Homo sapiens

20 known processes

TTC19

tetratricopeptide repeat domain 19

(Aliases: MGC138312,MGC19520,2010204O13Rik,FLJ20343)

TTC19 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.118
negative regulation of cellular protein metabolic process GO:0032269 353 0.091
cellular amino acid metabolic process GO:0006520 116 0.083
amine metabolic process GO:0009308 44 0.077
female gamete generation GO:0007292 2 0.072
regulation of transferase activity GO:0051338 355 0.070
cellular amine metabolic process GO:0044106 41 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.060
membrane organization GO:0061024 292 0.060
mapk cascade GO:0000165 288 0.060
system process GO:0003008 349 0.059
post embryonic development GO:0009791 2 0.056
ras protein signal transduction GO:0007265 73 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
negative regulation of protein metabolic process GO:0051248 391 0.051
regulation of cellular amine metabolic process GO:0033238 11 0.051
actin filament based process GO:0030029 224 0.051
multicellular organismal aging GO:0010259 3 0.050
small gtpase mediated signal transduction GO:0007264 78 0.050
positive regulation of organelle organization GO:0010638 195 0.047
oogenesis GO:0048477 2 0.047
negative regulation of phosphorylation GO:0042326 174 0.046
cellular response to dna damage stimulus GO:0006974 379 0.046
negative regulation of cellular amine metabolic process GO:0033239 3 0.045
negative regulation of protein modification process GO:0031400 200 0.045
negative regulation of ruffle assembly GO:1900028 3 0.045
regulation of mapk cascade GO:0043408 262 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.043
determination of adult lifespan GO:0008340 2 0.043
negative regulation of catalytic activity GO:0043086 335 0.042
ion homeostasis GO:0050801 230 0.042
cellular protein complex assembly GO:0043623 188 0.041
single organism membrane organization GO:0044802 268 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.040
signal transduction by phosphorylation GO:0023014 297 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
negative regulation of multicellular organismal process GO:0051241 317 0.038
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
cellular macromolecular complex assembly GO:0034622 324 0.037
neurological system process GO:0050877 163 0.037
memory GO:0007613 3 0.036
chemical homeostasis GO:0048878 306 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.033
transmembrane transport GO:0055085 399 0.033
cell development GO:0048468 328 0.033
regulation of kinase activity GO:0043549 314 0.032
cellular lipid metabolic process GO:0044255 303 0.032
inorganic ion transmembrane transport GO:0098660 231 0.031
positive regulation of transport GO:0051050 336 0.031
neuromuscular junction development GO:0007528 3 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
regulation of cytoskeleton organization GO:0051493 177 0.030
metal ion transport GO:0030001 272 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
immune response GO:0006955 307 0.029
cell morphogenesis GO:0000902 296 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.028
organophosphate catabolic process GO:0046434 430 0.028
protein localization to organelle GO:0033365 280 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
single organism cellular localization GO:1902580 332 0.027
regulation of actin cytoskeleton organization GO:0032956 116 0.027
ion transmembrane transport GO:0034220 338 0.027
cellular homeostasis GO:0019725 196 0.026
negative regulation of transferase activity GO:0051348 124 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
proteasomal protein catabolic process GO:0010498 176 0.026
dephosphorylation GO:0016311 209 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
regulation of actin filament based process GO:0032970 141 0.025
carbohydrate metabolic process GO:0005975 207 0.025
protein ubiquitination GO:0016567 314 0.025
negative regulation of cell death GO:0060548 345 0.025
spermatid development GO:0007286 4 0.025
cation transmembrane transport GO:0098655 238 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
regulation of protein complex assembly GO:0043254 147 0.024
cation transport GO:0006812 331 0.023
adult locomotory behavior GO:0008344 1 0.023
Fly
negative regulation of cellular component organization GO:0051129 235 0.023
cellular chemical homeostasis GO:0055082 180 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
regulation of protein kinase activity GO:0045859 289 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
regulation of cell differentiation GO:0045595 393 0.023
