Homo sapiens

18 known processes

AP3B1

adaptor-related protein complex 3, beta 1 subunit

(Aliases: HPS,PE,HPS2,ADTB3,ADTB3A)

AP3B1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.189
Worm
anterograde axon cargo transport GO:0008089 1 0.172
Mouse
axon cargo transport GO:0008088 2 0.099
Mouse
maintenance of location GO:0051235 112 0.092
Worm
multicellular organismal aging GO:0010259 3 0.089
oogenesis GO:0048477 2 0.089
intracellular protein transport GO:0006886 270 0.088
Mouse
organophosphate catabolic process GO:0046434 430 0.081
female gamete generation GO:0007292 2 0.076
determination of adult lifespan GO:0008340 2 0.076
negative regulation of protein metabolic process GO:0051248 391 0.072
purine ribonucleoside metabolic process GO:0046128 437 0.070
purine nucleoside triphosphate metabolic process GO:0009144 412 0.069
nucleoside catabolic process GO:0009164 408 0.068
single organism cellular localization GO:1902580 332 0.067
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.066
nucleoside triphosphate metabolic process GO:0009141 422 0.061
ras protein signal transduction GO:0007265 73 0.060
vesicle mediated transport GO:0016192 371 0.060
Mouse
defense response GO:0006952 315 0.057
positive regulation of cellular component organization GO:0051130 376 0.055
microtubule based process GO:0007017 210 0.054
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.052
actin filament based process GO:0030029 224 0.052
purine nucleotide catabolic process GO:0006195 405 0.052
cellular response to dna damage stimulus GO:0006974 379 0.051
carbohydrate derivative biosynthetic process GO:1901137 207 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.049
oocyte development GO:0048599 1 0.049
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.048
lipid biosynthetic process GO:0008610 177 0.047
ribonucleoside triphosphate metabolic process GO:0009199 412 0.046
oocyte differentiation GO:0009994 2 0.046
cytoplasmic transport GO:0016482 379 0.046
Mouse
organelle localization GO:0051640 84 0.045
Mouse
ribonucleoside catabolic process GO:0042454 406 0.045
immune response GO:0006955 307 0.045
amine metabolic process GO:0009308 44 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
purine nucleoside catabolic process GO:0006152 398 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.042
protein processing GO:0016485 226 0.042
cellular amide metabolic process GO:0043603 69 0.041
organelle assembly GO:0070925 176 0.041
lipid localization GO:0010876 106 0.040
Worm
positive regulation of developmental process GO:0051094 314 0.039
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.039
cellular ketone metabolic process GO:0042180 80 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
small gtpase mediated signal transduction GO:0007264 78 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.037
cellular amine metabolic process GO:0044106 41 0.037
rho protein signal transduction GO:0007266 26 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
cell development GO:0048468 328 0.036
cellular macromolecular complex assembly GO:0034622 324 0.035
organophosphate biosynthetic process GO:0090407 163 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
embryo development GO:0009790 123 0.034
Worm
establishment of protein localization to organelle GO:0072594 172 0.034
Mouse
negative regulation of catalytic activity GO:0043086 335 0.034
regulation of cellular component biogenesis GO:0044087 281 0.033
regulation of protein complex assembly GO:0043254 147 0.033
protein localization to organelle GO:0033365 280 0.033
Mouse
carbohydrate metabolic process GO:0005975 207 0.033
ribonucleotide catabolic process GO:0009261 405 0.032
positive regulation of catabolic process GO:0009896 310 0.032
positive regulation of organelle organization GO:0010638 195 0.032
protein maturation GO:0051604 233 0.032
innate immune response GO:0045087 178 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
microtubule cytoskeleton organization GO:0000226 176 0.031
endocytosis GO:0006897 159 0.031
morphogenesis of embryonic epithelium GO:0016331 4 0.031
regulation of hormone levels GO:0010817 125 0.030
positive regulation of transport GO:0051050 336 0.030
positive regulation of hydrolase activity GO:0051345 331 0.030
nucleoside monophosphate metabolic process GO:0009123 191 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
actin cytoskeleton organization GO:0030036 207 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
regulation of transferase activity GO:0051338 355 0.029
system process GO:0003008 349 0.028
glycoprotein biosynthetic process GO:0009101 91 0.028
rna processing GO:0006396 255 0.028
cellular homeostasis GO:0019725 196 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.028
spermatid differentiation GO:0048515 4 0.028
regulation of proteolysis GO:0030162 293 0.028
single organism carbohydrate metabolic process GO:0044723 193 0.027
negative regulation of protein maturation GO:1903318 142 0.027
atp metabolic process GO:0046034 176 0.027
