryanodine sensitive calcium release channel activity GO:0060314 12 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
neuron death GO:0070997 65 0.030
innate immune response GO:0045087 178 0.030
regulation of mapk cascade GO:0043408 262 0.030
cerebellum development GO:0021549 2 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.030
immune response GO:0006955 307 0.030
negative regulation of defense response GO:0031348 47 0.029
regulation of protein kinase activity GO:0045859 289 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
detection of chemical stimulus GO:0009593 55 0.029
nerve development GO:0021675 4 0.029
circulatory system development GO:0072359 262 0.028
Zebrafish
action potential GO:0001508 34 0.028
Human
regulation of ras protein signal transduction GO:0046578 155 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
muscle contraction GO:0006936 73 0.028
Human
neural nucleus development GO:0048857 47 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
regulation of ruffle assembly GO:1900027 8 0.028
cellular senescence GO:0090398 34 0.028
response to oxygen containing compound GO:1901700 369 0.028
carbohydrate metabolic process GO:0005975 207 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
sensory perception of pain GO:0019233 4 0.027
guanosine containing compound metabolic process GO:1901068 244 0.027
second messenger mediated signaling GO:0019932 78 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.027
positive regulation of mapk cascade GO:0043410 190 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
regulation of transferase activity GO:0051338 355 0.027
startle response GO:0001964 3 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
sequestering of metal ion GO:0051238 24 0.027
epithelial cell proliferation GO:0050673 128 0.026
negative regulation of cell cycle process GO:0010948 121 0.026
regulation of phosphatase activity GO:0010921 81 0.026
regulation of muscle contraction GO:0006937 45 0.026
response to inorganic substance GO:0010035 127 0.026
regulation of neuron death GO:1901214 56 0.026
regulation of hormone levels GO:0010817 125 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
protein kinase b signaling GO:0043491 69 0.025
cardiac conduction GO:0061337 23 0.025
Human
small gtpase mediated signal transduction GO:0007264 78 0.025
positive regulation of axon extension GO:0045773 4 0.024
multicellular organismal response to stress GO:0033555 1 0.024
negative regulation of phosphorylation GO:0042326 174 0.024
neurogenesis GO:0022008 169 0.024
ossification GO:0001503 121 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
cellular response to nutrient levels GO:0031669 69 0.024
nucleoside catabolic process GO:0009164 408 0.024
regulation of dephosphorylation GO:0035303 96 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
dephosphorylation GO:0016311 209 0.024
circulatory system process GO:0003013 113 0.023
Human Zebrafish
memory GO:0007613 3 0.023
positive regulation of calcium ion transport GO:0051928 51 0.023
Human
behavior GO:0007610 112 0.023
chemical homeostasis GO:0048878 306 0.023
central nervous system development GO:0007417 123 0.023
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.023
response to drug GO:0042493 81 0.023
mirna metabolic process GO:0010586 10 0.023
protein oligomerization GO:0051259 173 0.023
regulation of growth GO:0040008 165 0.022
negative regulation of cellular catabolic process GO:0031330 83 0.022
regulation of proteolysis GO:0030162 293 0.022
compound eye development GO:0048749 1 0.022
regulation of ras gtpase activity GO:0032318 128 0.022
post embryonic development GO:0009791 2 0.022
spermatid differentiation GO:0048515 4 0.022
regulation of cell division GO:0051302 116 0.022
blood vessel morphogenesis GO:0048514 162 0.022
purine containing compound biosynthetic process GO:0072522 88 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.021
endoplasmic reticulum to cytosol transport GO:1903513 13 0.021
regulation of cell cycle phase transition GO:1901987 126 0.021
regulation of innate immune response GO:0045088 97 0.021
actin mediated cell contraction GO:0070252 12 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
defense response to other organism GO:0098542 129 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
cell adhesion GO:0007155 325 0.021
positive regulation of transcription by galactose GO:0000411 1 0.021
positive regulation of epithelial cell proliferation GO:0050679 65 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.021
segmentation GO:0035282 4 0.021
