Homo sapiens

448 known processes

SNCA

synuclein, alpha (non A4 component of amyloid precursor)

(Aliases: MGC110988,NACP,PARK1,PD1,PARK4)

SNCA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neurotransmitter secretion GO:0046928 3 0.932
Mouse
secretion GO:0046903 254 0.906
secretion by cell GO:0032940 226 0.840
regulation of cellular component biogenesis GO:0044087 281 0.549
cation transport GO:0006812 331 0.531
serotonin transport GO:0006837 3 0.526
regulation of neurotransmitter levels GO:0001505 15 0.506
serotonin uptake GO:0051610 2 0.501
regulation of cell development GO:0060284 161 0.440
amine metabolic process GO:0009308 44 0.437
nucleoside catabolic process GO:0009164 408 0.431
regulation of neurotransmitter transport GO:0051588 7 0.428
glycine import GO:0036233 1 0.409
negative regulation of protein metabolic process GO:0051248 391 0.401
locomotory behavior GO:0007626 1 0.395
Mouse
neurotransmitter secretion GO:0007269 4 0.393
Mouse
positive regulation of catabolic process GO:0009896 310 0.390
regulation of locomotion GO:0040012 329 0.378
Mouse
cell development GO:0048468 328 0.355
positive regulation of cellular component organization GO:0051130 376 0.333
nucleoside triphosphate metabolic process GO:0009141 422 0.316
Mouse
glycine transport GO:0015816 3 0.313
nucleoside phosphate catabolic process GO:1901292 412 0.299
regulation of proteolysis GO:0030162 293 0.298
regulation of purine nucleotide metabolic process GO:1900542 264 0.290
positive regulation of programmed cell death GO:0043068 249 0.279
cell cell signaling GO:0007267 155 0.278
response to oxygen containing compound GO:1901700 369 0.271
somatic stem cell division GO:0048103 1 0.270
asymmetric neuroblast division GO:0055059 1 0.266
response to abiotic stimulus GO:0009628 336 0.264
nervous system development GO:0007399 293 0.263
stem cell division GO:0017145 2 0.256
regulation of peroxidase activity GO:2000468 2 0.256
ribonucleotide catabolic process GO:0009261 405 0.254
neuroblast division GO:0055057 1 0.252
multicellular organismal aging GO:0010259 3 0.241
cellular response to oxygen containing compound GO:1901701 276 0.234
negative regulation of apoptotic process GO:0043066 316 0.234
vesicle mediated transport GO:0016192 371 0.229
positive regulation of developmental process GO:0051094 314 0.228
organic hydroxy compound transport GO:0015850 63 0.226
signal release GO:0023061 70 0.225
Mouse
regulation of secretion GO:0051046 194 0.225
purine nucleoside triphosphate catabolic process GO:0009146 392 0.224
hemopoiesis GO:0030097 180 0.224
purine containing compound catabolic process GO:0072523 411 0.222
adult locomotory behavior GO:0008344 1 0.222
Mouse
monoamine transport GO:0015844 10 0.217
regulation of cellular amine metabolic process GO:0033238 11 0.215
ras protein signal transduction GO:0007265 73 0.214
cell morphogenesis GO:0000902 296 0.212
cellular amino acid metabolic process GO:0006520 116 0.211
purine containing compound biosynthetic process GO:0072522 88 0.204
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.201
Mouse
positive regulation of apoptotic process GO:0043065 246 0.197
transmembrane transport GO:0055085 399 0.195
cyclic nucleotide biosynthetic process GO:0009190 61 0.194
organophosphate catabolic process GO:0046434 430 0.194
ion homeostasis GO:0050801 230 0.193
regulation of cellular amino acid metabolic process GO:0006521 6 0.190
single organism cellular localization GO:1902580 332 0.189
negative regulation of protein processing GO:0010955 142 0.184
purine ribonucleoside catabolic process GO:0046130 398 0.183
regulation of secretion by cell GO:1903530 177 0.179
growth GO:0040007 202 0.175
microtubule based process GO:0007017 210 0.175
membrane organization GO:0061024 292 0.174
Mouse
