Homo sapiens

139 known processes

P2RX7

purinergic receptor P2X, ligand-gated ion channel, 7

(Aliases: P2X7,MGC20089)

P2RX7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.113
cellular amino acid metabolic process GO:0006520 116 0.111
cellular amine metabolic process GO:0044106 41 0.097
cellular ketone metabolic process GO:0042180 80 0.094
amine metabolic process GO:0009308 44 0.093
immune response GO:0006955 307 0.087
positive regulation of transport GO:0051050 336 0.083
cytokine production GO:0001816 247 0.083
regulation of cellular amino acid metabolic process GO:0006521 6 0.080
regulation of cellular ketone metabolic process GO:0010565 50 0.079
positive regulation of cellular amine metabolic process GO:0033240 7 0.078
defense response GO:0006952 315 0.075
regulation of cellular amine metabolic process GO:0033238 11 0.073
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.067
purine ribonucleotide catabolic process GO:0009154 404 0.067
post embryonic development GO:0009791 2 0.064
secretion GO:0046903 254 0.064
regulation of protein localization GO:0032880 296 0.063
secretion by cell GO:0032940 226 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.062
small gtpase mediated signal transduction GO:0007264 78 0.062
ras protein signal transduction GO:0007265 73 0.062
cell adhesion GO:0007155 325 0.059
locomotory behavior GO:0007626 1 0.059
purine ribonucleoside metabolic process GO:0046128 437 0.058
vesicle mediated transport GO:0016192 371 0.057
system process GO:0003008 349 0.056
Human Rat
lipid metabolic process GO:0006629 381 0.056
nucleoside triphosphate metabolic process GO:0009141 422 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
ribonucleoside triphosphate catabolic process GO:0009203 391 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.053
positive regulation of immune system process GO:0002684 283 0.053
biological adhesion GO:0022610 331 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.053
purine nucleotide catabolic process GO:0006195 405 0.052
regulation of response to external stimulus GO:0032101 222 0.052
nucleoside phosphate catabolic process GO:1901292 412 0.052
nucleoside catabolic process GO:0009164 408 0.052
ribonucleoside catabolic process GO:0042454 406 0.052
immune effector process GO:0002252 159 0.051
glycosyl compound catabolic process GO:1901658 413 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.050
regulation of secretion GO:0051046 194 0.050
negative regulation of multicellular organismal process GO:0051241 317 0.050
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.049
nucleotide catabolic process GO:0009166 408 0.049
purine nucleoside catabolic process GO:0006152 398 0.049
multicellular organismal aging GO:0010259 3 0.047
positive regulation of hydrolase activity GO:0051345 331 0.047
ribonucleotide catabolic process GO:0009261 405 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
Rat
response to external biotic stimulus GO:0043207 261 0.046
positive regulation of protein phosphorylation GO:0001934 313 0.046
Rat
regulation of immune response GO:0050776 201 0.046
regulation of cell differentiation GO:0045595 393 0.045
cellular lipid metabolic process GO:0044255 303 0.044
organophosphate catabolic process GO:0046434 430 0.044
purine containing compound catabolic process GO:0072523 411 0.044
determination of adult lifespan GO:0008340 2 0.043
gtp catabolic process GO:0006184 237 0.043
innate immune response GO:0045087 178 0.043
positive regulation of cytokine production GO:0001819 167 0.042
rho protein signal transduction GO:0007266 26 0.041
response to cytokine GO:0034097 232 0.041
gtp metabolic process GO:0046039 239 0.040
neuromuscular junction development GO:0007528 3 0.040
regulation of cytokine production GO:0001817 232 0.040
negative regulation of cell death GO:0060548 345 0.040
positive regulation of immune response GO:0050778 159 0.040
regulation of kinase activity GO:0043549 314 0.039
Rat
regulation of locomotion GO:0040012 329 0.039
regulation of cellular component movement GO:0051270 334 0.039
regulation of establishment of protein localization GO:0070201 242 0.039
response to oxygen containing compound GO:1901700 369 0.038
single organism membrane organization GO:0044802 268 0.038
response to other organism GO:0051707 261 0.038
single organism cellular localization GO:1902580 332 0.037
regulation of transferase activity GO:0051338 355 0.037
Rat
guanosine containing compound catabolic process GO:1901069 239 0.037
cytoplasmic transport GO:0016482 379 0.037
actin filament based process GO:0030029 224 0.037
negative regulation of apoptotic process GO:0043066 316 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.036
