Homo sapiens

0 known processes

KIAA1539

KIAA1539

(Aliases: P1.11659_5,FLJ11560,bA182N22.6,RP11-182N22.6)

KIAA1539 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rho protein signal transduction GO:0007266 26 0.512
purine ribonucleoside catabolic process GO:0046130 398 0.457
ribonucleotide catabolic process GO:0009261 405 0.438
purine nucleoside catabolic process GO:0006152 398 0.415
regulation of nucleotide metabolic process GO:0006140 269 0.391
ribonucleoside catabolic process GO:0042454 406 0.390
purine nucleotide catabolic process GO:0006195 405 0.373
positive regulation of gtpase activity GO:0043547 166 0.349
purine ribonucleotide catabolic process GO:0009154 404 0.347
nucleoside phosphate catabolic process GO:1901292 412 0.346
regulation of gtp catabolic process GO:0033124 180 0.316
nucleoside catabolic process GO:0009164 408 0.316
positive regulation of nucleoside metabolic process GO:0045979 186 0.315
purine nucleoside triphosphate metabolic process GO:0009144 412 0.312
regulation of nucleotide catabolic process GO:0030811 205 0.300
purine nucleoside triphosphate catabolic process GO:0009146 392 0.279
ribonucleoside triphosphate metabolic process GO:0009199 412 0.271
glycosyl compound catabolic process GO:1901658 413 0.268
ribonucleoside triphosphate catabolic process GO:0009203 391 0.259
regulation of gtpase activity GO:0043087 180 0.240
purine containing compound catabolic process GO:0072523 411 0.239
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.237
nucleoside triphosphate catabolic process GO:0009143 394 0.237
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.234
guanosine containing compound catabolic process GO:1901069 239 0.232
nucleotide catabolic process GO:0009166 408 0.228
organophosphate catabolic process GO:0046434 430 0.226
positive regulation of nucleotide catabolic process GO:0030813 185 0.225
gtp metabolic process GO:0046039 239 0.223
positive regulation of hydrolase activity GO:0051345 331 0.221
positive regulation of cellular catabolic process GO:0031331 284 0.217
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.195
cellular amine metabolic process GO:0044106 41 0.194
positive regulation of ras gtpase activity GO:0032320 117 0.189
purine ribonucleoside metabolic process GO:0046128 437 0.185
regulation of purine nucleotide catabolic process GO:0033121 205 0.183
regulation of nucleoside metabolic process GO:0009118 209 0.182
regulation of cellular component biogenesis GO:0044087 281 0.177
guanosine containing compound metabolic process GO:1901068 244 0.172
small gtpase mediated signal transduction GO:0007264 78 0.165
gtp catabolic process GO:0006184 237 0.164
positive regulation of catabolic process GO:0009896 310 0.163
regulation of rho protein signal transduction GO:0035023 79 0.151
positive regulation of nucleotide metabolic process GO:0045981 230 0.147
regulation of purine nucleotide metabolic process GO:1900542 264 0.143
nucleoside triphosphate metabolic process GO:0009141 422 0.142
cellular macromolecule catabolic process GO:0044265 380 0.132
regulation of ras gtpase activity GO:0032318 128 0.129
endomembrane system organization GO:0010256 196 0.120
positive regulation of gtp catabolic process GO:0033126 166 0.120
nucleoside monophosphate catabolic process GO:0009125 159 0.118
cell development GO:0048468 328 0.116
regulation of rho gtpase activity GO:0032319 66 0.110
cellular amino acid metabolic process GO:0006520 116 0.107
cell projection organization GO:0030030 252 0.105
amine metabolic process GO:0009308 44 0.102
ras protein signal transduction GO:0007265 73 0.096
protein processing GO:0016485 226 0.096
nucleoside monophosphate metabolic process GO:0009123 191 0.093
regulation of small gtpase mediated signal transduction GO:0051056 156 0.093
atp metabolic process GO:0046034 176 0.092
protein maturation GO:0051604 233 0.092
positive regulation of rho gtpase activity GO:0032321 56 0.091
regulation of cellular ketone metabolic process GO:0010565 50 0.088
cellular component morphogenesis GO:0032989 314 0.087
purine nucleoside monophosphate metabolic process GO:0009126 186 0.081
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.081
membrane organization GO:0061024 292 0.079
