|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.987
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.721
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.690
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.475
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.470
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.454
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.440
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.407
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.365
|
Mouse |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.337
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.336
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.320
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.316
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.310
|
Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.310
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.286
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.283
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.276
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.267
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.260
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.255
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.251
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.248
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.245
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.242
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.234
|
Worm |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.224
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.218
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.213
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.204
|
|
|
|
fas signaling pathway
|
GO:0036337 |
3 |
0.200
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.199
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.192
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.192
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.183
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.182
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.182
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.181
|
Mouse |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.176
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.173
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.170
|
Yeast |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.166
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.166
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.161
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.157
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.154
|
Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.151
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.151
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.146
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.144
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.143
|
Yeast |
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.142
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.141
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.139
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.134
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.132
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.130
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.127
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.126
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.126
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.126
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.124
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.124
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.122
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.119
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.117
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.115
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.114
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.111
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.111
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.111
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.110
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.109
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.105
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.104
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.104
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.103
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.103
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.103
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.103
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.102
|
Worm |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.101
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.101
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.098
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.098
|
Yeast |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.097
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.096
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.094
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.093
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.092
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.092
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.092
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.092
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.091
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.091
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.084
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.080
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.078
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.077
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.076
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.076
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.076
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.075
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.075
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.075
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.075
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.075
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.074
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.073
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.072
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.072
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.072
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.070
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.070
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.069
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.069
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.068
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.068
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.068
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.067
|
Yeast |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.067
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.065
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.064
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.064
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.064
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.063
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.063
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.063
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.063
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.063
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.063
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.062
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.061
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.061
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.060
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.060
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.059
|
Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.058
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.058
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.058
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.057
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.057
|
Mouse |
|
|
histone methylation
|
GO:0016571 |
60 |
0.056
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.056
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.056
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.055
|
Mouse |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.054
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.054
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.054
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.053
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.053
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.053
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.053
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.052
|
|
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
0.052
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.052
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.051
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.050
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.049
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.049
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.049
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.049
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.049
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.048
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.048
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.047
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.047
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.047
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.047
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.046
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
37 |
0.046
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.046
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.045
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.045
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.045
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.044
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.044
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.044
|
|
|
|
pharyngeal system development
|
GO:0060037 |
2 |
0.044
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.043
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.043
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.043
|
Worm |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.043
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.043
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.043
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.042
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.042
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.042
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.042
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.042
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.042
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.042
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.041
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.041
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.041
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.040
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.040
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.040
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.040
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.040
|
Yeast |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.040
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.040
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.040
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.040
|
|
|
|
cd8 positive alpha beta t cell differentiation
|
GO:0043374 |
1 |
0.039
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.039
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.039
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.039
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.039
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.038
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.037
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.037
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.037
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.037
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.037
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.037
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.036
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.036
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.036
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.036
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.035
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.035
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.035
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
1 |
0.035
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.035
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.035
|
|
|
|
thalamus development
|
GO:0021794 |
2 |
0.035
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
7 |
0.035
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.034
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.034
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.034
|
Worm |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.034
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.034
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.034
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.033
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.033
|
Worm |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.033
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.033
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.033
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.032
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.032
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.032
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.032
|
|
|
|
avoidance of host defenses
|
GO:0044413 |
2 |
0.032
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.032
|
|
|
|
intestinal epithelial cell differentiation
|
GO:0060575 |
3 |
0.031
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.031
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.031
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.031
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.031
|
|
|
|
sebaceous gland development
|
GO:0048733 |
1 |
0.031
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.031
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.031
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.030
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.030
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.030
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.030
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.030
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.030
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.029
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.029
|
|
|
|
memory
|
GO:0007613 |
3 |
0.029
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.029
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.029
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.029
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.029
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.028
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.028
|
Worm |
|
|
epidermis development
|
GO:0008544 |
59 |
0.028
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.028
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.028
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.028
|
Worm |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.027
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.027
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.027
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.027
|
|
|
|
dna integration
|
GO:0015074 |
3 |
0.027
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.027
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
|
|
|
growth
|
GO:0040007 |
202 |
0.027
|
Worm |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.026
|
|
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
0.026
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.026
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.026
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.026
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.026
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.026
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.026
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.026
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.026
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.026
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.026
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.025
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.025
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.025
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.025
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.025
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.025
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.025
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.025
|
Worm |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.025
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.025
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.025
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.025
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.024
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.024
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.024
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.024
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.024
|
Worm |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.024
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.024
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.024
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.024
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.023
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.023
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.023
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.023
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.023
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.023
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.023
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.022
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.022
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.022
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.022
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.022
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.022
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.022
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.022
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.022
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.022
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.022
|
Worm |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.021
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.021
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.021
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.021
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.021
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.021
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.021
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.021
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.021
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.021
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.020
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.020
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.020
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
5 |
0.020
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.020
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.020
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.020
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.020
|
Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.020
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.020
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.020
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.020
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.020
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.020
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.020
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.020
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.019
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.019
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.019
|
|
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.019
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.019
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.019
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.019
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.019
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.019
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.019
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.018
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.018
|
Worm |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.018
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.018
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.018
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.018
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.018
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.018
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.018
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.018
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.018
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.018
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.018
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.018
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.018
|
Yeast |
|
|
negative regulation of extracellular matrix organization
|
GO:1903054 |
3 |
0.018
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.018
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.018
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.018
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.017
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.017
|
Yeast |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.017
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.017
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.017
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.017
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.017
|
Mouse |
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.017
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.017
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.017
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.017
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.017
|
Human |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.017
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.017
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.017
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.016
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.016
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.016
|
Mouse |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.016
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.016
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.016
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.016
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.016
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.016
|
Worm |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.016
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.016
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.016
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.016
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.016
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.016
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.016
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
2 |
0.016
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.016
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.016
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.016
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.016
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.015
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.015
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.015
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.015
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.015
|
|
|
|
regulation of transforming growth factor beta production
|
GO:0071634 |
13 |
0.015
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.015
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.015
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.015
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.015
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.015
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.015
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.015
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.015
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.015
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.015
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.015
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.015
|
|
|
|
dna methylation or demethylation
|
GO:0044728 |
19 |
0.015
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.015
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.015
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.015
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.014
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.014
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.014
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.014
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.014
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.014
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.014
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.014
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.014
|
Mouse |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.014
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.014
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.014
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.014
|
Yeast |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.014
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.014
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.014
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.014
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.014
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.014
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.014
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.014
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.014
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.014
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.013
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.013
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.013
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.013
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.013
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.013
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.013
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.013
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.013
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.013
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.013
|
|
