Homo sapiens

22 known processes

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

(Aliases: MGC15877,PPP1A,MGC1674,PP-1A,PP1alpha)

PPP1CA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dephosphorylation GO:0016311 209 0.999
negative regulation of phosphatase activity GO:0010923 61 0.998
negative regulation of catalytic activity GO:0043086 335 0.997
negative regulation of phosphorus metabolic process GO:0010563 267 0.992
copulation GO:0007620 1 0.987
regulation of cell cycle GO:0051726 393 0.975
positive regulation of phosphorylation GO:0042327 394 0.969
regulation of mapk cascade GO:0043408 262 0.961
negative regulation of cellular component organization GO:0051129 235 0.961
cellular response to dna damage stimulus GO:0006974 379 0.957
regulation of dephosphorylation GO:0035303 96 0.953
protein processing GO:0016485 226 0.952
positive regulation of transferase activity GO:0051347 227 0.952
negative regulation of phosphate metabolic process GO:0045936 267 0.943
regulation of proteolysis GO:0030162 293 0.942
regulation of cell cycle process GO:0010564 266 0.938
mitotic cell cycle process GO:1903047 286 0.920
negative regulation of cellular protein metabolic process GO:0032269 353 0.919
cell division GO:0051301 168 0.914
covalent chromatin modification GO:0016569 254 0.914
cellular homeostasis GO:0019725 196 0.904
erk1 and erk2 cascade GO:0070371 104 0.903
cellular macromolecule catabolic process GO:0044265 380 0.887
positive regulation of cellular component organization GO:0051130 376 0.880
cellular macromolecular complex assembly GO:0034622 324 0.879
protein dephosphorylation GO:0006470 81 0.878
dna damage checkpoint GO:0000077 68 0.875
mitotic cell cycle phase transition GO:0044772 162 0.873
insemination GO:0007320 1 0.864
neuron differentiation GO:0030182 138 0.863
limbic system development GO:0021761 3 0.856
energy derivation by oxidation of organic compounds GO:0015980 43 0.850
Rat
carbohydrate metabolic process GO:0005975 207 0.839
Rat
cell morphogenesis GO:0000902 296 0.824
cellular chemical homeostasis GO:0055082 180 0.816
negative regulation of apoptotic process GO:0043066 316 0.800
cell cycle checkpoint GO:0000075 117 0.800
negative regulation of cell death GO:0060548 345 0.797
negative regulation of cell cycle GO:0045786 193 0.793
cell projection organization GO:0030030 252 0.790
organelle fission GO:0048285 149 0.760
intrinsic apoptotic signaling pathway GO:0097193 127 0.753
generation of precursor metabolites and energy GO:0006091 68 0.747
Rat
ubiquitin dependent protein catabolic process GO:0006511 206 0.746
oogenesis GO:0048477 2 0.736
negative regulation of cell cycle phase transition GO:1901988 89 0.734
adult locomotory behavior GO:0008344 1 0.734
chromosome segregation GO:0007059 114 0.733
chemical homeostasis GO:0048878 306 0.729
regulation of cell cycle phase transition GO:1901987 126 0.723
regulation of synaptic plasticity GO:0048167 3 0.722
regulation of cellular amine metabolic process GO:0033238 11 0.713
negative regulation of multicellular organismal process GO:0051241 317 0.713
positive regulation of cell death GO:0010942 263 0.711
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 118 0.707
protein maturation GO:0051604 233 0.705
organelle assembly GO:0070925 176 0.705
mapk cascade GO:0000165 288 0.700
system process GO:0003008 349 0.693
cellular component morphogenesis GO:0032989 314 0.685
cell development GO:0048468 328 0.685
regulation of protein maturation GO:1903317 150 0.681
oxidation reduction process GO:0055114 396 0.678
Rat
ras protein signal transduction GO:0007265 73 0.676
single organism membrane organization GO:0044802 268 0.670
modification dependent protein catabolic process GO:0019941 209 0.655
negative regulation of hydrolase activity GO:0051346 182 0.648
negative regulation of protein metabolic process GO:0051248 391 0.637
regulation of erk1 and erk2 cascade GO:0070372 99 0.636
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.624
cellular protein catabolic process GO:0044257 261 0.622
chromatin modification GO:0016568 298 0.620
cell adhesion GO:0007155 325 0.608
Human
protein modification by small protein conjugation GO:0032446 342 0.604
vesicle mediated transport GO:0016192 371 0.600
cell cycle phase transition GO:0044770 173 0.599
dna integrity checkpoint GO:0031570 71 0.596
nucleoside triphosphate metabolic process GO:0009141 422 0.585
regulation of growth GO:0040008 165 0.580
regulation of transferase activity GO:0051338 355 0.579
small gtpase mediated signal transduction GO:0007264 78 0.578
