Homo sapiens

12 known processes

CDC25C

cell division cycle 25 homolog C (S. pombe)

(Aliases: CDC25)

CDC25C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 393 0.954
Human Worm Fly
cell cycle g2 m phase transition GO:0044839 43 0.841
mitotic cell cycle process GO:1903047 286 0.728
mitotic cell cycle GO:0000278 326 0.663
regulation of mitotic cell cycle GO:0007346 189 0.630
Human Worm Fly
g2 m transition of mitotic cell cycle GO:0000086 41 0.619
nuclear division GO:0000280 128 0.611
Worm Fly
regulation of cell cycle process GO:0010564 266 0.523
Human
cellular response to dna damage stimulus GO:0006974 379 0.473
organelle fission GO:0048285 149 0.469
Worm Fly
cell division GO:0051301 168 0.467
Human Worm
mitotic cell cycle phase transition GO:0044772 162 0.440
oocyte differentiation GO:0009994 2 0.430
negative regulation of cell cycle GO:0045786 193 0.365
Worm Fly
male meiosis GO:0007140 1 0.355
Fly
spindle assembly GO:0051225 29 0.347
Fly
dephosphorylation GO:0016311 209 0.312
Fly
regulation of kinase activity GO:0043549 314 0.293
regulation of protein serine threonine kinase activity GO:0071900 179 0.292
mitotic cell cycle checkpoint GO:0007093 68 0.271
negative regulation of phosphate metabolic process GO:0045936 267 0.255
cell cycle phase transition GO:0044770 173 0.253
oocyte maturation GO:0001556 1 0.247
positive regulation of protein phosphorylation GO:0001934 313 0.247
mitotic nuclear division GO:0007067 119 0.223
microtubule based process GO:0007017 210 0.211
Worm Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.195
ubiquitin dependent protein catabolic process GO:0006511 206 0.189
post embryonic development GO:0009791 2 0.187
Worm
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.187
positive regulation of protein kinase activity GO:0045860 190 0.183
dna repair GO:0006281 198 0.182
female gamete generation GO:0007292 2 0.179
regulation of cell cycle phase transition GO:1901987 126 0.178
oocyte development GO:0048599 1 0.178
cell cycle checkpoint GO:0000075 117 0.162
chromosome segregation GO:0007059 114 0.157
regulation of cellular ketone metabolic process GO:0010565 50 0.146
centrosome separation GO:0051299 3 0.145
peptidyl serine phosphorylation GO:0018105 101 0.136
regulation of cell division GO:0051302 116 0.135
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.135
sister chromatid segregation GO:0000819 54 0.134
regulation of protein kinase activity GO:0045859 289 0.132
negative regulation of protein metabolic process GO:0051248 391 0.131
negative regulation of mitotic cell cycle GO:0045930 102 0.128
Worm Fly
cellular response to endogenous stimulus GO:0071495 336 0.126
g2 dna damage checkpoint GO:0031572 26 0.122
response to radiation GO:0009314 151 0.120
Human
cellular protein catabolic process GO:0044257 261 0.116
cell development GO:0048468 328 0.115
Fly
negative regulation of phosphorylation GO:0042326 174 0.115
mitotic sister chromatid segregation GO:0000070 53 0.113
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.113
dna damage checkpoint GO:0000077 68 0.112
negative regulation of cellular protein metabolic process GO:0032269 353 0.111
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.108
response to uv GO:0009411 73 0.104
Human
positive regulation of phosphorylation GO:0042327 394 0.102
centrosome cycle GO:0007098 32 0.102
Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.094
response to abiotic stimulus GO:0009628 336 0.092
Human
positive regulation of organelle organization GO:0010638 195 0.091
regulation of meiotic cell cycle GO:0051445 4 0.091
Worm Fly
histone threonine phosphorylation GO:0035405 7 0.088
organelle assembly GO:0070925 176 0.087
Fly
meiosis i GO:0007127 4 0.087
centrosome organization GO:0051297 58 0.087
Fly
cellular component disassembly GO:0022411 92 0.085
Fly
microtubule organizing center organization GO:0031023 62 0.083
Fly
cell cycle g1 s phase transition GO:0044843 80 0.083
regulation of transferase activity GO:0051338 355 0.082
positive regulation of cell cycle GO:0045787 140 0.081
Human Worm Fly
oogenesis GO:0048477 2 0.081
sister chromatid cohesion GO:0007062 24 0.080
regulation of cellular amine metabolic process GO:0033238 11 0.080
regulation of microtubule based process GO:0032886 74 0.079
negative regulation of protein phosphorylation GO:0001933 140 0.079
dna integrity checkpoint GO:0031570 71 0.078
meiotic nuclear division GO:0007126 10 0.073
Worm Fly
regulation of nuclear division GO:0051783 65 0.069
spindle organization GO:0007051 53 0.067
Worm Fly
cellular ketone metabolic process GO:0042180 80 0.067
embryo development GO:0009790 123 0.066
Worm Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
mitotic cytokinesis GO:0000281 19 0.065
regulation of protein dephosphorylation GO:0035304 18 0.065
