Homo sapiens

138 known processes

SGSM2

small G protein signaling modulator 2

(Aliases: KIAA0397,RUTBC1)

SGSM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 63 0.888
cilium morphogenesis GO:0060271 75 0.849
tissue morphogenesis GO:0048729 96 0.503
epithelium development GO:0060429 227 0.477
anatomical structure formation involved in morphogenesis GO:0048646 284 0.426
morphogenesis of embryonic epithelium GO:0016331 4 0.382
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.353
cellular component morphogenesis GO:0032989 314 0.206
neural tube formation GO:0001841 3 0.204
establishment of tissue polarity GO:0007164 3 0.175
cellular amine metabolic process GO:0044106 41 0.166
embryonic epithelial tube formation GO:0001838 4 0.165
histone modification GO:0016570 251 0.157
morphogenesis of an epithelium GO:0002009 60 0.137
cell projection assembly GO:0030031 126 0.134
cellular component assembly involved in morphogenesis GO:0010927 73 0.130
regulation of cellular component biogenesis GO:0044087 281 0.119
cell part morphogenesis GO:0032990 137 0.111
small gtpase mediated signal transduction GO:0007264 78 0.108
cell projection organization GO:0030030 252 0.108
ras protein signal transduction GO:0007265 73 0.104
covalent chromatin modification GO:0016569 254 0.101
regulation of protein localization GO:0032880 296 0.099
taxis GO:0042330 157 0.099
iron ion homeostasis GO:0055072 15 0.097
wnt signaling pathway GO:0016055 156 0.095
biological adhesion GO:0022610 331 0.094
organ morphogenesis GO:0009887 147 0.093
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.091
chromatin organization GO:0006325 351 0.090
blastoderm segmentation GO:0007350 2 0.089
enzyme linked receptor protein signaling pathway GO:0007167 303 0.088
amine metabolic process GO:0009308 44 0.085
regulation of cellular amino acid metabolic process GO:0006521 6 0.085
cell projection morphogenesis GO:0048858 129 0.081
regulation of cell morphogenesis GO:0022604 153 0.081
regulation of anatomical structure morphogenesis GO:0022603 286 0.080
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.079
regulation of cellular amine metabolic process GO:0033238 11 0.076
g protein coupled receptor signaling pathway GO:0007186 207 0.075
transition metal ion homeostasis GO:0055076 31 0.074
cation homeostasis GO:0055080 189 0.073
primary neural tube formation GO:0014020 3 0.070
hindbrain development GO:0030902 3 0.070
segmentation GO:0035282 4 0.069
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.066
regulation of cell projection organization GO:0031344 107 0.066
spinal cord development GO:0021510 4 0.064
bmp signaling pathway GO:0030509 49 0.064
determination of adult lifespan GO:0008340 2 0.064
neuron projection development GO:0031175 106 0.063
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.063
cell morphogenesis GO:0000902 296 0.063
microtubule based process GO:0007017 210 0.062
cellular lipid metabolic process GO:0044255 303 0.062
regulation of neuron differentiation GO:0045664 70 0.061
regulation of cell migration GO:0030334 289 0.060
neural tube closure GO:0001843 3 0.058
cell morphogenesis involved in differentiation GO:0000904 144 0.058
regulation of cell differentiation GO:0045595 393 0.058
purine ribonucleotide catabolic process GO:0009154 404 0.057
cilium organization GO:0044782 68 0.056
positive regulation of nucleoside metabolic process GO:0045979 186 0.054
chromatin modification GO:0016568 298 0.053
organic anion transport GO:0015711 103 0.053
cellular ketone metabolic process GO:0042180 80 0.052
regulation of nucleoside metabolic process GO:0009118 209 0.050
head development GO:0060322 108 0.049
metal ion homeostasis GO:0055065 169 0.048
chemical homeostasis GO:0048878 306 0.047
regulation of neurogenesis GO:0050767 82 0.047
cell adhesion GO:0007155 325 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.045
nucleotide catabolic process GO:0009166 408 0.045
positive regulation of cellular component organization GO:0051130 376 0.045
cell development GO:0048468 328 0.045
neuromuscular junction development GO:0007528 3 0.043
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.043
carbohydrate derivative biosynthetic process GO:1901137 207 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.039
protein acylation GO:0043543 138 0.039
cellular response to dna damage stimulus GO:0006974 379 0.038
regulation of nervous system development GO:0051960 88 0.038
regulation of cell motility GO:2000145 299 0.038
embryonic morphogenesis GO:0048598 85 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
central nervous system development GO:0007417 123 0.037
urea metabolic process GO:0019627 3 0.037
transmembrane transport GO:0055085 399 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
neurogenesis GO:0022008 169 0.036