multicellular organismal aging GO:0010259 3 0.568
regulation of cell motility GO:2000145 299 0.567
regulation of cellular protein catabolic process GO:1903362 96 0.564
mitotic cell cycle GO:0000278 326 0.555
single organism carbohydrate metabolic process GO:0044723 193 0.555
Rat
negative regulation of programmed cell death GO:0043069 321 0.555
negative regulation of protein processing GO:0010955 142 0.551
regulation of mitotic cell cycle GO:0007346 189 0.548
regulation of peptidase activity GO:0052547 180 0.544
regulation of intracellular transport GO:0032386 195 0.540
cytosolic calcium ion homeostasis GO:0051480 89 0.532
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.529
post embryonic development GO:0009791 2 0.526
negative regulation of proteolysis GO:0045861 132 0.520
cell type specific apoptotic process GO:0097285 125 0.518
positive regulation of apoptotic signaling pathway GO:2001235 70 0.515
Mouse
peptidyl threonine phosphorylation GO:0018107 41 0.515
tube morphogenesis GO:0035239 95 0.508
Mouse
regulation of proteasomal protein catabolic process GO:0061136 87 0.506
regulation of establishment of protein localization GO:0070201 242 0.500
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.499
cellular protein complex assembly GO:0043623 188 0.486
regulation of chromosome segregation GO:0051983 44 0.484
organ morphogenesis GO:0009887 147 0.483
positive regulation of programmed cell death GO:0043068 249 0.481
Mouse
signal transduction by phosphorylation GO:0023014 297 0.479
neuron projection development GO:0031175 106 0.477
metal ion transport GO:0030001 272 0.475
regulation of transporter activity GO:0032409 82 0.474
response to radiation GO:0009314 151 0.464
Mouse
protein catabolic process GO:0030163 325 0.460
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.460
glycogen metabolic process GO:0005977 22 0.457
Rat
regulation of metal ion transport GO:0010959 120 0.456
regulation of protein catabolic process GO:0042176 155 0.445
neuron development GO:0048666 113 0.443
apoptotic signaling pathway GO:0097190 268 0.441
Mouse
visual learning GO:0008542 1 0.441
negative regulation of protein modification process GO:0031400 200 0.431
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.430
regulation of cell growth GO:0001558 135 0.424
embryo development GO:0009790 123 0.423
meiotic nuclear division GO:0007126 10 0.422
cellular metal ion homeostasis GO:0006875 146 0.417
positive regulation of cell proliferation GO:0008284 301 0.414
growth GO:0040007 202 0.412
taxis GO:0042330 157 0.412
negative regulation of mitotic cell cycle GO:0045930 102 0.410
actin filament based process GO:0030029 224 0.404
locomotory behavior GO:0007626 1 0.388
regulation of cell division GO:0051302 116 0.387
cell projection morphogenesis GO:0048858 129 0.386
response to organonitrogen compound GO:0010243 156 0.385
negative regulation of organelle organization GO:0010639 126 0.382
cellular ion homeostasis GO:0006873 168 0.380
regulation of cellular response to stress GO:0080135 244 0.361
regulation of cell morphogenesis GO:0022604 153 0.355
regulation of cellular component biogenesis GO:0044087 281 0.352
cation homeostasis GO:0055080 189 0.351
nervous system development GO:0007399 293 0.350
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.345
Mouse
regulation of endopeptidase activity GO:0052548 170 0.345
regulation of phosphatase activity GO:0010921 81 0.342
chromatin organization GO:0006325 351 0.338
cellular carbohydrate metabolic process GO:0044262 84 0.330
Rat
cell part morphogenesis GO:0032990 137 0.329
ribonucleoside catabolic process GO:0042454 406 0.322
purine nucleoside triphosphate catabolic process GO:0009146 392 0.320
regulation of mitotic sister chromatid separation GO:0010965 27 0.318
regulation of protein processing GO:0070613 150 0.315
female gamete generation GO:0007292 2 0.313
protein polymerization GO:0051258 71 0.306
energy reserve metabolic process GO:0006112 22 0.291
Rat
protein ubiquitination GO:0016567 314 0.289
regulation of cell projection organization GO:0031344 107 0.281
tube development GO:0035295 125 0.281
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.279
negative regulation of cell growth GO:0030308 83 0.279
chromosome separation GO:0051304 23 0.273
calcium ion transport GO:0006816 147 0.270
generation of neurons GO:0048699 152 0.268
associative learning GO:0008306 1 0.266
neuron projection morphogenesis GO:0048812 50 0.264
positive regulation of response to dna damage stimulus GO:2001022 43 0.260
