Homo sapiens

9 known processes

SDHB

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

(Aliases: SDH2,SDH1,IP,PGL4,SDHIP,SDH,FLJ92337)

SDHB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleoside triphosphate metabolic process GO:0009144 412 0.672
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.653
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.647
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.540
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.531
Fly
purine nucleoside monophosphate metabolic process GO:0009126 186 0.527
Fly
cellular respiration GO:0045333 21 0.526
Rat Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.521
Fly
ribonucleoside monophosphate metabolic process GO:0009161 187 0.458
Fly
post embryonic development GO:0009791 2 0.450
Worm
oxidation reduction process GO:0055114 396 0.401
Rat Fly
atp metabolic process GO:0046034 176 0.327
Fly
nervous system development GO:0007399 293 0.318
generation of precursor metabolites and energy GO:0006091 68 0.254
Rat Fly
atp synthesis coupled electron transport GO:0042773 4 0.249
Fly
determination of adult lifespan GO:0008340 2 0.206
Worm
adult locomotory behavior GO:0008344 1 0.156
vesicle mediated transport GO:0016192 371 0.147
lipid localization GO:0010876 106 0.140
oxidative phosphorylation GO:0006119 10 0.130
Fly
energy derivation by oxidation of organic compounds GO:0015980 43 0.120
Rat Fly
succinate metabolic process GO:0006105 1 0.118
Rat
aerobic respiration GO:0009060 7 0.109
negative regulation of cell death GO:0060548 345 0.104
regulation of purine nucleotide metabolic process GO:1900542 264 0.099
cellular amine metabolic process GO:0044106 41 0.093
regulation of nucleoside metabolic process GO:0009118 209 0.093
regulation of cellular amine metabolic process GO:0033238 11 0.087
microtubule cytoskeleton organization GO:0000226 176 0.083
cellular amino acid metabolic process GO:0006520 116 0.082
embryo development GO:0009790 123 0.079
Worm
organophosphate biosynthetic process GO:0090407 163 0.078
negative regulation of apoptotic process GO:0043066 316 0.076
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
amine metabolic process GO:0009308 44 0.074
regulation of cellular ketone metabolic process GO:0010565 50 0.069
regulation of cellular amino acid metabolic process GO:0006521 6 0.068
cellular ketone metabolic process GO:0042180 80 0.067
nucleoside phosphate biosynthetic process GO:1901293 109 0.065
ribonucleotide catabolic process GO:0009261 405 0.064
lipid metabolic process GO:0006629 381 0.062
glycosyl compound catabolic process GO:1901658 413 0.061
locomotory behavior GO:0007626 1 0.061
mitochondrion organization GO:0007005 156 0.059
carbohydrate derivative biosynthetic process GO:1901137 207 0.058
respiratory electron transport chain GO:0022904 7 0.058
Rat Fly
ribose phosphate biosynthetic process GO:0046390 82 0.056
negative regulation of apoptotic signaling pathway GO:2001234 97 0.055
cation transport GO:0006812 331 0.054
negative regulation of phosphorus metabolic process GO:0010563 267 0.054
organonitrogen compound biosynthetic process GO:1901566 200 0.053
negative regulation of programmed cell death GO:0043069 321 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.050
cellular chemical homeostasis GO:0055082 180 0.050
regulation of nucleotide catabolic process GO:0030811 205 0.050
mitochondrial respiratory chain complex assembly GO:0033108 23 0.049
nucleoside monophosphate metabolic process GO:0009123 191 0.048
Fly
mitochondrial transport GO:0006839 60 0.047
negative regulation of catalytic activity GO:0043086 335 0.045
chemical homeostasis GO:0048878 306 0.045
regulation of purine nucleotide catabolic process GO:0033121 205 0.044
spinal cord development GO:0021510 4 0.043
purine ribonucleoside catabolic process GO:0046130 398 0.042
reactive oxygen species metabolic process GO:0072593 75 0.042
growth GO:0040007 202 0.041
nucleoside catabolic process GO:0009164 408 0.041
purine nucleotide biosynthetic process GO:0006164 84 0.040
regulation of membrane potential GO:0042391 95 0.040
metal ion homeostasis GO:0055065 169 0.039
cation transmembrane transport GO:0098655 238 0.039
maintenance of location GO:0051235 112 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
circulatory system development GO:0072359 262 0.037
regulation of mitochondrial membrane potential GO:0051881 23 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.036
cellular calcium ion homeostasis GO:0006874 117 0.036
ribonucleoside catabolic process GO:0042454 406 0.035
positive regulation of nucleoside metabolic process GO:0045979 186 0.035
ras protein signal transduction GO:0007265 73 0.035
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.034
proximal tubule development GO:0072014 1 0.034
cellular cation homeostasis GO:0030003 163 0.034
female gamete generation GO:0007292 2 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
organophosphate catabolic process GO:0046434 430 0.034
response to oxidative stress GO:0006979 121 0.033
small molecule biosynthetic process GO:0044283 157 0.033
lipid biosynthetic process GO:0008610 177 0.033
neuromuscular junction development GO:0007528 3 0.032
ion homeostasis GO:0050801 230 0.032
