Homo sapiens

16 known processes

SAE1

SUMO1 activating enzyme subunit 1

(Aliases: AOS1,FLJ3091,HSPC140,UBLE1A,SUA1)

SAE1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle GO:0000278 326 0.521
Fly
microtubule based process GO:0007017 210 0.436
microtubule cytoskeleton organization GO:0000226 176 0.204
cellular macromolecular complex assembly GO:0034622 324 0.180
mitotic cell cycle process GO:1903047 286 0.174
regulation of nuclear division GO:0051783 65 0.165
single organism nuclear import GO:1902593 104 0.151
protein modification by small protein conjugation GO:0032446 342 0.149
nuclear division GO:0000280 128 0.149
cellular macromolecule catabolic process GO:0044265 380 0.142
chromatin organization GO:0006325 351 0.139
purine ribonucleoside metabolic process GO:0046128 437 0.137
ribonucleotide catabolic process GO:0009261 405 0.136
small gtpase mediated signal transduction GO:0007264 78 0.134
positive regulation of cellular catabolic process GO:0031331 284 0.134
nucleoside triphosphate catabolic process GO:0009143 394 0.130
modification dependent macromolecule catabolic process GO:0043632 212 0.125
positive regulation of catabolic process GO:0009896 310 0.124
nuclear transport GO:0051169 179 0.119
protein desumoylation GO:0016926 4 0.117
determination of adult lifespan GO:0008340 2 0.116
intracellular protein transport GO:0006886 270 0.116
cell division GO:0051301 168 0.115
response to abiotic stimulus GO:0009628 336 0.113
regulation of cell cycle process GO:0010564 266 0.107
protein localization to nucleus GO:0034504 136 0.105
regulation of proteolysis GO:0030162 293 0.104
ras protein signal transduction GO:0007265 73 0.098
regulation of cellular component biogenesis GO:0044087 281 0.096
multicellular organismal aging GO:0010259 3 0.095
single organism cellular localization GO:1902580 332 0.094
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.092
regulation of protein localization GO:0032880 296 0.090
chromosome segregation GO:0007059 114 0.089
purine containing compound catabolic process GO:0072523 411 0.087
ribonucleoside triphosphate metabolic process GO:0009199 412 0.087
ribonucleoside catabolic process GO:0042454 406 0.086
response to organic cyclic compound GO:0014070 204 0.085
spindle organization GO:0007051 53 0.083
protein import into nucleus GO:0006606 104 0.081
cytoplasmic transport GO:0016482 379 0.079
central nervous system projection neuron axonogenesis GO:0021952 3 0.077
protein targeting to nucleus GO:0044744 104 0.077
locomotory behavior GO:0007626 1 0.075
negative regulation of cellular component organization GO:0051129 235 0.074
regulation of nucleotide metabolic process GO:0006140 269 0.074
pharynx development GO:0060465 1 0.073
regulation of gtp catabolic process GO:0033124 180 0.070
positive regulation of gtp catabolic process GO:0033126 166 0.070
mitotic spindle organization GO:0007052 27 0.070
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.068
positive regulation of nucleotide metabolic process GO:0045981 230 0.068
regulation of protein complex assembly GO:0043254 147 0.068
purine nucleotide catabolic process GO:0006195 405 0.066
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.066
positive regulation of cellular component biogenesis GO:0044089 158 0.065
protein localization to organelle GO:0033365 280 0.065
nucleoside phosphate catabolic process GO:1901292 412 0.064
organophosphate catabolic process GO:0046434 430 0.064
organophosphate biosynthetic process GO:0090407 163 0.063
mitotic nuclear division GO:0007067 119 0.063
positive regulation of cellular component organization GO:0051130 376 0.061
regulation of intracellular transport GO:0032386 195 0.060
regulation of nucleoside metabolic process GO:0009118 209 0.060
purine nucleoside triphosphate catabolic process GO:0009146 392 0.060
proteasomal protein catabolic process GO:0010498 176 0.059
response to growth factor GO:0070848 205 0.059
vesicle mediated transport GO:0016192 371 0.057
regulation of gtpase activity GO:0043087 180 0.057
positive regulation of nucleotide catabolic process GO:0030813 185 0.057
guanosine containing compound catabolic process GO:1901069 239 0.056
ubiquitin dependent protein catabolic process GO:0006511 206 0.055
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.054
positive regulation of hydrolase activity GO:0051345 331 0.052
protein ubiquitination GO:0016567 314 0.052
regulation of gene expression epigenetic GO:0040029 73 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.051
purine ribonucleotide catabolic process GO:0009154 404 0.051
positive regulation of transferase activity GO:0051347 227 0.051
gtp catabolic process GO:0006184 237 0.051
sex differentiation GO:0007548 45 0.050
nuclear import GO:0051170 106 0.049
cellular amino acid metabolic process GO:0006520 116 0.049
nucleocytoplasmic transport GO:0006913 176 0.048
response to oxygen containing compound GO:1901700 369 0.048
regulation of microtubule based process GO:0032886 74 0.047
nucleoside triphosphate metabolic process GO:0009141 422 0.046
protein import GO:0017038 130 0.045
meiotic chromosome segregation GO:0045132 4 0.045
