|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.396
|
|
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
0.386
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.364
|
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.355
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.335
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.334
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.324
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.304
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.303
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.293
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.291
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.290
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.278
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.278
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.278
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.273
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.272
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.271
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.263
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.256
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.255
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.251
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.247
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.237
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.233
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.225
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.224
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.216
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.207
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.205
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.199
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.190
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.190
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.190
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.188
|
|
|
|
regulation of cgmp mediated signaling
|
GO:0010752 |
1 |
0.188
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.187
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.185
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.184
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.182
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.177
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.176
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.175
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.175
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.173
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.173
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.171
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.170
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.166
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.162
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.161
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.160
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.160
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.157
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.157
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.156
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.155
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.150
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.150
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.149
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.149
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.148
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.147
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.144
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.144
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.143
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.143
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.142
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.140
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.140
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.140
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.136
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.135
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.134
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.134
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.132
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.132
|
|
|
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.132
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.131
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.130
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.130
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.129
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.129
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.128
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.128
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.125
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.124
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.124
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.123
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.123
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.121
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.119
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.116
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.116
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.116
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.116
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.115
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.114
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.114
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.113
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.111
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.111
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.110
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.110
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.109
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.108
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.108
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.108
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.108
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.107
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.106
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.105
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.104
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.104
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.103
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.103
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.102
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.101
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.101
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.101
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.101
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.100
|
Human |
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.099
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.098
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.098
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.098
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.097
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.097
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.097
|
Human |
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.097
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.096
|
Human |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.096
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.096
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.095
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.093
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.092
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.092
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.091
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.091
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.089
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.089
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.087
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.087
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.086
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.086
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.086
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.085
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.085
|
|
|
|
system process
|
GO:0003008 |
349 |
0.085
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.084
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.084
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.084
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.082
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.081
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
16 |
0.081
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.081
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.080
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.079
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.079
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.078
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.078
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.078
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.077
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.077
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.077
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.076
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.076
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.075
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.074
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.073
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.073
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.073
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.073
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.073
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.072
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.071
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.071
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.071
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.071
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.070
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.070
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.070
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.070
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.069
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.069
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.069
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.069
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.068
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.068
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.067
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.067
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.067
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.066
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.066
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.065
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.064
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.064
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.064
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.063
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.063
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.063
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.063
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.063
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.063
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.063
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.062
|
|
|
|
negative regulation of bone mineralization
|
GO:0030502 |
7 |
0.062
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.061
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.061
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.061
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.060
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.060
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.060
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.059
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.059
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.059
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.058
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.057
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.057
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.057
|
Human |
|
|
immune effector process
|
GO:0002252 |
159 |
0.056
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.056
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.056
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.056
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.055
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.055
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.055
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.055
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.055
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.054
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.053
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.053
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.053
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.053
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.053
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.053
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
26 |
0.052
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.052
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.052
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.052
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.052
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.052
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.051
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.051
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.051
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.051
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.051
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.051
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.050
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.049
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.049
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.049
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.049
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
2 |
0.049
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.049
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.048
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.048
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.047
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.047
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.047
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.046
|
|
|
|
polyol metabolic process
|
GO:0019751 |
32 |
0.046
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.046
|
Human |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.046
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.046
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.046
|
|
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.046
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.046
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.045
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.045
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.045
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.045
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.045
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.045
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.045
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.044
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.044
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.044
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.043
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.043
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.043
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.043
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.042
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.042
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.042
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.042
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.042
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.042
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.042
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.042
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.041
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.041
|
|
|
|
negative regulation of biomineral tissue development
|
GO:0070168 |
8 |
0.041
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.041
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.040
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.040
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.040
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.040
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.040
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.040
|
|
|
|
memory
|
GO:0007613 |
3 |
0.040
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.040
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.040
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.040
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.040
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.040
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.040
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.039
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.039
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.039
|
|
|
|
translation
|
GO:0006412 |
132 |
0.039
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.039
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.039
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.038
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.038
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.038
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.038
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.038
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.038
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.038
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.038
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.038
|
Human |
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.037
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.037
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.037
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.037
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.037
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.037
|
Human |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.037
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.036
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.036
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.036
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.036
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.036
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.036
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.035
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.035
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.035
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.035
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.035
|
Human |
|
|
anion transport
|
GO:0006820 |
161 |
0.034
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.034
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.034
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.034
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.034
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.034
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.033
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.033
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.033
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.033
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.033
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.033
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.033
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.032
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.032
|
|
|
|
growth
|
GO:0040007 |
202 |
0.032
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.032
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.032
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.032
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.031
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.031
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.031
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.031
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.031
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.031
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.031
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.031
|
|
|
|
mating
|
GO:0007618 |
1 |
0.031
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.031
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.031
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.030
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.030
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.030
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.030
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.030
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.030
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
6 |
0.030
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.030
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.030
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.030
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.030
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.030
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.030
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.030
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.030
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.030
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.029
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.029
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.029
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.029
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.029
|
Human |
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.029
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.029
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.029
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.029
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.028
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.028
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.028
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.028
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.028
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.028
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.027
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.027
|
Human |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.027
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.027
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.027
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.027
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.027
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.027
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.027
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.027
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.027
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.027
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.026
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.026
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.026
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.026
|
|
|
|
regulation of inositol trisphosphate biosynthetic process
|
GO:0032960 |
1 |
0.026
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.026
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.026
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.026
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.026
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.025
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.025
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.025
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.025
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.025
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.025
|
|
|
|
cgmp mediated signaling
|
GO:0019934 |
5 |
0.025
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.025
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.024
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.024
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.024
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.024
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.024
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.024
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.024
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.024
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.024
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.024
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.024
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.024
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.024
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.023
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.023
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.023
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.023
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.023
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.023
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.023
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.023
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.023
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.023
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.023
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.023
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.023
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.022
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.022
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.022
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.022
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.022
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
22 |
0.022
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.022
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.022
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.021
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.021
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.021
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.021
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.021
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.021
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.021
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.021
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.021
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.021
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.021
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.021
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.021
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.021
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.021
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.021
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.021
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.021
|
|
