Homo sapiens

0 known processes

PTPN4

protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)

(Aliases: PTPMEG1,PTPMEG)

PTPN4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
purine containing compound catabolic process GO:0072523 411 0.352
nucleoside phosphate catabolic process GO:1901292 412 0.305
nucleoside catabolic process GO:0009164 408 0.299
glycosyl compound catabolic process GO:1901658 413 0.294
purine nucleotide catabolic process GO:0006195 405 0.238
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.226
ribonucleoside triphosphate catabolic process GO:0009203 391 0.206
purine ribonucleoside metabolic process GO:0046128 437 0.206
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.203
regulation of mapk cascade GO:0043408 262 0.180
purine nucleoside triphosphate catabolic process GO:0009146 392 0.179
purine ribonucleotide catabolic process GO:0009154 404 0.176
purine nucleoside monophosphate catabolic process GO:0009128 158 0.162
nucleotide catabolic process GO:0009166 408 0.155
purine nucleoside catabolic process GO:0006152 398 0.154
nucleoside triphosphate metabolic process GO:0009141 422 0.147
organophosphate catabolic process GO:0046434 430 0.144
ribonucleotide catabolic process GO:0009261 405 0.140
purine nucleoside triphosphate metabolic process GO:0009144 412 0.131
purine ribonucleoside catabolic process GO:0046130 398 0.127
mapk cascade GO:0000165 288 0.124
cellular ketone metabolic process GO:0042180 80 0.123
ribonucleoside triphosphate metabolic process GO:0009199 412 0.120
apoptotic signaling pathway GO:0097190 268 0.106
atp metabolic process GO:0046034 176 0.097
ribonucleoside monophosphate catabolic process GO:0009158 158 0.096
chromatin organization GO:0006325 351 0.093
cell projection organization GO:0030030 252 0.089
regulation of cell cycle process GO:0010564 266 0.086
ribonucleoside monophosphate metabolic process GO:0009161 187 0.086
glial cell migration GO:0008347 4 0.083
regulation of jnk cascade GO:0046328 73 0.083
nucleoside monophosphate metabolic process GO:0009123 191 0.082
ribonucleoside catabolic process GO:0042454 406 0.081
signal transduction by phosphorylation GO:0023014 297 0.081
ras protein signal transduction GO:0007265 73 0.081
nucleoside triphosphate catabolic process GO:0009143 394 0.080
positive regulation of cellular catabolic process GO:0031331 284 0.078
response to other organism GO:0051707 261 0.076
chromatin modification GO:0016568 298 0.075
stress activated mapk cascade GO:0051403 93 0.072
system process GO:0003008 349 0.071
determination of adult lifespan GO:0008340 2 0.070
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.069
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.069
regulation of cell cycle GO:0051726 393 0.068
Human
female gamete generation GO:0007292 2 0.068
nervous system development GO:0007399 293 0.066
locomotory behavior GO:0007626 1 0.064
negative regulation of cell cycle process GO:0010948 121 0.063
dna replication GO:0006260 116 0.062
jnk cascade GO:0007254 80 0.062
defense response GO:0006952 315 0.060
nucleoside monophosphate catabolic process GO:0009125 159 0.059
stress activated protein kinase signaling cascade GO:0031098 94 0.057
positive regulation of phosphorylation GO:0042327 394 0.057
positive regulation of transport GO:0051050 336 0.056
intrinsic apoptotic signaling pathway GO:0097193 127 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.055
post embryonic development GO:0009791 2 0.054
blastoderm segmentation GO:0007350 2 0.054
purine nucleoside monophosphate metabolic process GO:0009126 186 0.054
positive regulation of catabolic process GO:0009896 310 0.054
regulation of cellular response to stress GO:0080135 244 0.052
cellular response to endogenous stimulus GO:0071495 336 0.049
mitotic cell cycle phase transition GO:0044772 162 0.048
negative regulation of cell cycle GO:0045786 193 0.047
Human
response to biotic stimulus GO:0009607 276 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.046
positive regulation of transferase activity GO:0051347 227 0.045
cell development GO:0048468 328 0.045
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.044
small gtpase mediated signal transduction GO:0007264 78 0.044
response to oxygen containing compound GO:1901700 369 0.043
membrane organization GO:0061024 292 0.043
cellular response to dna damage stimulus GO:0006974 379 0.043
taxis GO:0042330 157 0.043
hemopoiesis GO:0030097 180 0.043
positive regulation of developmental process GO:0051094 314 0.042
cellular response to nitrogen compound GO:1901699 144 0.042
cell cycle checkpoint GO:0000075 117 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.042
negative regulation of mitotic cell cycle GO:0045930 102 0.042
Human