carboxylic acid transport GO:0046942 63 0.171
Mouse
associative learning GO:0008306 1 0.169
glycosyl compound catabolic process GO:1901658 413 0.166
nucleoside phosphate biosynthetic process GO:1901293 109 0.164
negative regulation of transport GO:0051051 176 0.163
response to cytokine GO:0034097 232 0.162
cellular response to monoamine stimulus GO:0071868 7 0.157
positive regulation of gtpase activity GO:0043547 166 0.156
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.155
cyclic purine nucleotide metabolic process GO:0052652 60 0.153
cell growth GO:0016049 160 0.153
regulation of microtubule polymerization GO:0031113 12 0.152
purine nucleotide catabolic process GO:0006195 405 0.151
purine ribonucleotide catabolic process GO:0009154 404 0.150
asymmetric stem cell division GO:0098722 1 0.150
apoptotic signaling pathway GO:0097190 268 0.149
positive regulation of cellular amine metabolic process GO:0033240 7 0.148
visual learning GO:0008542 1 0.147
negative regulation of programmed cell death GO:0043069 321 0.143
positive regulation of nucleotide catabolic process GO:0030813 185 0.142
camp biosynthetic process GO:0006171 47 0.142
single organism membrane organization GO:0044802 268 0.141
Mouse
peptidyl serine modification GO:0018209 106 0.140
Mouse
neurogenesis GO:0022008 169 0.139
positive regulation of organelle organization GO:0010638 195 0.138
dopamine transport GO:0015872 5 0.131
negative regulation of cell death GO:0060548 345 0.130
chemical homeostasis GO:0048878 306 0.130
cation transmembrane transport GO:0098655 238 0.129
ribonucleoside catabolic process GO:0042454 406 0.128
axon cargo transport GO:0008088 2 0.127
neuron projection development GO:0031175 106 0.127
positive regulation of cellular catabolic process GO:0031331 284 0.127
purine nucleoside triphosphate metabolic process GO:0009144 412 0.126
Mouse
memory GO:0007613 3 0.126
neurotransmitter transport GO:0006836 10 0.125
gtp catabolic process GO:0006184 237 0.124
amino acid transport GO:0006865 28 0.124
Mouse
regulation of synaptic vesicle exocytosis GO:2000300 2 0.122
positive regulation of axon extension GO:0045773 4 0.121
protein modification by small protein conjugation GO:0032446 342 0.121
nucleoside triphosphate catabolic process GO:0009143 394 0.119
regulation of nucleotide metabolic process GO:0006140 269 0.118
forebrain development GO:0030900 26 0.118
negative regulation of protein maturation GO:1903318 142 0.117
small gtpase mediated signal transduction GO:0007264 78 0.113
neurological system process GO:0050877 163 0.110
positive regulation of immune system process GO:0002684 283 0.105
cellular homeostasis GO:0019725 196 0.105
regulation of purine nucleotide catabolic process GO:0033121 205 0.104
regulation of camp biosynthetic process GO:0030817 45 0.104
synaptic transmission GO:0007268 61 0.104
cellular divalent inorganic cation homeostasis GO:0072503 128 0.104
inclusion body assembly GO:0070841 17 0.103
nucleotide catabolic process GO:0009166 408 0.101
positive regulation of hydrolase activity GO:0051345 331 0.100
cellular calcium ion homeostasis GO:0006874 117 0.099
endocytosis GO:0006897 159 0.098
protein processing GO:0016485 226 0.098
positive regulation of nucleotide metabolic process GO:0045981 230 0.097
post embryonic development GO:0009791 2 0.097
l amino acid import GO:0043092 4 0.096
synaptic vesicle endocytosis GO:0048488 2 0.096
Mouse
purine nucleotide biosynthetic process GO:0006164 84 0.095
protein localization to membrane GO:0072657 160 0.095
positive regulation of cell death GO:0010942 263 0.095
positive regulation of ras gtpase activity GO:0032320 117 0.094
cellular component morphogenesis GO:0032989 314 0.094
positive regulation of cellular component biogenesis GO:0044089 158 0.093
regulation of vesicle mediated transport GO:0060627 130 0.093
