Homo sapiens

24 known processes

ETHE1

ethylmalonic encephalopathy 1

(Aliases: HSCO,YF13H12)

ETHE1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.161
ras protein signal transduction GO:0007265 73 0.093
gtp catabolic process GO:0006184 237 0.081
cellular amino acid metabolic process GO:0006520 116 0.073
nucleoside phosphate catabolic process GO:1901292 412 0.070
ribonucleoside catabolic process GO:0042454 406 0.070
positive regulation of nucleoside metabolic process GO:0045979 186 0.066
glycosyl compound catabolic process GO:1901658 413 0.056
regulation of cellular component biogenesis GO:0044087 281 0.055
glutathione metabolic process GO:0006749 20 0.051
ribonucleotide catabolic process GO:0009261 405 0.051
membrane organization GO:0061024 292 0.048
nucleotide catabolic process GO:0009166 408 0.047
cofactor metabolic process GO:0051186 87 0.047
nucleoside catabolic process GO:0009164 408 0.046
purine nucleoside triphosphate metabolic process GO:0009144 412 0.045
vesicle mediated transport GO:0016192 371 0.045
purine containing compound catabolic process GO:0072523 411 0.044
determination of adult lifespan GO:0008340 2 0.044
negative regulation of protein metabolic process GO:0051248 391 0.044
gtp metabolic process GO:0046039 239 0.041
nucleoside triphosphate metabolic process GO:0009141 422 0.041
small gtpase mediated signal transduction GO:0007264 78 0.040
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
organophosphate catabolic process GO:0046434 430 0.040
guanosine containing compound metabolic process GO:1901068 244 0.040
regulation of nucleotide catabolic process GO:0030811 205 0.039
regeneration GO:0031099 4 0.039
multicellular organismal aging GO:0010259 3 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
positive regulation of gtp catabolic process GO:0033126 166 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.037
positive regulation of nucleotide metabolic process GO:0045981 230 0.037
positive regulation of hydrolase activity GO:0051345 331 0.036
cytoplasmic transport GO:0016482 379 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
inorganic cation transmembrane transport GO:0098662 194 0.036
regulation of gtpase activity GO:0043087 180 0.036
guanosine containing compound catabolic process GO:1901069 239 0.035
positive regulation of gtpase activity GO:0043547 166 0.035
negative regulation of cellular component organization GO:0051129 235 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
defense response GO:0006952 315 0.034
carbohydrate metabolic process GO:0005975 207 0.034
cell adhesion GO:0007155 325 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
immune response GO:0006955 307 0.034
response to biotic stimulus GO:0009607 276 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
negative regulation of catalytic activity GO:0043086 335 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
inorganic ion transmembrane transport GO:0098660 231 0.032
cellular response to dna damage stimulus GO:0006974 379 0.032
regulation of transferase activity GO:0051338 355 0.032
purine nucleotide catabolic process GO:0006195 405 0.031
hemopoiesis GO:0030097 180 0.031
apoptotic signaling pathway GO:0097190 268 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.030
post embryonic development GO:0009791 2 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
ion transmembrane transport GO:0034220 338 0.030
positive regulation of nucleotide catabolic process GO:0030813 185 0.030
negative regulation of apoptotic process GO:0043066 316 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
amine metabolic process GO:0009308 44 0.029
cellular lipid metabolic process GO:0044255 303 0.029
biological adhesion GO:0022610 331 0.029
cellular ketone metabolic process GO:0042180 80 0.029
positive regulation of immune system process GO:0002684 283 0.029
purine nucleoside catabolic process GO:0006152 398 0.029
locomotory behavior GO:0007626 1 0.029
coenzyme metabolic process GO:0006732 65 0.028
positive regulation of catabolic process GO:0009896 310 0.028
regulation of protein localization GO:0032880 296 0.028
cellular amine metabolic process GO:0044106 41 0.028
nervous system development GO:0007399 293 0.027
regulation of cell migration GO:0030334 289 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
regulation of proteolysis GO:0030162 293 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
sulfur compound metabolic process GO:0006790 101 0.027
cellular protein complex assembly GO:0043623 188 0.027
response to external biotic stimulus GO:0043207 261 0.027
metal ion transport GO:0030001 272 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
regulation of cellular response to stress GO:0080135 244 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
secretion by cell GO:0032940 226 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
regulation of gtp catabolic process GO:0033124 180 0.025
positive regulation of locomotion GO:0040017 186 0.025
single organism cell adhesion GO:0098602 179 0.025
epithelium development GO:0060429 227 0.024
response to oxygen containing compound GO:1901700 369 0.024
negative regulation of cell death GO:0060548 345 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
negative regulation of transport GO:0051051 176 0.024
fatty acid metabolic process GO:0006631 115 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
lipid metabolic process GO:0006629 381 0.024
positive regulation of ras gtpase activity GO:0032320 117 0.023
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
regulation of kinase activity GO:0043549 314 0.023
single organism membrane organization GO:0044802 268 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
cellular response to endogenous stimulus GO:0071495 336 0.023
response to abiotic stimulus GO:0009628 336 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
