Homo sapiens

79 known processes

EIF2C1

eukaryotic translation initiation factor 2C, 1

(Aliases: EIF2C,DKFZp686M13167,AGO1,GERP95,Q99)

EIF2C1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
production of mirnas involved in gene silencing by mirna GO:0035196 12 1.000
Human Fly
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 1.000
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 1.000
positive regulation of mrna catabolic process GO:0061014 10 1.000
gene silencing by mirna GO:0035195 23 1.000
dsrna fragmentation GO:0031050 13 1.000
Human Fly
production of small rna involved in gene silencing by rna GO:0070918 13 1.000
Human Fly
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.998
production of sirna involved in rna interference GO:0030422 3 0.998
Fly
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.998
regulation of mrna catabolic process GO:0061013 13 0.997
cellular response to dsrna GO:0071359 19 0.990
Human Fly
rna phosphodiester bond hydrolysis GO:0090501 35 0.989
Human
targeting of mrna for destruction involved in rna interference GO:0030423 3 0.986
Fly
positive regulation of mrna 3 end processing GO:0031442 12 0.986
rna catabolic process GO:0006401 71 0.963
mrna metabolic process GO:0016071 175 0.958
mrna cleavage involved in gene silencing by mirna GO:0035279 2 0.951
Human Fly
posttranscriptional gene silencing GO:0016441 25 0.944
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.938
pre mirna processing GO:0031054 8 0.929
Human
negative regulation of translation involved in gene silencing by mirna GO:0035278 6 0.925
cell differentiation in spinal cord GO:0021515 1 0.916
regulation of translation ncrna mediated GO:0045974 6 0.915
gene silencing by rna GO:0031047 26 0.915
mrna catabolic process GO:0006402 56 0.908
translation GO:0006412 132 0.906
regulation of translation GO:0006417 89 0.886
nerve development GO:0021675 4 0.875
regulation of gene silencing by rna GO:0060966 6 0.862
negative regulation of translation ncrna mediated GO:0040033 6 0.850
rna processing GO:0006396 255 0.841
Human Fly
gene silencing GO:0016458 49 0.838
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.830
Human Fly
positive regulation of mrna processing GO:0050685 17 0.827
posttranscriptional gene silencing by rna GO:0035194 25 0.819
response to dsrna GO:0043331 25 0.818
Human Fly
negative regulation of translational initiation GO:0045947 7 0.801
Human
translational initiation GO:0006413 48 0.798
Human
cellular response to nitrogen compound GO:1901699 144 0.797
Human Fly
negative regulation of glial cell proliferation GO:0060253 2 0.791
regulation of mrna 3 end processing GO:0031440 12 0.790
mrna processing GO:0006397 133 0.787
Human Fly
post embryonic development GO:0009791 2 0.785
cellular macromolecule catabolic process GO:0044265 380 0.784
associative learning GO:0008306 1 0.780
Fly
epidermis morphogenesis GO:0048730 3 0.771
ncrna metabolic process GO:0034660 108 0.766
Human Mouse
positive regulation of mrna metabolic process GO:1903313 19 0.751
ncrna processing GO:0034470 83 0.750
Human
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.734
regulation of odontogenesis GO:0042481 4 0.719
regulation of tooth mineralization GO:0070170 3 0.714
determination of adult lifespan GO:0008340 2 0.683
nuclear transcribed mrna catabolic process GO:0000956 48 0.681
cellular response to organic cyclic compound GO:0071407 127 0.674
Human Fly
negative regulation of protein metabolic process GO:0051248 391 0.624
blastoderm segmentation GO:0007350 2 0.613
Fly
rna 3 end processing GO:0031123 35 0.613
regulation of stem cell proliferation GO:0072091 15 0.608
Human
multicellular organismal aging GO:0010259 3 0.598
response to organic cyclic compound GO:0014070 204 0.570
Human Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.548
intestinal epithelial cell differentiation GO:0060575 3 0.506
ribonucleoprotein complex biogenesis GO:0022613 116 0.459
Fly
regulation of gene expression epigenetic GO:0040029 73 0.452
olfactory bulb development GO:0021772 5 0.411
regulation of neurological system process GO:0031644 6 0.353
Fly
regulation of mrna metabolic process GO:1903311 53 0.343
small rna loading onto risc GO:0070922 3 0.336
system process GO:0003008 349 0.336
