Homo sapiens

0 known processes

KLK11

kallikrein-related peptidase 11

(Aliases: MGC33060,PRSS20,TLSP)

KLK11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
insemination GO:0007320 1 0.927
Human
seminal clot liquefaction GO:0070684 1 0.903
Human
copulation GO:0007620 1 0.902
Human
epidermis morphogenesis GO:0048730 3 0.878
Human
skin development GO:0043588 76 0.500
Human
mating GO:0007618 1 0.335
Human
keratinization GO:0031424 2 0.305
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 9 0.256
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.201
Human
epithelium development GO:0060429 227 0.191
Human
epidermis development GO:0008544 59 0.189
Human
hair follicle morphogenesis GO:0031069 2 0.186
protein maturation GO:0051604 233 0.158
Human
protein processing GO:0016485 226 0.128
Human
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.124
Human
zymogen activation GO:0031638 70 0.098
Human
epithelial cell migration GO:0010631 119 0.096
Human
epithelial cell differentiation GO:0030855 141 0.088
epithelium migration GO:0090132 119 0.083
Human
endothelial cell migration GO:0043542 86 0.082
Human
keratinocyte differentiation GO:0030216 36 0.072
ameboidal type cell migration GO:0001667 135 0.066
Human
tissue migration GO:0090130 119 0.062
Human
post embryonic development GO:0009791 2 0.062
organ morphogenesis GO:0009887 147 0.056
Human
system process GO:0003008 349 0.056
cellular ketone metabolic process GO:0042180 80 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.045
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.044
Human
small gtpase mediated signal transduction GO:0007264 78 0.042
response to biotic stimulus GO:0009607 276 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
regulation of locomotion GO:0040012 329 0.039
morphogenesis of an epithelium GO:0002009 60 0.038
Human
negative regulation of apoptotic process GO:0043066 316 0.038
inorganic ion transmembrane transport GO:0098660 231 0.037
cytoplasmic transport GO:0016482 379 0.037
ion transmembrane transport GO:0034220 338 0.037
multicellular organismal aging GO:0010259 3 0.036
negative regulation of cell death GO:0060548 345 0.035
response to oxygen containing compound GO:1901700 369 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
cellular amine metabolic process GO:0044106 41 0.035
chemical homeostasis GO:0048878 306 0.033
lipid metabolic process GO:0006629 381 0.033
skin morphogenesis GO:0043589 6 0.033
Human
response to organic cyclic compound GO:0014070 204 0.032
negative regulation of programmed cell death GO:0043069 321 0.032
determination of adult lifespan GO:0008340 2 0.032
response to external biotic stimulus GO:0043207 261 0.031
cardiac muscle cell contraction GO:0086003 4 0.031
odontogenesis GO:0042476 25 0.030
Human
cellular amino acid metabolic process GO:0006520 116 0.030
regulation of cellular component movement GO:0051270 334 0.030
transmembrane transport GO:0055085 399 0.030
response to other organism GO:0051707 261 0.030
cellular lipid metabolic process GO:0044255 303 0.029
tissue morphogenesis GO:0048729 96 0.029
Human
response to hormone GO:0009725 175 0.029
regeneration GO:0031099 4 0.028
cell adhesion GO:0007155 325 0.028
negative regulation of protein processing GO:0010955 142 0.028
neuron death GO:0070997 65 0.028
Human
amine metabolic process GO:0009308 44 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
ion homeostasis GO:0050801 230 0.026
response to lipid GO:0033993 206 0.026
positive regulation of phosphorylation GO:0042327 394 0.026
positive regulation of transport GO:0051050 336 0.026
defense response GO:0006952 315 0.026
protein localization to organelle GO:0033365 280 0.025
vesicle mediated transport GO:0016192 371 0.025
regulation of peptidase activity GO:0052547 180 0.025
intracellular protein transport GO:0006886 270 0.025
regulation of proteolysis GO:0030162 293 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
regulation of protein maturation GO:1903317 150 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
av node cell to bundle of his cell communication by electrical coupling GO:0086053 1 0.024
single organism cellular localization GO:1902580 332 0.024
positive regulation of immune system process GO:0002684 283 0.023
regulation of cell cycle process GO:0010564 266 0.023
regulation of membrane potential GO:0042391 95 0.023
regulation of protein processing GO:0070613 150 0.022
fertilization GO:0009566 12 0.022
Human
anatomical structure homeostasis GO:0060249 100 0.022
organelle assembly GO:0070925 176 0.022
cardiac muscle contraction GO:0060048 34 0.021
female gamete generation GO:0007292 2 0.021
cation homeostasis GO:0055080 189 0.021
odontogenesis of dentin containing tooth GO:0042475 10 0.021
Human
negative regulation of peptidase activity GO:0010466 91 0.021
golgi to plasma membrane cftr protein transport GO:0043000 1 0.021
striated muscle contraction GO:0006941 52 0.021
regulation of cell cycle GO:0051726 393 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of cell adhesion GO:0030155 166 0.020
regulation of protein localization GO:0032880 296 0.020
immune response GO:0006955 307 0.020
hair cycle GO:0042633 28 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
response to inorganic substance GO:0010035 127 0.020
regulation of cell migration GO:0030334 289 0.020
membrane organization GO:0061024 292 0.020
retina homeostasis GO:0001895 42 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
negative regulation of proteolysis GO:0045861 132 0.020
cellular macromolecular complex assembly GO:0034622 324 0.019
regulation of body fluid levels GO:0050878 99 0.019
oogenesis GO:0048477 2 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
regulation of multi organism process GO:0043900 157 0.018
response to fungus GO:0009620 4 0.018