cation transport GO:0006812 331 0.023
cellular component morphogenesis GO:0032989 314 0.023
cell development GO:0048468 328 0.023
negative regulation of programmed cell death GO:0043069 321 0.022
carboxylic acid biosynthetic process GO:0046394 97 0.022
immune system development GO:0002520 195 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
regulation of ras gtpase activity GO:0032318 128 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.022
response to nutrient levels GO:0031667 81 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
small molecule biosynthetic process GO:0044283 157 0.022
response to lipid GO:0033993 206 0.022
protein maturation GO:0051604 233 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
response to wounding GO:0009611 168 0.020
regulation of immune response GO:0050776 201 0.020
endosomal transport GO:0016197 129 0.020
innate immune response GO:0045087 178 0.020
calcium ion transport GO:0006816 147 0.020
oogenesis GO:0048477 2 0.020
cellular protein catabolic process GO:0044257 261 0.020
regulation of small gtpase mediated signal transduction GO:0051056 156 0.020
positive regulation of cellular component movement GO:0051272 181 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
cytokine production GO:0001816 247 0.020
response to oxidative stress GO:0006979 121 0.020
adult locomotory behavior GO:0008344 1 0.020
divalent inorganic cation transport GO:0072511 158 0.020
regulation of actin filament based process GO:0032970 141 0.020
cation transmembrane transport GO:0098655 238 0.020
establishment of protein localization to membrane GO:0090150 121 0.020
cellular response to lipid GO:0071396 127 0.020
vesicle organization GO:0016050 62 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
positive regulation of transport GO:0051050 336 0.019
female gamete generation GO:0007292 2 0.019
transmembrane transport GO:0055085 399 0.019
cell projection organization GO:0030030 252 0.019
regulation of cellular component movement GO:0051270 334 0.019
actin cytoskeleton organization GO:0030036 207 0.019
positive regulation of kinase activity GO:0033674 204 0.019
endothelial cell migration GO:0043542 86 0.019
regulation of protein transport GO:0051223 213 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.018
microtubule based process GO:0007017 210 0.018
response to organic cyclic compound GO:0014070 204 0.018
actin filament based process GO:0030029 224 0.018
rho protein signal transduction GO:0007266 26 0.018
negative regulation of protein modification process GO:0031400 200 0.018
regulation of cell motility GO:2000145 299 0.018
regulation of transmembrane transport GO:0034762 139 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
embryonic hemopoiesis GO:0035162 4 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
cell morphogenesis GO:0000902 296 0.018
regulation of cytokine production GO:0001817 232 0.018
negative regulation of organelle organization GO:0010639 126 0.018
protein localization to membrane GO:0072657 160 0.018
segmentation GO:0035282 4 0.018
regulation of protein kinase activity GO:0045859 289 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
system process GO:0003008 349 0.017
regulation of ion transport GO:0043269 189 0.017
protein localization to plasma membrane GO:0072659 93 0.017
positive regulation of cell migration GO:0030335 172 0.017
single organism cellular localization GO:1902580 332 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
response to hormone GO:0009725 175 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of locomotion GO:0040012 329 0.017
regulation of response to external stimulus GO:0032101 222 0.017
interspecies interaction between organisms GO:0044419 156 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
epithelial cell migration GO:0010631 119 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
somatic muscle development GO:0007525 1 0.016
protein processing GO:0016485 226 0.016
regulation of secretion GO:0051046 194 0.016
regulation of rho gtpase activity GO:0032319 66 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
positive regulation of organelle organization GO:0010638 195 0.016
viral life cycle GO:0019058 132 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.015
response to other organism GO:0051707 261 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
divalent metal ion transport GO:0070838 152 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
response to cytokine GO:0034097 232 0.015
protein catabolic process GO:0030163 325 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
positive regulation of transferase activity GO:0051347 227 0.015
regulation of cell cycle GO:0051726 393 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
mapk cascade GO:0000165 288 0.015
dna recombination GO:0006310 77 0.015
nitrogen compound transport GO:0071705 191 0.015
epithelial cell differentiation GO:0030855 141 0.015
response to bacterium GO:0009617 144 0.015
regulation of ion transmembrane transport GO:0034765 132 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
endomembrane system organization GO:0010256 196 0.015
regulation of multi organism process GO:0043900 157 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.014
organic acid biosynthetic process GO:0016053 97 0.014
positive regulation of immune response GO:0050778 159 0.014
regulation of cell differentiation GO:0045595 393 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
cellular cation homeostasis GO:0030003 163 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
positive regulation of cell motility GO:2000147 177 0.014
plasma membrane organization GO:0007009 115 0.014
mitochondrion organization GO:0007005 156 0.014
mitotic cell cycle process GO:1903047 286 0.014
endocytosis GO:0006897 159 0.014
cell chemotaxis GO:0060326 112 0.014