Fly
primary mirna processing GO:0031053 3 0.333
positive regulation of catabolic process GO:0009896 310 0.332
negative regulation of cellular protein metabolic process GO:0032269 353 0.325
positive regulation of developmental process GO:0051094 314 0.321
olfactory bulb interneuron differentiation GO:0021889 2 0.314
segmentation GO:0035282 4 0.312
Fly
regulation of system process GO:0044057 101 0.312
Fly
digestive system development GO:0055123 75 0.302
cell development GO:0048468 328 0.300
Fly
nucleobase containing compound transport GO:0015931 51 0.289
single organism cellular localization GO:1902580 332 0.285
response to nitrogen compound GO:1901698 184 0.281
Human Fly
regulation of cell development GO:0060284 161 0.273
regulation of glial cell proliferation GO:0060251 4 0.258
growth GO:0040007 202 0.257
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 15 0.242
Human
schwann cell development GO:0014044 1 0.238
innate immune response activating signal transduction GO:0002758 48 0.233
protein targeting to nucleus GO:0044744 104 0.229
neuron projection development GO:0031175 106 0.227
hindlimb morphogenesis GO:0035137 2 0.227
cytoplasmic transport GO:0016482 379 0.224
positive regulation of protein transport GO:0051222 135 0.219
negative regulation of translation GO:0017148 37 0.216
regulation of gene silencing by mirna GO:0060964 6 0.214
embryonic hindlimb morphogenesis GO:0035116 2 0.206
hematopoietic or lymphoid organ development GO:0048534 186 0.206
neural crest cell development GO:0014032 3 0.197
forebrain neuron differentiation GO:0021879 3 0.183
anatomical structure formation involved in morphogenesis GO:0048646 284 0.180
Fly
regulation of translational initiation GO:0006446 24 0.176
Human
stem cell division GO:0017145 2 0.173
activation of innate immune response GO:0002218 55 0.172
hair cycle GO:0042633 28 0.171
heart development GO:0007507 95 0.169
regeneration GO:0031099 4 0.169
peripheral nervous system development GO:0007422 2 0.168
meiotic chromosome segregation GO:0045132 4 0.164
rna interference GO:0016246 4 0.157
Fly
negative regulation of cell differentiation GO:0045596 171 0.154
Fly
ribonucleoprotein complex assembly GO:0022618 78 0.149
Fly
cellular component disassembly GO:0022411 92 0.148
behavior GO:0007610 112 0.144
Fly
regulation of mrna processing GO:0050684 48 0.142
regulation of cell cycle GO:0051726 393 0.135
cell projection organization GO:0030030 252 0.133
establishment of protein localization to organelle GO:0072594 172 0.133
regulation of schwann cell proliferation GO:0010624 1 0.129
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.128
positive regulation of cellular catabolic process GO:0031331 284 0.127
regulation of growth GO:0040008 165 0.120
neurological system process GO:0050877 163 0.120
Fly
embryo development GO:0009790 123 0.117
Fly
rna transport GO:0050658 39 0.115
stem cell differentiation GO:0048863 93 0.114
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.114
regulation of membrane potential GO:0042391 95 0.114
signal transduction by phosphorylation GO:0023014 297 0.114
reproductive system development GO:0061458 56 0.112
cell morphogenesis GO:0000902 296 0.109
aging GO:0007568 66 0.109
embryonic morphogenesis GO:0048598 85 0.109
mitotic cell cycle GO:0000278 326 0.107
epidermis development GO:0008544 59 0.107
tube morphogenesis GO:0035239 95 0.106
molting cycle GO:0042303 28 0.106
cellular macromolecular complex assembly GO:0034622 324 0.105
Fly
regulation of myelination GO:0031641 1 0.103
mirna metabolic process GO:0010586 10 0.101
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.101
negative regulation of gliogenesis GO:0014014 3 0.098
negative regulation of developmental process GO:0051093 247 0.098
Fly
regulation of cell migration GO:0030334 289 0.097
mrna 3 end processing GO:0031124 24 0.097
reproductive process GO:0022414 106 0.097
Fly
hair cycle process GO:0022405 12 0.097
positive regulation of transcription factor import into nucleus GO:0042993 25 0.096
developmental growth GO:0048589 48 0.096
oogenesis GO:0048477 2 0.096
Fly
ribonucleoprotein complex subunit organization GO:0071826 81 0.096
Fly
stem cell proliferation GO:0072089 25 0.094
Human
heart morphogenesis GO:0003007 48 0.092