inorganic cation transmembrane transport GO:0098662 194 0.031
cofactor metabolic process GO:0051186 87 0.031
steroid metabolic process GO:0008202 94 0.031
protein oligomerization GO:0051259 173 0.031
multicellular organismal aging GO:0010259 3 0.030
Worm
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.030
Fly
purine ribonucleoside biosynthetic process GO:0046129 23 0.029
response to hormone GO:0009725 175 0.029
cellular homeostasis GO:0019725 196 0.029
nucleotide catabolic process GO:0009166 408 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.028
cellular metal ion homeostasis GO:0006875 146 0.028
apoptotic mitochondrial changes GO:0008637 57 0.028
hydrogen transport GO:0006818 23 0.028
monovalent inorganic cation transport GO:0015672 128 0.028
negative regulation of protein metabolic process GO:0051248 391 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
cation homeostasis GO:0055080 189 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
regeneration GO:0031099 4 0.026
membrane organization GO:0061024 292 0.026
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.026
ion transmembrane transport GO:0034220 338 0.025
apoptotic signaling pathway GO:0097190 268 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
single organism cellular localization GO:1902580 332 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
regulation of kinase activity GO:0043549 314 0.025
positive regulation of cell death GO:0010942 263 0.025
cellular ion homeostasis GO:0006873 168 0.025
tube development GO:0035295 125 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
positive regulation of protein kinase activity GO:0045860 190 0.024
cofactor transport GO:0051181 11 0.024
embryo development ending in birth or egg hatching GO:0009792 34 0.024
Worm
lipid oxidation GO:0034440 33 0.024
purine nucleoside catabolic process GO:0006152 398 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
mitotic cell cycle process GO:1903047 286 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
gtp catabolic process GO:0006184 237 0.023
purine containing compound biosynthetic process GO:0072522 88 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
positive regulation of phosphorylation GO:0042327 394 0.022
regulation of oxidoreductase activity GO:0051341 43 0.022
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.022
mitotic cell cycle GO:0000278 326 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
lipid storage GO:0019915 28 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.021
microtubule based process GO:0007017 210 0.021
purine nucleoside biosynthetic process GO:0042451 23 0.021
endocytosis GO:0006897 159 0.021
dicarboxylic acid metabolic process GO:0043648 29 0.021
Rat
purine containing compound catabolic process GO:0072523 411 0.021
negative regulation of catabolic process GO:0009895 104 0.021
spermatid differentiation GO:0048515 4 0.020
regulation of transferase activity GO:0051338 355 0.020
cell growth GO:0016049 160 0.020
response to antibiotic GO:0046677 15 0.020
cell cell signaling GO:0007267 155 0.020
lung growth GO:0060437 2 0.020
negative regulation of transport GO:0051051 176 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
anatomical structure homeostasis GO:0060249 100 0.019
receptor mediated endocytosis GO:0006898 84 0.019
electron transport chain GO:0022900 8 0.019
Rat Fly
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.019
protein maturation GO:0051604 233 0.019
alcohol biosynthetic process GO:0046165 52 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
cellular component morphogenesis GO:0032989 314 0.019
regulation of gtp catabolic process GO:0033124 180 0.018
inner ear morphogenesis GO:0042472 4 0.018
cell differentiation in spinal cord GO:0021515 1 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
positive regulation of transferase activity GO:0051347 227 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
mitochondrial calcium ion homeostasis GO:0051560 11 0.018
sensory perception GO:0007600 103 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
mitochondrial membrane organization GO:0007006 40 0.018
cellular response to oxidative stress GO:0034599 85 0.018
cellular protein catabolic process GO:0044257 261 0.018
segmentation GO:0035282 4 0.018
negative regulation of nucleotide metabolic process GO:0045980 29 0.017
transmembrane transport GO:0055085 399 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
regulation of atp metabolic process GO:1903578 29 0.017
alcohol metabolic process GO:0006066 114 0.017
negative regulation of organelle organization GO:0010639 126 0.017
striated muscle tissue development GO:0014706 59 0.017
reproductive structure development GO:0048608 55 0.017
mitochondrial electron transport nadh to ubiquinone GO:0006120 2 0.017
nucleotide biosynthetic process GO:0009165 109 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
cofactor biosynthetic process GO:0051188 31 0.016
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
lipid catabolic process GO:0016042 84 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
aging GO:0007568 66 0.016
Worm
regulation of ras protein signal transduction GO:0046578 155 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
