Homo sapiens

35 known processes

PJA2

praja ring finger 2

(Aliases: RNF131,KIAA0438,Neurodap1)

PJA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.863
modification dependent protein catabolic process GO:0019941 209 0.857
protein ubiquitination GO:0016567 314 0.835
cellular macromolecule catabolic process GO:0044265 380 0.818
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.798
modification dependent macromolecule catabolic process GO:0043632 212 0.769
cellular protein catabolic process GO:0044257 261 0.708
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.681
proteasomal protein catabolic process GO:0010498 176 0.593
protein modification by small protein conjugation GO:0032446 342 0.570
protein k48 linked ubiquitination GO:0070936 38 0.391
cytoplasmic transport GO:0016482 379 0.371
protein catabolic process GO:0030163 325 0.319
protein autoubiquitination GO:0051865 37 0.289
intracellular protein transport GO:0006886 270 0.277
vesicle mediated transport GO:0016192 371 0.273
ubiquitin dependent protein catabolic process GO:0006511 206 0.247
mitochondrion organization GO:0007005 156 0.247
regulation of cellular component biogenesis GO:0044087 281 0.229
membrane organization GO:0061024 292 0.224
regulation of protein localization GO:0032880 296 0.207
cellular response to endogenous stimulus GO:0071495 336 0.173
regulation of cytoplasmic transport GO:1903649 149 0.169
negative regulation of catalytic activity GO:0043086 335 0.154
protein localization to organelle GO:0033365 280 0.153
single organism membrane organization GO:0044802 268 0.128
positive regulation of transport GO:0051050 336 0.127
nucleoside catabolic process GO:0009164 408 0.125
ribonucleoside triphosphate catabolic process GO:0009203 391 0.117
glycosyl compound catabolic process GO:1901658 413 0.110
oogenesis GO:0048477 2 0.107
negative regulation of phosphate metabolic process GO:0045936 267 0.102
primary neural tube formation GO:0014020 3 0.098
organelle fission GO:0048285 149 0.093
regulation of protein complex assembly GO:0043254 147 0.090
regulation of intracellular transport GO:0032386 195 0.086
negative regulation of protein metabolic process GO:0051248 391 0.084
regulation of nucleoside metabolic process GO:0009118 209 0.082
gtp catabolic process GO:0006184 237 0.081
drug transmembrane transport GO:0006855 7 0.081
nucleocytoplasmic transport GO:0006913 176 0.080
cell development GO:0048468 328 0.078
organophosphate catabolic process GO:0046434 430 0.075
post embryonic development GO:0009791 2 0.074
guanosine containing compound metabolic process GO:1901068 244 0.072
negative regulation of phosphorus metabolic process GO:0010563 267 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.070
regulation of nucleotide catabolic process GO:0030811 205 0.069
female gamete generation GO:0007292 2 0.067
regulation of locomotion GO:0040012 329 0.066
ribonucleotide catabolic process GO:0009261 405 0.066
response to endoplasmic reticulum stress GO:0034976 49 0.063
guanosine containing compound catabolic process GO:1901069 239 0.061
regulation of purine nucleotide metabolic process GO:1900542 264 0.061
nucleotide catabolic process GO:0009166 408 0.060
actin cytoskeleton organization GO:0030036 207 0.060
oocyte development GO:0048599 1 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
cellular response to nitrogen compound GO:1901699 144 0.055
microtubule organizing center organization GO:0031023 62 0.054
cellular protein complex assembly GO:0043623 188 0.052
regulation of cellular response to stress GO:0080135 244 0.051
nucleoside triphosphate metabolic process GO:0009141 422 0.051
protein localization to nucleus GO:0034504 136 0.050
neural tube closure GO:0001843 3 0.049
morphogenesis of embryonic epithelium GO:0016331 4 0.049
negative regulation of multicellular organismal process GO:0051241 317 0.048
cellular response to topologically incorrect protein GO:0035967 19 0.047
regulation of protein catabolic process GO:0042176 155 0.046
oocyte differentiation GO:0009994 2 0.046
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
memory GO:0007613 3 0.045
Rat
apoptotic signaling pathway GO:0097190 268 0.043
secretion GO:0046903 254 0.043
endomembrane system organization GO:0010256 196 0.043
cellular amino acid metabolic process GO:0006520 116 0.042
sleep GO:0030431 2 0.042
glycoprotein metabolic process GO:0009100 110 0.041
single organism cellular localization GO:1902580 332 0.041
regulation of cell cycle GO:0051726 393 0.041
ras protein signal transduction GO:0007265 73 0.039
regulation of gtpase activity GO:0043087 180 0.039
regulation of small gtpase mediated signal transduction GO:0051056 156 0.039
endocytosis GO:0006897 159 0.038
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.037
negative regulation of hydrolase activity GO:0051346 182 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
cell adhesion GO:0007155 325 0.037
protein dephosphorylation GO:0006470 81 0.037
positive regulation of cellular component organization GO:0051130 376 0.036