nuclear division GO:0000280 128 0.027
spermatid development GO:0007286 4 0.027
protein catabolic process GO:0030163 325 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
response to abiotic stimulus GO:0009628 336 0.026
macromolecule glycosylation GO:0043413 63 0.026
mitochondrion organization GO:0007005 156 0.026
secretion by cell GO:0032940 226 0.026
protein o linked glycosylation via serine GO:0018242 3 0.026
membrane organization GO:0061024 292 0.026
nucleotide catabolic process GO:0009166 408 0.026
biological adhesion GO:0022610 331 0.025
gtp metabolic process GO:0046039 239 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
purine ribonucleotide biosynthetic process GO:0009152 79 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
hormone catabolic process GO:0042447 4 0.025
negative regulation of cell differentiation GO:0045596 171 0.025
regulation of cell cycle GO:0051726 393 0.025
blastoderm segmentation GO:0007350 2 0.025
regulation of protein processing GO:0070613 150 0.025
negative regulation of protein processing GO:0010955 142 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
response to wounding GO:0009611 168 0.025
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
regulation of protein maturation GO:1903317 150 0.025
neuroblast proliferation GO:0007405 4 0.025
cell morphogenesis GO:0000902 296 0.024
neuromuscular junction development GO:0007528 3 0.024
oxidation reduction process GO:0055114 396 0.024
cell division GO:0051301 168 0.024
meiosis i GO:0007127 4 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
nucleoside monophosphate catabolic process GO:0009125 159 0.023
regulation of intracellular transport GO:0032386 195 0.023
chemical homeostasis GO:0048878 306 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.022
lipid metabolic process GO:0006629 381 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
gtp catabolic process GO:0006184 237 0.022
positive regulation of protein complex assembly GO:0031334 86 0.022
cell activation GO:0001775 213 0.022
Mouse
locomotory behavior GO:0007626 1 0.022
cellular protein complex assembly GO:0043623 188 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
nervous system development GO:0007399 293 0.021
purine containing compound biosynthetic process GO:0072522 88 0.021
cellular chemical homeostasis GO:0055082 180 0.021
regulation of ras protein signal transduction GO:0046578 155 0.021
protein glycosylation GO:0006486 62 0.021
regeneration GO:0031099 4 0.021
cellular lipid metabolic process GO:0044255 303 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
positive regulation of immune system process GO:0002684 283 0.020
Mouse
cation homeostasis GO:0055080 189 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
memory GO:0007613 3 0.020
response to other organism GO:0051707 261 0.020
reproductive process GO:0022414 106 0.020
establishment of organelle localization GO:0051656 59 0.020
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
peptide metabolic process GO:0006518 51 0.020
rab protein signal transduction GO:0032482 4 0.020
negative regulation of protein modification process GO:0031400 200 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
response to biotic stimulus GO:0009607 276 0.020
endomembrane system organization GO:0010256 196 0.019
regulation of protein localization GO:0032880 296 0.019
regulation of protein kinase activity GO:0045859 289 0.019
regulation of gtp catabolic process GO:0033124 180 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
protein targeting GO:0006605 187 0.019
Mouse
positive regulation of ras gtpase activity GO:0032320 117 0.019
mitotic cell cycle GO:0000278 326 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
regulation of kinase activity GO:0043549 314 0.019
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of multi organism process GO:0043900 157 0.018
regulation of protein catabolic process GO:0042176 155 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
response to oxygen containing compound GO:1901700 369 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
glycosylation GO:0070085 71 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
secretion GO:0046903 254 0.018
cellular cation homeostasis GO:0030003 163 0.018
immune effector process GO:0002252 159 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
cellular component morphogenesis GO:0032989 314 0.018
organelle inheritance GO:0048308 2 0.017
positive regulation of cell death GO:0010942 263 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
cell adhesion GO:0007155 325 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.017
tripartite regional subdivision GO:0007351 2 0.017
mitotic cell cycle process GO:1903047 286 0.017
single organism reproductive process GO:0044702 98 0.017
cation transport GO:0006812 331 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
regulation of cell differentiation GO:0045595 393 0.017
Mouse
segmentation GO:0035282 4 0.017
organelle fission GO:0048285 149 0.017