protein catabolic process GO:0030163 325 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.064
cellular response to abiotic stimulus GO:0071214 117 0.064
Human
peptidyl serine modification GO:0018209 106 0.064
modification dependent macromolecule catabolic process GO:0043632 212 0.063
positive regulation of kinase activity GO:0033674 204 0.061
regulation of dephosphorylation GO:0035303 96 0.061
cellular response to uv GO:0034644 32 0.060
Human
regulation of binding GO:0051098 111 0.059
protein autophosphorylation GO:0046777 123 0.059
regulation of cellular component size GO:0032535 82 0.059
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.058
covalent chromatin modification GO:0016569 254 0.058
peptidyl threonine modification GO:0018210 45 0.058
histone modification GO:0016570 251 0.058
regulation of cardiac muscle tissue growth GO:0055021 4 0.057
negative regulation of cell cycle process GO:0010948 121 0.057
positive regulation of cellular component organization GO:0051130 376 0.054
protein dephosphorylation GO:0006470 81 0.052
Fly
histone serine phosphorylation GO:0035404 4 0.052
amine metabolic process GO:0009308 44 0.052
membrane organization GO:0061024 292 0.051
Fly
dna replication GO:0006260 116 0.051
positive regulation of cell division GO:0051781 59 0.051
Human
golgi disassembly GO:0090166 2 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
activation of protein kinase activity GO:0032147 90 0.050
regulation of microtubule cytoskeleton organization GO:0070507 61 0.049
meiotic chromosome segregation GO:0045132 4 0.049
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.047
epithelium development GO:0060429 227 0.046
immune response GO:0006955 307 0.046
protein maturation GO:0051604 233 0.046
regulation of protein maturation GO:1903317 150 0.046
peptidyl threonine phosphorylation GO:0018107 41 0.044
regulation of mitosis GO:0007088 63 0.044
nervous system development GO:0007399 293 0.043
microtubule polymerization or depolymerization GO:0031109 37 0.042
positive regulation of cell cycle process GO:0090068 106 0.042
Human
negative regulation of cell size GO:0045792 3 0.042
Fly
positive regulation of mitosis GO:0045840 25 0.042
ras protein signal transduction GO:0007265 73 0.042
protein processing GO:0016485 226 0.041
mitotic dna damage checkpoint GO:0044773 28 0.041
g1 s transition of mitotic cell cycle GO:0000082 78 0.041
negative regulation of dephosphorylation GO:0035305 63 0.040
mitotic spindle organization GO:0007052 27 0.040
cellular amine metabolic process GO:0044106 41 0.039
cellular amino acid metabolic process GO:0006520 116 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
modification dependent protein catabolic process GO:0019941 209 0.038
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.037
negative regulation of protein maturation GO:1903318 142 0.036
cytokinesis GO:0000910 96 0.036
Human
positive regulation of exit from mitosis GO:0031536 2 0.035
maintenance of location GO:0051235 112 0.035
spindle checkpoint GO:0031577 26 0.035
positive regulation of hydrolase activity GO:0051345 331 0.034
rna processing GO:0006396 255 0.034
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.034
negative regulation of protein modification process GO:0031400 200 0.034
regulation of cytokinesis GO:0032465 45 0.033
Human
positive regulation of developmental process GO:0051094 314 0.033
Fly
negative regulation of cellular component organization GO:0051129 235 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
anatomical structure homeostasis GO:0060249 100 0.033
apoptotic signaling pathway GO:0097190 268 0.033
signal transduction by phosphorylation GO:0023014 297 0.032
regulation of cytoskeleton organization GO:0051493 177 0.032
centrosome duplication GO:0051298 28 0.032
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.032
positive regulation of catabolic process GO:0009896 310 0.031
positive regulation of transferase activity GO:0051347 227 0.031
histone acetylation GO:0016573 93 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.030
regulation of chromosome segregation GO:0051983 44 0.030
posttranscriptional regulation of gene expression GO:0010608 213 0.030
negative regulation of protein processing GO:0010955 142 0.030
response to organonitrogen compound GO:0010243 156 0.030
regulation of proteolysis GO:0030162 293 0.030
regulation of protein stability GO:0031647 87 0.030
regulation of protein binding GO:0043393 66 0.029
negative regulation of organelle organization GO:0010639 126 0.029
tube development GO:0035295 125 0.029
Fly
protein ubiquitination GO:0016567 314 0.028
negative regulation of kinase activity GO:0033673 106 0.028
microtubule cytoskeleton organization GO:0000226 176 0.027
Worm Fly
