Homo sapiens

53 known processes

UBR1

ubiquitin protein ligase E3 component n-recognin 1

(Aliases: MGC142065,JBS,MGC142067)

UBR1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of camp mediated signaling GO:0043951 4 0.972
cellular response to endogenous stimulus GO:0071495 336 0.929
response to amino acid GO:0043200 14 0.925
limbic system development GO:0021761 3 0.913
cellular amine metabolic process GO:0044106 41 0.897
cellular response to amino acid stimulus GO:0071230 12 0.708
cellular macromolecule catabolic process GO:0044265 380 0.678
Mouse
positive regulation of reciprocal meiotic recombination GO:0010845 1 0.646
negative regulation of catalytic activity GO:0043086 335 0.592
vasculature development GO:0001944 181 0.590
defense response to bacterium GO:0042742 63 0.569
endosomal transport GO:0016197 129 0.563
amine metabolic process GO:0009308 44 0.563
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.553
forebrain development GO:0030900 26 0.518
regulation of protein complex assembly GO:0043254 147 0.516
positive regulation of cellular component organization GO:0051130 376 0.493
gtp metabolic process GO:0046039 239 0.469
regulation of cellular component biogenesis GO:0044087 281 0.460
positive regulation of protein complex assembly GO:0031334 86 0.432
endocytic recycling GO:0032456 12 0.421
nucleoside phosphate catabolic process GO:1901292 412 0.411
regulation of gtp catabolic process GO:0033124 180 0.402
regulation of gtpase activity GO:0043087 180 0.398
microtubule cytoskeleton organization GO:0000226 176 0.378
head development GO:0060322 108 0.362
microtubule based process GO:0007017 210 0.358
cerebellum development GO:0021549 2 0.335
tor signaling GO:0031929 39 0.326
regulation of nucleoside metabolic process GO:0009118 209 0.323
cellular ketone metabolic process GO:0042180 80 0.309
hindbrain development GO:0030902 3 0.306
positive regulation of organelle organization GO:0010638 195 0.300
defense response GO:0006952 315 0.295
negative regulation of histone phosphorylation GO:0033128 2 0.290
histone h2a ubiquitination GO:0033522 17 0.284
sensory perception of smell GO:0007608 2 0.282
protein catabolic process GO:0030163 325 0.258
Mouse
regulation of tor signaling GO:0032006 30 0.257
purine nucleoside catabolic process GO:0006152 398 0.256
post embryonic development GO:0009791 2 0.248
brain development GO:0007420 97 0.247
regulation of protein polymerization GO:0032271 63 0.243
anatomical structure formation involved in morphogenesis GO:0048646 284 0.240
regulation of cellular amine metabolic process GO:0033238 11 0.230
modification dependent macromolecule catabolic process GO:0043632 212 0.216
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.214
negative regulation of apoptotic signaling pathway GO:2001234 97 0.214
blood vessel morphogenesis GO:0048514 162 0.212
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.208
response to other organism GO:0051707 261 0.205
cellular protein complex assembly GO:0043623 188 0.204
immune effector process GO:0002252 159 0.203
axoneme assembly GO:0035082 3 0.200
protein polymerization GO:0051258 71 0.199
regulation of cellular component size GO:0032535 82 0.194
canonical wnt signaling pathway GO:0060070 116 0.194
neural tube patterning GO:0021532 2 0.187
modification dependent protein catabolic process GO:0019941 209 0.184
Mouse
spermatid differentiation GO:0048515 4 0.184
glycosyl compound catabolic process GO:1901658 413 0.177
metencephalon development GO:0022037 2 0.174
regulation of transferase activity GO:0051338 355 0.174
female gamete generation GO:0007292 2 0.174
response to acid chemical GO:0001101 66 0.166
response to leucine GO:0043201 2 0.163
organophosphate catabolic process GO:0046434 430 0.163
cerebral cortex development GO:0021987 10 0.162
negative regulation of protein phosphorylation GO:0001933 140 0.159
regulation of cellular ketone metabolic process GO:0010565 50 0.156
response to external biotic stimulus GO:0043207 261 0.155
cellular response to oxygen containing compound GO:1901701 276 0.155
intraciliary transport GO:0042073 7 0.151
double strand break repair GO:0006302 101 0.151
regulation of cellular amino acid metabolic process GO:0006521 6 0.149
regulation of actin filament polymerization GO:0030833 50 0.148
guanosine containing compound metabolic process GO:1901068 244 0.147