protein localization to organelle GO:0033365 280 0.091
negative regulation of multicellular organismal process GO:0051241 317 0.091
regulation of innate immune response GO:0045088 97 0.090
nitrogen compound transport GO:0071705 191 0.090
regulation of posttranscriptional gene silencing GO:0060147 6 0.088
intracellular protein transport GO:0006886 270 0.087
cell type specific apoptotic process GO:0097285 125 0.086
epithelium development GO:0060429 227 0.085
spermatid development GO:0007286 4 0.085
neuron differentiation GO:0030182 138 0.085
positive regulation of organelle organization GO:0010638 195 0.081
positive regulation of transport GO:0051050 336 0.080
negative regulation of intracellular signal transduction GO:1902532 183 0.080
positive regulation of immune response GO:0050778 159 0.077
spermatid differentiation GO:0048515 4 0.076
positive regulation of interferon beta production GO:0032728 17 0.076
formation of primary germ layer GO:0001704 42 0.074
immune response activating signal transduction GO:0002757 90 0.074
generation of neurons GO:0048699 152 0.073
mesenchyme development GO:0060485 59 0.073
protein targeting GO:0006605 187 0.073
sex differentiation GO:0007548 45 0.072
regulation of cell differentiation GO:0045595 393 0.072
Fly
dna catabolic process GO:0006308 49 0.071
viral life cycle GO:0019058 132 0.071
nervous system development GO:0007399 293 0.071
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.069
interspecies interaction between organisms GO:0044419 156 0.069
positive regulation of cellular component organization GO:0051130 376 0.066
regulation of defense response GO:0031347 154 0.066
cellular component assembly involved in morphogenesis GO:0010927 73 0.065
regulation of organ morphogenesis GO:2000027 24 0.065
regulation of cytokine production GO:0001817 232 0.064
protein import GO:0017038 130 0.064
cellular component morphogenesis GO:0032989 314 0.063
dna catabolic process endonucleolytic GO:0000737 37 0.063
negative regulation of schwann cell proliferation GO:0010626 1 0.062
cardiac muscle tissue development GO:0048738 39 0.062
amine metabolic process GO:0009308 44 0.062
regulation of viral process GO:0050792 103 0.061
positive regulation of immune system process GO:0002684 283 0.061
cognition GO:0050890 43 0.061
Fly
digestive tract morphogenesis GO:0048546 56 0.060
intracellular receptor signaling pathway GO:0030522 104 0.058
mesenchymal cell development GO:0014031 50 0.058
mrna cleavage GO:0006379 5 0.058
Human Fly
oligodendrocyte differentiation GO:0048709 7 0.058
positive regulation of defense response to virus by host GO:0002230 14 0.057
nucleocytoplasmic transport GO:0006913 176 0.057
ventral spinal cord development GO:0021517 1 0.056
regulation of protein localization GO:0032880 296 0.055
viral process GO:0016032 146 0.055
organ morphogenesis GO:0009887 147 0.055
respiratory tube development GO:0030323 20 0.055
olfactory lobe development GO:0021988 5 0.055
cell part morphogenesis GO:0032990 137 0.055
response to biotic stimulus GO:0009607 276 0.054
activation of immune response GO:0002253 114 0.054
mitotic cell cycle phase transition GO:0044772 162 0.053
positive regulation of interferon alpha production GO:0032727 11 0.051
compound eye development GO:0048749 1 0.051
muscle cell differentiation GO:0042692 63 0.051
regulation of cell motility GO:2000145 299 0.050
memory GO:0007613 3 0.050
microtubule based process GO:0007017 210 0.049
negative regulation of immune effector process GO:0002698 38 0.048
morphogenesis of a branching structure GO:0001763 21 0.048
digestive tract development GO:0048565 75 0.048
cell projection morphogenesis GO:0048858 129 0.047
epithelial cell differentiation GO:0030855 141 0.046
protein sumoylation GO:0016925 25 0.046
regulation of mirna metabolic process GO:2000628 5 0.046
negative regulation of neurogenesis GO:0050768 26 0.046
regulation of locomotion GO:0040012 329 0.046
striated muscle tissue development GO:0014706 59 0.046
interferon beta production GO:0032608 23 0.045
response to virus GO:0009615 126 0.044
neuron projection morphogenesis GO:0048812 50 0.044
blood vessel morphogenesis GO:0048514 162 0.044
learning GO:0007612 11 0.044
Fly
stem cell maintenance GO:0019827 19 0.044