histone acetylation GO:0016573 93 0.036
nervous system development GO:0007399 293 0.036
tube morphogenesis GO:0035239 95 0.036
cellular protein complex assembly GO:0043623 188 0.036
glycosyl compound catabolic process GO:1901658 413 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.035
regulation of protein kinase activity GO:0045859 289 0.034
negative regulation of cellular component movement GO:0051271 106 0.033
regulation of cell cycle process GO:0010564 266 0.033
regulation of axon guidance GO:1902667 3 0.033
axon cargo transport GO:0008088 2 0.033
calcium ion transmembrane transport GO:0070588 76 0.032
notch signaling pathway GO:0007219 31 0.032
gtp catabolic process GO:0006184 237 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
cell fate determination GO:0001709 3 0.032
regulation of bmp signaling pathway GO:0030510 27 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
carbohydrate metabolic process GO:0005975 207 0.031
microtubule cytoskeleton organization GO:0000226 176 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
metencephalon development GO:0022037 2 0.030
negative regulation of developmental process GO:0051093 247 0.030
negative regulation of programmed cell death GO:0043069 321 0.029
negative regulation of intracellular signal transduction GO:1902532 183 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.029
positive regulation of catabolic process GO:0009896 310 0.029
nitrogen compound transport GO:0071705 191 0.029
norepinephrine transport GO:0015874 1 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
regeneration GO:0031099 4 0.028
cation transport GO:0006812 331 0.028
actin filament based process GO:0030029 224 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
embryo development GO:0009790 123 0.028
regulation of neuron projection development GO:0010975 57 0.027
anion transport GO:0006820 161 0.027
single organism membrane organization GO:0044802 268 0.027
endosomal transport GO:0016197 129 0.027
regulation of cell development GO:0060284 161 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
regulation of locomotion GO:0040012 329 0.026
organophosphate catabolic process GO:0046434 430 0.026
regulation of transferase activity GO:0051338 355 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
catecholamine secretion GO:0050432 1 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
innate immune response GO:0045087 178 0.025
secretion GO:0046903 254 0.025
cell cell adhesion GO:0098609 19 0.025
endomembrane system organization GO:0010256 196 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
organelle assembly GO:0070925 176 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
neuron development GO:0048666 113 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
regulation of protein serine threonine kinase activity GO:0071900 179 0.024
neural tube development GO:0021915 9 0.024
intracellular protein transport GO:0006886 270 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.023
multicellular organismal aging GO:0010259 3 0.023
regulation of axonogenesis GO:0050770 16 0.023
generation of neurons GO:0048699 152 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
post embryonic development GO:0009791 2 0.023
neuron differentiation GO:0030182 138 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
response to external biotic stimulus GO:0043207 261 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
negative regulation of epithelial cell proliferation GO:0050680 48 0.022
glycoprotein metabolic process GO:0009100 110 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
cation transmembrane transport GO:0098655 238 0.021
protein localization to organelle GO:0033365 280 0.021
cerebellum development GO:0021549 2 0.021
organelle fission GO:0048285 149 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
negative regulation of protein modification process GO:0031400 200 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
metal ion transport GO:0030001 272 0.021
peptidyl lysine acetylation GO:0018394 101 0.021
histone deacetylation GO:0016575 32 0.020
neuron projection morphogenesis GO:0048812 50 0.020
female gamete generation GO:0007292 2 0.020
response to oxygen containing compound GO:1901700 369 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
regulation of cellular component movement GO:0051270 334 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
associative learning GO:0008306 1 0.020
vesicle mediated transport GO:0016192 371 0.020
regulation of establishment of planar polarity GO:0090175 5 0.020
positive regulation of dendrite morphogenesis GO:0050775 3 0.020
lipid metabolic process GO:0006629 381 0.020
dephosphorylation GO:0016311 209 0.019
positive regulation of transcription during mitosis GO:0045897 2 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