telencephalon development GO:0021537 17 0.144
guanosine containing compound catabolic process GO:1901069 239 0.144
positive regulation of gtp catabolic process GO:0033126 166 0.142
response to organonitrogen compound GO:0010243 156 0.138
regulation of chromosome organization GO:0033044 103 0.135
response to drug GO:0042493 81 0.133
organelle fission GO:0048285 149 0.133
spinal cord development GO:0021510 4 0.131
regulation of cell motility GO:2000145 299 0.131
negative regulation of cellular component organization GO:0051129 235 0.130
positive regulation of protein kinase activity GO:0045860 190 0.130
ribonucleoside triphosphate metabolic process GO:0009199 412 0.130
positive regulation of dna metabolic process GO:0051054 73 0.124
purine nucleoside triphosphate metabolic process GO:0009144 412 0.124
actin filament polymerization GO:0030041 45 0.124
chromatin modification GO:0016568 298 0.123
regulation of proteolysis GO:0030162 293 0.123
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.122
cellular macromolecular complex assembly GO:0034622 324 0.122
negative regulation of organelle organization GO:0010639 126 0.121
central nervous system development GO:0007417 123 0.121
nucleotide catabolic process GO:0009166 408 0.121
regulation of reciprocal meiotic recombination GO:0010520 1 0.121
regulation of protein kinase activity GO:0045859 289 0.120
vesicle mediated transport GO:0016192 371 0.120
regulation of anatomical structure size GO:0090066 101 0.120
positive regulation of cellular component biogenesis GO:0044089 158 0.118
meiosis i GO:0007127 4 0.118
biological adhesion GO:0022610 331 0.117
purine ribonucleoside catabolic process GO:0046130 398 0.116
circulatory system development GO:0072359 262 0.115
centrosome cycle GO:0007098 32 0.115
mitotic cell cycle process GO:1903047 286 0.111
ribonucleoside catabolic process GO:0042454 406 0.110
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.107
ribonucleotide catabolic process GO:0009261 405 0.107
response to biotic stimulus GO:0009607 276 0.106
nucleoside triphosphate metabolic process GO:0009141 422 0.105
negative regulation of response to dna damage stimulus GO:2001021 33 0.105
chromatin organization GO:0006325 351 0.104
cardiovascular system development GO:0072358 262 0.104
cellular response to nitrogen compound GO:1901699 144 0.104
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.101
apoptotic signaling pathway GO:0097190 268 0.101
cell development GO:0048468 328 0.101
regulation of cellular protein catabolic process GO:1903362 96 0.100
negative regulation of hydrolase activity GO:0051346 182 0.100
positive regulation of transferase activity GO:0051347 227 0.100
protein k63 linked ubiquitination GO:0070534 31 0.099
negative regulation of phosphorylation GO:0042326 174 0.098
nucleoside catabolic process GO:0009164 408 0.097
positive regulation of intracellular transport GO:0032388 104 0.096
protein polyubiquitination GO:0000209 110 0.095
regulation of nucleotide catabolic process GO:0030811 205 0.095
centrosome separation GO:0051299 3 0.094
positive regulation of protein phosphorylation GO:0001934 313 0.094
purine nucleoside triphosphate catabolic process GO:0009146 392 0.094
single organism cell adhesion GO:0098602 179 0.093
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.093
mitotic cell cycle GO:0000278 326 0.092
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.092
centrosome organization GO:0051297 58 0.090
response to hormone GO:0009725 175 0.089
telomere maintenance via recombination GO:0000722 4 0.089
single organism reproductive process GO:0044702 98 0.088
positive regulation of cellular amine metabolic process GO:0033240 7 0.088
single organismal cell cell adhesion GO:0016337 148 0.087
response to uv GO:0009411 73 0.086
protein k11 linked ubiquitination GO:0070979 24 0.086
regeneration GO:0031099 4 0.085
regulation of mitotic cell cycle phase transition GO:1901990 118 0.084
positive regulation of catabolic process GO:0009896 310 0.084
negative regulation of protein kinase activity GO:0006469 98 0.083
protein autoubiquitination GO:0051865 37 0.083
response to growth factor GO:0070848 205 0.082
regulation of proteasomal protein catabolic process GO:0061136 87 0.081
spermatid development GO:0007286 4 0.081
cell adhesion GO:0007155 325 0.081
positive regulation of protein polymerization GO:0032273 45 0.081