synaptic transmission GO:0007268 61 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
protein processing GO:0016485 226 0.020
negative regulation of immune response GO:0050777 40 0.020
positive regulation of immune system process GO:0002684 283 0.020
gtp metabolic process GO:0046039 239 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
calcium ion transport into cytosol GO:0060402 48 0.020
positive regulation of cytoskeleton organization GO:0051495 83 0.020
spermatid development GO:0007286 4 0.020
endocytosis GO:0006897 159 0.020
response to radiation GO:0009314 151 0.020
Human
regulation of rho gtpase activity GO:0032319 66 0.020
cell division GO:0051301 168 0.019
mitotic cell cycle GO:0000278 326 0.019
mitotic cell cycle process GO:1903047 286 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 4 0.019
protein catabolic process GO:0030163 325 0.019
ion homeostasis GO:0050801 230 0.019
regulation of neuronal synaptic plasticity GO:0048168 1 0.019
reproductive process GO:0022414 106 0.019
oocyte differentiation GO:0009994 2 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
negative regulation of stress activated mapk cascade GO:0032873 19 0.018
peripheral nervous system development GO:0007422 2 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
positive regulation of transmembrane transport GO:0034764 41 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
negative regulation of nucleotide catabolic process GO:0030812 16 0.018
response to calcium ion GO:0051592 46 0.018
stress activated mapk cascade GO:0051403 93 0.018
cell development GO:0048468 328 0.018
response to disaccharide GO:0034285 1 0.017
regeneration GO:0031099 4 0.017
response to organonitrogen compound GO:0010243 156 0.017
immune system development GO:0002520 195 0.017
cellular lipid metabolic process GO:0044255 303 0.017
ncrna metabolic process GO:0034660 108 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
cell cycle checkpoint GO:0000075 117 0.017
endomembrane system organization GO:0010256 196 0.017
response to wounding GO:0009611 168 0.017
regulation of cyclic nucleotide phosphodiesterase activity GO:0051342 4 0.017
cellular response to extracellular stimulus GO:0031668 72 0.017
response to nutrient levels GO:0031667 81 0.017
positive regulation of actin cytoskeleton reorganization GO:2000251 9 0.017
membrane hyperpolarization GO:0060081 1 0.017
erk1 and erk2 cascade GO:0070371 104 0.016
cellular cation homeostasis GO:0030003 163 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
positive regulation of cell projection organization GO:0031346 64 0.016
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.016
apoptotic signaling pathway GO:0097190 268 0.016
sulfur compound metabolic process GO:0006790 101 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
response to organic cyclic compound GO:0014070 204 0.016
monosaccharide metabolic process GO:0005996 74 0.016
regulation of cell adhesion GO:0030155 166 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.015
cell part morphogenesis GO:0032990 137 0.015
defense response to gram negative bacterium GO:0050829 14 0.015
spinal cord development GO:0021510 4 0.015
response to bacterium GO:0009617 144 0.015
cell type specific apoptotic process GO:0097285 125 0.015
sensory perception of light stimulus GO:0050953 35 0.015
Human
regulation of cell growth GO:0001558 135 0.015
regulation of cell projection assembly GO:0060491 47 0.015
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
biological adhesion GO:0022610 331 0.015
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.015
skeletal system development GO:0001501 79 0.015
Zebrafish
replicative cell aging GO:0001302 3 0.015
regulation of filopodium assembly GO:0051489 13 0.015
adult locomotory behavior GO:0008344 1 0.014
negative regulation of synaptic transmission GO:0050805 2 0.014
secretion by cell GO:0032940 226 0.014
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.014

CACNA1C disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.050
Human
cardiovascular system disease DOID:1287 106 0.030
central nervous system disease DOID:331 186 0.028
Human
nervous system disease DOID:863 431 0.028
Human
myopathy DOID:423 104 0.026
Human
muscular disease DOID:0080000 114 0.026
Human
muscle tissue disease DOID:66 113 0.026
Human
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.021
disease of metabolism DOID:0014667 295 0.020
Human
neurodegenerative disease DOID:1289 102 0.019
Human
sensory system disease DOID:0050155 203 0.016
Human
brain disease DOID:936 73 0.015
Human
heart disease DOID:114 68 0.014