regulation of cellular component movement GO:0051270 334 0.092
long term memory GO:0007616 2 0.089
microtubule cytoskeleton organization GO:0000226 176 0.088
protein maturation GO:0051604 233 0.087
cyclic nucleotide metabolic process GO:0009187 82 0.087
ribonucleoside triphosphate metabolic process GO:0009199 412 0.086
Mouse
exocytosis GO:0006887 71 0.085
cellular chemical homeostasis GO:0055082 180 0.085
cell proliferation in forebrain GO:0021846 1 0.085
microtubule polymerization GO:0046785 18 0.083
cellular macromolecular complex assembly GO:0034622 324 0.082
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.082
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.082
regulation of gtp catabolic process GO:0033124 180 0.082
positive regulation of nucleoside metabolic process GO:0045979 186 0.081
cell death in response to oxidative stress GO:0036473 29 0.081
rho protein signal transduction GO:0007266 26 0.081
brain development GO:0007420 97 0.081
positive regulation of transport GO:0051050 336 0.080
amino acid transmembrane transport GO:0003333 20 0.079
positive regulation of protein complex assembly GO:0031334 86 0.079
protein catabolic process GO:0030163 325 0.079
cellular ion homeostasis GO:0006873 168 0.079
negative regulation of cell cycle GO:0045786 193 0.079
organic hydroxy compound metabolic process GO:1901615 147 0.078
regulation of cellular ketone metabolic process GO:0010565 50 0.078
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.077
regulation of cell motility GO:2000145 299 0.077
neuroblast proliferation GO:0007405 4 0.077
response to organonitrogen compound GO:0010243 156 0.076
regulation of camp metabolic process GO:0030814 52 0.076
regulation of cell projection organization GO:0031344 107 0.076
cell morphogenesis involved in differentiation GO:0000904 144 0.076
regulation of endopeptidase activity GO:0052548 170 0.075
purine nucleoside catabolic process GO:0006152 398 0.074
positive regulation of cell differentiation GO:0045597 211 0.074
regulation of inclusion body assembly GO:0090083 13 0.074
regulation of protein processing GO:0070613 150 0.074
camp metabolic process GO:0046058 61 0.073
regulation of small gtpase mediated signal transduction GO:0051056 156 0.073
cellular response to organic cyclic compound GO:0071407 127 0.073
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.072
positive regulation of cell proliferation GO:0008284 301 0.071
regulation of protein complex assembly GO:0043254 147 0.071
determination of adult lifespan GO:0008340 2 0.069
regulation of nucleotide catabolic process GO:0030811 205 0.069
response to radiation GO:0009314 151 0.069
hematopoietic or lymphoid organ development GO:0048534 186 0.069
positive regulation of cell migration GO:0030335 172 0.068
protein targeting GO:0006605 187 0.068
cellular ketone metabolic process GO:0042180 80 0.068
Mouse
cell projection organization GO:0030030 252 0.067
carbohydrate derivative biosynthetic process GO:1901137 207 0.067
gtp metabolic process GO:0046039 239 0.067
regulation of metal ion transport GO:0010959 120 0.067
regulation of mitotic cell cycle GO:0007346 189 0.066
regulation of intracellular transport GO:0032386 195 0.066
nitrogen compound transport GO:0071705 191 0.066
response to nitrogen compound GO:1901698 184 0.066
cellular lipid metabolic process GO:0044255 303 0.066
Mouse
axonogenesis GO:0007409 31 0.066
guanosine containing compound catabolic process GO:1901069 239 0.066
negative regulation of catalytic activity GO:0043086 335 0.066
chemotaxis GO:0006935 157 0.065
regulation of cell cycle GO:0051726 393 0.065
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.064
sodium ion transport GO:0006814 61 0.064
negative regulation of proteolysis GO:0045861 132 0.064