protein localization to membrane GO:0072657 160 0.079
atp catabolic process GO:0006200 157 0.076
protein catabolic process GO:0030163 325 0.075
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.071
cellular ketone metabolic process GO:0042180 80 0.071
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
lipid metabolic process GO:0006629 381 0.070
regulation of cell differentiation GO:0045595 393 0.069
negative regulation of cellular component organization GO:0051129 235 0.068
regulation of cellular component movement GO:0051270 334 0.066
cellular response to growth factor stimulus GO:0071363 197 0.064
organelle assembly GO:0070925 176 0.063
modification dependent macromolecule catabolic process GO:0043632 212 0.060
single organism membrane organization GO:0044802 268 0.058
cell morphogenesis GO:0000902 296 0.058
ribonucleoside monophosphate catabolic process GO:0009158 158 0.058
cellular lipid metabolic process GO:0044255 303 0.056
regulation of anatomical structure morphogenesis GO:0022603 286 0.056
negative regulation of catalytic activity GO:0043086 335 0.055
actin cytoskeleton organization GO:0030036 207 0.054
regulation of cell motility GO:2000145 299 0.052
regulation of protein localization GO:0032880 296 0.051
ribonucleoside monophosphate metabolic process GO:0009161 187 0.051
cellular protein catabolic process GO:0044257 261 0.049
microtubule based process GO:0007017 210 0.049
vesicle mediated transport GO:0016192 371 0.048
oogenesis GO:0048477 2 0.047
negative regulation of phosphate metabolic process GO:0045936 267 0.047
positive regulation of cellular component organization GO:0051130 376 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
inorganic ion transmembrane transport GO:0098660 231 0.046
inorganic cation transmembrane transport GO:0098662 194 0.044
biological adhesion GO:0022610 331 0.043
plasma membrane organization GO:0007009 115 0.043
regulation of cell migration GO:0030334 289 0.043
purine nucleoside monophosphate catabolic process GO:0009128 158 0.043
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
oocyte differentiation GO:0009994 2 0.042
regulation of cell morphogenesis GO:0022604 153 0.042
regulation of ras protein signal transduction GO:0046578 155 0.042
multicellular organismal aging GO:0010259 3 0.040
negative regulation of apoptotic process GO:0043066 316 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
circulatory system development GO:0072359 262 0.039
cellular homeostasis GO:0019725 196 0.038
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
regulation of locomotion GO:0040012 329 0.038
chemotaxis GO:0006935 157 0.037
nervous system development GO:0007399 293 0.036
positive regulation of rab gtpase activity GO:0032851 39 0.036
apoptotic signaling pathway GO:0097190 268 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.036
cell adhesion GO:0007155 325 0.036
microtubule cytoskeleton organization GO:0000226 176 0.035
cell matrix adhesion GO:0007160 85 0.035
determination of adult lifespan GO:0008340 2 0.035
taxis GO:0042330 157 0.035
signal transduction by phosphorylation GO:0023014 297 0.035
regulation of dephosphorylation GO:0035303 96 0.034
regulation of proteolysis GO:0030162 293 0.034
cell part morphogenesis GO:0032990 137 0.033
receptor metabolic process GO:0043112 81 0.033
regulation of secretion by cell GO:1903530 177 0.032
circadian behavior GO:0048512 2 0.032
positive regulation of cell projection organization GO:0031346 64 0.031
ubiquitin dependent protein catabolic process GO:0006511 206 0.031
system process GO:0003008 349 0.031
proteasomal protein catabolic process GO:0010498 176 0.031
establishment of protein localization to membrane GO:0090150 121 0.030
regulation of intracellular transport GO:0032386 195 0.030
modification dependent protein catabolic process GO:0019941 209 0.030
female gamete generation GO:0007292 2 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
single organism cellular localization GO:1902580 332 0.030
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
protein autophosphorylation GO:0046777 123 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
negative regulation of organelle organization GO:0010639 126 0.029
positive regulation of locomotion GO:0040017 186 0.029