mitotic cell cycle GO:0000278 326 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
humoral immune response GO:0006959 49 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
regulation of growth GO:0040008 165 0.017
sequestering of metal ion GO:0051238 24 0.017
wnt signaling pathway GO:0016055 156 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
cell growth GO:0016049 160 0.017
negative regulation of cell motility GO:2000146 104 0.017
negative regulation of endopeptidase activity GO:0010951 84 0.017
secretion by cell GO:0032940 226 0.017
negative regulation of interferon gamma secretion GO:1902714 1 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
epidermal cell differentiation GO:0009913 45 0.017
negative regulation of protein maturation GO:1903318 142 0.017
muscle system process GO:0003012 81 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of secretion GO:0051046 194 0.017
organophosphate catabolic process GO:0046434 430 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
regulation of intracellular transport GO:0032386 195 0.016
response to abiotic stimulus GO:0009628 336 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
tissue regeneration GO:0042246 3 0.016
cellular component morphogenesis GO:0032989 314 0.016
spermatid differentiation GO:0048515 4 0.016
fatty acid metabolic process GO:0006631 115 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
sensory perception GO:0007600 103 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
cellular protein complex assembly GO:0043623 188 0.016
innate immune response GO:0045087 178 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
actin mediated cell contraction GO:0070252 12 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
oocyte development GO:0048599 1 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
cation transmembrane transport GO:0098655 238 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
water homeostasis GO:0030104 14 0.016
regulation of cell motility GO:2000145 299 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
cell division GO:0051301 168 0.016
dephosphorylation GO:0016311 209 0.016
carbohydrate metabolic process GO:0005975 207 0.016
positive regulation of hydrolase activity GO:0051345 331 0.015
single organism reproductive process GO:0044702 98 0.015
Human
nucleoside phosphate catabolic process GO:1901292 412 0.015
regulation of protein transport GO:0051223 213 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
mapk cascade GO:0000165 288 0.015
maintenance of location GO:0051235 112 0.015
cell morphogenesis GO:0000902 296 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
compound eye development GO:0048749 1 0.015
pulmonary valve formation GO:0003193 1 0.015
intermediate filament based process GO:0045103 17 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
locomotory behavior GO:0007626 1 0.015
purine containing compound catabolic process GO:0072523 411 0.015
wound healing GO:0042060 115 0.015
cell substrate adhesion GO:0031589 132 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
actin filament based movement GO:0030048 17 0.015
cardiovascular system development GO:0072358 262 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
response to cytokine GO:0034097 232 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
negative regulation of cell cycle GO:0045786 193 0.015
mitotic cell cycle process GO:1903047 286 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
response to virus GO:0009615 126 0.014
biological adhesion GO:0022610 331 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
sex determination GO:0007530 3 0.014
epithelial cell proliferation GO:0050673 128 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
anion transport GO:0006820 161 0.014
growth GO:0040007 202 0.014
response to oxidative stress GO:0006979 121 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
nucleotide catabolic process GO:0009166 408 0.014
protein catabolic process GO:0030163 325 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
single organism membrane organization GO:0044802 268 0.014
segmentation GO:0035282 4 0.014
actin filament based process GO:0030029 224 0.014
endomembrane system organization GO:0010256 196 0.014
protein targeting GO:0006605 187 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
oxidation reduction process GO:0055114 396 0.013
reproductive process GO:0022414 106 0.013
Human
spermatid development GO:0007286 4 0.013
protein oligomerization GO:0051259 173 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
cell projection organization GO:0030030 252 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
negative regulation of developmental process GO:0051093 247 0.013
positive regulation of cell death GO:0010942 263 0.013
tissue homeostasis GO:0001894 63 0.013
positive regulation of tooth mineralization GO:0070172 2 0.013
regulation of cytokine production GO:0001817 232 0.013
metal ion homeostasis GO:0055065 169 0.013
lipid biosynthetic process GO:0008610 177 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
response to bacterium GO:0009617 144 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of transferase activity GO:0051338 355 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
positive regulation of catabolic process GO:0009896 310 0.013
positive regulation of developmental process GO:0051094 314 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of protein transport GO:0051222 135 0.012
taxis GO:0042330 157 0.012
rhythmic behavior GO:0007622 2 0.012
neuromuscular junction development GO:0007528 3 0.012
regulation of kinase activity GO:0043549 314 0.012
negative regulation of cellular component movement GO:0051271 106 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
blastoderm segmentation GO:0007350 2 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
