Homo sapiens

57 known processes

PQBP1

polyglutamine binding protein 1

(Aliases: SHS,MRXS3,MRXS8,MRX55,NPW38,RENS1)

PQBP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.331
nadh metabolic process GO:0006734 1 0.170
oogenesis GO:0048477 2 0.124
vesicle mediated transport GO:0016192 371 0.106
purine nucleoside triphosphate metabolic process GO:0009144 412 0.105
oxidation reduction process GO:0055114 396 0.090
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.074
purine ribonucleoside metabolic process GO:0046128 437 0.073
reproductive system development GO:0061458 56 0.072
cell division GO:0051301 168 0.072
posttranscriptional regulation of gene expression GO:0010608 213 0.072
embryo development GO:0009790 123 0.072
small gtpase mediated signal transduction GO:0007264 78 0.066
response to other organism GO:0051707 261 0.063
system process GO:0003008 349 0.063
Fly
membrane fusion GO:0061025 43 0.060
sex differentiation GO:0007548 45 0.058
regulation of nucleotide metabolic process GO:0006140 269 0.057
cellular macromolecule catabolic process GO:0044265 380 0.055
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.055
positive regulation of apoptotic process GO:0043065 246 0.055
oocyte development GO:0048599 1 0.054
ncrna metabolic process GO:0034660 108 0.054
regulation of meiotic cell cycle GO:0051445 4 0.052
nucleoside monophosphate metabolic process GO:0009123 191 0.052
female gamete generation GO:0007292 2 0.050
single organism reproductive process GO:0044702 98 0.049
reproductive structure development GO:0048608 55 0.045
lipid metabolic process GO:0006629 381 0.045
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
cellular homeostasis GO:0019725 196 0.043
nucleoside triphosphate metabolic process GO:0009141 422 0.043
regulation of membrane potential GO:0042391 95 0.041
isocitrate metabolic process GO:0006102 1 0.041
chemical homeostasis GO:0048878 306 0.038
cell activation GO:0001775 213 0.038
muscle cell cellular homeostasis GO:0046716 3 0.035
single organism membrane fusion GO:0044801 37 0.033
immune system development GO:0002520 195 0.033
cellular metal ion homeostasis GO:0006875 146 0.033
growth GO:0040007 202 0.032
regulation of cell differentiation GO:0045595 393 0.031
Mouse
positive regulation of immune system process GO:0002684 283 0.031
development of primary sexual characteristics GO:0045137 35 0.031
response to biotic stimulus GO:0009607 276 0.031
translation GO:0006412 132 0.030
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
response to cytokine GO:0034097 232 0.029
establishment of nucleus localization GO:0040023 1 0.028
developmental process involved in reproduction GO:0003006 66 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
chromatin modification GO:0016568 298 0.027
regulation of cell division GO:0051302 116 0.026
covalent chromatin modification GO:0016569 254 0.026
coenzyme metabolic process GO:0006732 65 0.025
positive regulation of dna metabolic process GO:0051054 73 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
cellular macromolecular complex assembly GO:0034622 324 0.024
alternative mrna splicing via spliceosome GO:0000380 27 0.023
organelle fission GO:0048285 149 0.023
hemopoiesis GO:0030097 180 0.022
positive regulation of cell death GO:0010942 263 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
reproductive process GO:0022414 106 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
defense response GO:0006952 315 0.022
cellular protein complex assembly GO:0043623 188 0.022
positive regulation of cellular component organization GO:0051130 376 0.021
cofactor metabolic process GO:0051186 87 0.021
histone modification GO:0016570 251 0.021
immune response GO:0006955 307 0.021
regulation of dna metabolic process GO:0051052 153 0.021
response to external biotic stimulus GO:0043207 261 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
blastocyst development GO:0001824 3 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of cellular component biogenesis GO:0044087 281 0.019
nucleotide catabolic process GO:0009166 408 0.019
regulation of protein complex assembly GO:0043254 147 0.019
positive regulation of transport GO:0051050 336 0.019
reproduction GO:0000003 63 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
cellular amine metabolic process GO:0044106 41 0.019
immune effector process GO:0002252 159 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
nucleus localization GO:0051647 1 0.019
positive regulation of cellular component biogenesis GO:0044089 158 0.019
endocytosis GO:0006897 159 0.019
regulation of nuclear division GO:0051783 65 0.018
2 oxoglutarate metabolic process GO:0006103 4 0.018
cell development GO:0048468 328 0.018
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
negative regulation of developmental process GO:0051093 247 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