female gamete generation GO:0007292 2 0.036
cell activation GO:0001775 213 0.036
enzyme linked receptor protein signaling pathway GO:0007167 303 0.036
metal ion transport GO:0030001 272 0.036
regulation of cellular component biogenesis GO:0044087 281 0.035
cation transport GO:0006812 331 0.035
regulation of secretion by cell GO:1903530 177 0.035
peptidyl tyrosine modification GO:0018212 170 0.035
response to biotic stimulus GO:0009607 276 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
nervous system development GO:0007399 293 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
adult locomotory behavior GO:0008344 1 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
membrane organization GO:0061024 292 0.033
negative regulation of protein metabolic process GO:0051248 391 0.033
regulation of nucleoside metabolic process GO:0009118 209 0.032
response to virus GO:0009615 126 0.032
ion homeostasis GO:0050801 230 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
Human
regulation of protein transport GO:0051223 213 0.032
immune response regulating signaling pathway GO:0002764 97 0.031
regulation of defense response GO:0031347 154 0.031
oogenesis GO:0048477 2 0.031
positive regulation of catabolic process GO:0009896 310 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
memory GO:0007613 3 0.031
chemical homeostasis GO:0048878 306 0.030
regulation of leukocyte activation GO:0002694 115 0.030
lipid biosynthetic process GO:0008610 177 0.030
response to abiotic stimulus GO:0009628 336 0.030
regulation of purine nucleotide catabolic process GO:0033121 205 0.030
cell development GO:0048468 328 0.030
cellular homeostasis GO:0019725 196 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
regulation of lymphocyte activation GO:0051249 103 0.029
positive regulation of transferase activity GO:0051347 227 0.029
Rat
regulation of protein kinase activity GO:0045859 289 0.029
Rat
regulation of gtp catabolic process GO:0033124 180 0.029
hematopoietic or lymphoid organ development GO:0048534 186 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
regulation of cellular response to stress GO:0080135 244 0.029
immune system development GO:0002520 195 0.029
positive regulation of cell death GO:0010942 263 0.029
Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
activation of immune response GO:0002253 114 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.028
regulation of mapk cascade GO:0043408 262 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
cell morphogenesis GO:0000902 296 0.028
dephosphorylation GO:0016311 209 0.028
regulation of cell cycle GO:0051726 393 0.028
regulation of cell activation GO:0050865 125 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
intracellular protein transport GO:0006886 270 0.028
nitrogen compound transport GO:0071705 191 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
Rat
regulation of protein secretion GO:0050708 86 0.027
regulation of intracellular transport GO:0032386 195 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
defense response to other organism GO:0098542 129 0.027
mapk cascade GO:0000165 288 0.027
protein secretion GO:0009306 98 0.027
cellular ion homeostasis GO:0006873 168 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
leukocyte activation GO:0045321 164 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
response to bacterium GO:0009617 144 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
cellular cation homeostasis GO:0030003 163 0.026
positive regulation of cell proliferation GO:0008284 301 0.026
apoptotic signaling pathway GO:0097190 268 0.026
Human Rat
regulation of ras protein signal transduction GO:0046578 155 0.025
protein localization to organelle GO:0033365 280 0.025
cellular component morphogenesis GO:0032989 314 0.025
positive regulation of mapk cascade GO:0043410 190 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.025
single organismal cell cell adhesion GO:0016337 148 0.025
calcium ion transport GO:0006816 147 0.025
regulation of gtpase activity GO:0043087 180 0.025
actin cytoskeleton organization GO:0030036 207 0.024
cell projection organization GO:0030030 252 0.024
lymphocyte activation GO:0046649 133 0.024
single organism cell adhesion GO:0098602 179 0.024
microtubule based process GO:0007017 210 0.024
defense response to virus GO:0051607 71 0.024
negative regulation of transport GO:0051051 176 0.024
regulation of innate immune response GO:0045088 97 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
hindbrain development GO:0030902 3 0.024
regulation of cell adhesion GO:0030155 166 0.024