cell cell signaling GO:0007267 155 0.019
regulation of synapse assembly GO:0051963 5 0.019
negative regulation of cell migration GO:0030336 102 0.019
regulation of dna metabolic process GO:0051052 153 0.019
macromolecule deacylation GO:0098732 41 0.019
glycerolipid metabolic process GO:0046486 107 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of protein catabolic process GO:0042176 155 0.019
negative regulation of cell death GO:0060548 345 0.018
macromolecule glycosylation GO:0043413 63 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
positive regulation of digestive system process GO:0060456 2 0.018
organic hydroxy compound transport GO:0015850 63 0.018
brain development GO:0007420 97 0.018
negative regulation of binding GO:0051100 57 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
axis elongation GO:0003401 4 0.018
memory GO:0007613 3 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
regulation of rab gtpase activity GO:0032313 39 0.017
limbic system development GO:0021761 3 0.017
secretion by cell GO:0032940 226 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
negative regulation of notch signaling pathway GO:0045746 10 0.017
peptide secretion GO:0002790 51 0.017
purine containing compound catabolic process GO:0072523 411 0.017
negative regulation of transport GO:0051051 176 0.017
regulation of transcription during mitosis GO:0045896 2 0.017
visual behavior GO:0007632 2 0.017
neurological system process GO:0050877 163 0.017
glycosylation GO:0070085 71 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
axon development GO:0061564 34 0.016
defense response GO:0006952 315 0.016
bicarbonate transport GO:0015701 6 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
cellular amino acid metabolic process GO:0006520 116 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
cell matrix adhesion GO:0007160 85 0.016
mapk cascade GO:0000165 288 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
growth GO:0040007 202 0.016
mitotic nuclear division GO:0007067 119 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
immune response GO:0006955 307 0.016
glycoprotein biosynthetic process GO:0009101 91 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
protein methylation GO:0006479 74 0.016
internal peptidyl lysine acetylation GO:0018393 97 0.016
positive regulation of transport GO:0051050 336 0.016
regulation of cell division GO:0051302 116 0.016
peptidyl lysine modification GO:0018205 144 0.016
microtubule organizing center organization GO:0031023 62 0.015
positive regulation of kinase activity GO:0033674 204 0.015
nuclear division GO:0000280 128 0.015
protein deacylation GO:0035601 39 0.015
negative regulation of organelle organization GO:0010639 126 0.015
calcium ion transport GO:0006816 147 0.015
nucleoside catabolic process GO:0009164 408 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
phospholipid metabolic process GO:0006644 99 0.015
protein catabolic process GO:0030163 325 0.015
regulation of rab protein signal transduction GO:0032483 39 0.015
convergent extension GO:0060026 1 0.015
positive regulation of rab gtpase activity GO:0032851 39 0.015
regulation of transmembrane transport GO:0034762 139 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
histone methylation GO:0016571 60 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
regulation of cellular response to stress GO:0080135 244 0.014
actin mediated cell contraction GO:0070252 12 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
positive regulation of transferase activity GO:0051347 227 0.014
negative regulation of phosphatase activity GO:0010923 61 0.014
regulation of kinase activity GO:0043549 314 0.014
centrosome organization GO:0051297 58 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
regulation of proteolysis GO:0030162 293 0.014
neuroblast proliferation GO:0007405 4 0.014
methylation GO:0032259 106 0.014
regionalization GO:0003002 29 0.014
protein alkylation GO:0008213 74 0.014
chemotaxis GO:0006935 157 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
response to oxidative stress GO:0006979 121 0.014
neuron projection guidance GO:0097485 12 0.014
ameboidal type cell migration GO:0001667 135 0.014
cytoplasmic transport GO:0016482 379 0.014
protein glycosylation GO:0006486 62 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
interspecies interaction between organisms GO:0044419 156 0.014
negative regulation of cell motility GO:2000146 104 0.014
rna interference GO:0016246 4 0.013
hormone transport GO:0009914 68 0.013
positive regulation of defense response GO:0031349 87 0.013
positive regulation of immune system process GO:0002684 283 0.013
divalent metal ion transport GO:0070838 152 0.013
regulation of mapk cascade GO:0043408 262 0.013