regulation of cytokine production GO:0001817 232 0.042
secretion GO:0046903 254 0.041
negative regulation of catalytic activity GO:0043086 335 0.040
cell cycle phase transition GO:0044770 173 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
cellular response to oxygen containing compound GO:1901701 276 0.039
cellular component morphogenesis GO:0032989 314 0.039
rho protein signal transduction GO:0007266 26 0.038
microtubule based process GO:0007017 210 0.038
multicellular organismal aging GO:0010259 3 0.038
cell division GO:0051301 168 0.038
regulation of stress activated mapk cascade GO:0032872 84 0.038
negative regulation of apoptotic process GO:0043066 316 0.038
anatomical structure homeostasis GO:0060249 100 0.038
oogenesis GO:0048477 2 0.037
cellular lipid metabolic process GO:0044255 303 0.036
cellular response to organic cyclic compound GO:0071407 127 0.036
cellular amine metabolic process GO:0044106 41 0.035
response to external biotic stimulus GO:0043207 261 0.035
negative regulation of multicellular organismal process GO:0051241 317 0.035
mitotic cell cycle GO:0000278 326 0.035
Human
central nervous system development GO:0007417 123 0.035
peptidyl lysine modification GO:0018205 144 0.035
neuron projection development GO:0031175 106 0.034
reactive oxygen species metabolic process GO:0072593 75 0.034
regulation of transferase activity GO:0051338 355 0.034
regulation of cell cycle phase transition GO:1901987 126 0.034
cellular homeostasis GO:0019725 196 0.034
oxidation reduction process GO:0055114 396 0.034
regulation of protein transport GO:0051223 213 0.033
Human
transmembrane transport GO:0055085 399 0.033
Human
regulation of kinase activity GO:0043549 314 0.033
regulation of dna metabolic process GO:0051052 153 0.033
biological adhesion GO:0022610 331 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
Human
protein catabolic process GO:0030163 325 0.032
Human
negative regulation of protein metabolic process GO:0051248 391 0.032
Human
lipid metabolic process GO:0006629 381 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
response to inorganic substance GO:0010035 127 0.032
regulation of response to external stimulus GO:0032101 222 0.031
innate immune response GO:0045087 178 0.031
chemical homeostasis GO:0048878 306 0.031
Human
segmentation GO:0035282 4 0.031
cellular amino acid metabolic process GO:0006520 116 0.031
interspecies interaction between organisms GO:0044419 156 0.031
secretion by cell GO:0032940 226 0.031
cell cell signaling GO:0007267 155 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.030
cell morphogenesis GO:0000902 296 0.030
cytokine production GO:0001816 247 0.030
negative regulation of hydrolase activity GO:0051346 182 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
response to oxidative stress GO:0006979 121 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
hindbrain development GO:0030902 3 0.029
regulation of transcription by chromatin organization GO:0034401 1 0.029
negative regulation of programmed cell death GO:0043069 321 0.028
protein acylation GO:0043543 138 0.028
nucleosome organization GO:0034728 66 0.028
response to radiation GO:0009314 151 0.028
spermatid differentiation GO:0048515 4 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
regulation of reactive oxygen species metabolic process GO:2000377 41 0.028
negative regulation of cell death GO:0060548 345 0.028
amine metabolic process GO:0009308 44 0.027
cellular chemical homeostasis GO:0055082 180 0.027
positive regulation of dna metabolic process GO:0051054 73 0.027
cellular response to external stimulus GO:0071496 111 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
Human
associative learning GO:0008306 1 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
positive regulation of cell cycle process GO:0090068 106 0.026
regulation of proteolysis GO:0030162 293 0.026
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.026
neuron remodeling GO:0016322 2 0.026
regulation of cell differentiation GO:0045595 393 0.026
protein maturation GO:0051604 233 0.026
Human
cellular macromolecule catabolic process GO:0044265 380 0.025
ion homeostasis GO:0050801 230 0.025
Human
myeloid cell differentiation GO:0030099 117 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
single organism cellular localization GO:1902580 332 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
epithelial cell differentiation GO:0030855 141 0.024
covalent chromatin modification GO:0016569 254 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.024
neuromuscular junction development GO:0007528 3 0.024
dna conformation change GO:0071103 113 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
cilium morphogenesis GO:0060271 75 0.024