regulation of actin cytoskeleton organization GO:0032956 116 0.014
cell growth GO:0016049 160 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
monocarboxylic acid biosynthetic process GO:0072330 67 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
regulation of defense response GO:0031347 154 0.014
cellular ion homeostasis GO:0006873 168 0.014
dna repair GO:0006281 198 0.014
regulation of cell cycle process GO:0010564 266 0.014
response to nitrogen compound GO:1901698 184 0.014
regulation of secretion by cell GO:1903530 177 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
positive regulation of developmental process GO:0051094 314 0.014
defense response to other organism GO:0098542 129 0.013
regulation of jnk cascade GO:0046328 73 0.013
cellular response to nutrient levels GO:0031669 69 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
peptide metabolic process GO:0006518 51 0.013
taxis GO:0042330 157 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
multi organism cellular process GO:0044764 156 0.013
neuromuscular junction development GO:0007528 3 0.013
establishment of protein localization to plasma membrane GO:0090002 68 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
cytokine mediated signaling pathway GO:0019221 109 0.013
negative regulation of transferase activity GO:0051348 124 0.013
sequestering of calcium ion GO:0051208 17 0.013
response to inorganic substance GO:0010035 127 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
positive regulation of cell death GO:0010942 263 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
organelle assembly GO:0070925 176 0.013
neuroblast proliferation GO:0007405 4 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
viral process GO:0016032 146 0.013
chemical homeostasis GO:0048878 306 0.013
secretion GO:0046903 254 0.013
neurogenesis GO:0022008 169 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of dna metabolic process GO:0051052 153 0.012
response to axon injury GO:0048678 1 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
memory GO:0007613 3 0.012
motor neuron axon guidance GO:0008045 2 0.012
response to organonitrogen compound GO:0010243 156 0.012
intracellular protein transport GO:0006886 270 0.012
positive regulation of lymphocyte activation GO:0051251 73 0.012
sequestering of metal ion GO:0051238 24 0.012
circulatory system development GO:0072359 262 0.012
protein localization to organelle GO:0033365 280 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
regulation of calcium ion transport GO:0051924 79 0.012
response to fungus GO:0009620 4 0.012
rhythmic behavior GO:0007622 2 0.012
regulation of homeostatic process GO:0032844 121 0.012
cellular chemical homeostasis GO:0055082 180 0.012
actin filament organization GO:0007015 128 0.012
icosanoid metabolic process GO:0006690 35 0.012
protein oligomerization GO:0051259 173 0.012
myeloid cell differentiation GO:0030099 117 0.012
regulation of cell morphogenesis GO:0022604 153 0.011
compound eye development GO:0048749 1 0.011
generation of neurons GO:0048699 152 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
regulation of transmembrane transporter activity GO:0022898 74 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
actin polymerization or depolymerization GO:0008154 56 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
protein targeting GO:0006605 187 0.011
regulation of peptidase activity GO:0052547 180 0.011
chemotaxis GO:0006935 157 0.011
dephosphorylation GO:0016311 209 0.011
regulation of cell adhesion GO:0030155 166 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
cellular response to glucocorticoid stimulus GO:0071385 4 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
negative regulation of cytokine production GO:0001818 82 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
head development GO:0060322 108 0.011
monosaccharide metabolic process GO:0005996 74 0.011
regulation of mapk cascade GO:0043408 262 0.011
epithelial cell proliferation GO:0050673 128 0.011
negative regulation of cell cycle GO:0045786 193 0.011
epithelium migration GO:0090132 119 0.011
neuron projection regeneration GO:0031102 1 0.011
protein ubiquitination GO:0016567 314 0.011
blastocyst development GO:0001824 3 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
angiogenesis GO:0001525 147 0.011
response to lipopolysaccharide GO:0032496 70 0.011
negative regulation of protein maturation GO:1903318 142 0.011
tissue regeneration GO:0042246 3 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
protein acylation GO:0043543 138 0.011
metal ion homeostasis GO:0055065 169 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of metal ion transport GO:0010959 120 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
negative regulation of jun kinase activity GO:0043508 4 0.010
rna interference GO:0016246 4 0.010
positive regulation of cell projection organization GO:0031346 64 0.010
immune effector process GO:0002252 159 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
peptidyl lysine modification GO:0018205 144 0.010
nuclear transport GO:0051169 179 0.010
positive regulation of innate immune response GO:0045089 79 0.010
cell division GO:0051301 168 0.010
circadian behavior GO:0048512 2 0.010
cellular response to external stimulus GO:0071496 111 0.010
tissue migration GO:0090130 119 0.010
leukocyte differentiation GO:0002521 98 0.010
wnt signaling pathway GO:0016055 156 0.010
protein autophosphorylation GO:0046777 123 0.010
regulation of response to wounding GO:1903034 101 0.010
carbohydrate catabolic process GO:0016052 36 0.010

ETHE1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035
disease of metabolism DOID:0014667 295 0.031
inherited metabolic disorder DOID:655 242 0.022
immune system disease DOID:2914 155 0.012
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
brain disease DOID:936 73 0.011