protein localization to organelle GO:0033365 280 0.064
cell projection morphogenesis GO:0048858 129 0.063
neuron development GO:0048666 113 0.062
ribose phosphate biosynthetic process GO:0046390 82 0.061
response to biotic stimulus GO:0009607 276 0.061
regulation of protein transport GO:0051223 213 0.060
regulation of ras protein signal transduction GO:0046578 155 0.060
cell part morphogenesis GO:0032990 137 0.060
immune system development GO:0002520 195 0.060
response to extracellular stimulus GO:0009991 85 0.060
regulation of homeostatic process GO:0032844 121 0.059
regulation of protein polymerization GO:0032271 63 0.059
negative regulation of developmental process GO:0051093 247 0.059
protein ubiquitination GO:0016567 314 0.058
anion transmembrane transport GO:0098656 76 0.057
ribonucleotide biosynthetic process GO:0009260 81 0.057
positive regulation of neurogenesis GO:0050769 49 0.057
neuron differentiation GO:0030182 138 0.056
mitotic cell cycle GO:0000278 326 0.056
negative regulation of cellular component organization GO:0051129 235 0.056
divalent inorganic cation homeostasis GO:0072507 136 0.055
neuromuscular junction development GO:0007528 3 0.055
defense response GO:0006952 315 0.055
female gamete generation GO:0007292 2 0.055
intrinsic apoptotic signaling pathway GO:0097193 127 0.055
generation of neurons GO:0048699 152 0.054
negative regulation of cellular protein metabolic process GO:0032269 353 0.053
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.053
Mouse
cell cycle phase transition GO:0044770 173 0.053
regulation of cell differentiation GO:0045595 393 0.052
negative regulation of hydrolase activity GO:0051346 182 0.052
purine ribonucleoside metabolic process GO:0046128 437 0.052
Mouse
regulation of neuron differentiation GO:0045664 70 0.052
establishment or maintenance of neuroblast polarity GO:0045196 1 0.052
response to metal ion GO:0010038 84 0.051
positive regulation of anoikis GO:2000210 4 0.051
positive regulation of protein phosphorylation GO:0001934 313 0.051
negative regulation of phosphorylation GO:0042326 174 0.051
regulation of protein maturation GO:1903317 150 0.051
positive regulation of leukocyte activation GO:0002696 80 0.051
cell activation GO:0001775 213 0.050
Mouse
negative regulation of secretion GO:0051048 58 0.050
regulation of synaptic plasticity GO:0048167 3 0.049
Mouse
circadian behavior GO:0048512 2 0.049
mitotic cell cycle process GO:1903047 286 0.049
establishment of cell polarity GO:0030010 22 0.049
regulation of protein localization GO:0032880 296 0.048
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.048
inorganic cation transmembrane transport GO:0098662 194 0.048
enzyme linked receptor protein signaling pathway GO:0007167 303 0.048
divalent metal ion transport GO:0070838 152 0.047
response to lithium ion GO:0010226 2 0.047
cell adhesion GO:0007155 325 0.047
immune response GO:0006955 307 0.047
metal ion homeostasis GO:0055065 169 0.047
mitotic cell cycle phase transition GO:0044772 162 0.046
regulation of exocytosis GO:0017157 46 0.046
mating GO:0007618 1 0.046
collateral sprouting GO:0048668 2 0.046
negative regulation of serotonin secretion GO:0014063 1 0.046
cellular macromolecule catabolic process GO:0044265 380 0.046
positive regulation of gtp catabolic process GO:0033126 166 0.045
cytoplasmic transport GO:0016482 379 0.045
translation GO:0006412 132 0.045
purine ribonucleotide biosynthetic process GO:0009152 79 0.045
neuronal stem cell division GO:0036445 1 0.045
response to oxidative stress GO:0006979 121 0.045
regulation of synaptic vesicle transport GO:1902803 3 0.045
organelle localization GO:0051640 84 0.044
Mouse
negative regulation of cell development GO:0010721 48 0.044
positive regulation of cell activation GO:0050867 81 0.044
