Homo sapiens

25 known processes

WBP4

WW domain binding protein 4 (formin binding protein 21)

(Aliases: FBP21,MGC117310)

WBP4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of meiosis GO:0040020 3 0.932
regulation of meiotic cell cycle GO:0051445 4 0.903
rna splicing via transesterification reactions GO:0000375 90 0.771
mrna splicing via spliceosome GO:0000398 89 0.729
positive regulation of cellular component organization GO:0051130 376 0.692
mrna processing GO:0006397 133 0.575
organelle fission GO:0048285 149 0.570
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.501
rna processing GO:0006396 255 0.500
negative regulation of oxidative stress induced cell death GO:1903202 17 0.467
regulation of nuclear division GO:0051783 65 0.446
cell development GO:0048468 328 0.429
mitotic cell cycle GO:0000278 326 0.418
regulation of cell division GO:0051302 116 0.409
regulation of cell cycle GO:0051726 393 0.389
sensory perception of light stimulus GO:0050953 35 0.348
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.301
intrinsic apoptotic signaling pathway GO:0097193 127 0.266
cell death in response to oxidative stress GO:0036473 29 0.242
cell division GO:0051301 168 0.231
positive regulation of response to oxidative stress GO:1902884 7 0.217
negative regulation of apoptotic process GO:0043066 316 0.201
positive regulation of organelle organization GO:0010638 195 0.201
alternative mrna splicing via spliceosome GO:0000380 27 0.191
regulation of oxidative stress induced cell death GO:1903201 24 0.187
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.178
regulation of response to oxidative stress GO:1902882 26 0.175
meiotic nuclear division GO:0007126 10 0.171
regulation of mrna splicing via spliceosome GO:0048024 32 0.164
system process GO:0003008 349 0.156
positive regulation of transport GO:0051050 336 0.152
mitotic cell cycle phase transition GO:0044772 162 0.150
cellular response to oxidative stress GO:0034599 85 0.148
nervous system development GO:0007399 293 0.139
rna splicing GO:0008380 131 0.139
sensory perception GO:0007600 103 0.130
mrna metabolic process GO:0016071 175 0.123
female gamete generation GO:0007292 2 0.122
multicellular organismal aging GO:0010259 3 0.120
regulation of homeostatic process GO:0032844 121 0.118
organelle assembly GO:0070925 176 0.108
negative regulation of cellular response to oxidative stress GO:1900408 18 0.108
positive regulation of apoptotic signaling pathway GO:2001235 70 0.106
actin filament based process GO:0030029 224 0.106
negative regulation of response to oxidative stress GO:1902883 18 0.105
neurological system process GO:0050877 163 0.105
purine nucleoside catabolic process GO:0006152 398 0.105
oogenesis GO:0048477 2 0.103
visual perception GO:0007601 27 0.102
negative regulation of cell death GO:0060548 345 0.102
nuclear division GO:0000280 128 0.099
mitotic nuclear division GO:0007067 119 0.098
response to oxidative stress GO:0006979 121 0.097
positive regulation of programmed cell death GO:0043068 249 0.095
mitotic cell cycle process GO:1903047 286 0.086
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.080
regulation of cellular response to oxidative stress GO:1900407 26 0.080
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.077
myosin filament assembly GO:0031034 2 0.069
small gtpase mediated signal transduction GO:0007264 78 0.067
meiotic cell cycle GO:0051321 13 0.066
regulation of mitotic cell cycle phase transition GO:1901990 118 0.064
regulation of growth GO:0040008 165 0.063
Worm
microtubule based process GO:0007017 210 0.062
reproductive process GO:0022414 106 0.062
Worm
embryo development GO:0009790 123 0.060
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.059
regulation of cell morphogenesis GO:0022604 153 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.058
cellular macromolecular complex assembly GO:0034622 324 0.057
cellular component morphogenesis GO:0032989 314 0.056
negative regulation of apoptotic signaling pathway GO:2001234 97 0.055
protein processing GO:0016485 226 0.055
regulation of cell projection organization GO:0031344 107 0.054
positive regulation of apoptotic process GO:0043065 246 0.054
multicellular organismal reproductive process GO:0048609 40 0.054
developmental process involved in reproduction GO:0003006 66 0.053
Worm
regulation of actin filament based process GO:0032970 141 0.053
positive regulation of cell death GO:0010942 263 0.052
microtubule cytoskeleton organization GO:0000226 176 0.052
interspecies interaction between organisms GO:0044419 156 0.052
reproduction GO:0000003 63 0.051
Worm
cellular response to dna damage stimulus GO:0006974 379 0.051
positive regulation of cellular component biogenesis GO:0044089 158 0.050
protein localization to organelle GO:0033365 280 0.048
neuromuscular junction development GO:0007528 3 0.048
atp catabolic process GO:0006200 157 0.048
neuron projection development GO:0031175 106 0.047
posttranscriptional regulation of gene expression GO:0010608 213 0.047
rna interference GO:0016246 4 0.047
regulation of oxidative stress induced neuron death GO:1903203 9 0.045
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.044
