|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.998
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.977
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.973
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.960
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.923
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.825
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.729
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.716
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.716
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.692
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.589
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.568
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.517
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.506
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.471
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.398
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.395
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.389
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.387
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.344
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.343
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.337
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.306
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.292
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.290
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.278
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.265
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.250
|
Mouse Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.245
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.244
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.241
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.238
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.235
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.216
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.215
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.215
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.209
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.206
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.201
|
Human |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.200
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.195
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.192
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.187
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.187
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.175
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.168
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.167
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.167
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.165
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.164
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.163
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.157
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.155
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.152
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.151
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.150
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.150
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.143
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.143
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.139
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.138
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.137
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.134
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.134
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.131
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.129
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.125
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.121
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.119
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.116
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.114
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.114
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.113
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.109
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.108
|
Human |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.108
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.107
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.106
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.106
|
Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.106
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.105
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.102
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.101
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.099
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.099
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.096
|
|
|
|
memory
|
GO:0007613 |
3 |
0.096
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.095
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.095
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.094
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.092
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.090
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.090
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.089
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.088
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.087
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.086
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.084
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.083
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.083
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.082
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.081
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.080
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.078
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.077
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.077
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.075
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.073
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.072
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.070
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.070
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.070
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.069
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.069
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.068
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.068
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.067
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.067
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.066
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.066
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.066
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.066
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.064
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.064
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.063
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.063
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.063
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.062
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.062
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.062
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.060
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.060
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.058
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.057
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.056
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.056
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.056
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.054
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.053
|
Fly |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.052
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.052
|
Mouse |
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.051
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.051
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.049
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.049
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.048
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.048
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.048
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.047
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.047
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.046
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.046
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.046
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.045
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.045
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.044
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.044
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.044
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.044
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.044
|
Mouse |
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.043
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.043
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.043
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.043
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.043
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.043
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.042
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.042
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.042
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.042
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.042
|
Fly |
|
|
system process
|
GO:0003008 |
349 |
0.042
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.042
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.041
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.041
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.041
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.041
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.041
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.040
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.040
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.040
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.040
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.040
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.039
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.039
|
|
|
|
growth
|
GO:0040007 |
202 |
0.039
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.039
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.039
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.038
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.038
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.038
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.037
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.037
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.037
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.037
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.037
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.037
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.036
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.036
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.036
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.035
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.035
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.035
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.035
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.035
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.034
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.034
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.034
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.034
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.034
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.034
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.034
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.034
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.034
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.034
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.033
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.033
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.033
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.033
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.033
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.033
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.032
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.032
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.032
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.032
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.032
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.032
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.031
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.031
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.031
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.031
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.030
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.030
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.030
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.030
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.030
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.030
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.030
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.030
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.030
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.030
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.030
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.030
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.029
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.029
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.029
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.029
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.029
|
Mouse |
|
|
rna processing
|
GO:0006396 |
255 |
0.029
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.028
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
|
axoneme assembly
|
GO:0035082 |
3 |
0.028
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.028
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.028
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.027
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.027
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.027
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.027
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.027
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.027
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.027
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.027
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.027
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.027
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.026
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.026
|
|
|
|
aging
|
GO:0007568 |
66 |
0.026
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.026
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.026
|
Human |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.026
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.026
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
12 |
0.026
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.026
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.025
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.025
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.025
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.025
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.025
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.025
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.025
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.025
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.025
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.025
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.025
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.025
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.025
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
Human |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.024
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.024
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.024
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.024
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.024
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.024
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.024
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.024
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.024
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.024
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.024
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.024
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.024
|
Human |
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.024
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.024
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.023
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.023
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.023
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.023
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.023
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.023
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.023
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.023
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.023
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.023
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.023
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.023
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.022
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.022
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.022
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.022
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.022
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.022
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.022
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.022
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.022
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.022
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.022
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.022
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.022
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.021
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
6 |
0.021
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.021
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.021
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.021
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.021
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.021
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.021
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.021
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.021
|
Human |
|
|
head development
|
GO:0060322 |
108 |
0.021
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.021
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.021
|
Fly |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.021
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.021
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.021
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.021
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.021
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.020
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.020
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.020
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.020
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.020
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.020
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.020
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.020
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.020
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.020
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.020
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.020
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.020
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.020
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.020
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.020
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.020
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.020
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.020
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.020
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.020
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.019
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.019
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.019
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.019
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.019
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.019
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.019
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.019
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.019
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.019
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.019
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.019
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.019
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.019
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.019
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.018
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.018
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.018
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.018
|
Human |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.018
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.018
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.018
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.018
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.018
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.018
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.018
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.018
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.018
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.018
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.018
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.017
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.017
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.017
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.017
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.017
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.017
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.017
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.017
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.017
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.017
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.017
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.017
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.017
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.017
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.016
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.016
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.016
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.016
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.016
|
Human |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.016
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.016
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.016
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.016
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.016
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
19 |
0.016
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.016
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.016
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.016
|
Mouse |
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.016
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.016
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.016
|
Human |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.016
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.016
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.016
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.016
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.015
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.015
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.015
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.015
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.015
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.015
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.015
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.015
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.015
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.015
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.015
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.015
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.015
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.015
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.015
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.015
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.015
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.014
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.014
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.014
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.014
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.014
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.014
|
|
|
|
aorta morphogenesis
|
GO:0035909 |
1 |
0.014
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.014
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.014
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.014
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.014
|
Fly |
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.014
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.014
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.014
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.014
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.014
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.014
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.014
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.014
|
Fly |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.014
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.014
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.014
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.014
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.014
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.013
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.013
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.013
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.013
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.013
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.013
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.013
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.013
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.013
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.013
|
|