intracellular protein transport GO:0006886 270 0.024
Human
response to organic cyclic compound GO:0014070 204 0.024
atp catabolic process GO:0006200 157 0.024
regulation of secretion by cell GO:1903530 177 0.024
response to nitrogen compound GO:1901698 184 0.024
calcium ion homeostasis GO:0055074 122 0.024
adult locomotory behavior GO:0008344 1 0.024
mitochondrion organization GO:0007005 156 0.024
positive regulation of kinase activity GO:0033674 204 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
neurogenesis GO:0022008 169 0.024
embryonic placenta development GO:0001892 1 0.023
negative regulation of developmental process GO:0051093 247 0.023
cellular ion homeostasis GO:0006873 168 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
meiosis i GO:0007127 4 0.023
generation of neurons GO:0048699 152 0.023
multi organism cellular process GO:0044764 156 0.023
cerebellum development GO:0021549 2 0.023
gtp catabolic process GO:0006184 237 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
cilium assembly GO:0042384 63 0.023
cellular calcium ion homeostasis GO:0006874 117 0.022
regulation of cell migration GO:0030334 289 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.022
leukocyte differentiation GO:0002521 98 0.022
phospholipid metabolic process GO:0006644 99 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
dna packaging GO:0006323 77 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
immune system development GO:0002520 195 0.022
regulation of protein localization GO:0032880 296 0.022
Human
motor neuron axon guidance GO:0008045 2 0.022
regulation of protein processing GO:0070613 150 0.022
Human
metencephalon development GO:0022037 2 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
regulation of dna replication GO:0006275 68 0.022
maintenance of location GO:0051235 112 0.022
spindle elongation GO:0051231 4 0.021
regulation of chromosome organization GO:0033044 103 0.021
cell substrate adhesion GO:0031589 132 0.021
single organism reproductive process GO:0044702 98 0.021
chemotaxis GO:0006935 157 0.021
cellular protein catabolic process GO:0044257 261 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
vesicle mediated transport GO:0016192 371 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
positive regulation of organelle organization GO:0010638 195 0.021
growth GO:0040007 202 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
protein localization to organelle GO:0033365 280 0.021
positive regulation of cell cycle GO:0045787 140 0.021
microtubule cytoskeleton organization GO:0000226 176 0.020
reproductive process GO:0022414 106 0.020
positive regulation of cell motility GO:2000147 177 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
cardiovascular system development GO:0072358 262 0.020
Human
response to light stimulus GO:0009416 87 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
positive regulation of protein transport GO:0051222 135 0.020
dephosphorylation GO:0016311 209 0.019
Human Mouse Rat
brain development GO:0007420 97 0.019
endothelial cell migration GO:0043542 86 0.019
compound eye development GO:0048749 1 0.019
regulation of cellular component movement GO:0051270 334 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
dna repair GO:0006281 198 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
cell adhesion GO:0007155 325 0.019
lymphocyte homeostasis GO:0002260 4 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
regulation of gtpase activity GO:0043087 180 0.019
reactive nitrogen species metabolic process GO:2001057 3 0.019
internal peptidyl lysine acetylation GO:0018393 97 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
negative regulation of cell cycle phase transition GO:1901988 89 0.018
development of primary male sexual characteristics GO:0046546 23 0.018
metal ion homeostasis GO:0055065 169 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
mitotic spindle elongation GO:0000022 4 0.018
chromosome segregation GO:0007059 114 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
response to growth factor GO:0070848 205 0.018
gtp metabolic process GO:0046039 239 0.018
immune response GO:0006955 307 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
jak stat cascade GO:0007259 46 0.018
metal ion transport GO:0030001 272 0.018
Human
organelle assembly GO:0070925 176 0.018
positive regulation of telomere maintenance GO:0032206 4 0.018
cellular response to abiotic stimulus GO:0071214 117 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
actin filament based movement GO:0030048 17 0.018
neuron development GO:0048666 113 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
single organism membrane organization GO:0044802 268 0.018
protein acetylation GO:0006473 116 0.018