regulation of kinase activity GO:0043549 314 0.081
regulation of apoptotic signaling pathway GO:2001233 175 0.081
purine containing compound catabolic process GO:0072523 411 0.080
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.079
positive regulation of cellular protein catabolic process GO:1903364 37 0.079
cellular response to dna damage stimulus GO:0006974 379 0.079
regulation of dna metabolic process GO:0051052 153 0.078
urogenital system development GO:0001655 65 0.075
brain morphogenesis GO:0048854 1 0.075
cilium organization GO:0044782 68 0.075
regulation of response to dna damage stimulus GO:2001020 94 0.074
cellular protein catabolic process GO:0044257 261 0.074
Mouse
cell morphogenesis GO:0000902 296 0.073
negative regulation of protein modification process GO:0031400 200 0.072
segmentation GO:0035282 4 0.071
cellular response to acid chemical GO:0071229 44 0.071
purine nucleotide catabolic process GO:0006195 405 0.069
locomotory behavior GO:0007626 1 0.069
negative regulation of phosphorus metabolic process GO:0010563 267 0.068
neuromuscular junction development GO:0007528 3 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.067
demethylation GO:0070988 37 0.066
positive regulation of nucleotide metabolic process GO:0045981 230 0.066
telomere organization GO:0032200 33 0.066
ubiquitin dependent protein catabolic process GO:0006511 206 0.065
Mouse
dna recombination GO:0006310 77 0.065
kidney development GO:0001822 53 0.064
protein homooligomerization GO:0051260 100 0.063
peptidyl serine phosphorylation GO:0018105 101 0.063
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.062
embryonic organ development GO:0048568 36 0.062
proteasomal protein catabolic process GO:0010498 176 0.062
regulation of purine nucleotide catabolic process GO:0033121 205 0.061
regulation of peptide transport GO:0090087 62 0.061
enzyme linked receptor protein signaling pathway GO:0007167 303 0.060
cellular response to abiotic stimulus GO:0071214 117 0.060
regulation of axon guidance GO:1902667 3 0.059
positive regulation of transport GO:0051050 336 0.059
response to bacterium GO:0009617 144 0.059
histone ubiquitination GO:0016574 31 0.059
intracellular receptor signaling pathway GO:0030522 104 0.058
regulation of endothelial cell migration GO:0010594 67 0.058
defense response to other organism GO:0098542 129 0.057
pallium development GO:0021543 10 0.057
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.057
blood vessel development GO:0001568 172 0.057
negative regulation of programmed cell death GO:0043069 321 0.057
growth GO:0040007 202 0.055
reproductive process GO:0022414 106 0.055
cytokinesis GO:0000910 96 0.055
negative regulation of phosphate metabolic process GO:0045936 267 0.055
histone monoubiquitination GO:0010390 20 0.054
regulation of epithelial cell proliferation GO:0050678 113 0.054
cellular component morphogenesis GO:0032989 314 0.054
cilium assembly GO:0042384 63 0.054
positive regulation of kinase activity GO:0033674 204 0.054
double strand break repair via homologous recombination GO:0000724 50 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.052
epithelial cell proliferation GO:0050673 128 0.052
cellular amino acid metabolic process GO:0006520 116 0.051
lung growth GO:0060437 2 0.051
cell projection organization GO:0030030 252 0.051
posttranscriptional regulation of gene expression GO:0010608 213 0.051
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.051
regulation of angiogenesis GO:0045765 92 0.050
histone demethylation GO:0016577 15 0.050
regulation of protein transport GO:0051223 213 0.050
peptide transport GO:0015833 74 0.050
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.049
nucleoside triphosphate catabolic process GO:0009143 394 0.048
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.048
reciprocal dna recombination GO:0035825 4 0.048
mitotic dna damage checkpoint GO:0044773 28 0.047
neurological system process GO:0050877 163 0.046
regulation of cellular response to growth factor stimulus GO:0090287 76 0.045
cerebral cortex cell migration GO:0021795 3 0.045
positive regulation of cell migration GO:0030335 172 0.045
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.045
hippocampus development GO:0021766 1 0.044
signal transduction by p53 class mediator GO:0072331 72 0.044
positive regulation of nucleoside metabolic process GO:0045979 186 0.044