motor neuron axon guidance GO:0008045 2 0.013
protein deacetylation GO:0006476 38 0.013
synapse organization GO:0050808 14 0.013
oogenesis GO:0048477 2 0.013
dendrite development GO:0016358 24 0.013
glycerolipid biosynthetic process GO:0045017 51 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
apoptotic signaling pathway GO:0097190 268 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
regulation of epithelial cell migration GO:0010632 93 0.013
regulation of notch signaling pathway GO:0008593 18 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
lung cell differentiation GO:0060479 1 0.013
behavior GO:0007610 112 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
negative regulation of catabolic process GO:0009895 104 0.013
positive regulation of cell death GO:0010942 263 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
protein ubiquitination GO:0016567 314 0.012
regulation of endothelial cell migration GO:0010594 67 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
rab protein signal transduction GO:0032482 4 0.012
regulation of axon extension involved in axon guidance GO:0048841 2 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
peptide transport GO:0015833 74 0.012
cell type specific apoptotic process GO:0097285 125 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
regulation of binding GO:0051098 111 0.012
visual learning GO:0008542 1 0.012
protein localization to membrane GO:0072657 160 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
regulation of protein transport GO:0051223 213 0.012
startle response GO:0001964 3 0.012
compound eye development GO:0048749 1 0.012
epithelial cell proliferation GO:0050673 128 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
macromolecule methylation GO:0043414 97 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
neuron projection regeneration GO:0031102 1 0.012
pancreatic juice secretion GO:0030157 4 0.012
mitochondrion organization GO:0007005 156 0.012
regulation of endothelial cell proliferation GO:0001936 56 0.012
establishment of planar polarity GO:0001736 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
meiotic chromosome segregation GO:0045132 4 0.011
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.011
skeletal system development GO:0001501 79 0.011
actin cytoskeleton organization GO:0030036 207 0.011
response to organic cyclic compound GO:0014070 204 0.011
positive regulation of organelle organization GO:0010638 195 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
establishment of nucleus localization GO:0040023 1 0.011
glucose metabolic process GO:0006006 45 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
blood vessel morphogenesis GO:0048514 162 0.011
system process GO:0003008 349 0.011
regulation of gtpase activity GO:0043087 180 0.011
glycerophospholipid metabolic process GO:0006650 84 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
regulation of cell growth GO:0001558 135 0.011
protein acetylation GO:0006473 116 0.011
hippocampus development GO:0021766 1 0.011
regulation of immune response GO:0050776 201 0.011
regulation of transcription involved in cell fate commitment GO:0060850 6 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
melanin metabolic process GO:0006582 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
actin filament based movement GO:0030048 17 0.011
locomotory behavior GO:0007626 1 0.011
defense response to other organism GO:0098542 129 0.011
regulation of secretion by cell GO:1903530 177 0.011
lipid biosynthetic process GO:0008610 177 0.010
single organism cellular localization GO:1902580 332 0.010
synapse assembly GO:0007416 8 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
peptide hormone secretion GO:0030072 50 0.010
myosin filament assembly GO:0031034 2 0.010
regulation of intracellular transport GO:0032386 195 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
response to axon injury GO:0048678 1 0.010
protein oligomerization GO:0051259 173 0.010
mitotic cell cycle GO:0000278 326 0.010
regulation of multi organism process GO:0043900 157 0.010
cell substrate adhesion GO:0031589 132 0.010
neuron migration GO:0001764 11 0.010
regulation of phosphatase activity GO:0010921 81 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
activation of protein kinase activity GO:0032147 90 0.010
circadian behavior GO:0048512 2 0.010

SGSM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.057
nervous system disease DOID:863 431 0.057
disease of metabolism DOID:0014667 295 0.021
inherited metabolic disorder DOID:655 242 0.021
musculoskeletal system disease DOID:17 223 0.015
brain disease DOID:936 73 0.015
myopathy DOID:423 104 0.014
muscular disease DOID:0080000 114 0.014
muscular dystrophy DOID:9884 51 0.014
muscle tissue disease DOID:66 113 0.014