Homo sapiens

24 known processes

PPM1D

protein phosphatase, Mg2+/Mn2+ dependent, 1D

(Aliases: WIP1,PP2C-DELTA)

PPM1D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell cycle phase transition GO:1901988 89 0.518
negative regulation of cell cycle GO:0045786 193 0.480
cellular response to dna damage stimulus GO:0006974 379 0.364
regulation of cellular component biogenesis GO:0044087 281 0.329
positive regulation of programmed cell death GO:0043068 249 0.290
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.282
regulation of mitotic cell cycle GO:0007346 189 0.272
mitotic cell cycle GO:0000278 326 0.269
Mouse
regulation of proteolysis GO:0030162 293 0.258
internal protein amino acid acetylation GO:0006475 101 0.247
regulation of response to external stimulus GO:0032101 222 0.242
mitotic cell cycle phase transition GO:0044772 162 0.241
Mouse
histone acetylation GO:0016573 93 0.241
response to biotic stimulus GO:0009607 276 0.226
Mouse
internal peptidyl lysine acetylation GO:0018393 97 0.224
protein processing GO:0016485 226 0.221
regulation of cell cycle GO:0051726 393 0.215
post embryonic development GO:0009791 2 0.210
protein localization to organelle GO:0033365 280 0.199
peptidyl lysine acetylation GO:0018394 101 0.195
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.192
positive regulation of cell death GO:0010942 263 0.188
response to external biotic stimulus GO:0043207 261 0.179
Mouse
proteasomal protein catabolic process GO:0010498 176 0.168
secretion GO:0046903 254 0.168
positive regulation of apoptotic process GO:0043065 246 0.165
purine nucleotide catabolic process GO:0006195 405 0.163
locomotory behavior GO:0007626 1 0.154
response to other organism GO:0051707 261 0.149
Mouse
positive regulation of immune response GO:0050778 159 0.146
regulation of cell cycle process GO:0010564 266 0.143
defense response GO:0006952 315 0.140
protein catabolic process GO:0030163 325 0.136
glycosyl compound catabolic process GO:1901658 413 0.133
nucleoside triphosphate catabolic process GO:0009143 394 0.124
actin filament based process GO:0030029 224 0.122
apoptotic signaling pathway GO:0097190 268 0.121
negative regulation of cell cycle process GO:0010948 121 0.117
rho protein signal transduction GO:0007266 26 0.116
purine nucleoside triphosphate catabolic process GO:0009146 392 0.114
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.114
signal transduction in response to dna damage GO:0042770 57 0.110
endomembrane system organization GO:0010256 196 0.110
protein maturation GO:0051604 233 0.107
detection of muramyl dipeptide GO:0032498 1 0.107
protein acylation GO:0043543 138 0.105
nucleotide catabolic process GO:0009166 408 0.104
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.101
protein import into nucleus GO:0006606 104 0.101
ubiquitin dependent protein catabolic process GO:0006511 206 0.096
positive regulation of hydrolase activity GO:0051345 331 0.096
dna packaging GO:0006323 77 0.093
nucleoside triphosphate metabolic process GO:0009141 422 0.092
ribonucleoside triphosphate catabolic process GO:0009203 391 0.092
determination of adult lifespan GO:0008340 2 0.091
negative regulation of cell death GO:0060548 345 0.091
negative regulation of programmed cell death GO:0043069 321 0.090
protein localization to nucleus GO:0034504 136 0.089
nucleoside phosphate catabolic process GO:1901292 412 0.089
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.088
purine containing compound catabolic process GO:0072523 411 0.086
positive regulation of transport GO:0051050 336 0.086
regulation of cellular amino acid metabolic process GO:0006521 6 0.086
cellular component morphogenesis GO:0032989 314 0.084
peptidyl lysine modification GO:0018205 144 0.084
purine nucleoside catabolic process GO:0006152 398 0.083
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.083
negative regulation of multicellular organismal process GO:0051241 317 0.083
negative regulation of apoptotic process GO:0043066 316 0.082
response to oxygen containing compound GO:1901700 369 0.082
regulation of response to dna damage stimulus GO:2001020 94 0.081
signal transduction by p53 class mediator GO:0072331 72 0.081