regulation of gtpase activity GO:0043087 180 0.016
immune system development GO:0002520 195 0.016
steroid biosynthetic process GO:0006694 46 0.016
mating GO:0007618 1 0.016
gtp metabolic process GO:0046039 239 0.016
head development GO:0060322 108 0.016
organelle localization GO:0051640 84 0.015
peptidyl serine modification GO:0018209 106 0.015
reproduction GO:0000003 63 0.015
Worm
cellular divalent inorganic cation homeostasis GO:0072503 128 0.015
biological adhesion GO:0022610 331 0.015
carboxylic acid transport GO:0046942 63 0.015
positive regulation of kinase activity GO:0033674 204 0.015
peptidyl serine phosphorylation GO:0018105 101 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
neurological system process GO:0050877 163 0.015
epithelium development GO:0060429 227 0.015
nitrogen compound transport GO:0071705 191 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
ribonucleoside biosynthetic process GO:0042455 25 0.015
protein localization to organelle GO:0033365 280 0.015
system process GO:0003008 349 0.015
establishment of organelle localization GO:0051656 59 0.015
negative regulation of mitochondrion organization GO:0010823 22 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.014
oogenesis GO:0048477 2 0.014
developmental growth GO:0048589 48 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
organic anion transport GO:0015711 103 0.014
nadh dehydrogenase complex assembly GO:0010257 16 0.014
metal ion transport GO:0030001 272 0.014
regulation of proteolysis GO:0030162 293 0.014
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.013
organic hydroxy compound biosynthetic process GO:1901617 71 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
regulation of peptidyl serine phosphorylation GO:0033135 50 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
innate immune response GO:0045087 178 0.013
secretion by cell GO:0032940 226 0.013
tissue regeneration GO:0042246 3 0.013
reproductive system development GO:0061458 56 0.013
myosin filament organization GO:0031033 2 0.013
ventral spinal cord development GO:0021517 1 0.013
positive regulation of cell cycle GO:0045787 140 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
immune response GO:0006955 307 0.013
response to reactive oxygen species GO:0000302 61 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
cytoplasmic transport GO:0016482 379 0.012
rho protein signal transduction GO:0007266 26 0.012
protein kinase b signaling GO:0043491 69 0.012
calcium ion homeostasis GO:0055074 122 0.012
hydrogen ion transmembrane transport GO:1902600 15 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
mapk cascade GO:0000165 288 0.012
blood vessel morphogenesis GO:0048514 162 0.012
actin filament based process GO:0030029 224 0.012
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.012
hindbrain development GO:0030902 3 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cell adhesion GO:0007155 325 0.012
calcium ion transport GO:0006816 147 0.012
regulation of neuroblast proliferation GO:1902692 3 0.012
regulation of intracellular transport GO:0032386 195 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.011
anion transport GO:0006820 161 0.011
atp catabolic process GO:0006200 157 0.011
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.011
negative regulation of nucleotide catabolic process GO:0030812 16 0.011
behavior GO:0007610 112 0.011
positive regulation of immune system process GO:0002684 283 0.011
neurogenesis GO:0022008 169 0.011
negative regulation of growth GO:0045926 97 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
tetrapyrrole biosynthetic process GO:0033014 7 0.011
central nervous system development GO:0007417 123 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
positive regulation of developmental process GO:0051094 314 0.011
branch elongation of an epithelium GO:0060602 3 0.011
protein catabolic process GO:0030163 325 0.011
osteoblast differentiation GO:0001649 92 0.011
cytokine production GO:0001816 247 0.011
atp biosynthetic process GO:0006754 11 0.011
nucleoside triphosphate biosynthetic process GO:0009142 20 0.011
atp transport GO:0015867 4 0.011
embryonic organ development GO:0048568 36 0.011
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.011
axis elongation GO:0003401 4 0.011
fatty acid metabolic process GO:0006631 115 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
cell part morphogenesis GO:0032990 137 0.011
regulation of cellular response to stress GO:0080135 244 0.010
regulation of atpase activity GO:0043462 25 0.010
protein processing GO:0016485 226 0.010
regulation of growth GO:0040008 165 0.010
dna replication GO:0006260 116 0.010
action potential GO:0001508 34 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
organic acid transport GO:0015849 65 0.010
myosin filament assembly GO:0031034 2 0.010
negative regulation of nucleoside metabolic process GO:0045978 18 0.010
blastoderm segmentation GO:0007350 2 0.010
protein homooligomerization GO:0051260 100 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
regulation of cell differentiation GO:0045595 393 0.010
regulation of protein kinase activity GO:0045859 289 0.010