regulation of cell division GO:0051302 116 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
histone modification GO:0016570 251 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.044
single organism membrane organization GO:0044802 268 0.043
positive regulation of nucleoside metabolic process GO:0045979 186 0.043
organelle fission GO:0048285 149 0.043
positive regulation of gtpase activity GO:0043547 166 0.042
negative regulation of intracellular transport GO:0032387 60 0.042
modification dependent protein catabolic process GO:0019941 209 0.042
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.041
nuclear migration GO:0007097 1 0.040
gtp metabolic process GO:0046039 239 0.040
apoptotic signaling pathway GO:0097190 268 0.039
central nervous system neuron axonogenesis GO:0021955 3 0.038
cellular ketone metabolic process GO:0042180 80 0.038
single organism reproductive process GO:0044702 98 0.038
Worm
regulation of cell cycle GO:0051726 393 0.038
Fly
developmental process involved in reproduction GO:0003006 66 0.037
Worm
double strand break repair GO:0006302 101 0.037
meiosis i GO:0007127 4 0.037
regulation of establishment of protein localization GO:0070201 242 0.037
regulation of immune response GO:0050776 201 0.036
regulation of small gtpase mediated signal transduction GO:0051056 156 0.035
regulation of nucleotide catabolic process GO:0030811 205 0.034
response to hormone GO:0009725 175 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
cellular response to endogenous stimulus GO:0071495 336 0.033
purine nucleoside catabolic process GO:0006152 398 0.033
establishment of protein localization to organelle GO:0072594 172 0.032
nucleotide catabolic process GO:0009166 408 0.032
i kappab kinase nf kappab signaling GO:0007249 166 0.032
negative regulation of protein processing GO:0010955 142 0.032
protein dna complex assembly GO:0065004 64 0.032
regulation of protein transport GO:0051223 213 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
defense response GO:0006952 315 0.031
response to hypoxia GO:0001666 96 0.031
post embryonic development GO:0009791 2 0.030
Worm
protein dna complex subunit organization GO:0071824 80 0.030
positive regulation of transport GO:0051050 336 0.030
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.030
chromatin modification GO:0016568 298 0.029
protein catabolic process GO:0030163 325 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
cell development GO:0048468 328 0.029
Worm
regulation of binding GO:0051098 111 0.029
protein polymerization GO:0051258 71 0.029
protein modification by small protein removal GO:0070646 92 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
neurogenesis GO:0022008 169 0.028
Fly
cellular component morphogenesis GO:0032989 314 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
guanosine containing compound metabolic process GO:1901068 244 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
generation of neurons GO:0048699 152 0.027
female gamete generation GO:0007292 2 0.027
Worm
embryo development GO:0009790 123 0.026
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
regulation of dna binding GO:0051101 37 0.026
protein targeting GO:0006605 187 0.026
regulation of nucleocytoplasmic transport GO:0046822 98 0.026
negative regulation of transport GO:0051051 176 0.026
cellular response to dna damage stimulus GO:0006974 379 0.025
regulation of mapk cascade GO:0043408 262 0.025
embryo development ending in birth or egg hatching GO:0009792 34 0.025
Worm
nitrogen compound transport GO:0071705 191 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
mitotic cell cycle phase transition GO:0044772 162 0.025
cell cycle phase transition GO:0044770 173 0.025
regulation of peptidase activity GO:0052547 180 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
negative regulation of protein transport GO:0051224 75 0.024
nervous system development GO:0007399 293 0.024
Fly
endomembrane system organization GO:0010256 196 0.023
regulation of protein catabolic process GO:0042176 155 0.023
cytokinesis GO:0000910 96 0.023
protein maturation GO:0051604 233 0.023
response to oxygen levels GO:0070482 100 0.023
positive regulation of cell death GO:0010942 263 0.023
neuron differentiation GO:0030182 138 0.022
cell projection organization GO:0030030 252 0.022
spindle elongation GO:0051231 4 0.022
toll signaling pathway GO:0008063 2 0.022
chemical homeostasis GO:0048878 306 0.022
oogenesis GO:0048477 2 0.022
Worm
g2 dna damage checkpoint GO:0031572 26 0.022
response to external biotic stimulus GO:0043207 261 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
dna damage checkpoint GO:0000077 68 0.021
cellular response to organic cyclic compound GO:0071407 127 0.021
reproductive structure development GO:0048608 55 0.021
positive regulation of proteolysis GO:0045862 142 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
neuron development GO:0048666 113 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
regulation of ras protein signal transduction GO:0046578 155 0.020
negative regulation of locomotion GO:0040013 118 0.020
establishment of organelle localization GO:0051656 59 0.020
regulation of mitosis GO:0007088 63 0.020
dna conformation change GO:0071103 113 0.020