nucleoside catabolic process GO:0009164 408 0.081
protein import GO:0017038 130 0.080
single organism cellular localization GO:1902580 332 0.077
secretion by cell GO:0032940 226 0.077
g1 s transition of mitotic cell cycle GO:0000082 78 0.077
cytoplasmic transport GO:0016482 379 0.077
cellular protein catabolic process GO:0044257 261 0.077
modification dependent macromolecule catabolic process GO:0043632 212 0.075
regulation of immune response GO:0050776 201 0.074
i kappab kinase nf kappab signaling GO:0007249 166 0.074
segmentation GO:0035282 4 0.073
dna repair GO:0006281 198 0.073
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.073
regulation of defense response GO:0031347 154 0.072
regulation of cysteine type endopeptidase activity GO:2000116 127 0.072
regulation of intracellular transport GO:0032386 195 0.072
oogenesis GO:0048477 2 0.072
positive regulation of cell cycle GO:0045787 140 0.071
protein targeting to nucleus GO:0044744 104 0.071
immune response GO:0006955 307 0.070
mitotic cell cycle checkpoint GO:0007093 68 0.070
regulation of peptidase activity GO:0052547 180 0.069
regulation of protein processing GO:0070613 150 0.068
ribonucleotide catabolic process GO:0009261 405 0.068
regulation of innate immune response GO:0045088 97 0.066
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.066
mitotic cell cycle process GO:1903047 286 0.065
Mouse
regulation of endopeptidase activity GO:0052548 170 0.065
regulation of apoptotic signaling pathway GO:2001233 175 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.065
intracellular protein transport GO:0006886 270 0.064
positive regulation of synaptic transmission GO:0050806 4 0.064
covalent chromatin modification GO:0016569 254 0.064
histone h3 acetylation GO:0043966 45 0.063
organophosphate catabolic process GO:0046434 430 0.061
purine ribonucleoside catabolic process GO:0046130 398 0.060
protein oligomerization GO:0051259 173 0.060
negative regulation of phosphate metabolic process GO:0045936 267 0.059
negative regulation of protein maturation GO:1903318 142 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.057
membrane organization GO:0061024 292 0.057
intrinsic apoptotic signaling pathway GO:0097193 127 0.056
cell cycle phase transition GO:0044770 173 0.056
Mouse
rna processing GO:0006396 255 0.056
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.056
regulation of protein maturation GO:1903317 150 0.056
single organism membrane organization GO:0044802 268 0.055
regulation of signal transduction by p53 class mediator GO:1901796 26 0.054
cellular amine metabolic process GO:0044106 41 0.054
negative regulation of protein metabolic process GO:0051248 391 0.054
regulation of cell cycle phase transition GO:1901987 126 0.054
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.053
negative regulation of cellular protein metabolic process GO:0032269 353 0.053
regulation of chromatin organization GO:1902275 56 0.052
positive regulation of cellular amine metabolic process GO:0033240 7 0.051
innate immune response GO:0045087 178 0.050
gtp catabolic process GO:0006184 237 0.050
cellular response to endogenous stimulus GO:0071495 336 0.049
vesicle mediated transport GO:0016192 371 0.049
cell cycle g1 s phase transition GO:0044843 80 0.048
negative regulation of apoptotic signaling pathway GO:2001234 97 0.048
single organism nuclear import GO:1902593 104 0.048
organelle assembly GO:0070925 176 0.047
striated muscle contraction GO:0006941 52 0.047
response to organonitrogen compound GO:0010243 156 0.047
nuclear import GO:0051170 106 0.047
protein ubiquitination GO:0016567 314 0.046
negative regulation of cellular catabolic process GO:0031330 83 0.046
gtp metabolic process GO:0046039 239 0.045
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.045
maintenance of location GO:0051235 112 0.045
regulation of cellular ketone metabolic process GO:0010565 50 0.045
protein homooligomerization GO:0051260 100 0.044
regulation of protein transport GO:0051223 213 0.044
positive regulation of ras gtpase activity GO:0032320 117 0.044
cellular macromolecule catabolic process GO:0044265 380 0.044
protein secretion GO:0009306 98 0.043