nucleotide catabolic process GO:0009166 408 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.022
maintenance of location GO:0051235 112 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
negative regulation of kinase activity GO:0033673 106 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
cellular component morphogenesis GO:0032989 314 0.022
cellular protein catabolic process GO:0044257 261 0.022
actin filament polymerization GO:0030041 45 0.022
intracellular protein transport GO:0006886 270 0.022
protein maturation GO:0051604 233 0.022
blastoderm segmentation GO:0007350 2 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
regulation of cell motility GO:2000145 299 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
negative regulation of protein kinase activity GO:0006469 98 0.021
locomotory behavior GO:0007626 1 0.021
Fly
lipid metabolic process GO:0006629 381 0.021
translation GO:0006412 132 0.020
biological adhesion GO:0022610 331 0.020
generation of neurons GO:0048699 152 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
cell projection organization GO:0030030 252 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
atp metabolic process GO:0046034 176 0.020
ameboidal type cell migration GO:0001667 135 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
cytoplasmic transport GO:0016482 379 0.020
regulation of growth GO:0040008 165 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
regulation of cellular component movement GO:0051270 334 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
nucleoside catabolic process GO:0009164 408 0.019
macromolecule deacylation GO:0098732 41 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
associative learning GO:0008306 1 0.019
response to growth factor GO:0070848 205 0.019
protein catabolic process GO:0030163 325 0.019
regulation of ras protein signal transduction GO:0046578 155 0.018
vesicle mediated transport GO:0016192 371 0.018
spermatid differentiation GO:0048515 4 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
segmentation GO:0035282 4 0.018
protein localization to membrane GO:0072657 160 0.018
oocyte development GO:0048599 1 0.018
regulation of cell migration GO:0030334 289 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
protein polymerization GO:0051258 71 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
mitotic cell cycle process GO:1903047 286 0.018
oocyte differentiation GO:0009994 2 0.018
mitotic cell cycle GO:0000278 326 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
innate immune response GO:0045087 178 0.017
blood vessel morphogenesis GO:0048514 162 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
actin filament bundle assembly GO:0051017 54 0.017
negative regulation of phosphatase activity GO:0010923 61 0.017
response to biotic stimulus GO:0009607 276 0.017
oxidation reduction process GO:0055114 396 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
actin cytoskeleton organization GO:0030036 207 0.017
regulation of defense response GO:0031347 154 0.017
regulation of actin polymerization or depolymerization GO:0008064 56 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
intracellular mrna localization GO:0008298 1 0.016
compound eye development GO:0048749 1 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
nitrogen compound transport GO:0071705 191 0.016
cellular cation homeostasis GO:0030003 163 0.016
neurogenesis GO:0022008 169 0.016
negative regulation of cell migration GO:0030336 102 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
microtubule based process GO:0007017 210 0.016
lipid localization GO:0010876 106 0.016
positive regulation of actin filament bundle assembly GO:0032233 25 0.016
regulation of anatomical structure size GO:0090066 101 0.016
small molecule biosynthetic process GO:0044283 157 0.016
positive regulation of signal transduction by p53 class mediator GO:1901798 10 0.016
defense response GO:0006952 315 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
epithelial cell migration GO:0010631 119 0.015
positive regulation of cell death GO:0010942 263 0.015
regulation of response to dna damage stimulus GO:2001020 94 0.015
regulation of dephosphorylation GO:0035303 96 0.015
actin polymerization or depolymerization GO:0008154 56 0.015
response to external biotic stimulus GO:0043207 261 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
nervous system development GO:0007399 293 0.015
cofactor metabolic process GO:0051186 87 0.015
chromatin modification GO:0016568 298 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
response to abiotic stimulus GO:0009628 336 0.015
Fly
tissue migration GO:0090130 119 0.015