calcium ion homeostasis GO:0055074 122 0.012
lipoxygenase pathway GO:0019372 4 0.012
mitochondrion organization GO:0007005 156 0.012
angiogenesis GO:0001525 147 0.012
microtubule based process GO:0007017 210 0.012
cellular calcium ion homeostasis GO:0006874 117 0.012
defense response to fungus GO:0050832 4 0.012
startle response GO:0001964 3 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
response to axon injury GO:0048678 1 0.012
neurological system process GO:0050877 163 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
anterior posterior axis specification GO:0009948 2 0.012
defense response to other organism GO:0098542 129 0.012
oocyte differentiation GO:0009994 2 0.012
tongue development GO:0043586 1 0.012
regulation of cellular response to stress GO:0080135 244 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
action potential GO:0001508 34 0.012
cellular response to organonitrogen compound GO:0071417 124 0.012
cation transport GO:0006812 331 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
regulation of mapk cascade GO:0043408 262 0.012
complement activation GO:0006956 19 0.012
nucleoside catabolic process GO:0009164 408 0.012
muscle contraction GO:0006936 73 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
cellular cation homeostasis GO:0030003 163 0.012
cell activation GO:0001775 213 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
chloride transmembrane transport GO:1902476 38 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
regulation of actin filament based process GO:0032970 141 0.011
sequestering of calcium ion GO:0051208 17 0.011
sodium ion transport GO:0006814 61 0.011
immune effector process GO:0002252 159 0.011
regulation of protein stability GO:0031647 87 0.011
protein localization to plasma membrane GO:0072659 93 0.011
ossification GO:0001503 121 0.011
regulation of cell differentiation GO:0045595 393 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
alcohol metabolic process GO:0006066 114 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
regulation of protein complex assembly GO:0043254 147 0.011
regulation of immune response GO:0050776 201 0.011
small molecule biosynthetic process GO:0044283 157 0.011
protein homooligomerization GO:0051260 100 0.011
apoptotic signaling pathway GO:0097190 268 0.011
hepoxilin metabolic process GO:0051121 1 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
regulation of response to external stimulus GO:0032101 222 0.011
establishment of planar polarity GO:0001736 3 0.011
interspecies interaction between organisms GO:0044419 156 0.011
protein import GO:0017038 130 0.011
negative regulation of transport GO:0051051 176 0.011
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.011
leukotriene a4 metabolic process GO:1901751 1 0.011
endocytosis GO:0006897 159 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
sodium ion transmembrane transport GO:0035725 59 0.011
regulation of protein localization to nucleus GO:1900180 85 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
negative regulation of protein modification process GO:0031400 200 0.011
icosanoid metabolic process GO:0006690 35 0.011
cuticle development GO:0042335 1 0.011
viral life cycle GO:0019058 132 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
tube development GO:0035295 125 0.011
blood vessel development GO:0001568 172 0.011
av node cell to bundle of his cell communication GO:0086067 4 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
golgi vesicle transport GO:0048193 80 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
cellular homeostasis GO:0019725 196 0.011
positive regulation of locomotion GO:0040017 186 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
cellular protein catabolic process GO:0044257 261 0.011
neural tube formation GO:0001841 3 0.010
vasculature development GO:0001944 181 0.010
response to radiation GO:0009314 151 0.010
regulation of cell growth GO:0001558 135 0.010
positive regulation of organelle organization GO:0010638 195 0.010
cell projection assembly GO:0030031 126 0.010
cellular chemical homeostasis GO:0055082 180 0.010
divalent inorganic cation transport GO:0072511 158 0.010
multi organism cellular process GO:0044764 156 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
negative regulation of cell growth GO:0030308 83 0.010
glycosyl compound catabolic process GO:1901658 413 0.010
single organism cell adhesion GO:0098602 179 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
cellular ion homeostasis GO:0006873 168 0.010
negative regulation of growth GO:0045926 97 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
cellular response to lipid GO:0071396 127 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
isoprenoid metabolic process GO:0006720 39 0.010
activation of immune response GO:0002253 114 0.010
nuclear transport GO:0051169 179 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
immune system development GO:0002520 195 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
positive regulation of cell migration GO:0030335 172 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
defense response to bacterium GO:0042742 63 0.010
memory GO:0007613 3 0.010
viral process GO:0016032 146 0.010
cellular response to oxidative stress GO:0034599 85 0.010
nuclear import GO:0051170 106 0.010

KLK11 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030
disease of metabolism DOID:0014667 295 0.018
retinal disease DOID:5679 118 0.016
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
central nervous system disease DOID:331 186 0.012
skin disease DOID:37 33 0.012
integumentary system disease DOID:16 43 0.012
bone disease DOID:0080001 88 0.012
musculoskeletal system disease DOID:17 223 0.012
connective tissue disease DOID:65 109 0.012