regulation of growth GO:0040008 165 0.043
positive regulation of cellular catabolic process GO:0031331 284 0.043
regulation of cellular component movement GO:0051270 334 0.043
regulation of dna metabolic process GO:0051052 153 0.042
protein targeting GO:0006605 187 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
positive regulation of intracellular transport GO:0032388 104 0.041
nucleocytoplasmic transport GO:0006913 176 0.041
taxis GO:0042330 157 0.041
ras protein signal transduction GO:0007265 73 0.041
positive regulation of catabolic process GO:0009896 310 0.040
mitochondrion organization GO:0007005 156 0.040
negative regulation of proteolysis GO:0045861 132 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.039
modification dependent protein catabolic process GO:0019941 209 0.039
histone modification GO:0016570 251 0.039
mitotic dna damage checkpoint GO:0044773 28 0.039
negative regulation of cell proliferation GO:0008285 228 0.039
histone h2a phosphorylation GO:1990164 3 0.039
regulation of mitotic cell cycle phase transition GO:1901990 118 0.039
ribonucleoside triphosphate metabolic process GO:0009199 412 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
ribonucleoside catabolic process GO:0042454 406 0.038
response to oxidative stress GO:0006979 121 0.038
enzyme linked receptor protein signaling pathway GO:0007167 303 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
anatomical structure formation involved in morphogenesis GO:0048646 284 0.038
cellular protein complex assembly GO:0043623 188 0.038
regulation of protein targeting GO:1903533 91 0.038
oocyte development GO:0048599 1 0.037
cellular amino acid metabolic process GO:0006520 116 0.037
adult locomotory behavior GO:0008344 1 0.037
intracellular mrna localization GO:0008298 1 0.037
chromatin modification GO:0016568 298 0.036
actin cytoskeleton organization GO:0030036 207 0.036
cellular response to growth factor stimulus GO:0071363 197 0.036
response to growth factor GO:0070848 205 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
cell substrate adhesion GO:0031589 132 0.035
maintenance of protein location GO:0045185 57 0.035
response to bacterium GO:0009617 144 0.034
Mouse
negative regulation of cellular component organization GO:0051129 235 0.034
regulation of protein localization GO:0032880 296 0.034
guanosine containing compound metabolic process GO:1901068 244 0.033
cell cycle arrest GO:0007050 71 0.033
lipid biosynthetic process GO:0008610 177 0.033
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.033
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.032
regulation of purine nucleotide catabolic process GO:0033121 205 0.032
endosomal transport GO:0016197 129 0.032
cell cycle checkpoint GO:0000075 117 0.032
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
protein autophosphorylation GO:0046777 123 0.032
regulation of cell morphogenesis GO:0022604 153 0.031
guanosine containing compound catabolic process GO:1901069 239 0.031
protein acetylation GO:0006473 116 0.031
regulation of protein import into nucleus GO:0042306 78 0.031
lipid metabolic process GO:0006629 381 0.031
negative regulation of protein processing GO:0010955 142 0.031
ameboidal type cell migration GO:0001667 135 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
female gamete generation GO:0007292 2 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
posttranscriptional regulation of gene expression GO:0010608 213 0.030
endocytosis GO:0006897 159 0.030
chromatin assembly GO:0031497 61 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
negative regulation of protein catabolic process GO:0042177 59 0.030
regulation of intracellular protein transport GO:0033157 123 0.030
positive regulation of cellular component biogenesis GO:0044089 158 0.029
detection of stimulus GO:0051606 85 0.029
activation of immune response GO:0002253 114 0.029
response to fungus GO:0009620 4 0.029
negative regulation of catabolic process GO:0009895 104 0.029
atp catabolic process GO:0006200 157 0.029
positive regulation of protein transport GO:0051222 135 0.029
defense response to other organism GO:0098542 129 0.029
regulation of protein localization to nucleus GO:1900180 85 0.029