purine ribonucleoside catabolic process GO:0046130 398 0.036
regulation of protein transport GO:0051223 213 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
regulation of gtp catabolic process GO:0033124 180 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
cellular component morphogenesis GO:0032989 314 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
cell projection organization GO:0030030 252 0.032
actin filament based process GO:0030029 224 0.032
system process GO:0003008 349 0.032
Rat
protein monoubiquitination GO:0006513 39 0.032
phospholipid translocation GO:0045332 2 0.031
golgi vesicle transport GO:0048193 80 0.031
regulation of cellular protein catabolic process GO:1903362 96 0.031
segmentation GO:0035282 4 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.030
regulation of multi organism process GO:0043900 157 0.030
long term memory GO:0007616 2 0.029
Rat
embryonic epithelial tube formation GO:0001838 4 0.029
actin filament organization GO:0007015 128 0.029
anion transport GO:0006820 161 0.028
dephosphorylation GO:0016311 209 0.028
neurogenesis GO:0022008 169 0.028
regulation of proteolysis GO:0030162 293 0.027
regulation of cardiac muscle hypertrophy in response to stress GO:1903242 2 0.026
regulation of nucleocytoplasmic transport GO:0046822 98 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
centrosome organization GO:0051297 58 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
regulation of oocyte maturation GO:1900193 1 0.026
embryo development GO:0009790 123 0.025
vacuole organization GO:0007033 44 0.025
regulation of cell migration GO:0030334 289 0.025
camp metabolic process GO:0046058 61 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.024
male meiosis GO:0007140 1 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
behavior GO:0007610 112 0.024
Rat
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
positive regulation of gtp catabolic process GO:0033126 166 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.023
small molecule biosynthetic process GO:0044283 157 0.023
glycoprotein biosynthetic process GO:0009101 91 0.023
regulation of proteasomal protein catabolic process GO:0061136 87 0.023
microtubule based process GO:0007017 210 0.023
neuron development GO:0048666 113 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
negative regulation of transport GO:0051051 176 0.022
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.022
nitrogen compound transport GO:0071705 191 0.022
synaptic vesicle recycling GO:0036465 3 0.022
cardiac muscle adaptation GO:0014887 4 0.022
lipid localization GO:0010876 106 0.022
response to abiotic stimulus GO:0009628 336 0.022
purine nucleoside catabolic process GO:0006152 398 0.021
heart development GO:0007507 95 0.021
organelle assembly GO:0070925 176 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
regulation of cell maturation GO:1903429 3 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
inner ear morphogenesis GO:0042472 4 0.020
locomotory behavior GO:0007626 1 0.020
nuclear transport GO:0051169 179 0.020
negative regulation of protein modification process GO:0031400 200 0.020
adult locomotory behavior GO:0008344 1 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
gtp metabolic process GO:0046039 239 0.019
wnt signaling pathway GO:0016055 156 0.019
cell cycle checkpoint GO:0000075 117 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
positive regulation of organelle organization GO:0010638 195 0.019
regulation of camp biosynthetic process GO:0030817 45 0.019
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
regulation of dephosphorylation GO:0035303 96 0.018
negative regulation of protein transport GO:0051224 75 0.018
protein targeting GO:0006605 187 0.018
positive regulation of immune system process GO:0002684 283 0.018
cellular response to misfolded protein GO:0071218 2 0.018
positive regulation of catabolic process GO:0009896 310 0.018
response to growth factor GO:0070848 205 0.017
purine containing compound catabolic process GO:0072523 411 0.017
vesicle organization GO:0016050 62 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
organelle localization GO:0051640 84 0.017
regulation of protein localization to nucleus GO:1900180 85 0.017
reproduction GO:0000003 63 0.017
histone h2a ubiquitination GO:0033522 17 0.017
protein localization to membrane GO:0072657 160 0.017
determination of adult lifespan GO:0008340 2 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
negative regulation of transferase activity GO:0051348 124 0.016
defense response to virus GO:0051607 71 0.016
regulation of membrane potential GO:0042391 95 0.016
positive regulation of locomotion GO:0040017 186 0.016
positive regulation of protein transport GO:0051222 135 0.016
single organism reproductive process GO:0044702 98 0.016
multi organism cellular process GO:0044764 156 0.016
cellular homeostasis GO:0019725 196 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
multi organism reproductive process GO:0044703 54 0.016
neuroblast proliferation GO:0007405 4 0.015