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of cell motility GO:2000145 299 0.023
protein catabolic process GO:0030163 325 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
taxis GO:0042330 157 0.023
positive regulation of protein transport GO:0051222 135 0.023
negative regulation of developmental process GO:0051093 247 0.023
positive regulation of synaptic transmission GO:0050806 4 0.023
divalent metal ion transport GO:0070838 152 0.023
positive regulation of secretion GO:0051047 116 0.023
positive regulation of kinase activity GO:0033674 204 0.023
Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.023
positive regulation of developmental process GO:0051094 314 0.023
protein processing GO:0016485 226 0.022
transmembrane transport GO:0055085 399 0.022
regulation of proteolysis GO:0030162 293 0.022
hemopoiesis GO:0030097 180 0.022
endocytosis GO:0006897 159 0.022
neurological system process GO:0050877 163 0.022
Human Rat
regulation of immune effector process GO:0002697 91 0.022
regulation of multi organism process GO:0043900 157 0.022
response to organic cyclic compound GO:0014070 204 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
regulation of t cell activation GO:0050863 77 0.022
regulation of cytokine secretion GO:0050707 57 0.022
regulation of synaptic plasticity GO:0048167 3 0.022
regulation of cytoskeleton organization GO:0051493 177 0.022
Rat
negative regulation of cellular component organization GO:0051129 235 0.022
carbohydrate metabolic process GO:0005975 207 0.022
negative regulation of immune system process GO:0002683 136 0.022
cation homeostasis GO:0055080 189 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
endomembrane system organization GO:0010256 196 0.021
chemotaxis GO:0006935 157 0.021
cellular response to cytokine stimulus GO:0071345 181 0.021
protein maturation GO:0051604 233 0.021
mitotic cell cycle GO:0000278 326 0.021
regeneration GO:0031099 4 0.021
maintenance of location GO:0051235 112 0.021
small molecule biosynthetic process GO:0044283 157 0.021
immune response activating signal transduction GO:0002757 90 0.021
cellular protein complex assembly GO:0043623 188 0.021
response to lipid GO:0033993 206 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
cellular metal ion homeostasis GO:0006875 146 0.020
positive regulation of lymphocyte activation GO:0051251 73 0.020
protein ubiquitination GO:0016567 314 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
generation of neurons GO:0048699 152 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
negative regulation of cell cycle GO:0045786 193 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
Rat
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
regulation of peptidase activity GO:0052547 180 0.020
segmentation GO:0035282 4 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
regulation of ras gtpase activity GO:0032318 128 0.020
positive regulation of cell activation GO:0050867 81 0.019
oocyte differentiation GO:0009994 2 0.019
oocyte development GO:0048599 1 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
cytokine secretion GO:0050663 64 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
epithelial cell migration GO:0010631 119 0.019
regulation of cell migration GO:0030334 289 0.019
ion transmembrane transport GO:0034220 338 0.019
microtubule cytoskeleton organization GO:0000226 176 0.019
positive regulation of proteolysis GO:0045862 142 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
cell substrate adhesion GO:0031589 132 0.019
protein targeting GO:0006605 187 0.019
protein autophosphorylation GO:0046777 123 0.019
serotonin transport GO:0006837 3 0.019
metal ion homeostasis GO:0055065 169 0.019
circulatory system development GO:0072359 262 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
divalent inorganic cation transport GO:0072511 158 0.018
cellular response to lipid GO:0071396 127 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
associative learning GO:0008306 1 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
cellular response to abiotic stimulus GO:0071214 117 0.018
phospholipid metabolic process GO:0006644 99 0.018
regulation of regulatory t cell differentiation GO:0045589 4 0.018
glycerolipid metabolic process GO:0046486 107 0.018
positive regulation of innate immune response GO:0045089 79 0.018
mitotic cell cycle process GO:1903047 286 0.018
cellular chemical homeostasis GO:0055082 180 0.018
oxidation reduction process GO:0055114 396 0.018
cell part morphogenesis GO:0032990 137 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of mononuclear cell proliferation GO:0032944 65 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