regulation of cell development GO:0060284 161 0.029
regulation of cell adhesion GO:0030155 166 0.028
regulation of cytoskeleton organization GO:0051493 177 0.028
dephosphorylation GO:0016311 209 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.028
cell projection morphogenesis GO:0048858 129 0.027
response to oxygen containing compound GO:1901700 369 0.027
neuron differentiation GO:0030182 138 0.027
mapk cascade GO:0000165 288 0.027
oocyte development GO:0048599 1 0.027
autophagy GO:0006914 88 0.027
peptidyl serine phosphorylation GO:0018105 101 0.027
locomotory behavior GO:0007626 1 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
cell junction organization GO:0034330 79 0.026
actin filament based process GO:0030029 224 0.026
actin filament organization GO:0007015 128 0.026
histone modification GO:0016570 251 0.026
cytokine production GO:0001816 247 0.025
negative regulation of cell death GO:0060548 345 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
regulation of cell growth GO:0001558 135 0.025
positive regulation of cell migration GO:0030335 172 0.025
cell morphogenesis involved in differentiation GO:0000904 144 0.025
rab protein signal transduction GO:0032482 4 0.024
secretion GO:0046903 254 0.024
cell junction assembly GO:0034329 67 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
regulation of neuron differentiation GO:0045664 70 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.023
regulation of cell cycle process GO:0010564 266 0.023
positive regulation of cellular component movement GO:0051272 181 0.023
anterior posterior axis specification GO:0009948 2 0.023
syncytium formation by plasma membrane fusion GO:0000768 2 0.023
chromatin modification GO:0016568 298 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
exocytosis GO:0006887 71 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
interspecies interaction between organisms GO:0044419 156 0.023
positive regulation of organelle organization GO:0010638 195 0.023
regulation of cell projection organization GO:0031344 107 0.022
multi organism cellular process GO:0044764 156 0.022
regulation of cellular response to growth factor stimulus GO:0090287 76 0.022
protein ubiquitination GO:0016567 314 0.022
protein localization to plasma membrane GO:0072659 93 0.022
lipid localization GO:0010876 106 0.022
positive regulation of developmental process GO:0051094 314 0.022
post embryonic development GO:0009791 2 0.022
secretion by cell GO:0032940 226 0.022
regulation of kinase activity GO:0043549 314 0.021
sulfur compound metabolic process GO:0006790 101 0.021
leukocyte migration GO:0050900 107 0.021
regulation of actin polymerization or depolymerization GO:0008064 56 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
ion transmembrane transport GO:0034220 338 0.021
memory GO:0007613 3 0.021
negative regulation of transferase activity GO:0051348 124 0.021
neurogenesis GO:0022008 169 0.021
regulation of peptidase activity GO:0052547 180 0.020
positive regulation of cell cycle GO:0045787 140 0.020
neuron projection regeneration GO:0031102 1 0.020
neurological system process GO:0050877 163 0.020
macromolecular complex disassembly GO:0032984 60 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
neuromuscular junction development GO:0007528 3 0.020
negative regulation of protein processing GO:0010955 142 0.020
defense response GO:0006952 315 0.019
regulation of protein kinase activity GO:0045859 289 0.019
cellular chemical homeostasis GO:0055082 180 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
negative regulation of catabolic process GO:0009895 104 0.019
regulation of microtubule cytoskeleton organization GO:0070507 61 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
cell growth GO:0016049 160 0.019
cell type specific apoptotic process GO:0097285 125 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
negative regulation of proteolysis GO:0045861 132 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
focal adhesion assembly GO:0048041 30 0.018
nitrogen compound transport GO:0071705 191 0.018
protein acylation GO:0043543 138 0.018
regulation of immune response GO:0050776 201 0.018
nucleoside phosphate biosynthetic process GO:1901293 109 0.018