regulation of gene expression epigenetic GO:0040029 73 0.044
regulation of anatomical structure morphogenesis GO:0022603 286 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
reciprocal meiotic recombination GO:0007131 4 0.043
positive regulation of protein catabolic process GO:0045732 75 0.043
sensory perception of chemical stimulus GO:0007606 38 0.043
signal transduction in response to dna damage GO:0042770 57 0.042
regulation of mitotic cell cycle GO:0007346 189 0.042
regulation of protein catabolic process GO:0042176 155 0.042
nervous system development GO:0007399 293 0.042
cellular response to hormone stimulus GO:0032870 125 0.041
regulation of actin polymerization or depolymerization GO:0008064 56 0.041
regulation of phospholipase c activating g protein coupled receptor signaling pathway GO:1900736 1 0.041
immune response GO:0006955 307 0.041
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.041
gtp catabolic process GO:0006184 237 0.040
cell division GO:0051301 168 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
negative regulation of chromosome organization GO:2001251 48 0.040
regulation of cell cycle process GO:0010564 266 0.040
negative regulation of intracellular signal transduction GO:1902532 183 0.040
negative regulation of protein metabolic process GO:0051248 391 0.039
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.039
microtubule based movement GO:0007018 32 0.039
regulation of vasculature development GO:1901342 97 0.039
regulation of camp mediated signaling GO:0043949 13 0.039
wnt signaling pathway GO:0016055 156 0.038
cilium morphogenesis GO:0060271 75 0.038
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
membrane organization GO:0061024 292 0.038
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.038
recombinational repair GO:0000725 50 0.038
cellular response to radiation GO:0071478 65 0.037
smoothened signaling pathway GO:0007224 14 0.037
protein k48 linked ubiquitination GO:0070936 38 0.037
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.037
positive regulation of actin filament polymerization GO:0030838 38 0.037
system process GO:0003008 349 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.036
regulation of mitochondrion organization GO:0010821 54 0.036
memory GO:0007613 3 0.036
regulation of signal transduction by p53 class mediator GO:1901796 26 0.036
maintenance of protein location in cell GO:0032507 56 0.036
regulation of locomotion GO:0040012 329 0.035
negative regulation of histone modification GO:0031057 19 0.035
translesion synthesis GO:0019985 8 0.034
cellular response to organic cyclic compound GO:0071407 127 0.034
amide transport GO:0042886 76 0.034
negative regulation of kinase activity GO:0033673 106 0.033
respiratory tube development GO:0030323 20 0.033
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.033
response to oxygen containing compound GO:1901700 369 0.032
negative regulation of transport GO:0051051 176 0.032
lung alveolus development GO:0048286 4 0.032
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
response to abiotic stimulus GO:0009628 336 0.032
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
chordate embryonic development GO:0043009 34 0.031
cell part morphogenesis GO:0032990 137 0.031
innate immune response GO:0045087 178 0.031
regulation of cellular response to stress GO:0080135 244 0.031
negative regulation of epithelial cell proliferation GO:0050680 48 0.031
histone lysine demethylation GO:0070076 14 0.030
maintenance of protein location GO:0045185 57 0.030
neutrophil degranulation GO:0043312 3 0.030
regulation of cell projection assembly GO:0060491 47 0.030
regulation of meiotic cell cycle GO:0051445 4 0.030
positive regulation of proteolysis GO:0045862 142 0.029
ossification GO:0001503 121 0.029
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.029
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.029
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.029
regulation of keratinocyte proliferation GO:0010837 11 0.029
regulation of cell cycle g1 s phase transition GO:1902806 42 0.028
cell cycle phase transition GO:0044770 173 0.028
regulation of histone modification GO:0031056 47 0.028
positive regulation of gtpase activity GO:0043547 166 0.028
regulation of chromatin modification GO:1903308 51 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