response to organonitrogen compound GO:0010243 156 0.017
protein oligomerization GO:0051259 173 0.017
Human
rhythmic behavior GO:0007622 2 0.017
cell growth GO:0016049 160 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
cellular response to external stimulus GO:0071496 111 0.017
detection of stimulus GO:0051606 85 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
angiogenesis GO:0001525 147 0.017
growth GO:0040007 202 0.017
tissue migration GO:0090130 119 0.017
ameboidal type cell migration GO:0001667 135 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of actin filament based process GO:0032970 141 0.017
protein localization to membrane GO:0072657 160 0.017
activation of protein kinase activity GO:0032147 90 0.017
neurogenesis GO:0022008 169 0.017
long term memory GO:0007616 2 0.016
regulation of metal ion transport GO:0010959 120 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
circadian behavior GO:0048512 2 0.016
alcohol metabolic process GO:0006066 114 0.016
detection of muramyl dipeptide GO:0032498 1 0.016
cation transmembrane transport GO:0098655 238 0.016
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
t cell activation GO:0042110 99 0.016
sulfur compound metabolic process GO:0006790 101 0.016
chromatin modification GO:0016568 298 0.016
regulation of calcium ion transport GO:0051924 79 0.016
nuclear transport GO:0051169 179 0.016
histone modification GO:0016570 251 0.016
response to growth factor GO:0070848 205 0.016
cardiovascular system development GO:0072358 262 0.016
regulation of protein complex assembly GO:0043254 147 0.016
negative regulation of alpha beta t cell activation GO:0046636 3 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of growth GO:0040008 165 0.015
blastoderm segmentation GO:0007350 2 0.015
leukocyte mediated immunity GO:0002443 59 0.015
epithelium migration GO:0090132 119 0.015
regulation of cell cycle process GO:0010564 266 0.015
compound eye development GO:0048749 1 0.015
positive regulation of defense response GO:0031349 87 0.015
neuroblast proliferation GO:0007405 4 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
Rat
activation of innate immune response GO:0002218 55 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
Human
positive regulation of leukocyte activation GO:0002696 80 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
spermatid development GO:0007286 4 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
positive regulation of organelle organization GO:0010638 195 0.015
Rat
anion transport GO:0006820 161 0.015
cellular protein catabolic process GO:0044257 261 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
response to wounding GO:0009611 168 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
blood vessel morphogenesis GO:0048514 162 0.015
cytokine biosynthetic process GO:0042089 37 0.015
multi organism cellular process GO:0044764 156 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.015
motor neuron axon guidance GO:0008045 2 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
myeloid cell differentiation GO:0030099 117 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
neuron differentiation GO:0030182 138 0.015
organic acid biosynthetic process GO:0016053 97 0.015
leukocyte proliferation GO:0070661 74 0.015
regulation of rho protein signal transduction GO:0035023 79 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
regulation of microtubule based process GO:0032886 74 0.014
endosomal transport GO:0016197 129 0.014
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
positive regulation of protein secretion GO:0050714 60 0.014
actin mediated cell contraction GO:0070252 12 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
response to nitrogen compound GO:1901698 184 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
limbic system development GO:0021761 3 0.014
sensory perception of smell GO:0007608 2 0.014
organelle assembly GO:0070925 176 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
sex determination GO:0007530 3 0.014
regulation of microtubule cytoskeleton organization GO:0070507 61 0.014
leukocyte migration GO:0050900 107 0.014
detection of chemical stimulus GO:0009593 55 0.014
cell projection morphogenesis GO:0048858 129 0.014
sensory perception of pain GO:0019233 4 0.014
plasma membrane organization GO:0007009 115 0.014
neurotransmitter secretion GO:0007269 4 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
Human
visual behavior GO:0007632 2 0.014
regulation of cytokine biosynthetic process GO:0042035 35 0.014
nucleotide biosynthetic process GO:0009165 109 0.014
chromatin organization GO:0006325 351 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