regulation of secretion GO:0051046 194 0.018
positive regulation of meiotic cell cycle GO:0051446 2 0.017
negative regulation of protein processing GO:0010955 142 0.017
Human
rhythmic behavior GO:0007622 2 0.017
positive regulation of response to external stimulus GO:0032103 88 0.017
response to virus GO:0009615 126 0.017
rac protein signal transduction GO:0016601 12 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
negative regulation of transport GO:0051051 176 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
negative regulation of immune system process GO:0002683 136 0.017
single organism cell adhesion GO:0098602 179 0.017
regulation of multi organism process GO:0043900 157 0.017
cell junction assembly GO:0034329 67 0.017
glycerolipid metabolic process GO:0046486 107 0.017
regulation of protein catabolic process GO:0042176 155 0.017
Human
regulation of nucleotide metabolic process GO:0006140 269 0.017
cellular response to lipid GO:0071396 127 0.016
response to abiotic stimulus GO:0009628 336 0.016
rna splicing GO:0008380 131 0.016
lipid biosynthetic process GO:0008610 177 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
cellular metal ion homeostasis GO:0006875 146 0.016
spermatid development GO:0007286 4 0.016
regulation of protein secretion GO:0050708 86 0.016
behavior GO:0007610 112 0.016
actin filament based process GO:0030029 224 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
negative regulation of organelle organization GO:0010639 126 0.016
leukocyte activation GO:0045321 164 0.016
organelle localization GO:0051640 84 0.016
cellular cation homeostasis GO:0030003 163 0.016
histone h3 acetylation GO:0043966 45 0.015
positive regulation of immune system process GO:0002684 283 0.015
glycerophospholipid metabolic process GO:0006650 84 0.015
endocytosis GO:0006897 159 0.015
mitotic nuclear division GO:0007067 119 0.015
defense response to fungus GO:0050832 4 0.015
regulation of locomotion GO:0040012 329 0.015
signal transduction in response to dna damage GO:0042770 57 0.015
signal transduction by p53 class mediator GO:0072331 72 0.015
replication fork processing GO:0031297 13 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
regulation of cell motility GO:2000145 299 0.015
immune effector process GO:0002252 159 0.015
protein ubiquitination GO:0016567 314 0.015
viral life cycle GO:0019058 132 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
histone modification GO:0016570 251 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
regulation of cell growth GO:0001558 135 0.015
response to lipid GO:0033993 206 0.015
meiotic chromosome segregation GO:0045132 4 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
nucleosome assembly GO:0006334 50 0.015
lipid localization GO:0010876 106 0.015
cation transport GO:0006812 331 0.015
Human
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.014
autophagy GO:0006914 88 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
cellular protein complex assembly GO:0043623 188 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
Human
protein processing GO:0016485 226 0.014
Human
response to bacterium GO:0009617 144 0.014
regulation of cell development GO:0060284 161 0.014
protein dna complex assembly GO:0065004 64 0.014
mitotic cell cycle process GO:1903047 286 0.014
ion transmembrane transport GO:0034220 338 0.014
Human
positive regulation of gtp catabolic process GO:0033126 166 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
cation homeostasis GO:0055080 189 0.014
dna dependent dna replication GO:0006261 44 0.014
cell projection assembly GO:0030031 126 0.014
hair follicle morphogenesis GO:0031069 2 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
protein targeting GO:0006605 187 0.014
organelle fission GO:0048285 149 0.014
positive regulation of dna replication GO:0045740 35 0.014
neurotransmitter secretion GO:0007269 4 0.014
male gonad development GO:0008584 23 0.014
wnt signaling pathway GO:0016055 156 0.014
anion transport GO:0006820 161 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
long term memory GO:0007616 2 0.014
rap protein signal transduction GO:0032486 7 0.014
dna replication independent nucleosome assembly GO:0006336 27 0.014
inner ear morphogenesis GO:0042472 4 0.014
t cell differentiation in thymus GO:0033077 4 0.014
actin mediated cell contraction GO:0070252 12 0.014
stem cell division GO:0017145 2 0.014
regulation of intracellular transport GO:0032386 195 0.014
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.014
oocyte development GO:0048599 1 0.013
cellular response to oxidative stress GO:0034599 85 0.013
neuron differentiation GO:0030182 138 0.013
regulation of protein maturation GO:1903317 150 0.013
Human
cytoplasmic transport GO:0016482 379 0.013