androgen receptor signaling pathway GO:0030521 34 0.015
rho protein signal transduction GO:0007266 26 0.015
organic acid biosynthetic process GO:0016053 97 0.015
regulation of cell development GO:0060284 161 0.015
positive regulation of wnt signaling pathway GO:0030177 54 0.015
regulation of phosphatase activity GO:0010921 81 0.015
immune effector process GO:0002252 159 0.015
neural tube formation GO:0001841 3 0.015
metal ion transport GO:0030001 272 0.015
positive regulation of cell development GO:0010720 92 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of protein stability GO:0031647 87 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
cellular amide metabolic process GO:0043603 69 0.014
multicellular organismal aging GO:0010259 3 0.014
defense response to other organism GO:0098542 129 0.014
regulation of protein kinase activity GO:0045859 289 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
regulation of secretion GO:0051046 194 0.014
regulation of t cell activation GO:0050863 77 0.013
response to virus GO:0009615 126 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
genetic imprinting GO:0071514 1 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of transferase activity GO:0051338 355 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
protein localization to plasma membrane GO:0072659 93 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
positive regulation of sequestering of triglyceride GO:0010890 3 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
generation of neurons GO:0048699 152 0.013
positive regulation of protein ubiquitination GO:0031398 53 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
regulation of phagocytosis engulfment GO:0060099 2 0.013
reproductive process GO:0022414 106 0.013
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.013
single organism nuclear import GO:1902593 104 0.013
chemical homeostasis GO:0048878 306 0.013
response to oxygen containing compound GO:1901700 369 0.013
spermatid development GO:0007286 4 0.013
organ morphogenesis GO:0009887 147 0.013
regulation of immune effector process GO:0002697 91 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
negative regulation of transcription factor import into nucleus GO:0042992 17 0.013
regulation of intracellular protein transport GO:0033157 123 0.012
positive regulation of secretion GO:0051047 116 0.012
cell morphogenesis GO:0000902 296 0.012
response to nitrogen compound GO:1901698 184 0.012
oxidation reduction process GO:0055114 396 0.012
protein glycosylation GO:0006486 62 0.012
mitotic cell cycle process GO:1903047 286 0.012
divalent inorganic cation transport GO:0072511 158 0.012
cellular response to organonitrogen compound GO:0071417 124 0.012
somitogenesis GO:0001756 2 0.012
actomyosin structure organization GO:0031032 59 0.012
regulation of kinase activity GO:0043549 314 0.012
regulation of cardiac muscle adaptation GO:0010612 2 0.012
circulatory system development GO:0072359 262 0.012
regulation of protein targeting GO:1903533 91 0.012
associative learning GO:0008306 1 0.012
chemotaxis GO:0006935 157 0.012
maintenance of protein location GO:0045185 57 0.012
tube closure GO:0060606 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of cell adhesion GO:0030155 166 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
er nucleus signaling pathway GO:0006984 23 0.011
positive regulation of adenylate cyclase activity GO:0045762 12 0.011
nuclear division GO:0000280 128 0.011
defense response GO:0006952 315 0.011
negative regulation of catabolic process GO:0009895 104 0.011
negative regulation of organelle organization GO:0010639 126 0.011
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.011
positive regulation of defense response GO:0031349 87 0.011
protein targeting to nucleus GO:0044744 104 0.011
regulation of cell cycle process GO:0010564 266 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
maintenance of location GO:0051235 112 0.010
amine metabolic process GO:0009308 44 0.010
positive regulation of cell cycle GO:0045787 140 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
nervous system development GO:0007399 293 0.010
metal ion homeostasis GO:0055065 169 0.010
regulation of secretion by cell GO:1903530 177 0.010
tissue morphogenesis GO:0048729 96 0.010
receptor mediated endocytosis GO:0006898 84 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
negative regulation of cell maturation GO:1903430 2 0.010
maintenance of location in cell GO:0051651 62 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010

PJA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
papillary thyroid carcinoma DOID:3969 6 0.027
thyroid carcinoma DOID:3963 13 0.027
endocrine gland cancer DOID:170 26 0.027
organ system cancer DOID:0050686 164 0.027
thyroid cancer DOID:1781 13 0.027
disease of cellular proliferation DOID:14566 174 0.027
cancer DOID:162 167 0.027
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
eye and adnexa disease DOID:1492 150 0.013
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.013
eye disease DOID:5614 149 0.013