regulation of cellular component movement GO:0051270 334 0.255
positive regulation of protein complex assembly GO:0031334 86 0.255
regulation of locomotion GO:0040012 329 0.254
neurological system process GO:0050877 163 0.251
cellular cation homeostasis GO:0030003 163 0.250
single organism cellular localization GO:1902580 332 0.250
cellular glucan metabolic process GO:0006073 22 0.249
Rat
positive regulation of protein phosphorylation GO:0001934 313 0.248
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.241
nuclear division GO:0000280 128 0.238
organelle localization GO:0051640 84 0.237
negative regulation of cell cycle process GO:0010948 121 0.233
modification dependent macromolecule catabolic process GO:0043632 212 0.227
response to nitrogen compound GO:1901698 184 0.226
positive regulation of cellular amine metabolic process GO:0033240 7 0.226
positive regulation of transport GO:0051050 336 0.224
endocytosis GO:0006897 159 0.223
metal ion homeostasis GO:0055065 169 0.219
negative regulation of growth GO:0045926 97 0.218
negative regulation of phosphorylation GO:0042326 174 0.217
cellular divalent inorganic cation homeostasis GO:0072503 128 0.217
defense response GO:0006952 315 0.214
divalent inorganic cation transport GO:0072511 158 0.212
regulation of intracellular protein transport GO:0033157 123 0.212
regulation of cell differentiation GO:0045595 393 0.211
peptidyl threonine modification GO:0018210 45 0.211
cell growth GO:0016049 160 0.210
cytokinesis GO:0000910 96 0.207
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.204
regulation of vesicle mediated transport GO:0060627 130 0.197
positive regulation of mapk cascade GO:0043410 190 0.194
regulation of cellular component size GO:0032535 82 0.192
positive regulation of cellular component biogenesis GO:0044089 158 0.191
neurogenesis GO:0022008 169 0.190
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.185
positive regulation of apoptotic process GO:0043065 246 0.182
Mouse
regulation of gene expression epigenetic GO:0040029 73 0.181
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.181
ion homeostasis GO:0050801 230 0.178
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.176
mitotic cell cycle checkpoint GO:0007093 68 0.176
biological adhesion GO:0022610 331 0.174
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.173
response to cytokine GO:0034097 232 0.173
cytoplasmic transport GO:0016482 379 0.169
negative regulation of protein maturation GO:1903318 142 0.167
regulation of calcium ion transport GO:0051924 79 0.167
cellular lipid metabolic process GO:0044255 303 0.166
histone modification GO:0016570 251 0.166
negative regulation of transport GO:0051051 176 0.164
regulation of mitochondrion organization GO:0010821 54 0.164
behavior GO:0007610 112 0.164
mitotic nuclear division GO:0007067 119 0.164
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.163
positive regulation of protein transport GO:0051222 135 0.162
proteasomal protein catabolic process GO:0010498 176 0.158
regulation of protein transport GO:0051223 213 0.158
regulation of protein complex assembly GO:0043254 147 0.155
membrane organization GO:0061024 292 0.153
signal transduction in response to dna damage GO:0042770 57 0.152
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.149
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.149
cellular ketone metabolic process GO:0042180 80 0.149
regulation of epithelial cell proliferation GO:0050678 113 0.148
reproductive process GO:0022414 106 0.147
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.146
apoptotic mitochondrial changes GO:0008637 57 0.143
cellular response to organonitrogen compound GO:0071417 124 0.143
regulation of dna metabolic process GO:0051052 153 0.141
actin filament organization GO:0007015 128 0.140
calcium ion homeostasis GO:0055074 122 0.139
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.138
atp metabolic process GO:0046034 176 0.137
purine nucleoside monophosphate catabolic process GO:0009128 158 0.133
meiotic cell cycle GO:0051321 13 0.132
regulation of cellular amino acid metabolic process GO:0006521 6 0.132
positive regulation of developmental process GO:0051094 314 0.131
cell morphogenesis involved in differentiation GO:0000904 144 0.131
regulation of neurogenesis GO:0050767 82 0.131
negative regulation of intracellular signal transduction GO:1902532 183 0.130
positive regulation of endopeptidase activity GO:0010950 84 0.129
regulation of response to dna damage stimulus GO:2001020 94 0.129