regulation of cytokine production GO:0001817 232 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
ion homeostasis GO:0050801 230 0.017
negative regulation of proteolysis GO:0045861 132 0.016
monocyte activation GO:0042117 3 0.016
regulation of dna metabolic process GO:0051052 153 0.016
microtubule based movement GO:0007018 32 0.016
Mouse
mrna processing GO:0006397 133 0.016
regulation of response to external stimulus GO:0032101 222 0.016
cell part morphogenesis GO:0032990 137 0.016
neurogenesis GO:0022008 169 0.016
nitrogen compound transport GO:0071705 191 0.016
protein oligomerization GO:0051259 173 0.016
regulation of protein transport GO:0051223 213 0.016
response to external biotic stimulus GO:0043207 261 0.016
neurological system process GO:0050877 163 0.016
establishment of vesicle localization GO:0051650 23 0.016
Mouse
dephosphorylation GO:0016311 209 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
adult locomotory behavior GO:0008344 1 0.016
tissue regeneration GO:0042246 3 0.016
regulation of ion transport GO:0043269 189 0.016
mitochondrion distribution GO:0048311 3 0.016
dna repair GO:0006281 198 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of cell adhesion GO:0030155 166 0.016
regulation of cell motility GO:2000145 299 0.016
regulation of gtpase activity GO:0043087 180 0.016
cell cycle phase transition GO:0044770 173 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
regulation of peptidase activity GO:0052547 180 0.016
mrna metabolic process GO:0016071 175 0.016
protein polymerization GO:0051258 71 0.016
alcohol metabolic process GO:0006066 114 0.016
lipid storage GO:0019915 28 0.016
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
g protein coupled receptor signaling pathway GO:0007186 207 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
response to axon injury GO:0048678 1 0.015
cell projection morphogenesis GO:0048858 129 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
regulation of cell cycle process GO:0010564 266 0.015
regulation of actin filament based process GO:0032970 141 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
transmembrane transport GO:0055085 399 0.015
purine nucleotide biosynthetic process GO:0006164 84 0.015
endosomal transport GO:0016197 129 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
sensory perception of pain GO:0019233 4 0.015
regulation of defense response GO:0031347 154 0.015
response to cytokine GO:0034097 232 0.015
chromatin modification GO:0016568 298 0.015
protein targeting to nucleus GO:0044744 104 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
negative regulation of developmental process GO:0051093 247 0.014
response to radiation GO:0009314 151 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
defense response to other organism GO:0098542 129 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
chromatin organization GO:0006325 351 0.014
regulation of immune response GO:0050776 201 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
anterior posterior axis specification GO:0009948 2 0.014
response to growth factor GO:0070848 205 0.014
glycoprotein metabolic process GO:0009100 110 0.014
regulation of cell development GO:0060284 161 0.014
covalent chromatin modification GO:0016569 254 0.014
cytokine production GO:0001816 247 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
generation of neurons GO:0048699 152 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
cytokinesis GO:0000910 96 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
vesicle localization GO:0051648 26 0.014
Mouse
ribose phosphate biosynthetic process GO:0046390 82 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
regulation of protein targeting GO:1903533 91 0.014
positive regulation of cell cycle GO:0045787 140 0.014
single organism membrane organization GO:0044802 268 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
compound eye development GO:0048749 1 0.014
metal ion homeostasis GO:0055065 169 0.014
translation GO:0006412 132 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
wound healing GO:0042060 115 0.013
Mouse
regulation of cell migration GO:0030334 289 0.013
purine containing compound catabolic process GO:0072523 411 0.013
actin filament organization GO:0007015 128 0.013
cation transmembrane transport GO:0098655 238 0.013
t cell activation GO:0042110 99 0.013
Mouse
negative regulation of organelle organization GO:0010639 126 0.013
reproduction GO:0000003 63 0.013
hormone metabolic process GO:0042445 61 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
cell projection organization GO:0030030 252 0.013
neural tube formation GO:0001841 3 0.013
synaptic transmission GO:0007268 61 0.013
Mouse
regulation of membrane potential GO:0042391 95 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
negative regulation of transport GO:0051051 176 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
histone modification GO:0016570 251 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of metal ion transport GO:0010959 120 0.013