Fly
negative regulation of type i interferon production GO:0032480 5 0.043
positive regulation of cytoplasmic transport GO:1903651 82 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
multicellular organismal reproductive process GO:0048609 40 0.043
Fly
multicellular organismal signaling GO:0035637 34 0.043
wound healing GO:0042060 115 0.042
embryonic hemopoiesis GO:0035162 4 0.042
negative regulation of programmed cell death GO:0043069 321 0.042
head development GO:0060322 108 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
multi organism reproductive process GO:0044703 54 0.042
Fly
skeletal system development GO:0001501 79 0.042
single organism reproductive process GO:0044702 98 0.042
Fly
regulation of interferon beta production GO:0032648 22 0.042
hemopoiesis GO:0030097 180 0.041
establishment of rna localization GO:0051236 39 0.041
cytokine production GO:0001816 247 0.041
development of primary sexual characteristics GO:0045137 35 0.041
central nervous system development GO:0007417 123 0.040
response to wounding GO:0009611 168 0.040
regulation of cellular component movement GO:0051270 334 0.040
regulation of protein transport GO:0051223 213 0.040
regulation of intracellular transport GO:0032386 195 0.039
regulation of mrna stability GO:0043488 23 0.039
cardiac muscle cell development GO:0055013 5 0.038
transmission of nerve impulse GO:0019226 11 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
brain development GO:0007420 97 0.037
female gamete generation GO:0007292 2 0.037
Fly
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.037
regulation of cell cycle process GO:0010564 266 0.036
skeletal muscle tissue regeneration GO:0043403 2 0.036
regulation of neuron differentiation GO:0045664 70 0.036
reproductive structure development GO:0048608 55 0.036
limb development GO:0060173 23 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
negative regulation of apoptotic process GO:0043066 316 0.035
regulation of cytoplasmic transport GO:1903649 149 0.035
endoderm formation GO:0001706 33 0.034
negative regulation of cytokine production GO:0001818 82 0.034
tube development GO:0035295 125 0.034
protein localization to nucleus GO:0034504 136 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.033
defense response GO:0006952 315 0.033
cellular response to dna damage stimulus GO:0006974 379 0.033
nuclear transport GO:0051169 179 0.033
inorganic ion transmembrane transport GO:0098660 231 0.033
regulation of protein targeting GO:1903533 91 0.033
pattern specification process GO:0007389 43 0.033
Fly
response to other organism GO:0051707 261 0.033
myoblast differentiation GO:0045445 21 0.032
cellular response to nutrient levels GO:0031669 69 0.032
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.032
multicellular organism reproduction GO:0032504 42 0.032
Fly
tooth mineralization GO:0034505 6 0.032
locomotory behavior GO:0007626 1 0.032
cellular amino acid metabolic process GO:0006520 116 0.031
positive regulation of innate immune response GO:0045089 79 0.031
embryonic organ development GO:0048568 36 0.031
spindle assembly GO:0051225 29 0.031
connective tissue development GO:0061448 39 0.031
developmental process involved in reproduction GO:0003006 66 0.031
Fly
negative regulation of defense response to virus GO:0050687 10 0.031
protein modification by small protein conjugation GO:0032446 342 0.030
rna localization GO:0006403 41 0.030
negative regulation of cell cycle GO:0045786 193 0.030
angiogenesis GO:0001525 147 0.030
organelle assembly GO:0070925 176 0.030
regulation of intracellular protein transport GO:0033157 123 0.029
positive regulation of developmental growth GO:0048639 16 0.029
nucleic acid transport GO:0050657 39 0.029
reproduction GO:0000003 63 0.029
Fly
viral genome replication GO:0019079 50 0.028
positive regulation of cell development GO:0010720 92 0.028
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.028
innate immune response GO:0045087 178 0.028
peripheral nervous system axon ensheathment GO:0032292 1 0.028
purine nucleoside monophosphate catabolic process GO:0009128 158 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