limbic system development GO:0021761 3 0.015
cation homeostasis GO:0055080 189 0.015
rho protein signal transduction GO:0007266 26 0.015
protein deacetylation GO:0006476 38 0.015
secretion by cell GO:0032940 226 0.015
regulation of actin filament length GO:0030832 56 0.014
actin filament bundle organization GO:0061572 54 0.014
atp catabolic process GO:0006200 157 0.014
regulation of proteolysis GO:0030162 293 0.014
actin filament organization GO:0007015 128 0.014
circulatory system development GO:0072359 262 0.014
inner ear morphogenesis GO:0042472 4 0.014
anion transport GO:0006820 161 0.014
positive regulation of catabolic process GO:0009896 310 0.014
regulation of protein polymerization GO:0032271 63 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
negative regulation of cell projection organization GO:0031345 22 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
sodium ion transport GO:0006814 61 0.014
regulation of locomotion GO:0040012 329 0.014
central nervous system development GO:0007417 123 0.014
positive regulation of developmental process GO:0051094 314 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
apoptotic signaling pathway GO:0097190 268 0.014
cell fate determination GO:0001709 3 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
protein processing GO:0016485 226 0.014
male genitalia development GO:0030539 1 0.014
regulation of ion transport GO:0043269 189 0.014
blood vessel development GO:0001568 172 0.014
purine containing compound catabolic process GO:0072523 411 0.014
fatty acid metabolic process GO:0006631 115 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
actin mediated cell contraction GO:0070252 12 0.013
positive regulation of cytoskeleton organization GO:0051495 83 0.013
negative regulation of developmental process GO:0051093 247 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
regulation of secretion GO:0051046 194 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
regulation of cellular response to stress GO:0080135 244 0.013
engulfment of apoptotic cell GO:0043652 2 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
cell part morphogenesis GO:0032990 137 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
protein deacylation GO:0035601 39 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
regulation of cell projection organization GO:0031344 107 0.013
actin filament based movement GO:0030048 17 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
long term memory GO:0007616 2 0.013
organ formation GO:0048645 3 0.013
protein targeting GO:0006605 187 0.013
regulation of map kinase activity GO:0043405 108 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
positive regulation of protein polymerization GO:0032273 45 0.013
establishment of protein localization to membrane GO:0090150 121 0.012
organic acid biosynthetic process GO:0016053 97 0.012
hindbrain development GO:0030902 3 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
primary neural tube formation GO:0014020 3 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of secretion by cell GO:1903530 177 0.012
rhythmic behavior GO:0007622 2 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
negative regulation of protein processing GO:0010955 142 0.012
protein oligomerization GO:0051259 173 0.012
meiotic chromosome segregation GO:0045132 4 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
actomyosin structure organization GO:0031032 59 0.012
regulation of response to external stimulus GO:0032101 222 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
regulation of cellular component size GO:0032535 82 0.012
signal transduction by p53 class mediator GO:0072331 72 0.012
regulation of protein localization GO:0032880 296 0.012
regulation of protein catabolic process GO:0042176 155 0.012
mitochondrion organization GO:0007005 156 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
negative regulation of dephosphorylation GO:0035305 63 0.012
response to cytokine GO:0034097 232 0.012
neuron differentiation GO:0030182 138 0.012
endocytosis GO:0006897 159 0.012
positive regulation of locomotion GO:0040017 186 0.012
regulation of transmembrane transport GO:0034762 139 0.012
positive regulation of response to dna damage stimulus GO:2001022 43 0.012
nerve development GO:0021675 4 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
cell division GO:0051301 168 0.012
regulation of homeostatic process GO:0032844 121 0.012
cell projection assembly GO:0030031 126 0.012
mrna metabolic process GO:0016071 175 0.012
regulation of protein transport GO:0051223 213 0.012
regulation of cell cycle GO:0051726 393 0.012