nucleoside catabolic process GO:0009164 408 0.044
endocytosis GO:0006897 159 0.044
regulation of cell cycle phase transition GO:1901987 126 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
muscle system process GO:0003012 81 0.043
viral process GO:0016032 146 0.043
growth GO:0040007 202 0.042
Worm
positive regulation of cytoplasmic transport GO:1903651 82 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.042
negative regulation of protein maturation GO:1903318 142 0.041
nitrogen compound transport GO:0071705 191 0.041
single organism reproductive process GO:0044702 98 0.040
Worm
metaphase anaphase transition of cell cycle GO:0044784 21 0.040
multi organism reproductive process GO:0044703 54 0.039
neuron death GO:0070997 65 0.039
response to abiotic stimulus GO:0009628 336 0.038
vesicle mediated transport GO:0016192 371 0.038
regulation of cellular component biogenesis GO:0044087 281 0.038
chromosome separation GO:0051304 23 0.037
negative regulation of programmed cell death GO:0043069 321 0.037
purine nucleotide catabolic process GO:0006195 405 0.036
regulation of proteolysis GO:0030162 293 0.036
negative regulation of cell cycle process GO:0010948 121 0.036
apoptotic signaling pathway GO:0097190 268 0.035
response to radiation GO:0009314 151 0.034
covalent chromatin modification GO:0016569 254 0.034
positive regulation of chromosome organization GO:2001252 41 0.033
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.033
regulation of protein processing GO:0070613 150 0.033
regulation of mitotic sister chromatid separation GO:0010965 27 0.033
cellular protein complex assembly GO:0043623 188 0.033
regulation of receptor mediated endocytosis GO:0048259 32 0.033
defense response GO:0006952 315 0.033
organophosphate catabolic process GO:0046434 430 0.033
hematopoietic stem cell differentiation GO:0060218 4 0.032
positive regulation of intracellular transport GO:0032388 104 0.032
negative regulation of protein processing GO:0010955 142 0.032
negative regulation of cellular component organization GO:0051129 235 0.031
wnt signaling pathway GO:0016055 156 0.031
multicellular organism reproduction GO:0032504 42 0.031
actin filament based movement GO:0030048 17 0.030
negative regulation of oxidative stress induced neuron death GO:1903204 7 0.030
ribonucleotide catabolic process GO:0009261 405 0.030
cellular ketone metabolic process GO:0042180 80 0.030
regulation of protein complex assembly GO:0043254 147 0.030
regulation of intracellular transport GO:0032386 195 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.030
regulation of cytoplasmic transport GO:1903649 149 0.030
negative regulation of protein metabolic process GO:0051248 391 0.029
maintenance of location GO:0051235 112 0.029
cell projection morphogenesis GO:0048858 129 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.029
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.029
amine metabolic process GO:0009308 44 0.029
regulation of gene expression epigenetic GO:0040029 73 0.028
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903377 5 0.028
sex differentiation GO:0007548 45 0.028
Worm
regulation of cellular protein catabolic process GO:1903362 96 0.027
regulation of cytoskeleton organization GO:0051493 177 0.027
cellular homeostasis GO:0019725 196 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
regulation of chromosome organization GO:0033044 103 0.026
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.026
striated muscle myosin thick filament assembly GO:0071688 2 0.025
cell cycle phase transition GO:0044770 173 0.025
double strand break repair GO:0006302 101 0.025
negative regulation of proteolysis GO:0045861 132 0.025
cytoplasmic transport GO:0016482 379 0.024
cell morphogenesis GO:0000902 296 0.024
actin filament bundle organization GO:0061572 54 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
negative regulation of neuron apoptotic process GO:0043524 23 0.024
protein polymerization GO:0051258 71 0.024
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.023
oocyte differentiation GO:0009994 2 0.023
actomyosin structure organization GO:0031032 59 0.023
sister chromatid segregation GO:0000819 54 0.023
negative regulation of cell cycle GO:0045786 193 0.023
regulation of nucleocytoplasmic transport GO:0046822 98 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
ribonucleoside catabolic process GO:0042454 406 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
regulation of cellular response to stress GO:0080135 244 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
defense response to bacterium GO:0042742 63 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.020
receptor mediated endocytosis GO:0006898 84 0.020
meiosis i GO:0007127 4 0.020
spermatid development GO:0007286 4 0.020
ribonucleoprotein complex assembly GO:0022618 78 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
regulation of protein maturation GO:1903317 150 0.020
divalent inorganic cation homeostasis GO:0072507 136 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
actin filament bundle assembly GO:0051017 54 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