translation GO:0006412 132 0.028
g1 dna damage checkpoint GO:0044783 18 0.028
dna templated transcription initiation GO:0006352 35 0.028
positive regulation of proteolysis GO:0045862 142 0.028
single organism carbohydrate metabolic process GO:0044723 193 0.028
multicellular organismal aging GO:0010259 3 0.028
positive regulation of endopeptidase activity GO:0010950 84 0.028
positive regulation of defense response GO:0031349 87 0.027
negative regulation of cellular protein catabolic process GO:1903363 38 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
muscle tissue development GO:0060537 62 0.027
positive regulation of apoptotic signaling pathway GO:2001235 70 0.027
apoptotic mitochondrial changes GO:0008637 57 0.027
oocyte differentiation GO:0009994 2 0.027
response to organic cyclic compound GO:0014070 204 0.027
meiotic chromosome segregation GO:0045132 4 0.027
behavior GO:0007610 112 0.027
protein modification by small protein removal GO:0070646 92 0.026
regulation of hormone levels GO:0010817 125 0.026
dna conformation change GO:0071103 113 0.026
mitotic dna integrity checkpoint GO:0044774 30 0.026
immune response regulating signaling pathway GO:0002764 97 0.026
cellular ketone metabolic process GO:0042180 80 0.026
regulation of rho protein signal transduction GO:0035023 79 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
memory GO:0007613 3 0.026
nucleoside monophosphate catabolic process GO:0009125 159 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
ribonucleoside monophosphate catabolic process GO:0009158 158 0.025
microtubule cytoskeleton organization GO:0000226 176 0.025
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.025
dna integrity checkpoint GO:0031570 71 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.025
regulation of cellular protein catabolic process GO:1903362 96 0.025
regulation of cellular response to stress GO:0080135 244 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of cell growth GO:0001558 135 0.025
lipid catabolic process GO:0016042 84 0.025
regulation of chromosome organization GO:0033044 103 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
microtubule based process GO:0007017 210 0.024
establishment of protein localization to organelle GO:0072594 172 0.024
nuclear transport GO:0051169 179 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
cellular response to extracellular stimulus GO:0031668 72 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.024
epithelial cell migration GO:0010631 119 0.024
maintenance of protein location in cell GO:0032507 56 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
response to starvation GO:0042594 59 0.024
negative regulation of growth GO:0045926 97 0.023
response to nitrogen compound GO:1901698 184 0.023
negative regulation of transport GO:0051051 176 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
cell morphogenesis GO:0000902 296 0.023
myosin filament assembly GO:0031034 2 0.023
positive regulation of immune system process GO:0002684 283 0.023
negative regulation of protein modification process GO:0031400 200 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
positive regulation of developmental process GO:0051094 314 0.022
regulation of response to wounding GO:1903034 101 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
regulation of cell motility GO:2000145 299 0.022
tripartite regional subdivision GO:0007351 2 0.022
regulation of cell migration GO:0030334 289 0.022
cell growth GO:0016049 160 0.022
amine metabolic process GO:0009308 44 0.022
anterior posterior axis specification GO:0009948 2 0.022
response to virus GO:0009615 126 0.022
positive regulation of peptidase activity GO:0010952 88 0.022
neuromuscular junction development GO:0007528 3 0.022
positive regulation of secretion by cell GO:1903532 108 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
hindlimb morphogenesis GO:0035137 2 0.022
tissue migration GO:0090130 119 0.021
negative regulation of chromosome organization GO:2001251 48 0.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.021
immune effector process GO:0002252 159 0.021
regulation of locomotion GO:0040012 329 0.021