negative regulation of cell motility GO:2000146 104 0.012
lipid biosynthetic process GO:0008610 177 0.012
regulation of translation GO:0006417 89 0.011
response to oxygen containing compound GO:1901700 369 0.011
neuron development GO:0048666 113 0.011
nucleus localization GO:0051647 1 0.011
sequestering of metal ion GO:0051238 24 0.011
vasculature development GO:0001944 181 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
rna splicing GO:0008380 131 0.011
regulation of cell projection assembly GO:0060491 47 0.011
regulation of phosphatase activity GO:0010921 81 0.011
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.011
protein secretion GO:0009306 98 0.011
negative regulation of epithelial cell migration GO:0010633 38 0.011
striated muscle contraction GO:0006941 52 0.011
regulation of cell adhesion GO:0030155 166 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of immune system process GO:0002684 283 0.011
organelle assembly GO:0070925 176 0.011
cell projection morphogenesis GO:0048858 129 0.011
multi organism cellular process GO:0044764 156 0.011
hippocampus development GO:0021766 1 0.011
stem cell division GO:0017145 2 0.011
regulation of transporter activity GO:0032409 82 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
tube closure GO:0060606 3 0.011
receptor metabolic process GO:0043112 81 0.011
regulation of protein maturation GO:1903317 150 0.011
head development GO:0060322 108 0.011
regulation of gtpase activity GO:0043087 180 0.011
cell growth GO:0016049 160 0.011
plasma membrane organization GO:0007009 115 0.011
regulation of intracellular transport GO:0032386 195 0.011
tripartite regional subdivision GO:0007351 2 0.011
motor neuron axon guidance GO:0008045 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.011
peripheral nervous system development GO:0007422 2 0.011
nuclear transport GO:0051169 179 0.011
neural tube closure GO:0001843 3 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
neural tube formation GO:0001841 3 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
positive regulation of actin filament polymerization GO:0030838 38 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of cell cycle process GO:0010564 266 0.011
response to nitrogen compound GO:1901698 184 0.011
nucleocytoplasmic transport GO:0006913 176 0.010
mating GO:0007618 1 0.010
response to fungus GO:0009620 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
coenzyme metabolic process GO:0006732 65 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
metencephalon development GO:0022037 2 0.010
regulation of protein processing GO:0070613 150 0.010
reproductive process GO:0022414 106 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
behavioral response to ethanol GO:0048149 2 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
neuroblast proliferation GO:0007405 4 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
regulation of cell growth GO:0001558 135 0.010
rna interference GO:0016246 4 0.010
sulfur compound metabolic process GO:0006790 101 0.010
cellular ion homeostasis GO:0006873 168 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
cardiovascular system development GO:0072358 262 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
cerebral cortex radially oriented cell migration GO:0021799 1 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
endomembrane system organization GO:0010256 196 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
muscle system process GO:0003012 81 0.010
ruffle assembly GO:0097178 10 0.010
response to lipid GO:0033993 206 0.010
regulation of cytokine production GO:0001817 232 0.010
brain morphogenesis GO:0048854 1 0.010
stress fiber assembly GO:0043149 40 0.010

TTC19 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.061
inherited metabolic disorder DOID:655 242 0.044
musculoskeletal system disease DOID:17 223 0.029
sensory system disease DOID:0050155 203 0.024
eye and adnexa disease DOID:1492 150 0.024
nervous system disease DOID:863 431 0.024
eye disease DOID:5614 149 0.024
muscular disease DOID:0080000 114 0.023
muscle tissue disease DOID:66 113 0.023
myopathy DOID:423 104 0.022
cardiovascular system disease DOID:1287 106 0.021
amino acid metabolic disorder DOID:9252 50 0.019
muscular dystrophy DOID:9884 51 0.017
central nervous system disease DOID:331 186 0.017
neurodegenerative disease DOID:1289 102 0.017
retinal disease DOID:5679 118 0.015
immune system disease DOID:2914 155 0.013
hematopoietic system disease DOID:74 100 0.011
connective tissue disease DOID:65 109 0.011
retinal degeneration DOID:8466 89 0.011
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010