regulation of rab protein signal transduction GO:0032483 39 0.018
response to cytokine GO:0034097 232 0.018
chromosome segregation GO:0007059 114 0.017
immune response GO:0006955 307 0.017
sensory perception GO:0007600 103 0.017
establishment of protein localization to plasma membrane GO:0090002 68 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
glycerolipid metabolic process GO:0046486 107 0.017
regulation of rab gtpase activity GO:0032313 39 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
segmentation GO:0035282 4 0.017
response to hormone GO:0009725 175 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
negative regulation of protein maturation GO:1903318 142 0.017
maintenance of location GO:0051235 112 0.017
nucleus localization GO:0051647 1 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of cellular response to stress GO:0080135 244 0.016
regeneration GO:0031099 4 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
viral process GO:0016032 146 0.016
alcohol metabolic process GO:0006066 114 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
regulation of mitochondrion organization GO:0010821 54 0.016
myeloid leukocyte migration GO:0097529 62 0.016
regulation of protein transport GO:0051223 213 0.016
viral life cycle GO:0019058 132 0.016
regulation of cell cycle GO:0051726 393 0.016
muscle system process GO:0003012 81 0.016
positive regulation of cell cycle process GO:0090068 106 0.015
positive regulation of transport GO:0051050 336 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
peptidyl serine modification GO:0018209 106 0.015
cardiovascular system development GO:0072358 262 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
neuron development GO:0048666 113 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
positive regulation of cell motility GO:2000147 177 0.015
negative regulation of transport GO:0051051 176 0.015
sensory perception of smell GO:0007608 2 0.015
leukocyte chemotaxis GO:0030595 76 0.015
mitochondrion organization GO:0007005 156 0.015
regulation of phosphatase activity GO:0010921 81 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
regulation of transferase activity GO:0051338 355 0.015
endosomal transport GO:0016197 129 0.015
covalent chromatin modification GO:0016569 254 0.015
intracellular protein transport GO:0006886 270 0.015
cell cycle phase transition GO:0044770 173 0.015
rhythmic behavior GO:0007622 2 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
lipid biosynthetic process GO:0008610 177 0.015
cyclic nucleotide biosynthetic process GO:0009190 61 0.015
regulation of microtubule based process GO:0032886 74 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
associative learning GO:0008306 1 0.015
chemical homeostasis GO:0048878 306 0.015
negative regulation of cellular catabolic process GO:0031330 83 0.015
regulation of cytokine production GO:0001817 232 0.014
cell substrate adherens junction assembly GO:0007045 30 0.014
response to oxygen levels GO:0070482 100 0.014
regulation of response to external stimulus GO:0032101 222 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
spermatid differentiation GO:0048515 4 0.014
generation of neurons GO:0048699 152 0.014
response to wounding GO:0009611 168 0.014
mitotic cell cycle GO:0000278 326 0.014
lamellipodium organization GO:0097581 30 0.014
stress fiber assembly GO:0043149 40 0.014
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.014
actin filament bundle organization GO:0061572 54 0.014
negative regulation of cell cycle GO:0045786 193 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.013
negative regulation of protein catabolic process GO:0042177 59 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
cation transmembrane transport GO:0098655 238 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
protein oligomerization GO:0051259 173 0.013
response to other organism GO:0051707 261 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
calcium ion transmembrane transport GO:0070588 76 0.013
regulation of actin filament based process GO:0032970 141 0.013
response to abiotic stimulus GO:0009628 336 0.013
tripartite regional subdivision GO:0007351 2 0.013
response to growth factor GO:0070848 205 0.013
protein targeting GO:0006605 187 0.013