blastoderm segmentation GO:0007350 2 0.021
system process GO:0003008 349 0.021
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.021
positive regulation of cellular component movement GO:0051272 181 0.021
detection of chemical stimulus GO:0009593 55 0.021
meiosis i GO:0007127 4 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
negative regulation of cell growth GO:0030308 83 0.021
activation of innate immune response GO:0002218 55 0.021
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
regeneration GO:0031099 4 0.020
macroautophagy GO:0016236 39 0.020
regulation of multi organism process GO:0043900 157 0.020
g2 m transition of mitotic cell cycle GO:0000086 41 0.020
Mouse
positive regulation of organelle organization GO:0010638 195 0.020
regulation of protein catabolic process GO:0042176 155 0.020
double strand break repair GO:0006302 101 0.020
response to glucagon GO:0033762 1 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
establishment of protein localization to membrane GO:0090150 121 0.020
regulation of immune effector process GO:0002697 91 0.020
response to insulin GO:0032868 45 0.020
positive regulation of response to dna damage stimulus GO:2001022 43 0.020
histone h4 acetylation GO:0043967 47 0.019
regulation of gtpase activity GO:0043087 180 0.019
dna damage checkpoint GO:0000077 68 0.019
response to abiotic stimulus GO:0009628 336 0.019
chromosome segregation GO:0007059 114 0.019
cellular response to radiation GO:0071478 65 0.019
negative regulation of response to wounding GO:1903035 47 0.019
cellular response to cytokine stimulus GO:0071345 181 0.019
cell development GO:0048468 328 0.019
regulation of inflammatory response GO:0050727 46 0.018
inflammatory response GO:0006954 79 0.018
neurological system process GO:0050877 163 0.018
regulation of antimicrobial humoral response GO:0002759 1 0.018
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.018
blood vessel morphogenesis GO:0048514 162 0.018
circadian sleep wake cycle sleep GO:0050802 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
cell projection organization GO:0030030 252 0.018
rhythmic behavior GO:0007622 2 0.018
actin filament organization GO:0007015 128 0.018
positive regulation of rho protein signal transduction GO:0035025 4 0.018
muscle structure development GO:0061061 98 0.018
chromatin organization GO:0006325 351 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
epithelium migration GO:0090132 119 0.018
autophagy GO:0006914 88 0.018
regulation of protein secretion GO:0050708 86 0.018
regulation of synaptic transmission dopaminergic GO:0032225 4 0.018
regulation of protein stability GO:0031647 87 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
positive regulation of protein catabolic process GO:0045732 75 0.018
mitotic nuclear division GO:0007067 119 0.018
nuclear division GO:0000280 128 0.018
cytokine production GO:0001816 247 0.017
response to nutrient levels GO:0031667 81 0.017
vesicle organization GO:0016050 62 0.017
blastocyst development GO:0001824 3 0.017
positive regulation of gtpase activity GO:0043547 166 0.017
regulation of cell development GO:0060284 161 0.017
regulation of translation GO:0006417 89 0.017
positive regulation of transferase activity GO:0051347 227 0.017
regulation of secretion GO:0051046 194 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
protein stabilization GO:0050821 64 0.017
cardiovascular system development GO:0072358 262 0.017
interleukin 1 secretion GO:0050701 18 0.017
response to lipid GO:0033993 206 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
biological adhesion GO:0022610 331 0.017
nucleosome assembly GO:0006334 50 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
negative regulation of response to external stimulus GO:0032102 83 0.017
cellular response to starvation GO:0009267 58 0.016
glycosylation GO:0070085 71 0.016
maintenance of location in cell GO:0051651 62 0.016
cellular response to external stimulus GO:0071496 111 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
mrna processing GO:0006397 133 0.016
striated muscle tissue development GO:0014706 59 0.016
zymogen activation GO:0031638 70 0.016