mapk cascade GO:0000165 288 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of cell cycle phase transition GO:1901987 126 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
schwann cell differentiation GO:0014037 1 0.027
ribonucleoside monophosphate metabolic process GO:0009161 187 0.026
covalent chromatin modification GO:0016569 254 0.026
regulation of cellular response to stress GO:0080135 244 0.025
gliogenesis GO:0042063 21 0.025
neuron development GO:0048666 113 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
sensory organ development GO:0007423 52 0.025
cell cycle checkpoint GO:0000075 117 0.025
regulation of meiotic cell cycle GO:0051445 4 0.025
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.025
neurogenesis GO:0022008 169 0.025
spindle organization GO:0007051 53 0.025
primary neural tube formation GO:0014020 3 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
vesicle mediated transport GO:0016192 371 0.025
chromatin modification GO:0016568 298 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
regulation of multi organism process GO:0043900 157 0.024
nucleoside catabolic process GO:0009164 408 0.024
muscle cell development GO:0055001 29 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.024
motor neuron axon guidance GO:0008045 2 0.024
regulation of stem cell differentiation GO:2000736 56 0.024
inner ear morphogenesis GO:0042472 4 0.023
muscle organ development GO:0007517 56 0.023
negative regulation of gene expression epigenetic GO:0045814 19 0.023
Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.023
skin development GO:0043588 76 0.023
cardiocyte differentiation GO:0035051 23 0.023
multi organism cellular process GO:0044764 156 0.023
positive regulation of protein localization to nucleus GO:1900182 48 0.023
regulation of developmental growth GO:0048638 30 0.023
stem cell development GO:0048864 69 0.022
Fly
cation transport GO:0006812 331 0.022
gastrulation GO:0007369 51 0.022
cation transmembrane transport GO:0098655 238 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
multicellular organism growth GO:0035264 8 0.022
cellular response to starvation GO:0009267 58 0.022
dephosphorylation GO:0016311 209 0.022
positive regulation of mirna metabolic process GO:2000630 4 0.022
positive regulation of gene silencing by mirna GO:2000637 3 0.022
regulation of gene silencing GO:0060968 24 0.022
mda 5 signaling pathway GO:0039530 4 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
oocyte differentiation GO:0009994 2 0.021
Fly
positive regulation of neurogenesis GO:0050769 49 0.021
cellular ketone metabolic process GO:0042180 80 0.021
regulation of kinase activity GO:0043549 314 0.021
neurotransmitter secretion GO:0007269 4 0.021
positive regulation of intracellular transport GO:0032388 104 0.021
lipid metabolic process GO:0006629 381 0.021
monovalent inorganic cation transport GO:0015672 128 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
apoptotic signaling pathway GO:0097190 268 0.020
positive regulation of cytokine production GO:0001819 167 0.020
regulation of immune response GO:0050776 201 0.020
cellular lipid metabolic process GO:0044255 303 0.020
cell cycle phase transition GO:0044770 173 0.020
atp metabolic process GO:0046034 176 0.020
glial cell development GO:0021782 7 0.019
regulation of nucleocytoplasmic transport GO:0046822 98 0.019
gamete generation GO:0007276 25 0.019
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
negative regulation of catabolic process GO:0009895 104 0.019
regulation of transcription factor import into nucleus GO:0042990 39 0.019
hindbrain development GO:0030902 3 0.018
positive regulation of gliogenesis GO:0014015 4 0.018
gonad development GO:0008406 34 0.018
outer ear morphogenesis GO:0042473 2 0.018
chromatin silencing GO:0006342 12 0.018
Fly
cerebral cortex development GO:0021987 10 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
viral transcription GO:0019083 35 0.018
regulation of protein kinase activity GO:0045859 289 0.018
cell migration involved in gastrulation GO:0042074 1 0.018
cellular response to oxidative stress GO:0034599 85 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
negative regulation of mrna catabolic process GO:1902373 4 0.018
regulation of glial cell differentiation GO:0045685 3 0.018