tube development GO:0035295 125 0.018
protein maturation GO:0051604 233 0.017
chromatin organization GO:0006325 351 0.017
mitochondrion organization GO:0007005 156 0.017
regulation of intracellular transport GO:0032386 195 0.017
response to oxygen containing compound GO:1901700 369 0.017
cytokine production GO:0001816 247 0.017
generation of precursor metabolites and energy GO:0006091 68 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
central nervous system development GO:0007417 123 0.016
cytoplasmic transport GO:0016482 379 0.016
nuclear migration GO:0007097 1 0.016
mitotic nuclear division GO:0007067 119 0.016
regulation of protein transport GO:0051223 213 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
dna catabolic process GO:0006308 49 0.016
cellular ketone metabolic process GO:0042180 80 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
ncrna processing GO:0034470 83 0.016
purine nucleoside catabolic process GO:0006152 398 0.015
regulation of cellular response to stress GO:0080135 244 0.015
behavior GO:0007610 112 0.015
Fly
cellular component morphogenesis GO:0032989 314 0.015
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
cellular chemical homeostasis GO:0055082 180 0.015
establishment of organelle localization GO:0051656 59 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
mitochondrial transport GO:0006839 60 0.015
amine metabolic process GO:0009308 44 0.015
ossification GO:0001503 121 0.015
intracellular protein transport GO:0006886 270 0.015
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
ion homeostasis GO:0050801 230 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
multicellular organismal aging GO:0010259 3 0.014
cilium morphogenesis GO:0060271 75 0.014
regulation of cell cycle process GO:0010564 266 0.014
multi organism cellular process GO:0044764 156 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
metal ion homeostasis GO:0055065 169 0.014
gonad development GO:0008406 34 0.013
regulation of growth GO:0040008 165 0.013
cilium assembly GO:0042384 63 0.013
regulation of protein localization GO:0032880 296 0.013
nuclear division GO:0000280 128 0.013
chromosome segregation GO:0007059 114 0.013
regulation of feeding behavior GO:0060259 3 0.012
regulation of oxidoreductase activity GO:0051341 43 0.012
tricarboxylic acid metabolic process GO:0072350 4 0.012
membrane organization GO:0061024 292 0.012
protein import GO:0017038 130 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
divalent inorganic cation transport GO:0072511 158 0.012
negative regulation of cell death GO:0060548 345 0.012
epithelial cell proliferation GO:0050673 128 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
single organism membrane organization GO:0044802 268 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
energy derivation by oxidation of organic compounds GO:0015980 43 0.012
myeloid cell differentiation GO:0030099 117 0.012
apoptotic signaling pathway GO:0097190 268 0.012
protein targeting GO:0006605 187 0.012
negative regulation of cell cycle GO:0045786 193 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
lipid localization GO:0010876 106 0.011
Worm
positive regulation of immune response GO:0050778 159 0.011
cardiovascular system development GO:0072358 262 0.011
negative regulation of growth GO:0045926 97 0.011
regulation of behavior GO:0050795 82 0.011
epithelium development GO:0060429 227 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
protein polymerization GO:0051258 71 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
regulation of actin filament based process GO:0032970 141 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
secretion GO:0046903 254 0.011
cation homeostasis GO:0055080 189 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
regulation of mrna processing GO:0050684 48 0.011
single organism cellular localization GO:1902580 332 0.010
regulation of mitochondrion organization GO:0010821 54 0.010
osteoblast differentiation GO:0001649 92 0.010
transmembrane transport GO:0055085 399 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010

PQBP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.087
eye and adnexa disease DOID:1492 150 0.087
nervous system disease DOID:863 431 0.087
eye disease DOID:5614 149 0.087
retinal disease DOID:5679 118 0.087
disease of cellular proliferation DOID:14566 174 0.066
cancer DOID:162 167 0.024
organ system cancer DOID:0050686 164 0.024
retinal degeneration DOID:8466 89 0.020
retinitis pigmentosa DOID:10584 51 0.020
disease of mental health DOID:150 70 0.002
developmental disorder of mental health DOID:0060037 29 0.001
syndromic intellectual disability DOID:0050888 4 0.000
specific developmental disorder DOID:0060038 19 0.000
intellectual disability DOID:1059 13 0.000