Homo sapiens

111 known processes

PTPN3

protein tyrosine phosphatase, non-receptor type 3

(Aliases: PTPH1,DKFZp686N0569)

PTPN3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.693
branched chain amino acid metabolic process GO:0009081 4 0.563
regulation of cellular ketone metabolic process GO:0010565 50 0.429
peptidyl tyrosine dephosphorylation GO:0035335 36 0.376
taurine metabolic process GO:0019530 1 0.350
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 2 0.338
cellular amino acid metabolic process GO:0006520 116 0.334
cellular ketone metabolic process GO:0042180 80 0.304
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.295
regulation of hepatocyte growth factor receptor signaling pathway GO:1902202 4 0.288
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.261
cellular amine metabolic process GO:0044106 41 0.256
regulation of cellular amine metabolic process GO:0033238 11 0.255
regulation of interleukin 6 mediated signaling pathway GO:0070103 3 0.242
carbohydrate metabolic process GO:0005975 207 0.233
creatinine metabolic process GO:0046449 1 0.223
negative regulation of cellular amine metabolic process GO:0033239 3 0.220
protein dephosphorylation GO:0006470 81 0.220
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.219
regulation of protein kinase activity GO:0045859 289 0.218
dicarboxylic acid metabolic process GO:0043648 29 0.212
regulation of cellular amino acid metabolic process GO:0006521 6 0.211
amine metabolic process GO:0009308 44 0.209
positive regulation of developmental process GO:0051094 314 0.208
av node cell to bundle of his cell communication GO:0086067 4 0.202
negative regulation of phosphate metabolic process GO:0045936 267 0.200
organ morphogenesis GO:0009887 147 0.181
regulation of transferase activity GO:0051338 355 0.178
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.175
type i interferon signaling pathway GO:0060337 11 0.173
cellular lactam metabolic process GO:0072338 1 0.168
negative regulation of protein modification process GO:0031400 200 0.165
negative regulation of cell proliferation GO:0008285 228 0.164
Human
regulation of kinase activity GO:0043549 314 0.160
cytokine mediated signaling pathway GO:0019221 109 0.155
actin filament based process GO:0030029 224 0.146
dephosphorylation GO:0016311 209 0.143
purine containing compound catabolic process GO:0072523 411 0.142
negative regulation of phosphorylation GO:0042326 174 0.141
cellular lipid metabolic process GO:0044255 303 0.137
negative regulation of protein metabolic process GO:0051248 391 0.137
immune response GO:0006955 307 0.131
oxaloacetate metabolic process GO:0006107 1 0.130
enzyme linked receptor protein signaling pathway GO:0007167 303 0.127
peptidyl tyrosine phosphorylation GO:0018108 170 0.127
single organism carbohydrate metabolic process GO:0044723 193 0.126
negative regulation of phosphorus metabolic process GO:0010563 267 0.122
guanosine containing compound catabolic process GO:1901069 239 0.122
gtp metabolic process GO:0046039 239 0.122
ras protein signal transduction GO:0007265 73 0.122
positive regulation of cellular amine metabolic process GO:0033240 7 0.116
peptidyl tyrosine modification GO:0018212 170 0.116
succinate metabolic process GO:0006105 1 0.115
response to cytokine GO:0034097 232 0.114
cellular response to endogenous stimulus GO:0071495 336 0.114
negative regulation of protein phosphorylation GO:0001933 140 0.113
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.111
cellular macromolecular complex assembly GO:0034622 324 0.111
positive regulation of protein phosphorylation GO:0001934 313 0.109
regulation of mapk cascade GO:0043408 262 0.109
negative regulation of macrophage differentiation GO:0045650 2 0.108
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.107
cell development GO:0048468 328 0.106
nucleoside triphosphate metabolic process GO:0009141 422 0.101
cellular response to cytokine stimulus GO:0071345 181 0.101
cellular response to oxygen containing compound GO:1901701 276 0.099
defense response GO:0006952 315 0.098
fatty acid metabolic process GO:0006631 115 0.098
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.097
regulation of nucleoside metabolic process GO:0009118 209 0.095
signal transduction by phosphorylation GO:0023014 297 0.095