ras protein signal transduction GO:0007265 73 0.019
mitotic sister chromatid separation GO:0051306 18 0.019
positive regulation of nervous system development GO:0051962 54 0.019
stress fiber assembly GO:0043149 40 0.019
post embryonic development GO:0009791 2 0.019
Worm
protein stabilization GO:0050821 64 0.018
negative regulation of cell cycle phase transition GO:1901988 89 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.017
generation of neurons GO:0048699 152 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.017
metal ion homeostasis GO:0055065 169 0.017
modification of morphology or physiology of other organism GO:0035821 43 0.017
regulation of sister chromatid segregation GO:0033045 27 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
regulation of chromosome segregation GO:0051983 44 0.016
innate immune response GO:0045087 178 0.016
regulation of mitosis GO:0007088 63 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.016
nucleus localization GO:0051647 1 0.016
regulation of organelle assembly GO:1902115 40 0.016
cell projection assembly GO:0030031 126 0.016
regulation of rna splicing GO:0043484 62 0.015
positive regulation of neurogenesis GO:0050769 49 0.015
cell part morphogenesis GO:0032990 137 0.015
maintenance of protein location in cell GO:0032507 56 0.015
endosomal transport GO:0016197 129 0.015
receptor metabolic process GO:0043112 81 0.015
intracellular protein transport GO:0006886 270 0.015
negative regulation of developmental process GO:0051093 247 0.015
cell growth GO:0016049 160 0.015
regulation of circadian rhythm GO:0042752 11 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.015
regulation of ion homeostasis GO:2000021 73 0.015
ribonucleoprotein complex subunit organization GO:0071826 81 0.015
regulation of endocytosis GO:0030100 72 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
actin cytoskeleton organization GO:0030036 207 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
cell activation GO:0001775 213 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
cation transport GO:0006812 331 0.014
endodermal cell fate commitment GO:0001711 4 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
lipid biosynthetic process GO:0008610 177 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
mitotic spindle organization GO:0007052 27 0.014
regulation of cellular component movement GO:0051270 334 0.013
cell projection organization GO:0030030 252 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
viral life cycle GO:0019058 132 0.013
regulation of protein catabolic process GO:0042176 155 0.013
behavior GO:0007610 112 0.013
developmental growth involved in morphogenesis GO:0060560 23 0.013
response to uv GO:0009411 73 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.013
regulation of protein transport GO:0051223 213 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
protein maturation GO:0051604 233 0.013
regulation of cell cycle process GO:0010564 266 0.012
positive regulation of intracellular protein transport GO:0090316 76 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
chromatin organization GO:0006325 351 0.012
nucleotide catabolic process GO:0009166 408 0.012
neuron apoptotic process GO:0051402 39 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
oocyte development GO:0048599 1 0.012
sequestering of metal ion GO:0051238 24 0.012
tissue regeneration GO:0042246 3 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
sequestering of calcium ion GO:0051208 17 0.012
protein localization to cytoskeleton GO:0044380 11 0.012
positive regulation of oxidative stress induced cell death GO:1903209 5 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
neuroblast proliferation GO:0007405 4 0.011
single organism membrane organization GO:0044802 268 0.011
memory GO:0007613 3 0.011
regulation of dna metabolic process GO:0051052 153 0.011
cell adhesion GO:0007155 325 0.011
regulation of neuron death GO:1901214 56 0.011
negative regulation of peptidase activity GO:0010466 91 0.011
regulation of protein stability GO:0031647 87 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
actin filament organization GO:0007015 128 0.011
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.010
determination of adult lifespan GO:0008340 2 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
gamete generation GO:0007276 25 0.010
muscle contraction GO:0006936 73 0.010
wound healing GO:0042060 115 0.010
protein polyubiquitination GO:0000209 110 0.010
spindle organization GO:0007051 53 0.010
chromatin modification GO:0016568 298 0.010
regulation of neuron projection development GO:0010975 57 0.010
regulation of anatomical structure size GO:0090066 101 0.010
axon extension GO:0048675 13 0.010
chemical homeostasis GO:0048878 306 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010

WBP4 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.029
nervous system disease DOID:863 431 0.029
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.019
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
neurodegenerative disease DOID:1289 102 0.015
gastrointestinal system cancer DOID:3119 52 0.014