cellular component disassembly GO:0022411 92 0.013
actomyosin structure organization GO:0031032 59 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
regulation of defense response GO:0031347 154 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
central nervous system development GO:0007417 123 0.012
spermatid development GO:0007286 4 0.012
protein complex disassembly GO:0043241 52 0.012
head development GO:0060322 108 0.012
negative regulation of cell motility GO:2000146 104 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
negative regulation of dephosphorylation GO:0035305 63 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of protein processing GO:0070613 150 0.012
epithelium migration GO:0090132 119 0.012
regulation of protein catabolic process GO:0042176 155 0.012
regulation of growth GO:0040008 165 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
positive regulation of axon extension GO:0045773 4 0.012
long chain fatty acid metabolic process GO:0001676 30 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
peptidyl lysine modification GO:0018205 144 0.012
ion homeostasis GO:0050801 230 0.012
positive regulation of neuron differentiation GO:0045666 40 0.012
chromatin organization GO:0006325 351 0.012
metal ion transport GO:0030001 272 0.012
circulatory system process GO:0003013 113 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
regulation of actin filament bundle assembly GO:0032231 36 0.012
cellular lipid catabolic process GO:0044242 65 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.011
ossification GO:0001503 121 0.011
regulation of cell junction assembly GO:1901888 29 0.011
endocytosis GO:0006897 159 0.011
protein dephosphorylation GO:0006470 81 0.011
regulation of cellular component size GO:0032535 82 0.011
cell substrate adhesion GO:0031589 132 0.011
actin filament bundle assembly GO:0051017 54 0.011
negative regulation of kinase activity GO:0033673 106 0.011
peptidyl threonine modification GO:0018210 45 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
cation transport GO:0006812 331 0.011
vacuole organization GO:0007033 44 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
ribonucleotide biosynthetic process GO:0009260 81 0.011
transmembrane transport GO:0055085 399 0.011
inflammatory response GO:0006954 79 0.011
meiotic chromosome segregation GO:0045132 4 0.011
positive regulation of cell adhesion GO:0045785 84 0.011
response to bacterium GO:0009617 144 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
wnt signaling pathway GO:0016055 156 0.011
regulation of protein maturation GO:1903317 150 0.011
regulation of cell substrate adhesion GO:0010810 68 0.011
cellular cation homeostasis GO:0030003 163 0.011
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.011
adult locomotory behavior GO:0008344 1 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
membrane lipid metabolic process GO:0006643 53 0.011
regulation of inflammatory response GO:0050727 46 0.010
regulation of jnk cascade GO:0046328 73 0.010
organic anion transport GO:0015711 103 0.010
establishment of cell polarity GO:0030010 22 0.010
regulation of anatomical structure size GO:0090066 101 0.010
regulation of cell maturation GO:1903429 3 0.010
positive regulation of immune response GO:0050778 159 0.010
ribose phosphate biosynthetic process GO:0046390 82 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
maintenance of protein location GO:0045185 57 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
cellular ion homeostasis GO:0006873 168 0.010
myosin filament assembly GO:0031034 2 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010

KIAA1539 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.107
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
myopathy DOID:423 104 0.029
muscular disease DOID:0080000 114 0.029
muscular dystrophy DOID:9884 51 0.029
musculoskeletal system disease DOID:17 223 0.029
muscle tissue disease DOID:66 113 0.029
disease of metabolism DOID:0014667 295 0.024
inherited metabolic disorder DOID:655 242 0.024
bone disease DOID:0080001 88 0.020
connective tissue disease DOID:65 109 0.020
hypersensitivity reaction disease DOID:0060056 25 0.018
sensory system disease DOID:0050155 203 0.011