positive regulation of transferase activity GO:0051347 227 0.018
dendrite development GO:0016358 24 0.018
nucleotide catabolic process GO:0009166 408 0.018
positive regulation of multi organism process GO:0043902 56 0.018
viral gene expression GO:0019080 35 0.017
immune response regulating signaling pathway GO:0002764 97 0.017
oocyte development GO:0048599 1 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
transmembrane transport GO:0055085 399 0.017
biomineral tissue development GO:0031214 39 0.017
immune response GO:0006955 307 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
immune system development GO:0002520 195 0.017
cerebellum development GO:0021549 2 0.017
chromatin organization GO:0006325 351 0.017
cardiac muscle cell differentiation GO:0055007 15 0.017
negative regulation of immune response GO:0050777 40 0.017
regulation of response to external stimulus GO:0032101 222 0.017
salivary gland morphogenesis GO:0007435 4 0.017
apoptotic nuclear changes GO:0030262 13 0.017
negative regulation of cell cycle phase transition GO:1901988 89 0.017
execution phase of apoptosis GO:0097194 32 0.017
rhythmic behavior GO:0007622 2 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
positive regulation of viral process GO:0048524 37 0.016
appendage development GO:0048736 23 0.016
single organism nuclear import GO:1902593 104 0.016
regulation of mda 5 signaling pathway GO:0039533 4 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
asymmetric stem cell division GO:0098722 1 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.016
defense response to virus GO:0051607 71 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
small molecule catabolic process GO:0044282 92 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
carbohydrate metabolic process GO:0005975 207 0.016
morphogenesis of an epithelium GO:0002009 60 0.016
adult locomotory behavior GO:0008344 1 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.016
neuronal action potential GO:0019228 9 0.016
organelle fission GO:0048285 149 0.016
cardiovascular system development GO:0072358 262 0.015
defense response to other organism GO:0098542 129 0.015
mitotic cell cycle process GO:1903047 286 0.015
sexual reproduction GO:0019953 37 0.015
Fly
regulation of transferase activity GO:0051338 355 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
mesenchymal cell differentiation GO:0048762 52 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
cell division GO:0051301 168 0.015
positive regulation of multicellular organism growth GO:0040018 6 0.015
synaptic vesicle exocytosis GO:0016079 3 0.015
organophosphate catabolic process GO:0046434 430 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
endosome to lysosome transport GO:0008333 21 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
cellular amine metabolic process GO:0044106 41 0.015
dna repair GO:0006281 198 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
myelination GO:0042552 6 0.015
neural tube formation GO:0001841 3 0.015
cell fate determination GO:0001709 3 0.015
Fly
regulation of type i interferon production GO:0032479 26 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
wnt signaling pathway GO:0016055 156 0.014
secretion by cell GO:0032940 226 0.014
negative regulation of nervous system development GO:0051961 28 0.014
ion transmembrane transport GO:0034220 338 0.014
cell cycle g1 s phase transition GO:0044843 80 0.014
central nervous system neuron differentiation GO:0021953 9 0.014
regulation of multicellular organism growth GO:0040014 8 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
neuromuscular junction development GO:0007528 3 0.014
striated muscle cell development GO:0055002 27 0.014
action potential GO:0001508 34 0.014
regulation of cardiac muscle cell proliferation GO:0060043 4 0.014

EIF2C1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.265
thyroid gland disease DOID:50 11 0.136
endocrine system disease DOID:28 26 0.136
cancer DOID:162 167 0.081
organ system cancer DOID:0050686 164 0.081
respiratory system cancer DOID:0050615 16 0.033
central nervous system disease DOID:331 186 0.025
nervous system disease DOID:863 431 0.025
musculoskeletal system disease DOID:17 223 0.015
muscular disease DOID:0080000 114 0.014