cell adhesion GO:0007155 325 0.016
skeletal muscle tissue growth GO:0048630 2 0.016
humoral immune response GO:0006959 49 0.016
dephosphorylation GO:0016311 209 0.016
cell aging GO:0007569 52 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
negative regulation of organelle organization GO:0010639 126 0.016
positive regulation of protein localization to nucleus GO:1900182 48 0.016
leukocyte chemotaxis GO:0030595 76 0.016
defense response to fungus GO:0050832 4 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
regulation of histone acetylation GO:0035065 19 0.016
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
wnt signaling pathway GO:0016055 156 0.016
regulation of meiosis GO:0040020 3 0.016
response to uv GO:0009411 73 0.016
innate immune response activating signal transduction GO:0002758 48 0.016
embryonic hindlimb morphogenesis GO:0035116 2 0.015
cardiac muscle contraction GO:0060048 34 0.015
chromosome separation GO:0051304 23 0.015
retrograde transport endosome to golgi GO:0042147 45 0.015
chemotaxis GO:0006935 157 0.015
vacuole organization GO:0007033 44 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.015
response to molecule of bacterial origin GO:0002237 82 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.015
cell matrix adhesion GO:0007160 85 0.015
negative regulation of immune system process GO:0002683 136 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
hormone metabolic process GO:0042445 61 0.015
response to testosterone GO:0033574 1 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.015
oxidation reduction process GO:0055114 396 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
positive regulation of chromatin modification GO:1903310 30 0.015
androgen biosynthetic process GO:0006702 3 0.015
myoblast fusion GO:0007520 1 0.015
peptide transport GO:0015833 74 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.015
regulation of protein kinase activity GO:0045859 289 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.015
response to radiation GO:0009314 151 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
steroid metabolic process GO:0008202 94 0.014
muscle system process GO:0003012 81 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
vitamin d receptor signaling pathway GO:0070561 4 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
dna dependent dna replication GO:0006261 44 0.014
cellular response to nutrient levels GO:0031669 69 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
carbohydrate metabolic process GO:0005975 207 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
cell part morphogenesis GO:0032990 137 0.014
nucleus organization GO:0006997 28 0.014
negative regulation of secretion by cell GO:1903531 52 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
mating GO:0007618 1 0.013
vacuolar transport GO:0007034 34 0.013
methylation GO:0032259 106 0.013
genetic imprinting GO:0071514 1 0.013
lysosomal transport GO:0007041 33 0.013
lipid localization GO:0010876 106 0.013
circadian behavior GO:0048512 2 0.013
stress fiber assembly GO:0043149 40 0.013
macromolecule glycosylation GO:0043413 63 0.013
nucleotide excision repair GO:0006289 31 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
sleep GO:0030431 2 0.013

PPM1D disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.050
nervous system disease DOID:863 431 0.050
musculoskeletal system disease DOID:17 223 0.035
bone disease DOID:0080001 88 0.031
connective tissue disease DOID:65 109 0.031
immune system disease DOID:2914 155 0.024
aplastic anemia DOID:12449 30 0.024
bone marrow disease DOID:4961 31 0.024
anemia DOID:2355 55 0.024
hematopoietic system disease DOID:74 100 0.024
neurodegenerative disease DOID:1289 102 0.023
disease of cellular proliferation DOID:14566 174 0.021
disease of mental health DOID:150 70 0.021
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
neuropathy DOID:870 52 0.017
myopathy DOID:423 104 0.016
congenital muscular dystrophy DOID:0050557 22 0.016
muscular disease DOID:0080000 114 0.016
muscular dystrophy DOID:9884 51 0.016
muscle tissue disease DOID:66 113 0.016
heart disease DOID:114 68 0.015
cardiovascular system disease DOID:1287 106 0.015