citrate metabolic process GO:0006101 2 0.094
regulation of anatomical structure morphogenesis GO:0022603 286 0.090
growth GO:0040007 202 0.090
regulation of protein serine threonine kinase activity GO:0071900 179 0.089
rab protein signal transduction GO:0032482 4 0.088
tricarboxylic acid metabolic process GO:0072350 4 0.088
nucleoside catabolic process GO:0009164 408 0.087
small gtpase mediated signal transduction GO:0007264 78 0.087
regulation of purine nucleotide metabolic process GO:1900542 264 0.087
cell morphogenesis GO:0000902 296 0.087
response to oxygen containing compound GO:1901700 369 0.085
negative regulation of intracellular signal transduction GO:1902532 183 0.085
sulfur compound metabolic process GO:0006790 101 0.084
response to calcium ion GO:0051592 46 0.084
ribonucleoside triphosphate catabolic process GO:0009203 391 0.083
interleukin 2 mediated signaling pathway GO:0038110 3 0.083
positive regulation of protein kinase activity GO:0045860 190 0.082
vesicle mediated transport GO:0016192 371 0.081
regulation of gtpase activity GO:0043087 180 0.080
negative regulation of defense response GO:0031348 47 0.079
cardiac muscle cell contraction GO:0086003 4 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.079
regulation of nucleotide catabolic process GO:0030811 205 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.078
nucleoside phosphate catabolic process GO:1901292 412 0.078
ribonucleoside triphosphate metabolic process GO:0009199 412 0.077
endochondral bone morphogenesis GO:0060350 3 0.077
purine nucleotide catabolic process GO:0006195 405 0.077
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.076
alpha amino acid metabolic process GO:1901605 72 0.075
negative regulation of jak stat cascade GO:0046426 4 0.075
guanosine containing compound metabolic process GO:1901068 244 0.075
positive regulation of nucleotide metabolic process GO:0045981 230 0.075
gtp catabolic process GO:0006184 237 0.073
ribonucleotide catabolic process GO:0009261 405 0.073
negative regulation of type i interferon mediated signaling pathway GO:0060339 4 0.072
positive regulation of heart rate GO:0010460 4 0.072
lipid metabolic process GO:0006629 381 0.072
hindbrain development GO:0030902 3 0.070
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.069
positive regulation of phosphorylation GO:0042327 394 0.069
rho protein signal transduction GO:0007266 26 0.069
positive regulation of catabolic process GO:0009896 310 0.068
response to organonitrogen compound GO:0010243 156 0.067
hormone mediated signaling pathway GO:0009755 22 0.067
ribonucleoside catabolic process GO:0042454 406 0.067
regulation of vesicle mediated transport GO:0060627 130 0.066
memory GO:0007613 3 0.066
positive regulation of gtpase activity GO:0043547 166 0.066
positive regulation of transferase activity GO:0051347 227 0.065
regulation of cytokine mediated signaling pathway GO:0001959 41 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.064
nervous system development GO:0007399 293 0.064
endomembrane system organization GO:0010256 196 0.062
monocarboxylic acid metabolic process GO:0032787 185 0.061
ion transmembrane transport GO:0034220 338 0.061
positive regulation of nucleoside metabolic process GO:0045979 186 0.060
purine nucleoside catabolic process GO:0006152 398 0.059
regulation of small gtpase mediated signal transduction GO:0051056 156 0.058
purine ribonucleoside metabolic process GO:0046128 437 0.058
regulation of membrane potential GO:0042391 95 0.058
regulation of nucleotide metabolic process GO:0006140 269 0.057
positive regulation of rab gtpase activity GO:0032851 39 0.057
regulation of ras protein signal transduction GO:0046578 155 0.057
secretion GO:0046903 254 0.056
cellular protein complex assembly GO:0043623 188 0.056
regulation of purine nucleotide catabolic process GO:0033121 205 0.056
cellular response to nitrogen compound GO:1901699 144 0.056
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.055
positive regulation of kinase activity GO:0033674 204 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.055
long term memory GO:0007616 2 0.053
regulation of immune response GO:0050776 201 0.053
segmentation GO:0035282 4 0.053
single organism membrane organization GO:0044802 268 0.052
photoreceptor cell differentiation GO:0046530 2 0.052