regulation of nervous system development GO:0051960 88 0.128
response to metal ion GO:0010038 84 0.128
positive regulation of catabolic process GO:0009896 310 0.124
regulation of protein ubiquitination GO:0031396 95 0.124
cation transport GO:0006812 331 0.121
regulation of kinase activity GO:0043549 314 0.120
oocyte differentiation GO:0009994 2 0.120
determination of adult lifespan GO:0008340 2 0.119
regulation of cytoplasmic transport GO:1903649 149 0.118
regulation of ion transmembrane transport GO:0034765 132 0.117
receptor mediated endocytosis GO:0006898 84 0.117
regulation of transmembrane transporter activity GO:0022898 74 0.117
negative regulation of apoptotic signaling pathway GO:2001234 97 0.116
g2 dna damage checkpoint GO:0031572 26 0.116
negative regulation of calcium ion transport GO:0051926 19 0.115
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.114
axonogenesis GO:0007409 31 0.114
telencephalon development GO:0021537 17 0.113
regulation of nuclear division GO:0051783 65 0.112
regulation of anatomical structure morphogenesis GO:0022603 286 0.112
regulation of blood circulation GO:1903522 59 0.111
negative regulation of cellular catabolic process GO:0031330 83 0.110
regulation of purine nucleotide metabolic process GO:1900542 264 0.110
mitotic sister chromatid segregation GO:0000070 53 0.109
regulation of transmembrane transport GO:0034762 139 0.106
adult behavior GO:0030534 18 0.105
dna replication GO:0006260 116 0.105
cellular response to cytokine stimulus GO:0071345 181 0.103
central nervous system development GO:0007417 123 0.102
positive regulation of protein catabolic process GO:0045732 75 0.102
carbohydrate catabolic process GO:0016052 36 0.100
Rat
brain development GO:0007420 97 0.100
meiotic chromosome segregation GO:0045132 4 0.100
oocyte development GO:0048599 1 0.099
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.099
dendrite morphogenesis GO:0048813 14 0.099
neuromuscular junction development GO:0007528 3 0.098
muscle system process GO:0003012 81 0.097
positive regulation of organelle organization GO:0010638 195 0.097
epithelium development GO:0060429 227 0.096
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.096
single organism reproductive process GO:0044702 98 0.095
regulation of dendrite development GO:0050773 18 0.095
negative regulation of sister chromatid segregation GO:0033046 17 0.095
positive regulation of kinase activity GO:0033674 204 0.094
regulation of map kinase activity GO:0043405 108 0.093
regulation of meiosis GO:0040020 3 0.093
intracellular protein transport GO:0006886 270 0.092
protein kinase b signaling GO:0043491 69 0.091
sensory organ development GO:0007423 52 0.090
reproduction GO:0000003 63 0.090
developmental process involved in reproduction GO:0003006 66 0.090
pigmentation GO:0043473 22 0.090
monovalent inorganic cation transport GO:0015672 128 0.088
dna templated transcription termination GO:0006353 3 0.087
regulation of apoptotic signaling pathway GO:2001233 175 0.086
Mouse
regulation of nucleocytoplasmic transport GO:0046822 98 0.085
cellular amine metabolic process GO:0044106 41 0.085
establishment of organelle localization GO:0051656 59 0.085
negative regulation of dephosphorylation GO:0035305 63 0.084
regulation of ubiquitin protein transferase activity GO:0051438 28 0.083
cellular response to nitrogen compound GO:1901699 144 0.082
regulation of meiotic cell cycle GO:0051445 4 0.082
dna repair GO:0006281 198 0.081
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.080
cardiovascular system development GO:0072358 262 0.079
Zebrafish
regulation of actin filament based process GO:0032970 141 0.078
actin polymerization or depolymerization GO:0008154 56 0.078
response to abiotic stimulus GO:0009628 336 0.078
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 156 0.077
regulation of ion transport GO:0043269 189 0.076
positive regulation of secretion GO:0051047 116 0.076
regulation of protein kinase activity GO:0045859 289 0.075
negative regulation of cellular protein catabolic process GO:1903363 38 0.075
signal transduction by p53 class mediator GO:0072331 72 0.073
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.072
reproductive structure development GO:0048608 55 0.071
amine metabolic process GO:0009308 44 0.070
secretion by cell GO:0032940 226 0.069
chemotaxis GO:0006935 157 0.068
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.068
regulation of protein localization GO:0032880 296 0.067
regulation of cell development GO:0060284 161 0.066