dna repair GO:0006281 198 0.020
endocytosis GO:0006897 159 0.020
reproductive process GO:0022414 106 0.020
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.020
oocyte differentiation GO:0009994 2 0.020
nucleotide biosynthetic process GO:0009165 109 0.020
regulation of cellular protein catabolic process GO:1903362 96 0.020
adult locomotory behavior GO:0008344 1 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.019
regulation of locomotion GO:0040012 329 0.019
nucleoside catabolic process GO:0009164 408 0.019
neuron projection development GO:0031175 106 0.019
cellular protein catabolic process GO:0044257 261 0.019
organelle localization GO:0051640 84 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
regulation of microtubule cytoskeleton organization GO:0070507 61 0.018
cellular response to lipid GO:0071396 127 0.018
establishment of nucleus localization GO:0040023 1 0.018
response to transforming growth factor beta GO:0071559 94 0.018
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.018
cell morphogenesis GO:0000902 296 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
chromatin remodeling GO:0006338 55 0.017
nucleus localization GO:0051647 1 0.017
maintenance of location GO:0051235 112 0.017
negative regulation of protein modification process GO:0031400 200 0.017
positive regulation of protein complex assembly GO:0031334 86 0.017
histone methylation GO:0016571 60 0.017
central nervous system development GO:0007417 123 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
oocyte development GO:0048599 1 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
Fly
cellular amine metabolic process GO:0044106 41 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
negative regulation of organelle organization GO:0010639 126 0.015
regulation of defense response GO:0031347 154 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
regulation of meiosis GO:0040020 3 0.015
protein processing GO:0016485 226 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
methylation GO:0032259 106 0.015
regulation of kinase activity GO:0043549 314 0.015
dna replication GO:0006260 116 0.015
regulation of protein ubiquitination GO:0031396 95 0.014
rna interference GO:0016246 4 0.014
microtubule polymerization or depolymerization GO:0031109 37 0.014
behavior GO:0007610 112 0.014
mapk cascade GO:0000165 288 0.014
negative regulation of proteolysis GO:0045861 132 0.014
microtubule polymerization GO:0046785 18 0.014
regulation of cellular response to stress GO:0080135 244 0.014
protein tetramerization GO:0051262 47 0.014
positive regulation of organelle organization GO:0010638 195 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.013
regulation of muscle system process GO:0090257 53 0.013
regulation of transferase activity GO:0051338 355 0.013
nuclear export GO:0051168 69 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
cell cell signaling GO:0007267 155 0.013
ribonucleoprotein complex subunit organization GO:0071826 81 0.013
negative regulation of toll signaling pathway GO:0045751 1 0.013
cell part morphogenesis GO:0032990 137 0.013
protein sumoylation GO:0016925 25 0.013
gene silencing GO:0016458 49 0.013
fertilization GO:0009566 12 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
amine metabolic process GO:0009308 44 0.013
gonad development GO:0008406 34 0.013
regulation of protein stability GO:0031647 87 0.013
protein methylation GO:0006479 74 0.013
cellular protein complex assembly GO:0043623 188 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.012
response to biotic stimulus GO:0009607 276 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of protein ubiquitination GO:0031398 53 0.012
reproduction GO:0000003 63 0.012
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
Fly
organelle assembly GO:0070925 176 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
positive regulation of protein catabolic process GO:0045732 75 0.012
membrane organization GO:0061024 292 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
response to other organism GO:0051707 261 0.012
cell type specific apoptotic process GO:0097285 125 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
multi organism reproductive process GO:0044703 54 0.011
Worm
sister chromatid segregation GO:0000819 54 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
negative regulation of cytoplasmic transport GO:1903650 46 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
establishment of rna localization GO:0051236 39 0.011
regulation of dna metabolic process GO:0051052 153 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
regeneration GO:0031099 4 0.010
response to fungus GO:0009620 4 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
covalent chromatin modification GO:0016569 254 0.010
cellular response to hypoxia GO:0071456 51 0.010
protein export from nucleus GO:0006611 29 0.010

SAE1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.015
neurodegenerative disease DOID:1289 102 0.015
nervous system disease DOID:863 431 0.015
retinal disease DOID:5679 118 0.015
retinal degeneration DOID:8466 89 0.015
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015