activation of jak2 kinase activity GO:0042977 5 0.052
2 oxoglutarate metabolic process GO:0006103 4 0.052
neuromuscular junction development GO:0007528 3 0.052
regulation of cell differentiation GO:0045595 393 0.052
negative regulation of kinase activity GO:0033673 106 0.051
generation of neurons GO:0048699 152 0.051
regulation of cellular component biogenesis GO:0044087 281 0.050
purine ribonucleotide catabolic process GO:0009154 404 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
somatic stem cell division GO:0048103 1 0.049
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
anterior posterior axis specification embryo GO:0008595 2 0.049
regulation of ras gtpase activity GO:0032318 128 0.049
protein localization to membrane GO:0072657 160 0.048
regulation of gtp catabolic process GO:0033124 180 0.048
regulation of jak stat cascade GO:0046425 44 0.048
cellular modified amino acid metabolic process GO:0006575 64 0.048
regulation of rab gtpase activity GO:0032313 39 0.047
positive regulation of gtp catabolic process GO:0033126 166 0.047
glycosyl compound catabolic process GO:1901658 413 0.047
positive regulation of ras gtpase activity GO:0032320 117 0.046
anterior posterior axis specification GO:0009948 2 0.046
response to food GO:0032094 1 0.046
negative regulation of bile acid biosynthetic process GO:0070858 3 0.046
negative regulation of response to cytokine stimulus GO:0060761 25 0.046
intracellular bile acid receptor signaling pathway GO:0038185 1 0.045
jak stat cascade GO:0007259 46 0.045
innate immune response GO:0045087 178 0.045
organophosphate catabolic process GO:0046434 430 0.045
metencephalon development GO:0022037 2 0.045
female gamete generation GO:0007292 2 0.045
locomotory behavior GO:0007626 1 0.045
nucleotide catabolic process GO:0009166 408 0.044
cellular response to interleukin 15 GO:0071350 6 0.044
cell projection organization GO:0030030 252 0.044
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.044
lipid biosynthetic process GO:0008610 177 0.043
post embryonic development GO:0009791 2 0.043
response to interleukin 1 GO:0070555 47 0.043
positive regulation of nucleotide catabolic process GO:0030813 185 0.043
positive regulation of cellular catabolic process GO:0031331 284 0.043
cellular component morphogenesis GO:0032989 314 0.042
receptor metabolic process GO:0043112 81 0.042
metal ion transport GO:0030001 272 0.041
neuroblast proliferation GO:0007405 4 0.041
blood circulation GO:0008015 113 0.040
actin filament based movement GO:0030048 17 0.040
single organism cellular localization GO:1902580 332 0.039
cellular carbohydrate metabolic process GO:0044262 84 0.039
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.039
response to cycloheximide GO:0046898 1 0.039
skeletal system development GO:0001501 79 0.038
regulation of ion transport GO:0043269 189 0.038
microtubule cytoskeleton organization GO:0000226 176 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
negative regulation of cell growth GO:0030308 83 0.038
receptor internalization GO:0031623 43 0.037
oocyte development GO:0048599 1 0.037
multicellular organismal metabolic process GO:0044236 34 0.037
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.037
circulatory system process GO:0003013 113 0.037
mapk cascade GO:0000165 288 0.037
maintenance of location GO:0051235 112 0.036
negative regulation of mapk cascade GO:0043409 56 0.036
cell projection morphogenesis GO:0048858 129 0.036
regulation of protein localization GO:0032880 296 0.036
Human
response to nitrogen compound GO:1901698 184 0.036
endocytosis GO:0006897 159 0.036
cellular response to hormone stimulus GO:0032870 125 0.035
neuronal stem cell division GO:0036445 1 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
regulation of cellular protein catabolic process GO:1903362 96 0.035
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.035
oxidation reduction process GO:0055114 396 0.035
actin mediated cell contraction GO:0070252 12 0.035
cellular amide metabolic process GO:0043603 69 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
behavior GO:0007610 112 0.034
regulation of rab protein signal transduction GO:0032483 39 0.034
monovalent inorganic cation transport GO:0015672 128 0.034
oocyte differentiation GO:0009994 2 0.034