negative regulation of transferase activity GO:0051348 124 0.028
protein oligomerization GO:0051259 173 0.027
secretion by cell GO:0032940 226 0.027
regulation of epithelial cell migration GO:0010632 93 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.027
covalent chromatin modification GO:0016569 254 0.026
peptide metabolic process GO:0006518 51 0.026
regulation of mapk cascade GO:0043408 262 0.026
developmental growth GO:0048589 48 0.026
divalent inorganic cation transport GO:0072511 158 0.026
nuclear import GO:0051170 106 0.025
neurogenesis GO:0022008 169 0.025
peptidyl serine modification GO:0018209 106 0.025
tube morphogenesis GO:0035239 95 0.025
compound eye development GO:0048749 1 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
positive regulation of cytoplasmic transport GO:1903651 82 0.024
actin polymerization or depolymerization GO:0008154 56 0.024
golgi organization GO:0007030 38 0.024
dna repair GO:0006281 198 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
response to misfolded protein GO:0051788 5 0.024
single organism membrane organization GO:0044802 268 0.024
protein demethylation GO:0006482 17 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
positive regulation of tor signaling GO:0032008 11 0.024
oogenesis GO:0048477 2 0.024
inner ear morphogenesis GO:0042472 4 0.024
peptidyl threonine modification GO:0018210 45 0.023
keratinocyte proliferation GO:0043616 17 0.023
protein localization to organelle GO:0033365 280 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
regulation of clathrin mediated endocytosis GO:2000369 4 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
regulation of synaptic plasticity GO:0048167 3 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.022
sequestering of calcium ion GO:0051208 17 0.022
photoreceptor cell differentiation GO:0046530 2 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
protein import GO:0017038 130 0.022
sensory perception of sound GO:0007605 37 0.022
bone mineralization GO:0030282 34 0.022
regulation of chemotaxis GO:0050920 74 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
Mouse
angiogenesis GO:0001525 147 0.021
protein processing GO:0016485 226 0.021
cellular response to organonitrogen compound GO:0071417 124 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
dephosphorylation GO:0016311 209 0.021
single organism cellular localization GO:1902580 332 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
maintenance of location GO:0051235 112 0.021
stem cell division GO:0017145 2 0.021
g1 s transition of mitotic cell cycle GO:0000082 78 0.020
cellular response to lipid GO:0071396 127 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.020
cellular component assembly involved in morphogenesis GO:0010927 73 0.020
positive regulation of jnk cascade GO:0046330 52 0.020
actin filament based process GO:0030029 224 0.020
retinal ganglion cell axon guidance GO:0031290 2 0.020
regulation of synaptic vesicle transport GO:1902803 3 0.020
dna biosynthetic process GO:0071897 40 0.019
renal system development GO:0072001 63 0.019
activation of protein kinase activity GO:0032147 90 0.019
sensory organ development GO:0007423 52 0.019
organelle assembly GO:0070925 176 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
sensory perception GO:0007600 103 0.019
telomere maintenance GO:0000723 32 0.019
regulation of protein targeting GO:1903533 91 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.018
respiratory system development GO:0060541 22 0.018
immune system development GO:0002520 195 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
synapse assembly GO:0007416 8 0.018
regulation of mitochondrial membrane permeability GO:0046902 25 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.018
anterior posterior axis specification GO:0009948 2 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
dna templated transcription termination GO:0006353 3 0.018
response to nitrogen compound GO:1901698 184 0.018
negative regulation of cell cycle GO:0045786 193 0.017
peptidyl threonine phosphorylation GO:0018107 41 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
regulation of intracellular transport GO:0032386 195 0.017
embryonic placenta development GO:0001892 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.017
actin filament organization GO:0007015 128 0.017
somitogenesis GO:0001756 2 0.017