dendrite development GO:0016358 24 0.065
protein targeting GO:0006605 187 0.064
cellular response to abiotic stimulus GO:0071214 117 0.064
positive regulation of cell development GO:0010720 92 0.063
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.062
negative regulation of ion transport GO:0043271 39 0.062
divalent inorganic cation homeostasis GO:0072507 136 0.062
regulation of chromosome organization GO:0033044 103 0.062
regulation of secretion by cell GO:1903530 177 0.060
viral process GO:0016032 146 0.059
mitotic sister chromatid separation GO:0051306 18 0.059
positive regulation of proteolysis GO:0045862 142 0.059
regulation of protein dephosphorylation GO:0035304 18 0.059
establishment of protein localization to plasma membrane GO:0090002 68 0.059
sequestering of metal ion GO:0051238 24 0.058
positive regulation of dna repair GO:0045739 25 0.058
multicellular organism reproduction GO:0032504 42 0.058
regulation of centriole replication GO:0046599 7 0.057
positive regulation of hydrolase activity GO:0051345 331 0.057
ribonucleoside triphosphate metabolic process GO:0009199 412 0.056
renal system development GO:0072001 63 0.056
anatomical structure formation involved in morphogenesis GO:0048646 284 0.056
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 158 0.055
regulation of cell migration GO:0030334 289 0.055
maintenance of location GO:0051235 112 0.054
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.054
cellular response to growth factor stimulus GO:0071363 197 0.054
eye development GO:0001654 42 0.053
t cell homeostasis GO:0043029 3 0.053
actin filament polymerization GO:0030041 45 0.052
purine nucleoside catabolic process GO:0006152 398 0.052
regulation of membrane potential GO:0042391 95 0.051
negative regulation of cell division GO:0051782 31 0.051
developmental growth GO:0048589 48 0.050
plasma membrane organization GO:0007009 115 0.050
gland development GO:0048732 48 0.050
purine nucleoside monophosphate metabolic process GO:0009126 186 0.049
negative regulation of transferase activity GO:0051348 124 0.049
cellular response to oxygen containing compound GO:1901701 276 0.049
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.048
mitotic dna integrity checkpoint GO:0044774 30 0.048
positive regulation of peptidase activity GO:0010952 88 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
embryo development ending in birth or egg hatching GO:0009792 34 0.047
lipid metabolic process GO:0006629 381 0.047
monosaccharide metabolic process GO:0005996 74 0.047
Rat
epithelial cell proliferation GO:0050673 128 0.047
blood vessel morphogenesis GO:0048514 162 0.047
Zebrafish
central nervous system neuron development GO:0021954 7 0.046
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.046
response to light stimulus GO:0009416 87 0.046
Mouse
head development GO:0060322 108 0.046
protein localization to organelle GO:0033365 280 0.046
negative regulation of mapk cascade GO:0043409 56 0.045
cognition GO:0050890 43 0.045
regulation of protein kinase b signaling GO:0051896 61 0.044
response to oxygen containing compound GO:1901700 369 0.044
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.044
molting cycle GO:0042303 28 0.044
immune system development GO:0002520 195 0.043
golgi vesicle transport GO:0048193 80 0.043
development of primary sexual characteristics GO:0045137 35 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.042
purine ribonucleoside catabolic process GO:0046130 398 0.042
posttranscriptional regulation of gene expression GO:0010608 213 0.042
rna interference GO:0016246 4 0.041
positive regulation of growth GO:0045927 58 0.040
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.039
release of cytochrome c from mitochondria GO:0001836 35 0.039
histone phosphorylation GO:0016572 16 0.039
negative regulation of kinase activity GO:0033673 106 0.039
central nervous system neuron axonogenesis GO:0021955 3 0.038
leukocyte apoptotic process GO:0071887 31 0.038
divalent metal ion transport GO:0070838 152 0.038
ribonucleoprotein complex subunit organization GO:0071826 81 0.037
positive regulation of secretion by cell GO:1903532 108 0.037
sister chromatid segregation GO:0000819 54 0.036
reproductive system development GO:0061458 56 0.035
protein import GO:0017038 130 0.035
regulation of dna repair GO:0006282 47 0.035
negative regulation of response to dna damage stimulus GO:2001021 33 0.035
developmental programmed cell death GO:0010623 3 0.035
peptidyl serine phosphorylation GO:0018105 101 0.035