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
positive regulation of homeostatic process GO:0032846 47 0.013
positive regulation of cytokine production GO:0001819 167 0.013
nerve development GO:0021675 4 0.013
viral process GO:0016032 146 0.013
regulation of growth GO:0040008 165 0.013
cell part morphogenesis GO:0032990 137 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
tissue morphogenesis GO:0048729 96 0.013
cell type specific apoptotic process GO:0097285 125 0.013
memory GO:0007613 3 0.013
cell growth GO:0016049 160 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
regulation of defense response GO:0031347 154 0.013
cellular response to radiation GO:0071478 65 0.013
rna processing GO:0006396 255 0.013
response to metal ion GO:0010038 84 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
negative regulation of protein maturation GO:1903318 142 0.013
Human
regulation of telomere maintenance GO:0032204 13 0.013
sequestering of calcium ion GO:0051208 17 0.013
double strand break repair GO:0006302 101 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
developmental process involved in reproduction GO:0003006 66 0.012
positive regulation of locomotion GO:0040017 186 0.012
response to fungus GO:0009620 4 0.012
translation GO:0006412 132 0.012
regulation of protein kinase activity GO:0045859 289 0.012
embryo development GO:0009790 123 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of dephosphorylation GO:0035303 96 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of cell adhesion GO:0030155 166 0.012
cellular response to nutrient levels GO:0031669 69 0.012
histone acetylation GO:0016573 93 0.012
regulation of mitosis GO:0007088 63 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
somitogenesis GO:0001756 2 0.012
neuroblast proliferation GO:0007405 4 0.012
neurological system process GO:0050877 163 0.012
neural nucleus development GO:0048857 47 0.012
cellular response to starvation GO:0009267 58 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
primary neural tube formation GO:0014020 3 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
regulation of leukocyte differentiation GO:1902105 61 0.012
cell projection morphogenesis GO:0048858 129 0.012
regulation of endothelial cell migration GO:0010594 67 0.012
sequestering of metal ion GO:0051238 24 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of phosphatase activity GO:0010921 81 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
regulation of nervous system development GO:0051960 88 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
negative regulation of protein modification process GO:0031400 200 0.012
head development GO:0060322 108 0.012
positive regulation of cell death GO:0010942 263 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
protein localization to membrane GO:0072657 160 0.012
regeneration GO:0031099 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
protein secretion GO:0009306 98 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
chromatin remodeling GO:0006338 55 0.011
epithelium migration GO:0090132 119 0.011
protein dna complex subunit organization GO:0071824 80 0.011
visual behavior GO:0007632 2 0.011
regulation of innate immune response GO:0045088 97 0.011
protein homooligomerization GO:0051260 100 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
epithelial cell development GO:0002064 34 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
Human
nuclear export GO:0051168 69 0.011
Human
phosphatidylinositol metabolic process GO:0046488 53 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
positive regulation of secretion GO:0051047 116 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
dna recombination GO:0006310 77 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
actin filament organization GO:0007015 128 0.011
lymphocyte activation GO:0046649 133 0.011
dna damage checkpoint GO:0000077 68 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
cilium organization GO:0044782 68 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
reproductive structure development GO:0048608 55 0.011
cytokine biosynthetic process GO:0042089 37 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
sensory perception GO:0007600 103 0.011
regulation of lymphocyte activation GO:0051249 103 0.011

PTPN4 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
immune system disease DOID:2914 155 0.015
disease of metabolism DOID:0014667 295 0.015
organ system cancer DOID:0050686 164 0.013
musculoskeletal system disease DOID:17 223 0.012
cardiovascular system disease DOID:1287 106 0.012
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011
inherited metabolic disorder DOID:655 242 0.011
neurodegenerative disease DOID:1289 102 0.011