neuroblast proliferation GO:0007405 4 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
chromatin organization GO:0006325 351 0.027
regulation of cell differentiation GO:0045595 393 0.027
negative regulation of cell proliferation GO:0008285 228 0.026
spindle midzone assembly GO:0051255 4 0.026
positive regulation of cytokinesis GO:0032467 29 0.026
Human
proteasomal protein catabolic process GO:0010498 176 0.026
mitotic sister chromatid separation GO:0051306 18 0.025
regulation of phosphatase activity GO:0010921 81 0.025
regulation of peptidase activity GO:0052547 180 0.024
dna biosynthetic process GO:0071897 40 0.024
peptidyl tyrosine dephosphorylation GO:0035335 36 0.024
Fly
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.024
negative regulation of protein kinase activity GO:0006469 98 0.024
reproductive process GO:0022414 106 0.024
Fly
single organism membrane organization GO:0044802 268 0.024
Fly
regulation of cysteine type endopeptidase activity GO:2000116 127 0.023
protein homooligomerization GO:0051260 100 0.023
chromatin modification GO:0016568 298 0.023
mrna processing GO:0006397 133 0.023
mapk cascade GO:0000165 288 0.023
protein acylation GO:0043543 138 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.022
regulation of protein localization GO:0032880 296 0.022
regulation of chromosome organization GO:0033044 103 0.022
reactive oxygen species metabolic process GO:0072593 75 0.022
double strand break repair GO:0006302 101 0.022
negative regulation of transferase activity GO:0051348 124 0.022
organophosphate catabolic process GO:0046434 430 0.021
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.021
multicellular organismal aging GO:0010259 3 0.021
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.021
regulation of protein catabolic process GO:0042176 155 0.021
negative regulation of mitosis GO:0045839 24 0.021
regulation of neuroblast proliferation GO:1902692 3 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
regulation of sister chromatid cohesion GO:0007063 9 0.020
cellular response to light stimulus GO:0071482 34 0.020
Human
negative regulation of apoptotic process GO:0043066 316 0.020
determination of adult lifespan GO:0008340 2 0.020
eye photoreceptor cell differentiation GO:0001754 2 0.020
protein acetylation GO:0006473 116 0.020
regulation of dna replication GO:0006275 68 0.020
neuromuscular junction development GO:0007528 3 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
negative regulation of protein dephosphorylation GO:0035308 3 0.020
positive regulation of chromosome organization GO:2001252 41 0.020
reproduction GO:0000003 63 0.020
Worm Fly
organelle inheritance GO:0048308 2 0.020
cell growth GO:0016049 160 0.020
negative regulation of binding GO:0051100 57 0.019
regulation of cellular response to stress GO:0080135 244 0.019
dna catabolic process exonucleolytic GO:0000738 17 0.019
regulation of mitotic sister chromatid segregation GO:0033047 27 0.019
cellular homeostasis GO:0019725 196 0.019
circulatory system development GO:0072359 262 0.019
response to oxygen containing compound GO:1901700 369 0.019
single organism reproductive process GO:0044702 98 0.019
Fly
regulation of cell diameter GO:0060305 1 0.019
Fly
g protein coupled receptor signaling pathway GO:0007186 207 0.018
meiotic cell cycle GO:0051321 13 0.018
Worm Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.018
dna catabolic process GO:0006308 49 0.018
regulation of anatomical structure size GO:0090066 101 0.018
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.018
actomyosin contractile ring organization GO:0044837 1 0.018
immune system development GO:0002520 195 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
epithelial cell proliferation GO:0050673 128 0.018
protein localization to organelle GO:0033365 280 0.018
spermatid differentiation GO:0048515 4 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
negative regulation of cell death GO:0060548 345 0.017
regulation of vasculature development GO:1901342 97 0.017
peptidyl lysine acetylation GO:0018394 101 0.017
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
positive regulation of proteolysis GO:0045862 142 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
negative regulation of transport GO:0051051 176 0.016
response to hypoxia GO:0001666 96 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
peptidyl lysine modification GO:0018205 144 0.016
regulation of cell motility GO:2000145 299 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
spermatid development GO:0007286 4 0.016
tissue regeneration GO:0042246 3 0.016
negative regulation of proteolysis GO:0045861 132 0.015
microtubule bundle formation GO:0001578 15 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
immune effector process GO:0002252 159 0.015