response to inorganic substance GO:0010035 127 0.035
single organism membrane fusion GO:0044801 37 0.035
protein acylation GO:0043543 138 0.035
negative regulation of endopeptidase activity GO:0010951 84 0.034
negative regulation of protein kinase activity GO:0006469 98 0.034
innate immune response GO:0045087 178 0.033
fatty acid metabolic process GO:0006631 115 0.033
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.033
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.033
regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 8 0.033
rna processing GO:0006396 255 0.032
multi organism cellular process GO:0044764 156 0.032
purine containing compound catabolic process GO:0072523 411 0.032
regulation of sister chromatid segregation GO:0033045 27 0.032
regulation of mitosis GO:0007088 63 0.031
negative regulation of chromosome organization GO:2001251 48 0.031
glucose metabolic process GO:0006006 45 0.031
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.031
regulation of heart rate GO:0002027 38 0.031
glycosyl compound catabolic process GO:1901658 413 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.030
regulation of dendrite morphogenesis GO:0048814 11 0.030
ribonucleoside monophosphate metabolic process GO:0009161 187 0.030
peptidyl tyrosine phosphorylation GO:0018108 170 0.030
rhythmic process GO:0048511 31 0.030
cell aging GO:0007569 52 0.030
glycoprotein metabolic process GO:0009100 110 0.029
response to endoplasmic reticulum stress GO:0034976 49 0.029
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.029
regulation of anatomical structure size GO:0090066 101 0.029
positive regulation of developmental growth GO:0048639 16 0.029
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.028
cellular polysaccharide metabolic process GO:0044264 27 0.028
Rat
regulation of glycogen metabolic process GO:0070873 15 0.028
Rat
metaphase anaphase transition of cell cycle GO:0044784 21 0.028
cellular calcium ion homeostasis GO:0006874 117 0.027
cell cell signaling GO:0007267 155 0.027
mesenchyme development GO:0060485 59 0.027
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.027
urogenital system development GO:0001655 65 0.027
cardiac muscle cell contraction GO:0086003 4 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.026
phospholipid metabolic process GO:0006644 99 0.026
transmembrane transport GO:0055085 399 0.026
glycolipid metabolic process GO:0006664 27 0.026
regulation of protein targeting GO:1903533 91 0.026
regulation of membrane permeability GO:0090559 25 0.026
regulation of leukocyte proliferation GO:0070663 67 0.025
negative regulation of calcium ion transmembrane transport GO:1903170 11 0.025
nucleotide catabolic process GO:0009166 408 0.025
heart morphogenesis GO:0003007 48 0.025
regulation of cell shape GO:0008360 48 0.025
microtubule based process GO:0007017 210 0.025
regulation of hormone secretion GO:0046883 57 0.024
termination of rna polymerase ii transcription GO:0006369 1 0.024
replication fork processing GO:0031297 13 0.024
glycerophospholipid metabolic process GO:0006650 84 0.024
segmentation GO:0035282 4 0.023
negative regulation of jnk cascade GO:0046329 16 0.023
liposaccharide metabolic process GO:1903509 27 0.023
negative regulation of protein phosphorylation GO:0001933 140 0.023
axon development GO:0061564 34 0.023
organophosphate catabolic process GO:0046434 430 0.023
regulation of ras protein signal transduction GO:0046578 155 0.022
actin cytoskeleton organization GO:0030036 207 0.022
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.022
response to growth factor GO:0070848 205 0.022
regulation of generation of precursor metabolites and energy GO:0043467 27 0.022
Rat
regulation of sequestering of calcium ion GO:0051282 41 0.022
establishment of protein localization to organelle GO:0072594 172 0.022
somatic muscle development GO:0007525 1 0.021
central nervous system projection neuron axonogenesis GO:0021952 3 0.021
regulation of ion transmembrane transporter activity GO:0032412 72 0.021
response to organic cyclic compound GO:0014070 204 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
regulation of actin filament polymerization GO:0030833 50 0.021
regulation of voltage gated calcium channel activity GO:1901385 7 0.021
negative regulation of protein transport GO:0051224 75 0.021
protein targeting to nucleus GO:0044744 104 0.021

PPP1CA disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.603
disease of cellular proliferation DOID:14566 174 0.603
organ system cancer DOID:0050686 164 0.603