synaptic transmission glycinergic GO:0060012 1 0.044
cellular response to ammonium ion GO:0071242 4 0.044
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.044
regulation of synaptic transmission dopaminergic GO:0032225 4 0.044
cellular metal ion homeostasis GO:0006875 146 0.043
single organism carbohydrate metabolic process GO:0044723 193 0.043
endosomal transport GO:0016197 129 0.043
regulation of neuroblast proliferation GO:1902692 3 0.043
regulation of anatomical structure size GO:0090066 101 0.043
regulation of gtpase activity GO:0043087 180 0.042
regulation of kidney size GO:0035564 2 0.042
regulation of response to oxidative stress GO:1902882 26 0.042
regulation of cell cycle process GO:0010564 266 0.042
rhythmic behavior GO:0007622 2 0.042
amino acid import GO:0043090 4 0.042
regulation of autophagy GO:0010506 52 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
calcium ion homeostasis GO:0055074 122 0.042
negative regulation of ion transport GO:0043271 39 0.041
negative regulation of protein modification process GO:0031400 200 0.041
response to organic cyclic compound GO:0014070 204 0.041
regulation of establishment of protein localization GO:0070201 242 0.041
regulation of dendritic cell apoptotic process GO:2000668 4 0.041
sequestering of calcium ion GO:0051208 17 0.040
regulation of cell migration GO:0030334 289 0.040
negative regulation of protein transport GO:0051224 75 0.040
positive regulation of proteolysis GO:0045862 142 0.040
positive regulation of rho gtpase activity GO:0032321 56 0.039
angiogenesis GO:0001525 147 0.039
regulation of growth GO:0040008 165 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
regulation of peptidyl serine phosphorylation GO:0033135 50 0.039
Mouse
taxis GO:0042330 157 0.039
proline transport GO:0015824 4 0.039
regulation of ion transport GO:0043269 189 0.039
protein localization to nucleus GO:0034504 136 0.038
positive regulation of immune response GO:0050778 159 0.038
mitochondrion localization GO:0051646 10 0.038
negative regulation of intracellular transport GO:0032387 60 0.038
protein import into nucleus GO:0006606 104 0.038
negative regulation of jun kinase activity GO:0043508 4 0.038
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.038
Mouse
establishment of organelle localization GO:0051656 59 0.037
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.037
regulation of nucleoside metabolic process GO:0009118 209 0.037
response to wounding GO:0009611 168 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.035
establishment or maintenance of cell polarity GO:0007163 31 0.035
cation homeostasis GO:0055080 189 0.035
system process GO:0003008 349 0.035
regulation of rho gtpase activity GO:0032319 66 0.035
response to lipid GO:0033993 206 0.035
response to catecholamine GO:0071869 7 0.034
regulation of reactive oxygen species metabolic process GO:2000377 41 0.034
mitochondrion transport along microtubule GO:0047497 3 0.034
regulation of binding GO:0051098 111 0.034
innate immune response GO:0045087 178 0.034
head development GO:0060322 108 0.034
protein secretion GO:0009306 98 0.034
organophosphate biosynthetic process GO:0090407 163 0.034
regulation of cellular response to stress GO:0080135 244 0.034
negative regulation of cd8 positive alpha beta t cell activation GO:2001186 1 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.034
positive regulation of cell development GO:0010720 92 0.034
lymphocyte activation GO:0046649 133 0.034
peripheral nervous system development GO:0007422 2 0.034
regulation of endocytosis GO:0030100 72 0.033
response to nutrient levels GO:0031667 81 0.033
regulation of cellular protein catabolic process GO:1903362 96 0.033
regulation of calcium ion transport GO:0051924 79 0.033
