|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
1.000
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
1 |
1.000
|
Mouse |
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
3 |
1.000
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
3 |
1.000
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
5 |
0.999
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.999
|
Mouse |
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.998
|
Mouse |
|
|
t cell lineage commitment
|
GO:0002360 |
1 |
0.998
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.997
|
Mouse |
|
|
t cell selection
|
GO:0045058 |
4 |
0.997
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.996
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.995
|
Mouse |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.995
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.994
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.994
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
5 |
0.992
|
Mouse |
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.991
|
Mouse |
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.991
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
7 |
0.985
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.980
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.979
|
Mouse |
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.977
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.975
|
Mouse |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.973
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.972
|
Mouse |
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.970
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.966
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.963
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.961
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.958
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.950
|
Mouse |
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.948
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.943
|
Mouse |
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.941
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.934
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.928
|
Mouse |
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.924
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.919
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.918
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
7 |
0.912
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.910
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.909
|
Mouse |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.906
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.905
|
Mouse |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
6 |
0.903
|
Mouse |
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
4 |
0.900
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.896
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.895
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.891
|
Mouse |
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.889
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.888
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.882
|
Mouse |
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.882
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.881
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.881
|
Mouse |
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
1 |
0.878
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.873
|
Mouse |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.873
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.871
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.871
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.870
|
Mouse |
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.870
|
Mouse |
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
3 |
0.869
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.868
|
Mouse |
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.866
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.865
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.865
|
Mouse |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.860
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.860
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.857
|
Mouse |
|
|
sex determination
|
GO:0007530 |
3 |
0.856
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.849
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
1 |
0.849
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.849
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.847
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.840
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.837
|
Mouse |
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
8 |
0.831
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.827
|
Mouse |
|
|
b cell mediated immunity
|
GO:0019724 |
10 |
0.822
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.819
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.815
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
19 |
0.803
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.802
|
Rat |
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.802
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.802
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.801
|
|
|
|
memory
|
GO:0007613 |
3 |
0.799
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.798
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.796
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.794
|
Mouse |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.792
|
Mouse |
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.792
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.792
|
Mouse |
|
|
regulation of dna recombination
|
GO:0000018 |
23 |
0.791
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.786
|
Mouse |
|
|
segmentation
|
GO:0035282 |
4 |
0.785
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.785
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.783
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.778
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.772
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.771
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.770
|
Mouse |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.767
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.764
|
Mouse |
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.760
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.760
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.759
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.759
|
Mouse |
|
|
positive regulation of dna recombination
|
GO:0045911 |
3 |
0.759
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.755
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.749
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.747
|
Mouse |
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.741
|
Mouse |
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.740
|
Mouse |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.735
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.733
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.731
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.727
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.720
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.705
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.705
|
Mouse |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.703
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.701
|
Rat |
|
|
long term memory
|
GO:0007616 |
2 |
0.696
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.693
|
Mouse |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.692
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
4 |
0.682
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.680
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.666
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.665
|
Mouse |
|
|
renal system development
|
GO:0072001 |
63 |
0.660
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.659
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.645
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.632
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.630
|
Mouse |
|
|
t helper 1 type immune response
|
GO:0042088 |
8 |
0.623
|
Mouse |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.619
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.616
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.616
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.615
|
|
|
|
negative regulation of osteoclast differentiation
|
GO:0045671 |
8 |
0.613
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.612
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.610
|
Mouse |
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.607
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.595
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.593
|
|
|
|
cell dedifferentiation
|
GO:0043697 |
1 |
0.588
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.587
|
Rat |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
8 |
0.581
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.579
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.572
|
Mouse |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.571
|
Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.559
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.553
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.553
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.549
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
4 |
0.548
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.538
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.534
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.533
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.531
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.528
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.526
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.526
|
Mouse |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.521
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
3 |
0.519
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.514
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.510
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.507
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.498
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.489
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.485
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
178 |
0.482
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.482
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.477
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.468
|
Mouse |
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.465
|
Mouse |
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.465
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
3 |
0.464
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.463
|
Mouse |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.458
|
Mouse |
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.456
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.456
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.454
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.452
|
Mouse |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.450
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.442
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
6 |
0.433
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.428
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.426
|
Mouse |
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.424
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.424
|
Mouse |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.420
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.416
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.415
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.415
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.411
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
4 |
0.406
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.401
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.400
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.398
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.398
|
|
|
|
positive regulation of myoblast fusion
|
GO:1901741 |
1 |
0.393
|
Mouse |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.392
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.386
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.385
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
5 |
0.382
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.382
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.378
|
|
|
|
positive t cell selection
|
GO:0043368 |
2 |
0.375
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.375
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.368
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.365
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.363
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.362
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.362
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.361
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
28 |
0.353
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.352
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.352
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.344
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.338
|
Rat |
|
|
secretion
|
GO:0046903 |
254 |
0.337
|
Mouse |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.328
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.326
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.325
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.325
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.323
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.321
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.319
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.319
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.319
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.318
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.317
|
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.311
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.309
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.305
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.300
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.299
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.294
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.292
|
Mouse |
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.286
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.286
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.284
|