regulation of growth GO:0040008 165 0.034
regulation of innate immune response GO:0045088 97 0.033
multicellular organismal aging GO:0010259 3 0.033
positive regulation of cell death GO:0010942 263 0.033
activation of protein kinase activity GO:0032147 90 0.033
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.033
response to lipid GO:0033993 206 0.033
neuroblast division GO:0055057 1 0.033
anion transport GO:0006820 161 0.032
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.032
regulation of map kinase activity GO:0043405 108 0.032
regulation of proteolysis GO:0030162 293 0.032
ion homeostasis GO:0050801 230 0.032
positive regulation of immune system process GO:0002684 283 0.032
protein catabolic process GO:0030163 325 0.032
membrane organization GO:0061024 292 0.032
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
determination of adult lifespan GO:0008340 2 0.032
regulation of system process GO:0044057 101 0.031
regulation of type i interferon mediated signaling pathway GO:0060338 9 0.031
single organism cell adhesion GO:0098602 179 0.031
glucose metabolic process GO:0006006 45 0.031
epithelium development GO:0060429 227 0.031
response to extracellular stimulus GO:0009991 85 0.031
negative regulation of developmental process GO:0051093 247 0.030
cerebellum development GO:0021549 2 0.030
taxis GO:0042330 157 0.030
negative regulation of cellular component organization GO:0051129 235 0.030
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.030
oogenesis GO:0048477 2 0.029
receptor mediated endocytosis GO:0006898 84 0.029
response to abiotic stimulus GO:0009628 336 0.029
activation of immune response GO:0002253 114 0.029
positive regulation of mapk cascade GO:0043410 190 0.029
response to interleukin 15 GO:0070672 6 0.029
response to peptide GO:1901652 65 0.029
protein targeting GO:0006605 187 0.028
motor neuron axon guidance GO:0008045 2 0.028
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
chemotaxis GO:0006935 157 0.028
microtubule based process GO:0007017 210 0.028
cdc42 protein signal transduction GO:0032488 4 0.027
morphogenesis of a polarized epithelium GO:0001738 3 0.027
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.027
response to insulin GO:0032868 45 0.027
chemical homeostasis GO:0048878 306 0.027
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.027
negative regulation of cell death GO:0060548 345 0.026
cellular response to peptide hormone stimulus GO:0071375 56 0.026
negative regulation of interleukin 6 mediated signaling pathway GO:0070104 2 0.026
response to inorganic substance GO:0010035 127 0.026
morphogenesis of embryonic epithelium GO:0016331 4 0.026
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.026
response to organic cyclic compound GO:0014070 204 0.026
cellular response to peptide GO:1901653 59 0.025
cell part morphogenesis GO:0032990 137 0.025
eye photoreceptor cell differentiation GO:0001754 2 0.025
single organismal cell cell adhesion GO:0016337 148 0.025
regulation of rho protein signal transduction GO:0035023 79 0.025
positive regulation of keratinocyte migration GO:0051549 4 0.025
rhythmic behavior GO:0007622 2 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
regulation of cell growth GO:0001558 135 0.025
cellular response to lipid GO:0071396 127 0.025
regulation of cell activation GO:0050865 125 0.024
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.024
internal protein amino acid acetylation GO:0006475 101 0.024
regulation of epithelial cell proliferation GO:0050678 113 0.024
epithelial cell differentiation GO:0030855 141 0.024
cellular protein catabolic process GO:0044257 261 0.024
cation transmembrane transport GO:0098655 238 0.024
cellular response to organonitrogen compound GO:0071417 124 0.023
carboxylic acid biosynthetic process GO:0046394 97 0.023
regeneration GO:0031099 4 0.023
Rat
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 2 0.023
response to nutrient levels GO:0031667 81 0.023
positive regulation of synaptic transmission GO:0050806 4 0.023
hemopoiesis GO:0030097 180 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
brain development GO:0007420 97 0.023
t cell receptor signaling pathway GO:0050852 21 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
lipid localization GO:0010876 106 0.022
mitochondrion organization GO:0007005 156 0.022