nucleotide catabolic process GO:0009166 408 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
cellular protein complex assembly GO:0043623 188 0.015
positive regulation of protein catabolic process GO:0045732 75 0.015
microtubule nucleation GO:0007020 6 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of protein complex assembly GO:0043254 147 0.015
defense response GO:0006952 315 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
developmental process involved in reproduction GO:0003006 66 0.015
Fly
protein targeting GO:0006605 187 0.015
metaphase plate congression GO:0051310 18 0.015
cell part morphogenesis GO:0032990 137 0.015
mitotic dna replication checkpoint GO:0033314 2 0.015
response to organic cyclic compound GO:0014070 204 0.015
regulation of centrosome cycle GO:0046605 15 0.014
blood vessel morphogenesis GO:0048514 162 0.014
cellular component morphogenesis GO:0032989 314 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
Human Fly
negative regulation of hydrolase activity GO:0051346 182 0.014
regulation of mapk cascade GO:0043408 262 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
regulation of intracellular transport GO:0032386 195 0.014
response to acid chemical GO:0001101 66 0.014
regulation of chromatin modification GO:1903308 51 0.014
protein polymerization GO:0051258 71 0.013
regulation of cellular component movement GO:0051270 334 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
response to lipid GO:0033993 206 0.013
positive regulation of chromosome segregation GO:0051984 9 0.013
telomere maintenance GO:0000723 32 0.013
regulation of histone modification GO:0031056 47 0.013
regulation of dna repair GO:0006282 47 0.013
regulation of cell cycle g2 m phase transition GO:1902749 22 0.013
generation of neurons GO:0048699 152 0.013
neurogenesis GO:0022008 169 0.013
growth GO:0040007 202 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
nucleus organization GO:0006997 28 0.013
Fly
maintenance of protein location in cell GO:0032507 56 0.013
cell cycle arrest GO:0007050 71 0.013
cell morphogenesis GO:0000902 296 0.013
positive regulation of map kinase activity GO:0043406 80 0.013
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.013
positive regulation of immune system process GO:0002684 283 0.013
regulation of protein processing GO:0070613 150 0.013
response to toxic substance GO:0009636 37 0.013
mitotic spindle elongation GO:0000022 4 0.013
mitotic dna integrity checkpoint GO:0044774 30 0.012
histone phosphorylation GO:0016572 16 0.012
response to wounding GO:0009611 168 0.012
response to nitrogen compound GO:1901698 184 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
neuroblast division GO:0055057 1 0.012
cell activation GO:0001775 213 0.012
microtubule anchoring GO:0034453 24 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
negative regulation of phosphatase activity GO:0010923 61 0.012
maintenance of location in cell GO:0051651 62 0.012
regulation of cell cycle g1 s phase transition GO:1902806 42 0.012
negative regulation of chromosome organization GO:2001251 48 0.012
tube morphogenesis GO:0035239 95 0.012
Fly
positive regulation of ligase activity GO:0051351 19 0.012
neuron differentiation GO:0030182 138 0.012
metaphase anaphase transition of cell cycle GO:0044784 21 0.012
cardiovascular system development GO:0072358 262 0.012
signal transduction in response to dna damage GO:0042770 57 0.012
response to light stimulus GO:0009416 87 0.012
Human
regulation of spindle organization GO:0090224 10 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.011
regulation of homeostatic process GO:0032844 121 0.011
protein destabilization GO:0031648 12 0.011
regulation of angiogenesis GO:0045765 92 0.011
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.011
positive regulation of protein transport GO:0051222 135 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
respiratory tube development GO:0030323 20 0.011
dna double strand break processing GO:0000729 10 0.011
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.011
response to antibiotic GO:0046677 15 0.011
non recombinational repair GO:0000726 14 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.011
spindle elongation GO:0051231 4 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
negative regulation of catalytic activity GO:0043086 335 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
positive regulation of dephosphorylation GO:0035306 26 0.010
centriole replication GO:0007099 13 0.010
Fly
cell type specific apoptotic process GO:0097285 125 0.010
gland development GO:0048732 48 0.010

CDC25C disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.016
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012
thoracic cancer DOID:5093 21 0.010