|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.467
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.452
|
Human Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.418
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.395
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
99 |
0.381
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.352
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.289
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.248
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.229
|
Rat |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.228
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.227
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.200
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.196
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.191
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.185
|
Mouse |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.182
|
Yeast Rat |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.178
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.174
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.169
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.167
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.167
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.162
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.159
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.157
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.156
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.156
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.154
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.152
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.150
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.149
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.137
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.136
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.134
|
Human |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.133
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.132
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.132
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.132
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.127
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.121
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.117
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.117
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.114
|
Rat |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.109
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.109
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.109
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.109
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.103
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.099
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.097
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.096
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.096
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.091
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.091
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.091
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.090
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.090
|
Human |
|
|
cellular defense response
|
GO:0006968 |
2 |
0.089
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.089
|
Human Rat |
|
|
cell activation
|
GO:0001775 |
213 |
0.089
|
Human Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.089
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.088
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.087
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.087
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.087
|
Mouse |
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.086
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.086
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.086
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.086
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.086
|
Rat |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.085
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.084
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.084
|
Human Rat |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.083
|
Human Rat |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.081
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.080
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.078
|
Rat |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.078
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.078
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.076
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.076
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.075
|
Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.075
|
Human |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.074
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.072
|
Human Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.071
|
Rat |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.071
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.071
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.070
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.070
|
Yeast |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.069
|
Human Rat |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.069
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.069
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.068
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.067
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.067
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.067
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.066
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.065
|
Human Rat |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.065
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.064
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.064
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.063
|
Rat |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.063
|
Mouse |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.063
|
Human Rat |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.063
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.062
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.062
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.062
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.061
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.061
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.060
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.059
|
Rat |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.059
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.059
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.059
|
Human |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.058
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.058
|
Human |
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.058
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.058
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.058
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.057
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.057
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.057
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.057
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.056
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.056
|
Human Rat |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.056
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.055
|
Rat |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.055
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.055
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.055
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.054
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.054
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.053
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.053
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.052
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.052
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.051
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.050
|
Human Rat |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.050
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.050
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.049
|
Human |
|
|
regulation of icosanoid secretion
|
GO:0032303 |
4 |
0.049
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.049
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.049
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.049
|
Rat |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.049
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.048
|
Human |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.048
|
|
|
|
system process
|
GO:0003008 |
349 |
0.048
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.048
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.048
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.047
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.047
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.047
|
Yeast |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.047
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.047
|
Human Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.047
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.047
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.046
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.046
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.046
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.046
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.045
|
Rat |
|
|
anion transport
|
GO:0006820 |
161 |
0.045
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.045
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.044
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.044
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.044
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.044
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.044
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.043
|
Human |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.043
|
Human |
|
|
positive thymic t cell selection
|
GO:0045059 |
1 |
0.043
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.043
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.043
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.043
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.043
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.041
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.041
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.041
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.041
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.040
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.040
|
Human |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.040
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.040
|
Rat |
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.040
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.039
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.039
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.039
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.039
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.039
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.039
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.039
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.039
|
Human Rat |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.038
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.038
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.038
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.038
|
Human Rat |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.037
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.037
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.037
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.037
|
Human Rat |
|
|
cation transport
|
GO:0006812 |
331 |
0.037
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.037
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.037
|
Human |
|
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.036
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.036
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.036
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.036
|
Rat |
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.035
|
Human |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.035
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.035
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.035
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.035
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.035
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.035
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.035
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.035
|
Human Rat |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.035
|
Human Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.035
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.035
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.034
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.034
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.034
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.034
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.034
|
Rat |
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.034
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.034
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.034
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.034
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.034
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.033
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.033
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.033
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.033
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.033
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.033
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.033
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.033
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.032
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.032
|
Human |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.032
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.032
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.032
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.031
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.031
|
Rat |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.031
|
Human Rat |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.031
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.031
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.031
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.031
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.031
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.031
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.031
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.031
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.031
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.031
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.031
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.031
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.031
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.031
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.030
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.030
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.030
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.030
|
Rat |
|
|
taxis
|
GO:0042330 |
157 |
0.030
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.030
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.030
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.030
|
Human Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.030
|
Rat |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.030
|
Mouse |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.029
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.029
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.029
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.029
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.029
|
Human |
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
3 |
0.029
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.029
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.028
|
Human |
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.028
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.028
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.028
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.028
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.028
|
Human |
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.028
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.027
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.027
|
Human |
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.027
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.027
|
Rat |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.027
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.027
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.027
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.027
|
Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.027
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.027
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.027
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.027
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.027
|
Rat |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.027
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.027
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.027
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.027
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.027
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.027
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.027
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.027
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.026
|
Human |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.026
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.026
|
Human |
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.026
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.026
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.026
|
Human |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.026
|
Human |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.026
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.026
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.026
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.026
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.026
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.026
|
Human |
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.026
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.026
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.026
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.026
|
Worm |
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.026
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.026
|
|
|
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.025
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.025
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.025
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.025
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.025
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.025
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.025
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.025
|
Mouse |
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.025
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.025
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.025
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.025
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.025
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.025
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.025
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.024
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.024
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.024
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.024
|
Worm |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.024
|
Human Rat |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.024
|
Human Rat |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.024
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.024
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.024
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.024
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.024
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.024
|
Human |
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.024
|
|
|
|
mating
|
GO:0007618 |
1 |
0.024
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.023
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.023
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.023
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.023
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.023
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.023
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.023
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.023
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.023
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.023
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.023
|
Mouse |
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.023
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
1 |
0.023
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.023
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.023
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.023
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.023
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.023
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.023
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.023
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.023
|
Human |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.022
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.022
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.022
|
Mouse |
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.022
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.022
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.022
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.022
|
Human |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.022
|
Rat |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.022
|
Human |
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.022
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.022
|
|
|
|
growth
|
GO:0040007 |
202 |
0.022
|
Human Rat |
|
|
heart contraction
|
GO:0060047 |
62 |
0.022
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.022
|
Human |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.022
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.022
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.022
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.022
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.021
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.021
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.021
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.021
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.021
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.021
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.021
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.021
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.021
|
Human |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.021
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.021
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.021
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.021
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.021
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.021
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.021
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.021
|
Human |
|
|
isotype switching
|
GO:0045190 |
3 |
0.021
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.021
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.020
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.020
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.020
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.020
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.020
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.020
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.020
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.020
|
Human Rat |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.020
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.020
|
Mouse Rat |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.020
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.020
|
Mouse |
|
|
tissue migration
|
GO:0090130 |
119 |
0.020
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.020
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.020
|
Mouse |
|
|
positive regulation of cell migration involved in sprouting angiogenesis
|
GO:0090050 |
3 |
0.020
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.020
|
Human |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.020
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.020
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.020
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.020
|
Human Rat |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.020
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.020
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.020
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.020
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.019
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.019
|
Human Rat |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.019
|
Rat |
|
|
translation
|
GO:0006412 |
132 |
0.019
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.019
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.019
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.019
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.019
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.019
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.019
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.019
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.019
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.019
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.019
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.019
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.019
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.019
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.019
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.019
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.019
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.019
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.019
|
Human Rat |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.019
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.019
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.019
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.018
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.018
|
Human Rat |
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.018
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.018
|
Rat |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.018
|
Human |
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.018
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.018
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.018
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.018
|
Rat |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.018
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.018
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.018
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.018
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.018
|
Human |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.018
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.018
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.018
|
|