actin filament based movement GO:0030048 17 0.013
golgi vesicle transport GO:0048193 80 0.013
negative regulation of apoptotic process GO:0043066 316 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
action potential GO:0001508 34 0.012
leukocyte activation GO:0045321 164 0.012
Mouse
cellular component disassembly GO:0022411 92 0.012
negative regulation of transferase activity GO:0051348 124 0.012
immune system development GO:0002520 195 0.012
Mouse
regulation of behavior GO:0050795 82 0.012
rhythmic behavior GO:0007622 2 0.012
macromolecular complex disassembly GO:0032984 60 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
divalent inorganic cation transport GO:0072511 158 0.012
cell growth GO:0016049 160 0.012
regulation of growth GO:0040008 165 0.012
calcium ion homeostasis GO:0055074 122 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
growth GO:0040007 202 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
cellular ion homeostasis GO:0006873 168 0.012
regulation of protein localization to nucleus GO:1900180 85 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
regulation of cellular component movement GO:0051270 334 0.012
vacuole organization GO:0007033 44 0.012
Worm
peripheral nervous system development GO:0007422 2 0.012
protein import GO:0017038 130 0.012
receptor mediated endocytosis GO:0006898 84 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
sequestering of metal ion GO:0051238 24 0.012
positive regulation of transferase activity GO:0051347 227 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
synaptic vesicle endocytosis GO:0048488 2 0.012
regulation of cytoplasmic transport GO:1903649 149 0.011
detection of stimulus GO:0051606 85 0.011
intracellular mrna localization GO:0008298 1 0.011
taxis GO:0042330 157 0.011
double strand break repair GO:0006302 101 0.011
neurotransmitter secretion GO:0007269 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
lytic vacuole organization GO:0080171 24 0.011
Worm
single organismal cell cell adhesion GO:0016337 148 0.011
actin mediated cell contraction GO:0070252 12 0.011
positive regulation of immune response GO:0050778 159 0.011
spindle elongation GO:0051231 4 0.011
viral process GO:0016032 146 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
ion transmembrane transport GO:0034220 338 0.011
spindle organization GO:0007051 53 0.011
mitotic nuclear division GO:0007067 119 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
long term memory GO:0007616 2 0.011
neuron differentiation GO:0030182 138 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
regulation of cellular response to stress GO:0080135 244 0.011
cell chemotaxis GO:0060326 112 0.011
plasma membrane organization GO:0007009 115 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
Mouse
negative regulation of cell proliferation GO:0008285 228 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
atp catabolic process GO:0006200 157 0.011
negative regulation of cell death GO:0060548 345 0.011
apoptotic signaling pathway GO:0097190 268 0.011
associative learning GO:0008306 1 0.011
regulation of rab gtpase activity GO:0032313 39 0.011
cilium organization GO:0044782 68 0.010
positive regulation of dendrite morphogenesis GO:0050775 3 0.010
negative regulation of kinase activity GO:0033673 106 0.010
single organism cell adhesion GO:0098602 179 0.010
response to organic cyclic compound GO:0014070 204 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
regulation of translation GO:0006417 89 0.010
cellular protein catabolic process GO:0044257 261 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
protein acylation GO:0043543 138 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
regulation of rho protein signal transduction GO:0035023 79 0.010
regulation of actin filament length GO:0030832 56 0.010
regulation of cell division GO:0051302 116 0.010
rna splicing GO:0008380 131 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
regulation of vasculature development GO:1901342 97 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
central nervous system development GO:0007417 123 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
motor neuron axon guidance GO:0008045 2 0.010

AP3B1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.066
central nervous system disease DOID:331 186 0.040
nervous system disease DOID:863 431 0.040
amino acid metabolic disorder DOID:9252 50 0.032
inherited metabolic disorder DOID:655 242 0.032
disease of cellular proliferation DOID:14566 174 0.026
cancer DOID:162 167 0.021
organ system cancer DOID:0050686 164 0.021
neurodegenerative disease DOID:1289 102 0.021
sensory system disease DOID:0050155 203 0.018
brain disease DOID:936 73 0.016
immune system disease DOID:2914 155 0.016
hematopoietic system disease DOID:74 100 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
disease of mental health DOID:150 70 0.012
epilepsy syndrome DOID:1826 41 0.011
musculoskeletal system disease DOID:17 223 0.010