SDHB disease predictions

Disease DO term ID Size Probability Func Analog Org
leigh disease DOID:3652 16 0.905
disease of metabolism DOID:0014667 295 0.905
mitochondrial metabolism disease DOID:700 29 0.905
inherited metabolic disorder DOID:655 242 0.905
myopathy DOID:423 104 0.465
muscular disease DOID:0080000 114 0.465
heart disease DOID:114 68 0.465
cardiomyopathy DOID:0050700 50 0.465
cardiovascular system disease DOID:1287 106 0.465
musculoskeletal system disease DOID:17 223 0.465
muscle tissue disease DOID:66 113 0.465
intrinsic cardiomyopathy DOID:0060036 50 0.261
disease of cellular proliferation DOID:14566 174 0.100
endocrine gland cancer DOID:170 26 0.097
cancer DOID:162 167 0.097
organ system cancer DOID:0050686 164 0.097
central nervous system disease DOID:331 186 0.021
nervous system disease DOID:863 431 0.021
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
retinal disease DOID:5679 118 0.012
retinal degeneration DOID:8466 89 0.012
immune system disease DOID:2914 155 0.011
neurodegenerative disease DOID:1289 102 0.010
gastrointestinal system cancer DOID:3119 52 0.003
cell type benign neoplasm DOID:0060084 10 0.002
phaeochromocytoma DOID:0050771 8 0.002
benign neoplasm DOID:0060072 18 0.002
gastrointestinal stromal tumor DOID:9253 4 0.001