Mouse |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.276
|
Mouse |
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.271
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.270
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.267
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.265
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.260
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.260
|
Mouse |
|
|
somatic cell dna recombination
|
GO:0016444 |
6 |
0.258
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
10 |
0.257
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.256
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.256
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.254
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.251
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.249
|
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
4 |
0.248
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.247
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.242
|
Mouse |
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
8 |
0.242
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.239
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.238
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.233
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.229
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.227
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
13 |
0.226
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.226
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.222
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.222
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.221
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.220
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.219
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.218
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.217
|
Mouse |
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.217
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.216
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
2 |
0.215
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.213
|
Mouse |
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
5 |
0.211
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.210
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.210
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.206
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.205
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.202
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.202
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.201
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.199
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.196
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.195
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.195
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.195
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.195
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.195
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.194
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.192
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.191
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.190
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.189
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.182
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.179
|
Mouse |
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.174
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.169
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.169
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.167
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.166
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.166
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.165
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.163
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.163
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.161
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.160
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.159
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.158
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.156
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.156
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.153
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.153
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.152
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.152
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.151
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.151
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.150
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
15 |
0.150
|
Mouse |
|
|
leukocyte degranulation
|
GO:0043299 |
11 |
0.148
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.148
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.147
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.146
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.144
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.142
|
Mouse |
|
|
negative regulation of monocyte differentiation
|
GO:0045656 |
3 |
0.142
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.138
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.138
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
11 |
0.138
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.138
|
Mouse |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.136
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.136
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.135
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.133
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.132
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.131
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.131
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.129
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.127
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.126
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.125
|
|
|
|
positive regulation of mhc class ii biosynthetic process
|
GO:0045348 |
3 |
0.124
|
|
|
|
response to interleukin 4
|
GO:0070670 |
7 |
0.122
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.121
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.119
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.119
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.118
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.117
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.117
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
2 |
0.117
|
Mouse |
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.115
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.115
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.114
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.114
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.111
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.110
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.110
|
|
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.108
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.108
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.107
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.105
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.105
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.105
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.104
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.104
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.104
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.103
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
20 |
0.103
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.102
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.102
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.101
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.101
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.101
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.101
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.100
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.100
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.100
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.099
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.098
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.098
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.097
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.097
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.095
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.094
|
|
|
|
interleukin 13 production
|
GO:0032616 |
7 |
0.093
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.091
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.088
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.087
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.087
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.086
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.085
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.085
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.085
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.085
|
Mouse |
|
|
organ or tissue specific immune response
|
GO:0002251 |
22 |
0.084
|
|
|
|
activated t cell proliferation
|
GO:0050798 |
13 |
0.083
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.082
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
11 |
0.082
|
Mouse |
|
|
mammary gland development
|
GO:0030879 |
17 |
0.081
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.081
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.080
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.079
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.079
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.079
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.079
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
5 |
0.078
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.078
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.075
|
Mouse |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.074
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.074
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.074
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.073
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.072
|
Mouse |
|
|
tube development
|
GO:0035295 |
125 |
0.072
|
|
|
|
mucosal immune response
|
GO:0002385 |
21 |
0.071
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.071
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
7 |
0.070
|
|
|
|
response to interferon beta
|
GO:0035456 |
11 |
0.070
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.070
|
Rat |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.070
|
|
|
|
negative regulation of bone resorption
|
GO:0045779 |
2 |
0.070
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.069
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.069
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.068
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
3 |
0.068
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.067
|
Mouse |
|
|
t cell cytokine production
|
GO:0002369 |
12 |
0.067
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.067
|
Mouse |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.066
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.066
|
|
|
|
cellular response to reactive nitrogen species
|
GO:1902170 |
2 |
0.066
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.065
|
Mouse |
|
|
taxis
|
GO:0042330 |
157 |
0.064
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.064
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.063
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.061
|
Mouse |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.061
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.060
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.059
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.058
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.058
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.057
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.057
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.056
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.056
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.056
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
2 |
0.056
|
Mouse |
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.055
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.055
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.055
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.054
|
|
|
|
immunoglobulin production
|
GO:0002377 |
12 |
0.054
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.053
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.053
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.053
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
2 |
0.052
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.051
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
7 |
0.051
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.051
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.050
|
|
|
|
negative regulation of response to biotic stimulus
|
GO:0002832 |
18 |
0.050
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.050
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.050
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.050
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.049
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.049
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.049
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.048
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.048
|
|
|
|
negative regulation of interleukin 6 biosynthetic process
|
GO:0045409 |
3 |
0.048
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.048
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.047
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.046
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.046
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.046
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.045
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.045
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.044
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.044
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.044
|
Rat |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.044
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.043
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.043
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.043
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.042
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.042
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.042
|
|