response to hydrogen peroxide GO:0042542 40 0.033
thalamus development GO:0021794 2 0.033
regulation of microtubule cytoskeleton organization GO:0070507 61 0.033
regulation of synaptic transmission GO:0050804 11 0.033
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.033
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.032
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.032
dopamine receptor signaling pathway GO:0007212 10 0.032
circadian sleep wake cycle process GO:0022410 2 0.032
leukocyte activation GO:0045321 164 0.032
Mouse
modification dependent protein catabolic process GO:0019941 209 0.032
cell division GO:0051301 168 0.031
regulation of cell activation GO:0050865 125 0.031
Mouse
response to endoplasmic reticulum stress GO:0034976 49 0.031
negative regulation of peptidase activity GO:0010466 91 0.031
cytokine mediated signaling pathway GO:0019221 109 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
autophagy GO:0006914 88 0.031
metal ion transport GO:0030001 272 0.030
l amino acid transport GO:0015807 14 0.030
single organism membrane fusion GO:0044801 37 0.030
organic acid transport GO:0015849 65 0.030
Mouse
response to axon injury GO:0048678 1 0.030
regulation of synaptic vesicle endocytosis GO:1900242 1 0.030
regulation of synaptic vesicle recycling GO:1903421 1 0.030
sequestering of metal ion GO:0051238 24 0.030
cellular response to nitrogen compound GO:1901699 144 0.030
nucleocytoplasmic transport GO:0006913 176 0.030
endomembrane system organization GO:0010256 196 0.030
posttranscriptional regulation of gene expression GO:0010608 213 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.030
guanosine containing compound metabolic process GO:1901068 244 0.029
neuron neuron synaptic transmission GO:0007270 6 0.029
cellular response to dna damage stimulus GO:0006974 379 0.029
response to molecule of bacterial origin GO:0002237 82 0.029
nuclear transport GO:0051169 179 0.029
serotonin secretion GO:0001820 1 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
regulation of cellular response to oxidative stress GO:1900407 26 0.029
positive regulation of cellular component movement GO:0051272 181 0.028
oogenesis GO:0048477 2 0.028
positive regulation of cell motility GO:2000147 177 0.028
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.028
ion transmembrane transport GO:0034220 338 0.028
proteasomal protein catabolic process GO:0010498 176 0.028
cellular response to catecholamine stimulus GO:0071870 7 0.028
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.028
regulation of neurogenesis GO:0050767 82 0.028
anion transport GO:0006820 161 0.028
Mouse
regulation of meiotic cell cycle GO:0051445 4 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.028
cellular response to organonitrogen compound GO:0071417 124 0.028
protein homooligomerization GO:0051260 100 0.027
positive regulation of protein polymerization GO:0032273 45 0.027
regulation of immune response GO:0050776 201 0.027
regulation of mitochondrion organization GO:0010821 54 0.027
aging GO:0007568 66 0.027
positive regulation of cell projection organization GO:0031346 64 0.027
negative regulation of endopeptidase activity GO:0010951 84 0.027
positive regulation of secretion GO:0051047 116 0.027
Mouse
regulation of neural precursor cell proliferation GO:2000177 4 0.027
response to hormone GO:0009725 175 0.026
common partner smad protein phosphorylation GO:0007182 3 0.026
protein oligomerization GO:0051259 173 0.026
establishment of protein localization to organelle GO:0072594 172 0.026
metencephalon development GO:0022037 2 0.026
peptidyl serine phosphorylation GO:0018105 101 0.026
Mouse
catecholamine transport GO:0051937 6 0.026
mapk cascade GO:0000165 288 0.026
regulation of oxidoreductase activity GO:0051341 43 0.026