cell fate determination GO:0001709 3 0.022
cell activation GO:0001775 213 0.022
regulation of action potential GO:0098900 2 0.022
response to steroid hormone GO:0048545 80 0.022
cellular response to interferon gamma GO:0071346 24 0.022
protein localization to plasma membrane GO:0072659 93 0.022
protein processing GO:0016485 226 0.022
response to peptide hormone GO:0043434 61 0.022
establishment of protein localization to membrane GO:0090150 121 0.022
regulation of endocytosis GO:0030100 72 0.022
primary neural tube formation GO:0014020 3 0.022
negative regulation of cell cycle GO:0045786 193 0.022
negative regulation of growth GO:0045926 97 0.022
neural tube formation GO:0001841 3 0.021
regulation of actin filament based process GO:0032970 141 0.021
cellular response to unfolded protein GO:0034620 16 0.021
multicellular organismal signaling GO:0035637 34 0.021
positive regulation of map kinase activity GO:0043406 80 0.021
tripartite regional subdivision GO:0007351 2 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
response to estrogen GO:0043627 47 0.021
cellular response to insulin stimulus GO:0032869 41 0.021
sodium ion transmembrane transport GO:0035725 59 0.021
leukocyte activation GO:0045321 164 0.021
tube closure GO:0060606 3 0.021
regulation of cellular component movement GO:0051270 334 0.021
intracellular protein transport GO:0006886 270 0.021
Human
cellular response to type i interferon GO:0071357 12 0.021
transmembrane transport GO:0055085 399 0.020
cellular response to interleukin 6 GO:0071354 14 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
positive regulation of proteolysis GO:0045862 142 0.020
organic acid biosynthetic process GO:0016053 97 0.020
positive regulation of growth GO:0045927 58 0.020
myeloid cell homeostasis GO:0002262 34 0.020
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.020
positive regulation of jak stat cascade GO:0046427 35 0.020
b cell activation GO:0042113 33 0.020
regulation of cytokine production GO:0001817 232 0.020
circadian behavior GO:0048512 2 0.020
regulation of meiotic cell cycle GO:0051445 4 0.019
negative regulation of cell motility GO:2000146 104 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.019
associative learning GO:0008306 1 0.019
action potential GO:0001508 34 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
lymphocyte activation GO:0046649 133 0.019
negative regulation of immune response GO:0050777 40 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
cell chemotaxis GO:0060326 112 0.019
regulation of leukocyte activation GO:0002694 115 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
plasma membrane organization GO:0007009 115 0.018
cytoplasmic transport GO:0016482 379 0.018
Human
regulation of keratinocyte migration GO:0051547 4 0.018
receptor transactivation GO:0035624 4 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
cardiac muscle contraction GO:0060048 34 0.018
creatine metabolic process GO:0006600 2 0.018
leukocyte differentiation GO:0002521 98 0.018
positive regulation of cell adhesion GO:0045785 84 0.018
response to other organism GO:0051707 261 0.018
regulation of chemotaxis GO:0050920 74 0.018
mitotic cell cycle process GO:1903047 286 0.018
small molecule biosynthetic process GO:0044283 157 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
response to growth hormone GO:0060416 11 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
response to metal ion GO:0010038 84 0.018
response to hormone GO:0009725 175 0.018
immune response regulating signaling pathway GO:0002764 97 0.017
neurogenesis GO:0022008 169 0.017
establishment of tissue polarity GO:0007164 3 0.017
cellular response to tumor necrosis factor GO:0071356 63 0.017
tissue morphogenesis GO:0048729 96 0.017
cation transport GO:0006812 331 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
cell cell junction organization GO:0045216 69 0.017
response to starvation GO:0042594 59 0.017
wnt signaling pathway GO:0016055 156 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
negative regulation of transferase activity GO:0051348 124 0.017
regulation of secretion GO:0051046 194 0.017
spermatid development GO:0007286 4 0.017
regulation of response to external stimulus GO:0032101 222 0.017