regulation of protein catabolic process GO:0042176 155 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
actin filament organization GO:0007015 128 0.014
neuron projection regeneration GO:0031102 1 0.014
anterior posterior axis specification GO:0009948 2 0.014
salivary gland morphogenesis GO:0007435 4 0.014
neuron development GO:0048666 113 0.014
covalent chromatin modification GO:0016569 254 0.014
protein localization to nucleus GO:0034504 136 0.014
neuron projection development GO:0031175 106 0.013
positive regulation of map kinase activity GO:0043406 80 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
glycoprotein metabolic process GO:0009100 110 0.013
negative regulation of transferase activity GO:0051348 124 0.013
interspecies interaction between organisms GO:0044419 156 0.013
regulation of cell development GO:0060284 161 0.013
cell type specific apoptotic process GO:0097285 125 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.013
cytokine metabolic process GO:0042107 38 0.013
response to radiation GO:0009314 151 0.013
regulation of dendritic cell apoptotic process GO:2000668 4 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
response to axon injury GO:0048678 1 0.013
metencephalon development GO:0022037 2 0.013
adaptive immune response GO:0002250 49 0.013
positive regulation of regulatory t cell differentiation GO:0045591 3 0.013
regulation of interleukin 10 secretion GO:2001179 4 0.013
atp metabolic process GO:0046034 176 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
negative regulation of secretion by cell GO:1903531 52 0.013
cell cycle phase transition GO:0044770 173 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of homeostatic process GO:0032844 121 0.013
response to inorganic substance GO:0010035 127 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
regulation of membrane potential GO:0042391 95 0.013
post embryonic organ development GO:0048569 1 0.013
monovalent inorganic cation transport GO:0015672 128 0.013
Rat
regulation of eosinophil activation GO:1902566 2 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
cell projection assembly GO:0030031 126 0.013
regulation of map kinase activity GO:0043405 108 0.013
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.013
regulation of dephosphorylation GO:0035303 96 0.013
central nervous system development GO:0007417 123 0.013
organic anion transport GO:0015711 103 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
Rat
regulation of meiotic cell cycle GO:0051445 4 0.013
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
response to metal ion GO:0010038 84 0.013
regulation of mitotic cell cycle GO:0007346 189 0.012
cell matrix adhesion GO:0007160 85 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
lipid localization GO:0010876 106 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
cd8 positive alpha beta t cell activation GO:0036037 3 0.012
inflammatory response GO:0006954 79 0.012
tripartite regional subdivision GO:0007351 2 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
positive regulation of cell migration GO:0030335 172 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
behavior GO:0007610 112 0.012
circulatory system process GO:0003013 113 0.012
Human
actin filament based movement GO:0030048 17 0.012
mating GO:0007618 1 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
calcium ion homeostasis GO:0055074 122 0.012
negative regulation of growth GO:0045926 97 0.012
regulation of protein processing GO:0070613 150 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
regulation of ion transport GO:0043269 189 0.012
head development GO:0060322 108 0.012
viral life cycle GO:0019058 132 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
response to fungus GO:0009620 4 0.012
lymphocyte proliferation GO:0046651 70 0.012

P2RX7 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.045
musculoskeletal system disease DOID:17 223 0.036
inherited metabolic disorder DOID:655 242 0.035
sensory system disease DOID:0050155 203 0.032
nervous system disease DOID:863 431 0.032
immune system disease DOID:2914 155 0.029
central nervous system disease DOID:331 186 0.027
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.024
connective tissue disease DOID:65 109 0.022
disease of cellular proliferation DOID:14566 174 0.021
cancer DOID:162 167 0.021
organ system cancer DOID:0050686 164 0.021
retinal disease DOID:5679 118 0.019
bone disease DOID:0080001 88 0.016
neurodegenerative disease DOID:1289 102 0.016
retinal degeneration DOID:8466 89 0.014
brain disease DOID:936 73 0.013
muscular disease DOID:0080000 114 0.013
muscle tissue disease DOID:66 113 0.013