regulation of lymphocyte activation GO:0051249 103 0.026
axon development GO:0061564 34 0.026
regulation of protein secretion GO:0050708 86 0.026
cytokine production GO:0001816 247 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.026
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.025
synaptic vesicle exocytosis GO:0016079 3 0.025
regulation of kinase activity GO:0043549 314 0.025
chromatin organization GO:0006325 351 0.025
behavior GO:0007610 112 0.025
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
central nervous system development GO:0007417 123 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
transition metal ion homeostasis GO:0055076 31 0.025
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 3 0.025
organic anion transport GO:0015711 103 0.025
Mouse
regulation of cell growth GO:0001558 135 0.025
apoptotic mitochondrial changes GO:0008637 57 0.025
cellular protein complex assembly GO:0043623 188 0.025
g protein coupled receptor signaling pathway GO:0007186 207 0.025
retrograde transport endosome to golgi GO:0042147 45 0.025
hindbrain development GO:0030902 3 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.024
response to steroid hormone GO:0048545 80 0.024
regulation of cell morphogenesis GO:0022604 153 0.024
regulation of nervous system development GO:0051960 88 0.024
protein targeting to nucleus GO:0044744 104 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
regulation of protein kinase activity GO:0045859 289 0.024
regulation of t cell activation GO:0050863 77 0.024
positive regulation of neuron projection development GO:0010976 34 0.024
regulation of leukocyte activation GO:0002694 115 0.024
Mouse
dendritic spine morphogenesis GO:0060997 3 0.024
protein localization to plasma membrane GO:0072659 93 0.024
cytoskeleton dependent intracellular transport GO:0030705 21 0.024
regulation of cytokine production GO:0001817 232 0.024
negative regulation of secretion by cell GO:1903531 52 0.024
response to mechanical stimulus GO:0009612 51 0.023
extrinsic apoptotic signaling pathway GO:0097191 119 0.023
regulation of interleukin 10 secretion GO:2001179 4 0.023
osteoclast development GO:0036035 2 0.023
regeneration GO:0031099 4 0.023
cellular protein catabolic process GO:0044257 261 0.023
autophagic cell death GO:0048102 3 0.023
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.023
positive regulation of lymphocyte activation GO:0051251 73 0.023
stem cell proliferation GO:0072089 25 0.023
maintenance of location GO:0051235 112 0.023
nucleotide biosynthetic process GO:0009165 109 0.022
stress activated mapk cascade GO:0051403 93 0.022
positive regulation of cytoskeleton organization GO:0051495 83 0.022
morphogenesis of a polarized epithelium GO:0001738 3 0.022
positive regulation of cell cycle process GO:0090068 106 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.022
negative regulation of neuron differentiation GO:0045665 21 0.022

SNCA disease predictions

Disease DO term ID Size Probability Func Analog Org
parkinson s disease DOID:14330 18 0.661
synucleinopathy DOID:0050890 22 0.661
central nervous system disease DOID:331 186 0.661
neurodegenerative disease DOID:1289 102 0.661
nervous system disease DOID:863 431 0.661
disease of mental health DOID:150 70 0.359
substance related disorder DOID:303 10 0.115
brain disease DOID:936 73 0.092
disease of metabolism DOID:0014667 295 0.076
acquired metabolic disease DOID:0060158 58 0.043
cognitive disorder DOID:1561 29 0.042
muscular disease DOID:0080000 114 0.036
musculoskeletal system disease DOID:17 223 0.036
tauopathy DOID:680 16 0.029
cancer DOID:162 167 0.028
disease of cellular proliferation DOID:14566 174 0.028
muscle tissue disease DOID:66 113 0.027
myopathy DOID:423 104 0.026
organ system cancer DOID:0050686 164 0.025