positive regulation of locomotion GO:0040017 186 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
cell cycle phase transition GO:0044770 173 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
alcohol metabolic process GO:0006066 114 0.016
negative regulation of response to wounding GO:1903035 47 0.016
central nervous system development GO:0007417 123 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
epithelial cell proliferation GO:0050673 128 0.016
regulation of protein catabolic process GO:0042176 155 0.016
blastoderm segmentation GO:0007350 2 0.016
cytokinesis GO:0000910 96 0.016
cell junction assembly GO:0034329 67 0.016
negative regulation of cytokine production GO:0001818 82 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
Human
multicellular organismal response to stress GO:0033555 1 0.016
male meiosis GO:0007140 1 0.016
response to tumor necrosis factor GO:0034612 76 0.016
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.016
positive regulation of meiotic cell cycle GO:0051446 2 0.016
negative regulation of map kinase activity GO:0043407 27 0.016
visual behavior GO:0007632 2 0.016
myeloid cell differentiation GO:0030099 117 0.015
positive regulation of transport GO:0051050 336 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
negative regulation of erk1 and erk2 cascade GO:0070373 14 0.015
cartilage development GO:0051216 31 0.015
keratinocyte differentiation GO:0030216 36 0.015
negative regulation of epithelial cell proliferation GO:0050680 48 0.015
intracellular mrna localization GO:0008298 1 0.015
metal ion homeostasis GO:0055065 169 0.015
xenobiotic transport GO:0042908 1 0.015
neural tube closure GO:0001843 3 0.015
regulation of peptidase activity GO:0052547 180 0.015
axis elongation GO:0003401 4 0.015
protein localization to organelle GO:0033365 280 0.015
positive regulation of protein transport GO:0051222 135 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
epidermal cell differentiation GO:0009913 45 0.015
response to endoplasmic reticulum stress GO:0034976 49 0.015
endosomal transport GO:0016197 129 0.015
response to low density lipoprotein particle GO:0055098 4 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
Human
reactive oxygen species biosynthetic process GO:1903409 4 0.015
axon cargo transport GO:0008088 2 0.015
response to biotic stimulus GO:0009607 276 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
glucose homeostasis GO:0042593 31 0.015
cell growth GO:0016049 160 0.015
monocyte activation GO:0042117 3 0.015
thymic t cell selection GO:0045061 2 0.015
organelle fission GO:0048285 149 0.015
lung alveolus development GO:0048286 4 0.014
establishment of planar polarity GO:0001736 3 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.014
peripheral nervous system development GO:0007422 2 0.014
regulation of lipid storage GO:0010883 21 0.014
steroid metabolic process GO:0008202 94 0.014
cellular chemical homeostasis GO:0055082 180 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
negative regulation of myeloid cell differentiation GO:0045638 42 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
covalent chromatin modification GO:0016569 254 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.014
membrane depolarization during cardiac muscle cell action potential GO:0086012 7 0.014
developmental programmed cell death GO:0010623 3 0.014

PTPN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.268
inherited metabolic disorder DOID:655 242 0.257
familial hyperlipidemia DOID:1168 9 0.236
lipid metabolism disorder DOID:3146 26 0.236
musculoskeletal system disease DOID:17 223 0.171
muscular disease DOID:0080000 114 0.111
myopathy DOID:423 104 0.077
heart disease DOID:114 68 0.077
cardiomyopathy DOID:0050700 50 0.077
cardiovascular system disease DOID:1287 106 0.077
muscle tissue disease DOID:66 113 0.077
intrinsic cardiomyopathy DOID:0060036 50 0.064
heart conduction disease DOID:10273 18 0.050
brugada syndrome DOID:0050451 8 0.050
familial hypercholesterolemia DOID:13810 7 0.038
central nervous system disease DOID:331 186 0.030
nervous system disease DOID:863 431 0.030
connective tissue disease DOID:65 109 0.028
dilated cardiomyopathy DOID:12930 32 0.024
bone disease DOID:0080001 88 0.024
sensory system disease DOID:0050155 203 0.020
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015