regulation of protein localization GO:0032880 296 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
glycerolipid biosynthetic process GO:0045017 51 0.016
tissue remodeling GO:0048771 16 0.016
regulation of growth GO:0040008 165 0.016
negative regulation of proteolysis GO:0045861 132 0.016
regulation of cell projection organization GO:0031344 107 0.016
nitrogen compound transport GO:0071705 191 0.016
histone modification GO:0016570 251 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
negative regulation of gene expression epigenetic GO:0045814 19 0.016
gene silencing GO:0016458 49 0.016
mitotic spindle organization GO:0007052 27 0.016
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.016
cell cell adhesion mediated by cadherin GO:0044331 4 0.016
negative regulation of developmental process GO:0051093 247 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
negative regulation of protein import into nucleus GO:0042308 30 0.016
cytokine secretion GO:0050663 64 0.016
epithelial cell migration GO:0010631 119 0.016
regulation of cellular component movement GO:0051270 334 0.016
cell substrate adhesion GO:0031589 132 0.015
antimicrobial humoral response GO:0019730 26 0.015
cellular amide metabolic process GO:0043603 69 0.015
lung morphogenesis GO:0060425 6 0.015
positive regulation of cell projection organization GO:0031346 64 0.015
regulation of interleukin 8 secretion GO:2000482 13 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
epithelial tube morphogenesis GO:0060562 38 0.015
negative regulation of chromatin modification GO:1903309 21 0.015
anatomical structure homeostasis GO:0060249 100 0.015
negative regulation of smoothened signaling pathway GO:0045879 3 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
regulation of rab protein signal transduction GO:0032483 39 0.015
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.015
sterol transport GO:0015918 39 0.015
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
mitotic recombination GO:0006312 8 0.014
eye development GO:0001654 42 0.014
response to transforming growth factor beta GO:0071559 94 0.014
response to fibroblast growth factor GO:0071774 39 0.014
transcription factor import into nucleus GO:0042991 40 0.014
positive regulation of meiosis i GO:0060903 1 0.014
vesicle organization GO:0016050 62 0.014
microtubule anchoring GO:0034453 24 0.014
receptor mediated endocytosis GO:0006898 84 0.014
negative regulation of cellular amide metabolic process GO:0034249 3 0.014
methylation GO:0032259 106 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
multicellular organism reproduction GO:0032504 42 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
cell projection morphogenesis GO:0048858 129 0.014
regulation of protein import into nucleus GO:0042306 78 0.014
regulation of cell shape GO:0008360 48 0.014
positive regulation of intracellular protein transport GO:0090316 76 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.013
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.013
regulation of fibroblast proliferation GO:0048145 32 0.013
positive regulation of dna recombination GO:0045911 3 0.013
microtubule organizing center organization GO:0031023 62 0.013
response to hypoxia GO:0001666 96 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.013
regulation of protein tyrosine kinase activity GO:0061097 36 0.013
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 20 0.013
regulation of interleukin 8 production GO:0032677 49 0.013
response to radiation GO:0009314 151 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
regulation of protein processing GO:0070613 150 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
epithelium migration GO:0090132 119 0.013

UBR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.205
developmental disorder of mental health DOID:0060037 29 0.205
specific developmental disorder DOID:0060038 19 0.205
intellectual disability DOID:1059 13 0.205
cardiovascular system disease DOID:1287 106 0.057
muscular disease DOID:0080000 114 0.049
musculoskeletal system disease DOID:17 223 0.049
myopathy DOID:423 104 0.025
heart disease DOID:114 68 0.025
cardiomyopathy DOID:0050700 50 0.025
dilated cardiomyopathy DOID:12930 32 0.025
intrinsic cardiomyopathy DOID:0060036 50 0.025
muscle tissue disease DOID:66 113 0.025
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014